| Entry |
|
|---|
| Name |
laccase;
urishiol oxidase;
urushiol oxidase;
p-diphenol oxidase |
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| Class |
Oxidoreductases;
Acting on diphenols and related substances as donors;
With oxygen as acceptor
 |
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| Sysname |
benzenediol:oxygen oxidoreductase |
|---|
| Reaction(IUBMB) |
4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O [RN:R00083] |
|---|
| Reaction(KEGG) |
R00083
 |
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| Substrate |
benzenediol [CPD:C01785];
O2 [CPD:C00007] |
|---|
| Product |
benzosemiquinone [CPD:C05309];
H2O [CPD:C00001] |
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| Cofactor |
Copper [CPD:C00070] |
|---|
| Comment |
A group of multi-copper proteins of low specificity acting on both
o- and p-quinols, and often acting also on aminophenols and
phenylenediamine. The semiquinone may react further either
enzymically or non-enzymically. |
|---|
| Orthology |
KO: K05909 |
|---|
| Genes |
DHA: DEHA0E13332g
PIC: PICST_79365(FET3)
MGR: MGG_00551 MGG_11608
AFM: AFUA_1G15670 AFUA_4G14490 AFUA_5G03790
CNE: CNG01240
UMA: UM00105.1 UM05861.1
TTH: TTC1370
 |
|---|
| Structures |
PDB: 1A65 1GW0 1GYC 1HFU 1KYA 1V10 2H5U 2HRG 2HRH 2IH8
2IH9 2Q9O 2QT6 2VDS 2VDZ 2VE0 3CG8 3DIV 3DKH 3FPX
3FU7 3FU8 3FU9 |
|---|
Reference
Authors
Title
Journal
|
1
Dawson, C.R. and Tarpley, W.B.
The copper oxidases.
In: Sumner, J.B. and Myrback, K. (Eds.), The Enzymes, 1st ed., vol.
2, Academic Press, New York, 1951, p. 454-498. |
|---|
Reference
Authors
Title
Journal
|
2
Keilin, D. and Mann, T.
Laccase, a blue copper-protein oxidase from the latex of Rhus
succedanea.
Nature (Lond.) 143 (1939) 23-24. |
|---|
Reference
Authors
Title
Journal
|
3
Malmstrom, B.G., Andreasson, L.-E. and Reinhammar, B.
Copper-containing oxidases and superoxide dismutase.
In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 12, Academic
Press, New York, 1975, p. 507-579. |
|---|
Reference
Authors
Title
Journal
|
4
Mayer, A.M. and Harel, E.
Polyphenol oxidases in plants.
Phytochemistry 18 (1979) 193-215. |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:13584395]
NAKAMURA T.
Purification and physico-chemical properties of laccase.
Biochim. Biophys. Acta. 30 (1958) 44-52.
Rhus vernicifera |
|---|
Reference
Authors
Title
Journal
Organism
|
6 [PMID:13618260]
NAKAMURA T.
Stoichiometric studies on the action of laccase.
Biochim. Biophys. Acta. 30 (1958) 538-42.
Rhus vernicifera |
|---|
Reference
Authors
Title
Journal
Organism
|
7 [PMID:14304827]
PEISACH J, LEVINE WG.
A COMPARISON OF THE ENZYMIC ACTIVITIES OF PIG CERULOPLASMIN AND RHUS
VERNICIFERA LACCASE.
J. Biol. Chem. 240 (1965) 2284-9.
Sus scofa [GN:ssc], Rhus vernicifera |
|---|
Reference
Authors
Title
Journal
|
8
Reinhammar, B. and Malmstrom, B.G.
"Blue" copper-containing oxidases.
In: Spiro, T.G. (Ed.), Copper Proteins, Copper Proteins, New York,
1981, p. 109-149. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.10.3.2
IUBMB Enzyme Nomenclature: 1.10.3.2
ExPASy - ENZYME nomenclature database: 1.10.3.2
UM-BBD (Biocatalysis/Biodegradation Database): 1.10.3.2
BRENDA, the Enzyme Database: 1.10.3.2
CAS: 80498-15-3 |
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