KEGG   ENZYME: 1.1.99.6Help
Entry
EC 1.1.99.6                 Enzyme                                 
Name
D-2-hydroxy-acid dehydrogenase;
D-2-hydroxy acid dehydrogenase;
(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With other acceptors
BRITE hierarchy
Sysname
(R)-2-hydroxy-acid:acceptor 2-oxidoreductase
Reaction(IUBMB)
(R)-lactate + acceptor = pyruvate + reduced acceptor [RN:R00297]
Reaction(KEGG)
Substrate
(R)-lactate [CPD:C00256];
acceptor [CPD:C00028]
Product
pyruvate [CPD:C00022];
reduced acceptor [CPD:C00030]
Comment
A zinc flavoprotein (FAD). Acts on a variety of (R)-2-hydroxy acids.
Reference
1  [PMID:13901630]
  Authors
GREGOLIN C, SINGER TP, KEARNEY EB, BOERI E.
  Title
The formation and enzymatic properties of the various lactic dehydrogenases of yeast.
  Journal
Ann. N. Y. Acad. Sci. 94 (1961) 780-97.
  Organism
Saccharomyces cerevisiae [GN:sce]
Reference
2  [PMID:13729965]
  Authors
NYGAARD AP.
  Title
D(-)-Lactic cytochrome c reductase, a flavo-protein from yeast.
  Journal
J. Biol. Chem. 236 (1961) 920-5.
  Organism
Saccharomyces cerevisiae [GN:sce]
Reference
3  [PMID:13839714]
  Authors
TUBBS PK, GREVILLE GD.
  Title
Dehydrogenation of D-lactate by a soluble enzyme from kidney mitochondria.
  Journal
Biochim. Biophys. Acta. 34 (1959) 290-1.
  Organism
Oryctolagus cuniculus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-83-5
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