KEGG   ENZYME: 1.2.3.4Help
Entry
EC 1.2.3.4                  Enzyme                                 

Name
oxalate oxidase;
aero-oxalo dehydrogenase;
oxalic acid oxidase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
oxalate:oxygen oxidoreductase
Reaction(IUBMB)
oxalate + O2 + 2 H+ = 2 CO2 + H2O2 [RN:R00273]
Reaction(KEGG)
Substrate
oxalate [CPD:C00209];
O2 [CPD:C00007];
H+ [CPD:C00080]
Product
CO2 [CPD:C00011];
H2O2 [CPD:C00027]
Comment
Contains Mn2+ as a cofactor. The enzyme is not a flavoprotein as had been thought [3].
History
EC 1.2.3.4 created 1961
Pathway
Glyoxylate and dicarboxylate metabolism
Reference
1  [PMID:13250021]
  Authors
DATTA PK, MEEUSE BJ.
  Title
Moss oxalic acid oxidase-a flavoprotein.
  Journal
Biochim. Biophys. Acta. 17 (1955) 602-3.
  Organism
Hylocomium loreum, Hylocomium splendens, Rhytidiadelphus squarrosus
Reference
2  [PMID:9143327]
  Authors
Kotsira VP, Clonis YD.
  Title
Oxalate oxidase from barley roots: purification to homogeneity and study of some molecular, catalytic, and binding properties.
  Journal
Arch. Biochem. Biophys. 340 (1997) 239-49.
  Organism
Hordeum vulgare
Reference
3  [PMID:10493928]
  Authors
Requena L, Bornemann S.
  Title
Barley (Hordeum vulgare) oxalate oxidase is a manganese-containing enzyme.
  Journal
Biochem. J. 343 Pt 1 (1999) 185-90.
  Organism
Hordeum vulgare
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9031-79-2

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