KEGG   ENZYME: 1.14.19.2Help
Entry
EC 1.14.19.2                Enzyme                                 
Name
acyl-[acyl-carrier-protein] desaturase;
stearyl acyl carrier protein desaturase;
stearyl-ACP desaturase;
acyl-[acyl-carrier-protein], hydrogen-donor:oxygen oxidoreductase
Class
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
BRITE hierarchy
Sysname
acyl-[acyl-carrier protein],hydrogen-donor:oxygen oxidoreductase
Reaction(IUBMB)
a stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = an oleoyl-[acyl-carrier protein] + acceptor + 2 H2O [RN:R03370]
Reaction(KEGG)
R03370;
(other) R08161
Show
Substrate
stearoyl-[acyl-carrier protein] [CPD:C04088];
reduced acceptor [CPD:C00030];
O2 [CPD:C00007]
Product
oleoyl-[acyl-carrier protein] [CPD:C01203];
acceptor [CPD:C00028];
H2O [CPD:C00001]
Comment
The enzyme from safflower is specific for stearoyl-[acyl-carrier protein]; that from Euglena acts on derivatives of a number of long-chain fatty acids. Requires ferredoxin.
Pathway
Fatty acid biosynthesis
Biosynthesis of unsaturated fatty acids
Orthology
K03921  
acyl-[acyl-carrier-protein] desaturase
K03922  
acyl-[acyl-carrier-protein] desaturase
Genes
ATH: 
ALY: 
GMX: 
100037478(SACPD-C) 100217331(SAD2)
MTR: 
CSV: 
RCU: 
POP: 
VVI: 
OSA: 
DOSA: 
Os01t0880800-01(Os01g0880800) Os01t0919900-01(Os01g0919900) Os02t0504800-01(Os02g0504800) Os03t0423300-01(Os03g0423300) Os04t0379900-01(Os04g0379900) Os08t0199400-01(Os08g0199400) Os08t0200100-01(Os08g0200100)
BDI: 
100827641 100828511 100829329 100830577 100846588 100846692
SBI: 
SORBI_01g025880(SORBIDRAFT_01g025880) SORBI_01g032300(SORBIDRAFT_01g032300) SORBI_02g029360(SORBIDRAFT_02g029360) SORBI_03g041700(SORBIDRAFT_03g041700) SORBI_03g043970(SORBIDRAFT_03g043970) SORBI_04g020500(SORBIDRAFT_04g020500) SORBI_06g012520(SORBIDRAFT_06g012520) SORBI_07g005670(SORBIDRAFT_07g005670) SORBI_10g027710(SORBIDRAFT_10g027710)
ZMA: 
100191672(gpm375a) 100192652(cl3036_1) 100194244 100272745 100273826(cl27608_1) 100283843(csu333) 100284715 100284776 100284973 100382139
SMO: 
SELMODRAFT_231587 SELMODRAFT_233160 SELMODRAFT_272030 SELMODRAFT_411132
PPP: 
PHYPADRAFT_100583 PHYPADRAFT_110588 PHYPADRAFT_153909 PHYPADRAFT_232858 PHYPADRAFT_85372 PHYPADRAFT_87393 PHYPADRAFT_89338
CRE: 
CHLREDRAFT_205753(FAB2)
VCN: 
VOLCADRAFT_109049
OLU: 
OSTLU_15111
OTA: 
Ot04g03720
PTI: 
PHATRDRAFT_9316
TPS: 
THAPSDRAFT_bd1192(DES7)
SCL: 
sce2527
BCZ: 
BCZK2881(staD)
BCG: 
BCG9842_B2162
BTI: 
BTG_03995
BTN: 
BTF1_10455
BTHT: 
H175_328p150
BWE: 
BcerKBAB4_1064
BACI: 
B1NLA3E_11075
ESI: 
Exig_2392
EAN: 
Eab7_2235
PMS: 
KNP414_00297
PMQ: 
PM3016_254
PMW: 
B2K_01300
BTS: 
Btus_3008
SAY: 
TPY_2839
SAP: 
Sulac_1047
MTU: 
Rv0824c(desA1) Rv1094(desA2)
MTV: 
RVBD_0824c RVBD_1094
MTC: 
MT0846 MT1126
MRA: 
MRA_0834(desA1) MRA_1105(desA2)
MTF: 
TBFG_10839 TBFG_11115
MTB: 
TBMG_00838 TBMG_02890
MTK: 
TBSG_00844 TBSG_02906
MTZ: 
TBXG_000831 TBXG_002870
MTG: 
MRGA327_05170 MRGA327_06850
MTI: 
MRGA423_05170 MRGA423_06850
MTE: 
CCDC5079_0761 CCDC5079_1010
MTL: 
CCDC5180_0753 CCDC5180_1002
MTO: 
MTCTRI2_0841(desA1) MTCTRI2_1124(desA2)
MTD: 
UDA_0824c(desA1) UDA_1094(desA2)
MTN: 
ERDMAN_0907(desA1) ERDMAN_1226(desA2)
MTJ: 
J112_04425 J112_05910
MTUB: 
MT7199_0843 MT7199_1121
MBO: 
Mb0847c(desA1) Mb1124(desA2)
MBB: 
BCG_0877c(desA1) BCG_1154(desA2)
MBT: 
JTY_0847(desA1) JTY_1127(desA2)
MBM: 
BCGMEX_0848c(desA1) BCGMEX_1126(desA2)
MBK: 
K60_008780 K60_011790
MAF: 
MAF_08340(desA1) MAF_11090(desA2)
MCE: 
MCAN_08271(desA1) MCAN_11031(desA2)
MCQ: 
BN44_10898(desA) BN44_11218(desA)
MCV: 
BN43_20267(desA) BN43_30150(desA)
MCX: 
BN42_20586(desA) BN42_20941(desA)
MCZ: 
BN45_20093(desA) BN45_30136(desA)
MLE: 
ML1952(desA2) ML2185(desA1)
MLB: 
MLBr_01952(desA2) MLBr_02185(desA1)
MPA: 
MAP0658c(desA1) MAP2698c(desA2)
MAV: 
MAV_0772 MAV_1216 MAV_1793
MIT: 
OCO_06740 OCO_11220
MIR: 
OCQ_06900 OCQ_11230
MIA: 
OCU_06800 OCU_11200
MID: 
MIP_01188 MIP_01807
MSM: 
MSMEG_5248 MSMEG_5773
MSG: 
MSMEI_5110(desA2) MSMEI_5619(des)
MSA: 
Mycsm_02132 Mycsm_05066 Mycsm_05596
MUL: 
MUL_0187(desA2) MUL_0445(desA1) MUL_3646(desA1_1)
MVA: 
Mvan_4653 Mvan_5085 Mvan_5927
MGI: 
Mflv_1668 Mflv_2061
MSP: 
Mspyr1_10450 Mspyr1_14850
MAB: 
MAB_0754c MAB_1237 MAB_2157 MAB_2550c MAB_3354 MAB_4403c
MMV: 
MYCMA_0401(desA1) MYCMA_0664(desA2) MYCMA_1137(desA1) MYCMA_1376(desA1) MYCMA_1850(desA1) MYCMA_2444(desA1)
MMC: 
Mmcs_4130 Mmcs_4511 Mmcs_4940
MKM: 
Mkms_4205 Mkms_4598 Mkms_5028
MJL: 
Mjls_4361 Mjls_4894 Mjls_5321
MJD: 
JDM601_0873(desA1_1) JDM601_1040(desA2) JDM601_3526(desA1)
MMI: 
MMAR_3704(desA1_1) MMAR_4374(desA2) MMAR_4856(desA1)
MRH: 
MycrhN_2577 MycrhN_3534 MycrhN_6042
MMM: 
W7S_03315 W7S_05485
MCB: 
Mycch_4067 Mycch_4457
MLI: 
MULP_03954(desA1_1) MULP_04589(desA2_1) MULP_05089(desA1)
NFA: 
nfa6080
NCY: 
NOCYR_0619 NOCYR_1638
NBR: 
O3I_003425 O3I_020015 O3I_022675 O3I_029895
RHA: 
RHA1_ro02258 RHA1_ro04869
RER: 
RER_47900(desA1)
ROP: 
ROP_49510(desA1)
REQ: 
REQ_08730
GBR: 
Gbro_1946 Gbro_2141 Gbro_3918
GPO: 
GPOL_c20390 GPOL_c40440
GOR: 
KTR9_2066 KTR9_3848
TPR: 
Tpau_3535 Tpau_3536
SRT: 
Srot_0112 Srot_0250 Srot_2592
SCO: 
SCO6717(SC4C6.27c)
SMA: 
SAV_1691
SGR: 
SGR_1008
SCB: 
SCAB_13461
SSX: 
SACTE_5887
SVL: 
Strvi_7936
SFA: 
Sfla_0689
SBH: 
SBI_07084 SBI_07647
SHY: 
SHJG_7615
SHO: 
SHJGH_7376
SVE: 
SVEN_6398
SDV: 
BN159_1702(desA1)
SALB: 
XNR_0316
STRP: 
F750_6176
SFI: 
SFUL_6491
KSK: 
KSE_54350(desA)
KFL: 
Kfla_7030
TCU: 
Tcur_3578
SRO: 
Sros_1903
FRA: 
Francci3_0307
FRE: 
Franean1_6505
FRI: 
FraEuI1c_6811
FAL: 
FRAAL0670
FSY: 
FsymDg_1327
NML: 
Namu_0992
BSD: 
BLASA_4857
MMAR: 
MODMU_5493
AMD: 
AMED_4117
AMN: 
RAM_20980
AMM: 
AMES_4069
STP: 
Strop_1820
SAQ: 
Sare_1811
MAU: 
Micau_2300
MIL: 
ML5_2412
CAI: 
Caci_2173
AYM: 
YM304_36700(desA)
PHE: 
Phep_1163
PSN: 
Pedsa_2278
SHG: 
Sph21_4113
SCN: 
Solca_0014
HHY: 
Halhy_6519
CMR: 
Cycma_1160
BBD: 
Belba_0704
EVI: 
Echvi_0785
DFE: 
Dfer_5690
SLI: 
Slin_4583
LBY: 
Lbys_3166
RSI: 
Runsl_2492
FLI: 
Fleli_0508
EOL: 
Emtol_1909
FAE: 
FAES_2147
GFO: 
GFO_3404
FPS: 
FP0051 FP1155
FBR: 
FBFL15_0290
FCO: 
FCOL_09460
FIN: 
KQS_13090
ZPR: 
ZPR_0309
CAT: 
CA2559_03705
FBC: 
FB2170_06790
CAO: 
Celal_1233
CLY: 
Celly_1131
WVI: 
Weevi_0221
LAN: 
Lacal_1133
ZGA: 
zobellia_1485(ACPD)
MRS: 
Murru_1170
ASL: 
Aeqsu_1101
NDO: 
DDD_1638
POM: 
MED152_09405
FBA: 
FIC_01332
OHO: 
Oweho_0169
GAU: 
GAU_3746
SACI: 
Sinac_1176 Sinac_3608
NOP: 
Nos7524_1354
IAL: 
IALB_0537
HAU: 
Haur_0733
DDR: 
Deide_02410
DMR: 
Deima_1660
DGO: 
DGo_CA2715(staD)
DPD: 
Deipe_2637
TRA: 
Trad_2440
LFC: 
LFE_1098
LFI: 
LFML04_1406 LFML04_1474
 » show all
Taxonomy
Reference
1  [PMID:4831331]
  Authors
Jaworski JG, Stumpf PK.
  Title
Fat metabolism in higher plants. Properties of a soluble stearyl-acyl carrier protein desaturase from maturing Carthamus tinctorius.
  Journal
Arch. Biochem. Biophys. 162 (1974) 158-65.
  Organism
Carthamus tinctorius
Reference
2  [PMID:4300868]
  Authors
Nagai J, Bloch K.
  Title
Enzymatic desaturation of stearyl acyl carrier protein.
  Journal
J. Biol. Chem. 243 (1968) 4626-33.
  Organism
Euglena gracilis
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37256-86-3
DBGET integrated database retrieval system