KEGG T02447: CCG32351

Klebsiella aerogenes EA1509E: CCG32351

Entry

CCG32351          CDS       T02447

Name

(GenBank) IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)

K00602

phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]

Organism

ear Klebsiella aerogenes EA1509E

Pathway

ear00230

Purine metabolism

ear00670

One carbon pool by folate

ear01100

Metabolic pathways

ear01110

Biosynthesis of secondary metabolites

Module

ear_M00048

De novo purine biosynthesis, PRPP + glutamine => IMP

Brite

KEGG Orthology (KO) [BR:ear00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    CCG32351
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CCG32351
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ear04147]
    CCG32351
Enzymes [BR:ear01000]
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     CCG32351
3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     CCG32351
Exosome [BR:ear04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   CCG32351

SSDB

Motif

Pfam:

AICARFT_IMPCHas MGS

Other DBs

NCBI-ProteinID:

CCG32351

Position

3678708..3680324

AA seq 538 aa
MFKSWGFNTMQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLADKGLPV
TEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMQQHGIAPIDMVVVNLYPFAQT
VAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIINEMDANEGSLTLDT
RFDLAIKAFEHTAAYDSMIANYFGSMVPSYHGESKEAAGRFPRTLNLNFIKKQDMRYGEN
SHQQAAFYIEENVKEASVATATQLQGKALSYNNIADTDAALECVKEFNEPACVIVKHANP
CGVAVSDSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEE
ALKITAAKQNVRVLVCGQWDARVAGLDFKRVNGGLLVQDRDLGMVTAGELRVVSKRQPSE
QELRDALFCWKVAKFVKSNAIVYAKDNMTIGIGAGQMSRVYSAKIAGIKAGDEGLEVKGS
AMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDEEVIAAADEHGIAMIFTDMRHFRH

NT seq 1617 nt +upstreamnt +downstreamnt
atgttcaaatcctggggatttaataccatgcaacaacgtcgtccagtccgccgcgctctg
ctcagtgtttctgacaaggccggtatcgtcgaattcgcgcaggcgctttccgctcgtggt
gtcgagctgctgtccaccggcggcaccgctcgcctgctggcagataaaggcctgccggtt
accgaagtctctgactacaccggtttccccgaaatgatggatggacgcgtgaagaccctg
catccgaaagtacacggcggcatcctcggtcgtcgcggtcaggatgacggtatcatgcag
caacacggtatcgcgcctatcgatatggttgtcgttaacctttatccgtttgcccagacc
gtcgctcgtgaagggtgttcgctggaagacgcggtggaaaacatcgatatcggcggcccg
accatggtgcgctctgcggcgaagaaccataaagacgtcgccatcgtggttaagagcagc
gactacgacgccatcattaatgagatggacgccaacgaaggttccctcacgctggacacc
cgcttcgacctcgccattaaagccttcgaacacaccgccgcttacgacagcatgatcgct
aactacttcggtagcatggttccgtcctatcacggcgaaagcaaagaagccgctggccgc
ttcccgcgtaccctgaatctgaacttcattaagaagcaggatatgcgctacggcgaaaac
agccaccagcaggctgccttctatatagaagagaatgtaaaagaagcctccgtggctacc
gccacccagctgcagggcaaagcgctctcctataacaatattgccgataccgatgcggcg
ctggaatgcgtgaaagagtttaacgagccggcctgcgttatcgttaagcatgccaacccg
tgcggcgttgccgtcagcgactcgatcctcgacgcctacgatcgcgcatacaaaaccgac
ccaacctccgcgttcggcggcatcatcgcctttaaccgcgagctggatgctgaaaccgcg
caggcgatcatctctcgccagttcgtcgaagtgatcatcgcgccatccgctagcgaagaa
gcgctgaaaatcaccgccgctaagcagaacgtccgcgtactggtctgcggccagtgggat
gctcgcgtcgcgggtctcgatttcaaacgtgtcaatggcggcttgctggttcaggaccgc
gatctcggtatggtcaccgcgggcgaactgcgcgtggttagcaaacgtcagccgagcgag
caagagctgcgcgatgcgctgttctgctggaaagtggcgaaattcgtcaaatccaacgcc
atcgtttatgccaaagataatatgaccatcggtataggcgccggtcagatgagccgcgtc
tactcagcgaaaattgccgggattaaagccggtgacgaaggtctggaagtgaaaggttcc
gccatggcctctgacgctttcttcccgttccgcgatggtattgatgccgcagccgcagta
ggcatcacctgcgttatccaaccgggcggttctatccgcgacgaagaagtaattgccgcc
gcggacgaacatggtatcgccatgatcttcaccgacatgcgccacttccgccattaa

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