KEGG   ENZYME: 1.2.1.47Help
Entry
EC 1.2.1.47                 Enzyme                                 
Name
4-trimethylammoniobutyraldehyde dehydrogenase;
4-trimethylaminobutyraldehyde dehydrogenase;
4-N-trimethylaminobutyraldehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4-trimethylammoniobutanal:NAD+ 1-oxidoreductase
Reaction(IUBMB)
4-trimethylammoniobutanal + NAD+ + H2O = 4-trimethylammoniobutanoate + NADH + 2 H+ [RN:R03283]
Reaction(KEGG)
Substrate
4-trimethylammoniobutanal [CPD:C01149];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-trimethylammoniobutanoate [CPD:C01181];
NADH [CPD:C00004];
H+ [CPD:C00080]
Pathway
Lysine degradation
Orthology
K00149  
aldehyde dehydrogenase family 9 member A1
Genes
HSA: 
223(ALDH9A1)
PTR: 
457478(ALDH9A1)
PPS: 
100993750(ALDH9A1)
GGO: 
101154127(ALDH9A1)
PON: 
100173126(ALDH9A1)
MCC: 
MMU: 
56752(Aldh9a1)
RNO: 
64040(Aldh9a1)
CFA: 
478991(ALDH9A1)
AML: 
FCA: 
101080506(ALDH9A1)
BTA: 
537539(ALDH9A1)
SSC: 
100153809
ECB: 
100060577(ALDH9A1)
MDO: 
100016819
SHR: 
100932529(ALDH9A1)
OAA: 
100076925
GGA: 
424405(ALDH9A1)
MGP: 
100546048
TGU: 
100225645(ALDH9A1)
ACS: 
100555336
XLA: 
379229(aldh9a1)
XTR: 
448752(aldh9a1)
DRE: 
100005587(aldh9a1a.1) 399481(aldh9a1b)
TRU: 
101062653 101068320
OLA: 
100049493(aldh9a1) 101155544
BFO: 
BRAFLDRAFT_127028
CIN: 
100175707
SPU: 
580956 583864
ISC: 
IscW_ISCW008939
CEL: 
CELE_Y69F12A.2(alh-12)
CBR: 
CBG09190(Cbr-alh-12)
NVE: 
NEMVE_v1g192075
HMG: 
100205388
TAD: 
TRIADDRAFT_21102
 » show all
Taxonomy
Reference
1  [PMID:6770910]
  Authors
Rebouche CJ, Engel AG.
  Title
Tissue distribution of carnitine biosynthetic enzymes in man.
  Journal
Biochim. Biophys. Acta. 630 (1980) 22-9.
  Organism
Homo sapiens [GN:hsa]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
73361-01-0
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