KEGG   ENZYME: 1.2.3.7Help
Entry
EC 1.2.3.7                  Enzyme                                 

Name
indole-3-acetaldehyde oxidase;
indoleacetaldehyde oxidase;
IAAld oxidase;
AO1;
indole-3-acetaldehyde:oxygen oxidoreductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
(indol-3-yl)acetaldehyde:oxygen oxidoreductase
Reaction(IUBMB)
(indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2 [RN:R02681]
Reaction(KEGG)
Substrate
(indol-3-yl)acetaldehyde;
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
(indol-3-yl)acetate [CPD:C00954];
H2O2 [CPD:C00027]
Comment
A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC 1.2.3.1). It has a preference for aldehydes having an indole-ring structure as substrate [6,7]. It may play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1, than in wild-type Arabidopsis thaliana [7]. While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly. The enzyme from maize contains FAD, iron and molybdenum [4].
History
EC 1.2.3.7 created 1984, modified 2004, modified 2006
Pathway
Tryptophan metabolism
Orthology
K11817  
indole-3-acetaldehyde oxidase
Genes
ATH: 
AT3G43600(AAO2) AT5G20960(AO1)
ALY: 
CRB: 
EUS: 
TCC: 
CSV: 
VVI: 
OSA: 
DOSA: 
Os03t0790900-01(Os03g0790900) Os10t0138100-01(Os10g0138100)
OBR: 
BDI: 
SBI: 
SORBI_01g005650(SORBIDRAFT_01g005650) SORBI_01g005670(SORBIDRAFT_01g005670)
ZMA: 
542228(cl1856_2(520)) 542229(cl1856_1)
SITA: 
 » show all
Taxonomy
Reference
1  [PMID:16660220]
  Authors
Bower PJ, Brown HM, Purves WK.
  Title
Cucumber Seedling Indoleacetaldehyde Oxidase.
  Journal
Plant. Physiol. 61 (1978) 107-110.
  Organism
Cucumis sativus
Reference
2
  Authors
Miyata, S., Suzuki, Y., Kamisaka, S. and Masuda, Y.
  Title
Indole-3-acetaldehyde oxidase of pea-seedlings.
  Journal
Physiol. Plant. 51 (1981) 402-406.
Reference
3
  Authors
Rajagopal, R.
  Title
Metabolism of indole-3-acetaldehyde. III. Some characteristics of the aldehyde oxidase of Avena coleoptiles.
  Journal
Physiol. Plant. 24 (1971) 272-281.
Reference
4  [PMID:12226218]
  Authors
Koshiba T, Saito E, Ono N, Yamamoto N, Sato M.
  Title
Purification and Properties of Flavin- and Molybdenum-Containing Aldehyde Oxidase from Coleoptiles of Maize.
  Journal
Plant. Physiol. 110 (1996) 781-789.
  Organism
Zea mays
  Sequence
[zma:542228]
Reference
5  [PMID:12231908]
  Authors
Koshiba T, Matsuyama H.
  Title
An in Vitro System of Indole-3-Acetic Acid Formation from Tryptophan in Maize (Zea mays) Coleoptile Extracts.
  Journal
Plant. Physiol. 102 (1993) 1319-1324.
  Organism
Zea mays
Reference
6  [PMID:9615466]
  Authors
Sekimoto H, Seo M, Kawakami N, Komano T, Desloire S, Liotenberg S, Marion-Poll A, Caboche M, Kamiya Y, Koshiba T.
  Title
Molecular cloning and characterization of aldehyde oxidases in Arabidopsis thaliana.
  Journal
Plant. Cell. Physiol. 39 (1998) 433-42.
  Organism
Arabidopsis thaliana
  Sequence
Reference
7  [PMID:9489015]
  Authors
Seo M, Akaba S, Oritani T, Delarue M, Bellini C, Caboche M, Koshiba T.
  Title
Higher activity of an aldehyde oxidase in the auxin-overproducing superroot1 mutant of Arabidopsis thaliana.
  Journal
Plant. Physiol. 116 (1998) 687-93.
  Organism
Arabidopsis thaliana
  Sequence
[ath:AT5G20960]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
66082-22-2

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