KEGG   ENZYME: 1.2.1.47Help
Entry
EC 1.2.1.47                 Enzyme                                 

Name
4-trimethylammoniobutyraldehyde dehydrogenase;
4-trimethylaminobutyraldehyde dehydrogenase;
4-N-trimethylaminobutyraldehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4-trimethylammoniobutanal:NAD+ 1-oxidoreductase
Reaction(IUBMB)
4-trimethylammoniobutanal + NAD+ + H2O = 4-trimethylammoniobutanoate + NADH + 2 H+ [RN:R03283]
Reaction(KEGG)
Substrate
4-trimethylammoniobutanal [CPD:C01149];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-trimethylammoniobutanoate [CPD:C01181];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.2.1.47 created 1983
Pathway
Lysine degradation
Orthology
K00149  
aldehyde dehydrogenase family 9 member A1
Genes
HSA: 
223(ALDH9A1)
PTR: 
457478(ALDH9A1)
PPS: 
100993750(ALDH9A1)
GGO: 
101154127(ALDH9A1)
PON: 
100173126(ALDH9A1)
NLE: 
100594899(ALDH9A1)
MCC: 
695383(ALDH9A1)
MCF: 
102139794(ALDH9A1)
CSAB: 
103230676(ALDH9A1)
RRO: 
104670179(ALDH9A1)
CJC: 
100385191(ALDH9A1)
SBQ: 
101041228(ALDH9A1)
MMU: 
56752(Aldh9a1)
RNO: 
64040(Aldh9a1)
CGE: 
100758951(Aldh9a1)
NGI: 
103746122(Aldh9a1)
HGL: 
101717741(Aldh9a1)
OCU: 
100354540(ALDH9A1)
TUP: 
102490252(ALDH9A1)
CFA: 
478991(ALDH9A1)
AML: 
100478544(ALDH9A1)
UMR: 
103658223(ALDH9A1)
FCA: 
101080506(ALDH9A1)
PTG: 
102951347(ALDH9A1)
BTA: 
537539(ALDH9A1)
BOM: 
102268762(ALDH9A1)
PHD: 
CHX: 
102174989(ALDH9A1)
OAS: 
101109411(ALDH9A1)
SSC: 
100153809(ALDH9A1)
CFR: 
102516577(ALDH9A1)
BACU: 
103018805(ALDH9A1)
LVE: 
103080404(ALDH9A1)
ECB: 
100060577(ALDH9A1)
MYB: 
MYD: 
102768395(ALDH9A1)
PALE: 
102890956(ALDH9A1)
LAV: 
100654610(ALDH9A1)
MDO: 
100016819(ALDH9A1)
SHR: 
100932529(ALDH9A1)
OAA: 
100076925(ALDH9A1)
GGA: 
424405(ALDH9A1)
MGP: 
100546048(ALDH9A1)
CJO: 
107317241(ALDH9A1)
APLA: 
101799816(ALDH9A1)
TGU: 
100225645(ALDH9A1)
GFR: 
102035153(ALDH9A1)
FAB: 
101805672(ALDH9A1)
PHI: 
102099646(ALDH9A1)
CCW: 
104695470(ALDH9A1)
FPG: 
101920083(ALDH9A1)
FCH: 
102058365(ALDH9A1)
CLV: 
102087254(ALDH9A1)
AAM: 
106494013(ALDH9A1)
ASN: 
102375346(ALDH9A1)
AMJ: 
102576324(ALDH9A1)
PSS: 
102457679(ALDH9A1)
CMY: 
102933952(ALDH9A1)
ACS: 
100555336(aldh9a1)
PBI: 
103056986(ALDH9A1)
GJA: 
XLA: 
379229(aldh9a1.S)
XTR: 
448752(aldh9a1)
DRE: 
100005587(aldh9a1a.1) 399481(aldh9a1b)
TRU: 
TNG: 
MZE: 
OLA: 
100049493(aldh9a1) 101155544(aldh9a1)
XMA: 
SASA: 
100195073(aldh9a1)
LCM: 
102350441(ALDH9A1)
CMK: 
103180031(aldh9a1)
BFO: 
CIN: 
SPU: 
SKO: 
DPX: 
ISC: 
CEL: 
CBR: 
CBG09190(Cbr-alh-12)
BMY: 
LOA: 
HRO: 
LGI: 
CRG: 
OBI: 
NVE: 
ADF: 
HMG: 
TAD: 
 » show all
Taxonomy
Reference
1  [PMID:6770910]
  Authors
Rebouche CJ, Engel AG.
  Title
Tissue distribution of carnitine biosynthetic enzymes in man.
  Journal
Biochim. Biophys. Acta. 630 (1980) 22-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
73361-01-0

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