KEGG   ENZYME: 1.2.1.46Help
Entry
EC 1.2.1.46                 Enzyme                                 
Name formaldehyde dehydrogenase;
NAD+-linked formaldehyde dehydrogenase;
NAD+-dependent formaldehyde dehydrogenase
Class Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname formaldehyde:NAD+ oxidoreductase
Reaction(IUBMB) formaldehyde + NAD+ + H2O = formate + NADH + 2 H+ [RN:R00604]
Reaction(KEGG) R00604
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Substrate formaldehyde [CPD:C00067];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product formate [CPD:C00058];
NADH [CPD:C00004];
H+ [CPD:C00080]
Pathway PATH: ec00680  Methane metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00148  glutathione-independent formaldehyde dehydrogenase
Genes PAE: PA5421(fdhA)
PAU: PA14_71560(fdhA)
PPU: PP_0328(fdhA)
PPF: Pput_0350
PSB: Psyr_4718
PSP: PSPPH_2569(fdhA1) PSPPH_4756(fdhA2)
PFL: PFL_5723(fdhA)
PFO: Pfl01_5202
PEN: PSEEN5156(fdhA)
CPS: CPS_4039
RSO: RSp0053(fdhA)
REU: Reut_B4824
BMA: BMAA0468(fdhA)
BMV: BMASAVP1_0712(fdhA)
BML: BMA10229_1008(fdhA)
BMN: BMA10247_A1981(fdhA)
BPS: BPSS0545(fdhA)
BPM: BURPS1710b_A2104(fdhA)
BPL: BURPS1106A_A0738(fdhA)
BPD: BURPS668_A0826(fdhA)
BTE: BTH_II1870
BVI: Bcep1808_3428
BUR: Bcep18194_B0564
BCH: Bcen2424_5090
BXE: Bxe_B1589(fdsA)
VEI: Veis_3227
HAR: HEAR2048(fdhA)
ATU: Atu1567(fdhA)
RET: RHE_PC00119(ypc00061)
RLE: pRL100370(fdhA)
RHI: NGR_c26300(fdhA1)
OAN: Oant_3453
ART: Arth_0560
AAU: AAur_0480(fdhA) AAur_1867(fdhA)
KRH: KRH_01410(fdhA)
KRA: Krad_3959
MMA: MM_0749
HWA: HQ3187A(fdh)
RCI: RCIX2285(fdh)
Taxonomy
Structures PDB: 1KOL  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:7461603]
Hohnloser W, Osswald B, Lingens F.
Enzymological aspects of caffeine demethylation and formaldehyde
oxidation by Pseudomonas putida C1.
Hoppe. Seylers. Z. Physiol. Chem. 361 (1980) 1763-6.
Pseudomonas putida
Other DBs ExplorEnz - The Enzyme Database: 1.2.1.46
IUBMB Enzyme Nomenclature: 1.2.1.46
ExPASy - ENZYME nomenclature database: 1.2.1.46
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.46
BRENDA, the Enzyme Database: 1.2.1.46
CAS: 9028-84-6
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