KEGG   ENZYME: 1.13.11.75Help
Entry
EC 1.13.11.75               Enzyme                                 

Name
all-trans-8'-apo-beta-carotenal 15,15'-oxygenase;
Diox1;
ACO;
8'-apo-beta-carotenal 15,15'-oxygenase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
all-trans-8'-apo-beta-carotenal:oxygen 15,15'-oxidoreductase (bond-cleaving)
Reaction(IUBMB)
all-trans-8'-apo-beta-carotenal + O2 = all-trans-retinal + (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial [RN:R09601]
Reaction(KEGG)
Substrate
all-trans-8'-apo-beta-carotenal [CPD:C19728];
O2 [CPD:C00007]
Product
all-trans-retinal [CPD:C00376];
(2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial [CPD:C19729]
Comment
Contains an Fe2+-4His arrangement. The enzyme is involved in retinal biosynthesis in bacteria [2].
History
EC 1.13.11.75 created 2010 as EC 1.14.99.41, transferred 2013 to EC 1.13.11.75
Orthology
K00464  all-trans-8'-apo-beta-carotenal 15,15'-oxygenase
Genes
CRE: CHLREDRAFT_144745 CHLREDRAFT_151463
VCN: VOLCADRAFT_88605 VOLCADRAFT_95405
MNG: MNEG_12302
OLU: OSTLU_30717
OTA: OT_ostta03g03900
BPG: Bathy09g04190
MIS: MICPUN_56538
MPP: MICPUCDRAFT_13068
CSL: COCSUDRAFT_16838 COCSUDRAFT_62551
APRO: F751_3391
PLU: plu4336
APAC: S7S_04700
GSU: GSU3417
GME: Gmet_2446
BMX: BMS_3062
BVR: BVIR_2448
MPA: MAP_1324
MAO: MAP4_2523
MAVI: RC58_12545
MAVU: RE97_12565
MAV: MAV_3153
MAVD: NF84_14175
MAVR: LA63_14330
MAVA: LA64_14325
MIT: OCO_29960
MIA: OCU_29870
MID: MIP_04425
MYO: OEM_29180
MIR: OCQ_30630
MVQ: MYVA_0230
MCHE: BB28_21845
MSTE: MSTE_04419
TPR: Tpau_3944
SYN: sll1541
SYY: SYNGTS_1854(sll1541)
SYT: SYNGTI_1854(sll1541)
SYS: SYNPCCN_1853(sll1541)
SYQ: SYNPCCP_1853(sll1541)
SYW: SYNW0227
SYC: syc1315_d
SYG: sync_0261
CYA: CYA_1068
CYB: CYB_0263
SYNR: KR49_10070
SYND: KR52_01365
TEL: tll0015
THN: NK55_09420(diox1)
PMA: Pro_0312
PMM: PMM0280
PMT: PMT_1879
PRC: EW14_0324
PRM: EW15_0373
MAR: MAE_09040
MPK: VL20_129
CYL: AA637_10445(diox1)
GEE: GM3708_35
TER: Tery_3212
GVI: gll3689
GLJ: GKIL_0836(diox1)
ANA: all4284
AVA: Ava_1236
CALH: IJ00_22530
CTHE: Chro_2748
 » show all
Taxonomy
Reference
1  [PMID:15686550]
  Authors
Ruch S, Beyer P, Ernst H, Al-Babili S
  Title
Retinal biosynthesis in Eubacteria: in vitro characterization of a novel carotenoid oxygenase from Synechocystis sp. PCC 6803.
  Journal
Mol. Microbiol. 55 (2005) 1015-24.
  Sequence
[syn:sll1541]
Reference
2  [PMID:15821095]
  Authors
Kloer DP, Ruch S, Al-Babili S, Beyer P, Schulz GE
  Title
The structure of a retinal-forming carotenoid oxygenase.
  Journal
Science. 308 (2005) 267-9.
  Sequence
[syn:sll1541]
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.75
IUBMB Enzyme Nomenclature: 1.13.11.75
ExPASy - ENZYME nomenclature database: 1.13.11.75
BRENDA, the Enzyme Database: 1.13.11.75

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