KEGG   ENZYME: 1.2.1.44Help
Entry
EC 1.2.1.44                 Enzyme                                 

Name
cinnamoyl-CoA reductase;
feruloyl-CoA reductase;
cinnamoyl-coenzyme A reductase;
ferulyl-CoA reductase;
feruloyl coenzyme A reductase;
p-hydroxycinnamoyl coenzyme A reductase;
cinnamoyl-CoA:NADPH reductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)
Reaction(IUBMB)
cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+ [RN:R02506]
Reaction(KEGG)
Substrate
cinnamaldehyde [CPD:C00903];
CoA [CPD:C00010];
NADP+ [CPD:C00006]
Product
cinnamoyl-CoA [CPD:C00540];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Acts also on a number of substituted cinnamoyl esters of coenzyme A.
History
EC 1.2.1.44 created 1978
Pathway
Phenylpropanoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K09753  
cinnamoyl-CoA reductase
Genes
ATH: 
AT1G15950(CCR1) AT1G80820(CCR2)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
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PVU: 
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ADU: 
AIP: 
FVE: 
PPER: 
PMUM: 
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PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
VVI: 
SLY: 
100125904(CCR1) 778359(CCR2)
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4345689 4346438(OJ1352_A10.23) 4347074(CCR)
DOSA: 
Os01t0283600-00(Os01g0283600) Os01t0283700-01(Os01g0283700) Os02t0180700-01(Os02g0180700) Os02t0808800-01(Os02g0808800) Os02t0811400-00(Os02g0811400) Os02t0811600-00(Os02g0811600) Os02t0811800-01(Os02g0811800) Os02t0812000-01(Os02g0812000) Os08t0277200-01(Os08g0277200) Os08t0441500-01(Os08g0441500) Os09t0127300-01(Os09g0127300) Os09t0262000-00(Os09g0262000) Os09t0419200-01(Os09g0419200)
OBR: 
BDI: 
SBI: 
SORBI_02g014910(SORBIDRAFT_02g014910) SORBI_03g011580(SORBIDRAFT_03g011580) SORBI_04g005510(SORBIDRAFT_04g005510) SORBI_04g036770(SORBIDRAFT_04g036770) SORBI_04g036780(SORBIDRAFT_04g036780) SORBI_07g021680(SORBIDRAFT_07g021680) SORBI_10g005700(SORBIDRAFT_10g005700)
ZMA: 
100285564(GRMZM2G057328) 100382657 103634692(GRMZM2G146031) 103634693(GRMZM2G017285) 103654125 542463(cncr1) 542735(cncr2)
SITA: 
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 » show all
Taxonomy
Reference
1  [PMID:236926]
  Authors
Gross GG, Kreiten W.
  Title
Reduction of coenzyme A thioesters of cinnamic acids with an enzyme preparation from lignifying tissue of Forsythia.
  Journal
FEBS. Lett. 54 (1975) 259-62.
Reference
2  [PMID:6365550]
  Authors
Sarni F, Grand C, Boudet AM.
  Title
Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana).
  Journal
Eur. J. Biochem. 139 (1984) 259-65.
Reference
3  [PMID:7454]
  Authors
Wengenmayer H, Ebel J, Grisebach H.
  Title
Enzymic synthesis of lignin precursors. Purification and properties of a cinnamoyl-CoA: NADPH reductase from cell suspension cultures of soybean (Glycinemax).
  Journal
Eur. J. Biochem. 65 (1976) 529-36.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
59929-39-4

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