3,4-dihydroxyphenylalanine oxidative deaminase;
3,4-dihydroxy-L-phenylalanine: oxidative deaminase;
oxidative deaminase;
DOPA oxidative deaminase;
DOPAODA

Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2;
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

3,4-dihydroxy-L-phenylalanine:oxygen oxidoreductase (deaminating)

2 L-dopa + O2 = 2 3,4-dihydroxyphenylpyruvate + 2 NH3 [RN:R08920]

R08920

L-dopa [CPD:C00355];
O2 [CPD:C00007]

This enzyme is one of the three enzymes involved in L-dopa (3,4-dihydroxy-L-phenylalanine) catabolism in the non-oxygenic phototrophic bacterium Rubrivivax benzoatilyticus OU5 (and not Rhodobacter sphaeroides OU5 as had been thought [1]), the other two being EC 4.3.1.22 (dihydroxyphenylalanine reductive deaminase) and EC 2.6.1.49 (3,4-dihydroxyphenylalanine transaminase). In addition to L-dopa, the enzyme can also use L-tyrosine, L-phenylalanine, L-tryptophan and glutamate as substrate, but more slowly. The enzyme is inhibited by NADH and 2-oxoglutarate.

1  [PMID:18923551]

Ranjith NK, Ramana ChV, Sasikala Ch

Purification and characterization of 3,4-dihydroxyphenylalanine oxidative deaminase from Rhodobacter sphaeroides OU5.

Can. J. Microbiol. 54 (2008) 829-34.

Rhodobacter sphaeroides