KEGG   ENZYME: 1.14.11.2Help
Entry
EC 1.14.11.2                Enzyme                                 
Name
procollagen-proline dioxygenase;
protocollagen hydroxylase;
proline hydroxylase;
proline,2-oxoglutarate 4-dioxygenase;
collagen proline hydroxylase;
hydroxylase, collagen proline;
peptidyl proline hydroxylase;
proline protocollagen hydroxylase;
proline, 2-oxoglutarate dioxygenase;
prolyl hydroxylase;
prolylprotocollagen dioxygenase;
prolylprotocollagen hydroxylase;
protocollagen proline 4-hydroxylase;
protocollagen proline dioxygenase;
protocollagen proline hydroxylase;
protocollagen prolyl hydroxylase;
prolyl 4-hydroxylase;
prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating;
procollagen-proline 4-dioxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
BRITE hierarchy
Sysname
procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating)
Reaction(IUBMB)
procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2 [RN:R03219]
Reaction(KEGG)
R03219;
(other) R01252
Show
Substrate
procollagen L-proline [CPD:C01078];
2-oxoglutarate [CPD:C00026];
O2 [CPD:C00007]
Product
procollagen trans-4-hydroxy-L-proline [CPD:C04398];
succinate [CPD:C00042];
CO2 [CPD:C00011]
Comment
Requires Fe2+ and ascorbate.
History
EC 1.14.11.2 created 1972, modified 1981, modified 1983
Pathway
Arginine and proline metabolism
Metabolic pathways
Orthology
K00472  
prolyl 4-hydroxylase
Genes
HSA: 
283208(P4HA3) 5033(P4HA1) 8974(P4HA2)
PTR: 
450891(P4HA1) 462047(P4HA2) 748564(P4HA3)
PPS: 
100976439(P4HA3) 100992298(P4HA1) 100993331(P4HA2)
GGO: 
101131612(P4HA1) 101133984(P4HA2) 101143792(P4HA3)
PON: 
100172658(P4HA1) 100433561(P4HA3) 100448172(P4HA2)
MCC: 
707157(P4HA2) 707927(P4HA1) 718872
MCF: 
MMU: 
18451(P4ha1) 18452(P4ha2) 320452(P4ha3)
RNO: 
360526(P4ha2) 361612(P4ha3) 64475(P4ha1)
CGE: 
100757890(P4ha1) 100760683(P4ha2) 100766769(P4ha3)
HGL: 
101702867(P4ha1) 101711128(P4ha3) 101724121(P4ha2)
TUP: 
102482017(P4HA3) 102488136(P4HA1) 102497816(P4HA2)
CFA: 
474672(P4HA2) 479242(P4HA1) 609381(P4HA3)
AML: 
100479558 100480425(P4HA1) 100480972(P4HA2)
FCA: 
101081160(P4HA3) 101094394(P4HA2) 101096846(P4HA1)
PTG: 
102954449(P4HA3) 102964926(P4HA2) 102968339(P4HA1)
BTA: 
414348(P4HA3) 507327(P4HA2) 518288(P4HA1)
BOM: 
102274070(P4HA1) 102274248(P4HA2) 102280992(P4HA3)
PHD: 
102333228(P4HA1) 102335098(P4HA3) 102339818(P4HA2)
CHX: 
102179448(P4HA1) 102186234(P4HA3) 102189116(P4HA2)
SSC: 
100037299(P4HA1) 100623801(P4HA2) 100624543(P4HA3)
CFR: 
102510786(P4HA1) 102516186(P4HA3) 102522559(P4HA2)
BACU: 
102997313 103004544(P4HA1) 103005873(P4HA2) 103012665(P4HA3)
LVE: 
103069084(P4HA1) 103072346(P4HA3) 103089373(P4HA2)
ECB: 
100063760(P4HA1) 100065260(P4HA3) 100072882
MYB: 
102239530 102242052(P4HA2) 102245712(P4HA3) 102255473(P4HA1)
MYD: 
102767574(P4HA2) 102771133(P4HA3) 102775235(P4HA1)
PALE: 
102882040(P4HA3) 102885589(P4HA1) 102892298(P4HA2)
MDO: 
100010507(P4HA1) 100013447(P4HA3) 100018258(P4HA2)
SHR: 
100913891 100921246(P4HA3) 100922527 100931276(P4HA2)
OAA: 
100077226(P4HA1) 100079170(P4HA2)
GGA: 
416326(P4HA2) 419057(P4HA3) 423704(P4HA1)
MGP: 
100544911 100547385 100550944
TGU: 
100223373(P4HA3) 100226743(P4HA2) 100228350(P4HA1)
FAB: 
101807615(P4HA3) 101808225 101809059(P4HA1)
PHI: 
102110972(P4HA3) 102113563(P4HA2) 102114022(P4HA1)
APLA: 
101792390(P4HA2) 101799325(P4HA3) 101802328(P4HA1)
FPG: 
101913115(P4HA2) 101915502(P4HA1) 101921488(P4HA3)
FCH: 
102047744(P4HA2) 102052133(P4HA1) 102054422(P4HA3)
CLV: 
102092707(P4HA3) 102096249(P4HA1) 102096911(P4HA2)
ASN: 
102370647(P4HA3) 102373565(P4HA2) 102376142(P4HA1)
AMJ: 
102557660(P4HA1) 102562067(P4HA2) 102569283(P4HA3)
PSS: 
102449785(P4HA1) 102451448(P4HA2) 102458696(P4HA3)
CMY: 
102932371(P4HA1) 102933622(P4HA2) 102935870(P4HA3)
ACS: 
100565232 100567447
PBI: 
103059803(P4HA1) 103063211 103066775(P4HA3)
XLA: 
447527(p4ha2)
XTR: 
100490484 100492280(p4ha1) 100495824 493342(p4ha2)
DRE: 
100003675(p4ha1b) 373132(p4ha2) 556879 562774(p4ha1a) 563281(p4ha3)
TRU: 
101064031 101066030 101071700 101075755
MZE: 
101464180 101464219 101485561 101486537
OLA: 
101161986 101163841 101166436 101172363
XMA: 
102216605 102219518 102220364 102224850
LCM: 
102346232(P4HA2) 102360424(P4HA3) 102363342(P4HA1)
CMK: 
103177143(p4ha3) 103181221(p4ha1) 103184118(p4ha2)
BFO: 
BRAFLDRAFT_117983 BRAFLDRAFT_204780 BRAFLDRAFT_214927 BRAFLDRAFT_235878 BRAFLDRAFT_261183 BRAFLDRAFT_59428 BRAFLDRAFT_69667 BRAFLDRAFT_84679
CIN: 
100180859 100182956 100184843 100185314
SPU: 
592929
DME: 
Dmel_CG11828 Dmel_CG1546(PH4alphaSG2) Dmel_CG15539 Dmel_CG18749 Dmel_CG31014(PH4alphaSG1) Dmel_CG31015(PH4alphaPV) Dmel_CG31016 Dmel_CG31017(PH4alphaNE3) Dmel_CG31022(PH4alphaEFB) Dmel_CG31524 Dmel_CG32199 Dmel_CG32201 Dmel_CG34345 Dmel_CG4174 Dmel_CG9698 Dmel_CG9720(PH4alphaNE2) Dmel_CG9726(PH4alphaMP) Dmel_CG9728(PH4alphaNE1)
DPO: 
Dpse_GA13747 Dpse_GA15938 Dpse_GA15939 Dpse_GA15946 Dpse_GA21971 Dpse_GA21989 Dpse_GA21991 Dpse_GA26861 Dpse_GA26871 Dpse_GA26875
DAN: 
Dana_GF10815 Dana_GF10816 Dana_GF14452 Dana_GF22904 Dana_GF22906 Dana_GF22908 Dana_GF22909 Dana_GF22917 Dana_GF23245 Dana_GF23317 Dana_GF23318 Dana_GF23326 Dana_GF23328 Dana_GF23330 Dana_GF23331 Dana_GF23629 Dana_GF23630 Dana_GF23631
DER: 
Dere_GG11627 Dere_GG11753 Dere_GG11755 Dere_GG11756 Dere_GG11758 Dere_GG11766 Dere_GG11767 Dere_GG11918 Dere_GG11919 Dere_GG11927 Dere_GG11928 Dere_GG11929 Dere_GG11931 Dere_GG11932 Dere_GG13664 Dere_GG13666 Dere_GG15736
DPE: 
Dper_GL13463 Dper_GL13464 Dper_GL13465 Dper_GL13468 Dper_GL13469 Dper_GL13471 Dper_GL13472 Dper_GL13506 Dper_GL13507 Dper_GL13509 Dper_GL13510 Dper_GL13994 Dper_GL13996 Dper_GL14001 Dper_GL14040 Dper_GL14042 Dper_GL14044 Dper_GL22881 Dper_GL22882 Dper_GL24183 Dper_GL24185 Dper_GL24244 Dper_GL25581
DSE: 
Dsec_GM12139 Dsec_GM12140 Dsec_GM12146 Dsec_GM12148 Dsec_GM12149 Dsec_GM12151 Dsec_GM12152 Dsec_GM12749 Dsec_GM12882 Dsec_GM12884 Dsec_GM12885 Dsec_GM12888 Dsec_GM12897 Dsec_GM12898 Dsec_GM14934 Dsec_GM14980 Dsec_GM14981 Dsec_GM16188 Dsec_GM23710
DSI: 
Dsim_GD12338 Dsim_GD14757 Dsim_GD14758 Dsim_GD16902 Dsim_GD16913 Dsim_GD16980 Dsim_GD16991 Dsim_GD17002 Dsim_GD17024 Dsim_GD17035 Dsim_GD18523 Dsim_GD18524 Dsim_GD21390 Dsim_GD21521 Dsim_GD21523 Dsim_GD21524 Dsim_GD21527 Dsim_GD21536 Dsim_GD21537 Dsim_GD23422
DWI: 
Dwil_GK10713 Dwil_GK11220 Dwil_GK11733 Dwil_GK13116 Dwil_GK13117 Dwil_GK13123 Dwil_GK13124 Dwil_GK13125 Dwil_GK14136 Dwil_GK14137 Dwil_GK14138 Dwil_GK14139 Dwil_GK14140 Dwil_GK14141 Dwil_GK14148 Dwil_GK14149 Dwil_GK24258
DYA: 
Dyak_GE10881 Dyak_GE10884 Dyak_GE10885 Dyak_GE10887 Dyak_GE10893 Dyak_GE10895 Dyak_GE14021 Dyak_GE19962 Dyak_GE22068 Dyak_GE23368 Dyak_GE23369 Dyak_GE23370 Dyak_GE23378 Dyak_GE23379 Dyak_GE23380 Dyak_GE23382 Dyak_GE23383 Dyak_GE23815
DGR: 
Dgri_GH12091 Dgri_GH12975 Dgri_GH12976 Dgri_GH12977 Dgri_GH12978 Dgri_GH12979 Dgri_GH14105 Dgri_GH14106 Dgri_GH14110 Dgri_GH14121 Dgri_GH14132 Dgri_GH14207 Dgri_GH17425 Dgri_GH17427 Dgri_GH17428 Dgri_GH23597
DMO: 
Dmoj_GI10637 Dmoj_GI10638 Dmoj_GI10646 Dmoj_GI13593 Dmoj_GI13596 Dmoj_GI13597 Dmoj_GI22113 Dmoj_GI22114 Dmoj_GI22115 Dmoj_GI22754 Dmoj_GI22756 Dmoj_GI22757 Dmoj_GI23043 Dmoj_GI24860 Dmoj_GI24861 Dmoj_GI24862
DVI: 
Dvir_GJ13932 Dvir_GJ13934 Dvir_GJ22755 Dvir_GJ22757 Dvir_GJ22759 Dvir_GJ22993 Dvir_GJ22994 Dvir_GJ22995 Dvir_GJ23004 Dvir_GJ24233 Dvir_GJ24502 Dvir_GJ24503 Dvir_GJ24504 Dvir_GJ24631
AGA: 
AgaP_AGAP000971 AgaP_AGAP004611
AAG: 
AaeL_AAEL005714 AaeL_AAEL007032 AaeL_AAEL007038
CQU: 
CpipJ_CPIJ017127 CpipJ_CPIJ017129 CpipJ_CPIJ017131
AME: 
408862(PH4alphaEFB)
NVI: 
100116138
TCA: 
657862 657945
BMOR: 
692683
API: 
100158825 100161929 100165503 100166186 100168835 100568765 100575435
PHU: 
Phum_PHUM445570
ISC: 
IscW_ISCW001202 IscW_ISCW001441 IscW_ISCW002014 IscW_ISCW004215 IscW_ISCW006343 IscW_ISCW006859 IscW_ISCW008423 IscW_ISCW008425 IscW_ISCW008426 IscW_ISCW011241 IscW_ISCW011242 IscW_ISCW013602 IscW_ISCW014462 IscW_ISCW015769 IscW_ISCW015771
CEL: 
CELE_F35G2.4(phy-2) CELE_Y47D3B.10(dpy-18)
CBR: 
CBG06252(Cbr-phy-2) CBG13195(Cbr-dpy-18)
BMY: 
Bm1_45455
LOA: 
LOAG_06927 LOAG_11701
TSP: 
Tsp_03346 Tsp_03348 Tsp_13511 Tsp_15957
SMM: 
Smp_068280
NVE: 
NEMVE_v1g120212 NEMVE_v1g120225 NEMVE_v1g195205
HMG: 
100207876 100211222 100214656
TAD: 
TRIADDRAFT_30039 TRIADDRAFT_59899
AQU: 
100634548
ATH: 
AT1G20270 AT2G17720 AT2G23096 AT2G43080(AT-P4H-1) AT3G06300(AT-P4H-2) AT3G28480 AT3G28490 AT4G25600 AT4G33910 AT4G35810 AT4G35820 AT5G18900 AT5G66060
ALY: 
ARALYDRAFT_328172 ARALYDRAFT_472257 ARALYDRAFT_480667 ARALYDRAFT_481183 ARALYDRAFT_484624 ARALYDRAFT_488774 ARALYDRAFT_491287 ARALYDRAFT_492267 ARALYDRAFT_497011 ARALYDRAFT_656411 ARALYDRAFT_664704 ARALYDRAFT_896741 ARALYDRAFT_903688
CRB: 
CARUB_v10001574mg CARUB_v10005232mg CARUB_v10005407mg CARUB_v10006984mg CARUB_v10007325mg CARUB_v10009921mg CARUB_v10014146mg CARUB_v10014309mg CARUB_v10017667mg CARUB_v10018771mg CARUB_v10023796mg CARUB_v10023900mg CARUB_v10026902mg
EUS: 
EUTSA_v10000619mg EUTSA_v10004627mg EUTSA_v10004714mg EUTSA_v10010038mg EUTSA_v10014223mg EUTSA_v10017046mg EUTSA_v10021226mg EUTSA_v10022796mg EUTSA_v10025829mg EUTSA_v10025904mg EUTSA_v10027274mg
CIT: 
102612484 102613795 102615941 102615950 102618871 102620398 102628340 102628780
CIC: 
CICLE_v10005478mg CICLE_v10005535mg CICLE_v10012224mg CICLE_v10016152mg CICLE_v10021508mg CICLE_v10026208mg CICLE_v10027070mg CICLE_v10028993mg
TCC: 
TCM_000132 TCM_000752 TCM_000753 TCM_007194 TCM_015195 TCM_018081 TCM_020061 TCM_021094 TCM_034293
GMX: 
100527885 100775302 100775928 100776115 100782154 100783075 100794585 100795761 100796794 100798201 100804652 100805097 100806046 100809996 100811068 100811904 100813618 100816628 100818586 100818794 100819289 100820384 100820606
PVU: 
PHAVU_002G013200g PHAVU_002G104900g PHAVU_003G098900g PHAVU_003G267200g PHAVU_004G024300g PHAVU_004G113700g PHAVU_006G159200g PHAVU_007G002000g PHAVU_007G043100g PHAVU_009G019600g
MTR: 
MTR_1g116810 MTR_2g020800 MTR_2g089830 MTR_3g051200 MTR_3g114590 MTR_3g114610 MTR_3g114670 MTR_4g095370 MTR_4g118560 MTR_5g016090 MTR_5g022960 MTR_6g009440 MTR_8g074810 MTR_8g074830 MTR_8g074870 MTR_8g074880 MTR_8g074890
CAM: 
101488382 101496423 101500815 101501139 101502651 101503898 101504842 101505164 101510244 101511375 101512678
FVE: 
101297607 101303432 101306377 101310176 101312187 101312625 101312789 101312919
PPER: 
PRUPE_ppa008787mg PRUPE_ppa009336mg PRUPE_ppa009459mg PRUPE_ppa009475mg PRUPE_ppa009548mg PRUPE_ppa010789mg PRUPE_ppa023428mg PRUPE_ppa024698mg
CSV: 
101204265 101206818 101209446 101210382 101215570 101217481 101218099 101218235 101218968 101221376 101221643 101226178 101229258 101231596 101231616
RCU: 
RCOM_0174710 RCOM_0396560 RCOM_0679070 RCOM_0782750 RCOM_0853250 RCOM_0998510 RCOM_1583270 RCOM_1599420
POP: 
POPTR_0001s30400g(POPTRDRAFT_707400) POPTR_0002s01820g POPTR_0002s23310g(POPTRDRAFT_830522) POPTR_0005s10980g POPTR_0005s26660g(POPTRDRAFT_801579) POPTR_0007s09270g POPTR_0007s10120g POPTR_0008s20230g(POPTRDRAFT_1085714) POPTR_0009s09420g(POPTRDRAFT_1087308) POPTR_0010s02790g(POPTRDRAFT_657945) POPTR_0012s13040g(POPTRDRAFT_570439) POPTR_0017s11150g(POPTRDRAFT_1105096) POPTR_0017s11170g(POPTRDRAFT_908378)
VVI: 
100241153 100242241 100244673 100245913 100252283 100252286 100254198 100256084 100266991
SLY: 
101244118 101244153 101245118 101246711 101249044 101254254 101255367 101259696 101262682 101265933 101267095
SOT: 
102578911 102579923 102580816 102581670 102587844 102591537 102591988 102593414 102596044 102599198 102603525 102604428 102605813
OSA: 
4327127 4334196 4334477 4335530 4339155 4342642 4348615 4349012 9270970
DOSA: 
Os01t0174500-01(Os01g0174500) Os03t0166100-00(Os03g0166100) Os03t0166200-00(Os03g0166200) Os03t0761900-01(Os03g0761900) Os03t0803500-01(Os03g0803500) Os04t0346000-01(Os04g0346000) Os05t0489100-01(Os05g0489100) Os07t0194500-01(Os07g0194500) Os10t0413500-01(Os10g0413500) Os10t0497800-01(Os10g0497800)
OBR: 
102701810 102707313 102707558 102708137 102711192 102712665 102715334 102715407 102717418 102717693 102719094
BDI: 
100830921 100831521 100832458 100832694 100834813 100835020 100835342 100843006
SBI: 
SORBI_01g004670(SORBIDRAFT_01g004670) SORBI_01g007280(SORBIDRAFT_01g007280) SORBI_01g018200(SORBIDRAFT_01g018200) SORBI_01g022150(SORBIDRAFT_01g022150) SORBI_02g005750(SORBIDRAFT_02g005750) SORBI_02g005760(SORBIDRAFT_02g005760) SORBI_03g004265(SORBIDRAFT_03g004265) SORBI_04g038020(SORBIDRAFT_04g038020) SORBI_06g004550(SORBIDRAFT_06g004550) SORBI_08g016950(SORBIDRAFT_08g016950) SORBI_09g023860(SORBIDRAFT_09g023860)
ZMA: 
100193348 100193935(pco071536) 100274058 100282945(pco107217) 100283657(cl32377_1(260)) 100284871(pco093706) 100303994 100383727 100857079(P4H2-1) 100857080(P4H4) 100857081(P4H4-2) 100857082(P4H5-1) 100857083(P4H6) 100857087(P4H6-3) 100857088(P4H8-2) 100857089(P4H8-3) 100857090(P4H8-4) 100857091(P4H8-5)
SITA: 
101753221 101757367 101759577 101769812 101775858 101777428 101779189 101780014 101783088
ATR: 
s00001p00155640(AMTR_s00001p00155640) s00005p00135530(AMTR_s00005p00135530) s00019p00257460(AMTR_s00019p00257460) s00081p00029310(AMTR_s00081p00029310) s00098p00019020(AMTR_s00098p00019020) s00098p00020560(AMTR_s00098p00020560) s00144p00069890(AMTR_s00144p00069890)
SMO: 
SELMODRAFT_106693 SELMODRAFT_129912 SELMODRAFT_174666 SELMODRAFT_234144 SELMODRAFT_411114 SELMODRAFT_418273 SELMODRAFT_431327 SELMODRAFT_67344 SELMODRAFT_82355 SELMODRAFT_84512 SELMODRAFT_86017
PPP: 
PHYPADRAFT_115022 PHYPADRAFT_16503 PHYPADRAFT_168322 PHYPADRAFT_202199 PHYPADRAFT_5584 PHYPADRAFT_68659
CRE: 
CHLREDRAFT_111255 CHLREDRAFT_111407 CHLREDRAFT_111555 CHLREDRAFT_114525 CHLREDRAFT_122372 CHLREDRAFT_138462(PHX1) CHLREDRAFT_138508 CHLREDRAFT_143143 CHLREDRAFT_143800 CHLREDRAFT_166317 CHLREDRAFT_187378 CHLREDRAFT_190697 CHLREDRAFT_79261 CHLREDRAFT_96954
VCN: 
VOLCADRAFT_106018 VOLCADRAFT_120451 VOLCADRAFT_121183 VOLCADRAFT_60971 VOLCADRAFT_62820 VOLCADRAFT_63898 VOLCADRAFT_64430 VOLCADRAFT_64439 VOLCADRAFT_67269 VOLCADRAFT_72865 VOLCADRAFT_80309 VOLCADRAFT_81799 VOLCADRAFT_82641 VOLCADRAFT_89416
OLU: 
OSTLU_37102 OSTLU_37480 OSTLU_42939 OSTLU_6080 OSTLU_6831 OSTLU_87339
OTA: 
Ot01g03290 Ot01g04940 Ot02g07180 Ot04g00140(P4HA1) Ot05g03500 Ot15g02310
MIS: 
MICPUN_102832 MICPUN_105075 MICPUN_55182 MICPUN_62720 MICPUN_70761 MICPUN_70768 MICPUN_71136 MICPUN_71386
MPP: 
MICPUCDRAFT_15413 MICPUCDRAFT_18183 MICPUCDRAFT_34636 MICPUCDRAFT_35463 MICPUCDRAFT_49069 MICPUCDRAFT_5312
BPG: 
Bathy01g00420 Bathy02g00700 Bathy03g04350 Bathy05g04830 Bathy12g01950 Bathy15g01110
CSL: 
COCSUDRAFT_25518 COCSUDRAFT_35772 COCSUDRAFT_40745 COCSUDRAFT_47131 COCSUDRAFT_53414 COCSUDRAFT_57307
CVR: 
CHLNCDRAFT_135671 CHLNCDRAFT_137600 CHLNCDRAFT_141231 CHLNCDRAFT_142031 CHLNCDRAFT_143796 CHLNCDRAFT_143806 CHLNCDRAFT_19485 CHLNCDRAFT_28161 CHLNCDRAFT_28187 CHLNCDRAFT_35843 CHLNCDRAFT_49444
NCR: 
NCU00207
SMP: 
SMAC_01409 SMAC_05290
PAN: 
PODANSg09799 PODANSg1073 PODANSg4791 PODANSg6886
TTT: 
THITE_2055322 THITE_2118894 THITE_2145661
MTM: 
MYCTH_2051636 MYCTH_2060641
CTHR: 
CTHT_0055490
MGR: 
MGG_06278
FGR: 
FG05473.1
NHE: 
NECHADRAFT_71135
TRE: 
TRIREDRAFT_107360 TRIREDRAFT_66047
MAJ: 
MAA_10531
CMT: 
CCM_06081
VAL: 
VDBG_09816
ELA: 
UCREL1_3445 UCREL1_8240
SSL: 
SS1G_08912
BFU: 
BC1G_10940
MBE: 
MBM_08740 MBM_08897
ANI: 
AN2851.2
AFM: 
AFUA_3G11980
AOR: 
AOR_1_1350154(AO090003000761)
ANG: 
ANI_1_2732024(An02g07870)
AFV: 
AFLA_030540
ACT: 
ACLA_039860 ACLA_063290
NFI: 
NFIA_065320
PCS: 
Pc18g00410
CIM: 
CIMG_09826
CPW: 
CPC735_022610
PNO: 
SNOG_03610 SNOG_05086 SNOG_06400
PTE: 
PTT_06584
BZE: 
COCCADRAFT_2164
ZTR: 
MYCGRDRAFT_33455
PFJ: 
MYCFIDRAFT_142999 MYCFIDRAFT_26183
BCOM: 
BAUCODRAFT_144379
MBR: 
MONBRDRAFT_23906 MONBRDRAFT_37507
DDI: 
DDB_G0275385
DPP: 
DICPUDRAFT_151895
DFA: 
DFA_03579
TAN: 
TA04445
BEQ: 
BEWA_013750
TGO: 
TGME49_021270
PTI: 
PHATRDRAFT_13557 PHATRDRAFT_38694 PHATRDRAFT_48891 PHATRDRAFT_4950 PHATRDRAFT_5156 PHATRDRAFT_55162 PHATR_10655
TPS: 
THAPSDRAFT_18190 THAPSDRAFT_24375 THAPSDRAFT_24377 THAPSDRAFT_262637 THAPSDRAFT_263006 THAPSDRAFT_264010 THAPSDRAFT_264177 THAPSDRAFT_4571 THAPSDRAFT_5584 THAPSDRAFT_6480 THAPSDRAFT_8415 THAPSDRAFT_9519 THAPS_10787 THAPS_38110
PIF: 
PITG_04973 PITG_11705 PITG_19004
NGD: 
NGA_2013900
EHX: 
EMIHUDRAFT_101851 EMIHUDRAFT_103230 EMIHUDRAFT_117677 EMIHUDRAFT_119786 EMIHUDRAFT_218427 EMIHUDRAFT_222190 EMIHUDRAFT_222496 EMIHUDRAFT_229551 EMIHUDRAFT_236216 EMIHUDRAFT_350663 EMIHUDRAFT_367381 EMIHUDRAFT_423042 EMIHUDRAFT_424641 EMIHUDRAFT_431953 EMIHUDRAFT_435815 EMIHUDRAFT_439880 EMIHUDRAFT_440074 EMIHUDRAFT_440940 EMIHUDRAFT_442666 EMIHUDRAFT_442781 EMIHUDRAFT_450878 EMIHUDRAFT_452700 EMIHUDRAFT_457325 EMIHUDRAFT_459487 EMIHUDRAFT_465463 EMIHUDRAFT_466417 EMIHUDRAFT_468503 EMIHUDRAFT_55595 EMIHUDRAFT_55676 EMIHUDRAFT_56349 EMIHUDRAFT_62208 EMIHUDRAFT_65594 EMIHUDRAFT_65934 EMIHUDRAFT_70930 EMIHUDRAFT_77912 EMIHUDRAFT_78042 EMIHUDRAFT_99259
GTT: 
GUITHDRAFT_112917 GUITHDRAFT_114401 GUITHDRAFT_150687 GUITHDRAFT_152114 GUITHDRAFT_44480 GUITHDRAFT_71994 GUITHDRAFT_84780 GUITHDRAFT_92735
XCC: 
XCC3429
XCB: 
XC_0735
XCP: 
XCR_3769
XCV: 
XCV0752
XAC: 
XAC0691
XCI: 
XCAW_03890
XAX: 
XACM_0696
XAO: 
XAC29_03515
XFU: 
XFF4834R_chr07000
PSU: 
Psesu_0952
PSD: 
DSC_10945
RHD: 
R2APBS1_0370
DJI: 
CH75_22515
PRW: 
PsycPRwf_1859
SDE: 
Sde_3273 Sde_3700
AMC: 
MADE_1006225
AMAC: 
MASE_03040 MASE_05190
AMB: 
AMBAS45_03290
AMG: 
AMEC673_03255 AMEC673_05270
AMH: 
I633_05910
AMK: 
AMBLS11_03220 AMBLS11_05295
AMAA: 
amad1_05610
AMAL: 
I607_05385
AMAE: 
I876_05675
AMAO: 
I634_05700
AMAD: 
I636_05620
AMAI: 
I635_05585
AMAG: 
I533_05275
ALT: 
ambt_12960 ambt_14915
MMT: 
Metme_0168
TKM: 
TK90_2795
AFE: 
Lferr_2737
AFR: 
AFE_1210
AFI: 
Acife_1859
SAGA: 
M5M_16075
RSO: 
RSc2814
RSC: 
RCFBP_10646
RSL: 
RPSI07_0693
RSN: 
RSPO_c00694
RSM: 
CMR15_10601
RSE: 
F504_2741
RPI: 
Rpic_3059
RPF: 
Rpic12D_2649
REU: 
Reut_A2950
REH: 
H16_A3244(phy)
CNC: 
CNE_1c31800(phy)
RME: 
Rmet_3098
CTI: 
RALTA_A2697
BXE: 
Bxe_B0348 Bxe_B1199
BPH: 
Bphy_5329
BPY: 
Bphyt_5409
BUG: 
BC1001_3722
BGE: 
BC1002_3991 BC1002_4858
BGF: 
BC1003_3769
BGD: 
bgla_2g25050
BYI: 
BYI23_D000440 BYI23_D012160
BPX: 
BUPH_00288
POL: 
Bpro_3712
AAV: 
Aave_1171
AJS: 
Ajs_3293
DIA: 
Dtpsy_2646
AAA: 
Acav_1184
ACK: 
C380_07130
DAC: 
Daci_5284
DEL: 
DelCs14_1329
VAP: 
Vapar_1302 Vapar_3584
VPE: 
Varpa_1403 Varpa_4544
VPD: 
VAPA_1c13750 VAPA_1c37020
CTT: 
CtCNB1_0958
ADN: 
Alide_3198
ADK: 
Alide2_1249
RTA: 
Rta_28970
MPT: 
Mpe_A2091
CFU: 
CFU_2670
LCH: 
Lcho_2651
RGE: 
RGE_13160
BBT: 
BBta_1313
HNE: 
HNE_1861
NAR: 
Saro_1382
NPP: 
PP1Y_AT14227
SAL: 
Sala_1522
SWI: 
Swit_2573
SJP: 
SJA_C1-32480
SCH: 
Sphch_0026
SSY: 
SLG_08240 SLG_13730
ELI: 
ELI_02985 ELI_03845
BAN: 
BA_4459
BAR: 
GBAA_4459
BAT: 
BAS4138
BAH: 
BAMEG_4493
BAI: 
BAA_4476
BAX: 
H9401_4253
BANT: 
A16_44550
BANR: 
A16R_45100
BAL: 
BACI_c42010
BCE: 
BC4233
BCA: 
BCE_4314
BCZ: 
BCZK3988
BCR: 
BCAH187_A4367
BCB: 
BCB4264_A4348
BCU: 
BCAH820_4256
BCG: 
BCG9842_B0892
BCQ: 
BCQ_4020
BCX: 
BCA_4345
BNC: 
BCN_4148
BCF: 
bcf_21065
BCER: 
BCK_13995
BTK: 
BT9727_3978
BTL: 
BALH_3835
BTB: 
BMB171_C3904
BTT: 
HD73_4540
BTC: 
CT43_CH4249
BTF: 
YBT020_20895
BTM: 
MC28_3528
BTG: 
BTB_c43770
BTI: 
BTG_28220
BTN: 
BTF1_19550
BTHT: 
H175_ch4319
BTHU: 
YBT1518_23380
BWE: 
BcerKBAB4_4090
BTY: 
Btoyo_1479
BMQ: 
BMQ_2841
BMD: 
BMD_2875
BMH: 
BMWSH_2348
BCO: 
Bcell_0583
BIF: 
N288_14065
HHD: 
HBHAL_1453
BBE: 
BBR47_52080
PJD: 
Pjdr2_0570
TCO: 
Theco_3434
SIV: 
SSIL_1645
AYM: 
YM304_21960
SYW: 
SYNW2355
SYD: 
Syncc9605_2496
SYE: 
Syncc9902_2168
HAO: 
PCC7418_0240
 » show all
Taxonomy
Reference
1  [PMID:4346946]
  Authors
Berg RA, Prockop DJ.
  Title
Affinity column purification of protocollagen proline hydroxylase from chick embryos and further characterization of the enzyme.
  Journal
J. Biol. Chem. 248 (1973) 1175-82.
  Organism
Rattus norvegicus
Reference
2
  Authors
Hutton, J.J., Jr., Tappel, A.L. and Udenfriend, S.
  Title
Cofactor and substrate requirements of collagen proline hydroxylase.
  Journal
Arch. Biochem. Biophys. 118 (1967) 231-240.
Reference
3  [PMID:5046811]
  Authors
Kivirikko KI, Kishida Y, Sakakibara S, Prockop DJ.
  Title
Hydroxylation of (X-Pro-Gly)n by protocollagen proline hydroxylase. Effect of chain length, helical conformation and amino acid sequence in the substrate.
  Journal
Biochim. Biophys. Acta. 271 (1972) 347-56.
  Organism
Rattus norvegicus, Gallus gallus
Reference
4
  Authors
Kivirikko, K.I. and Prockop, D.J.
  Title
Purification and partial characterization of the enzyme for the hydroxylation of proline in protocollogen.
  Journal
Arch. Biochem. Biophys. 118 (1967) 611-618.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-06-2
DBGET integrated database retrieval system