| Entry |
|
|---|
| Name |
2,4-dichlorobenzoyl-CoA reductase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating) |
|---|
| Reaction(IUBMB) |
4-chlorobenzoyl-CoA + NADP+ + HCl = 2,4-dichlorobenzoyl-CoA + NADPH
+ H+ [RN:R05276] |
|---|
| Reaction(KEGG) |
R05276
 |
|---|
| Substrate |
4-chlorobenzoyl-CoA [CPD:C06387];
NADP+ [CPD:C00006];
HCl [CPD:C01327] |
|---|
| Product |
2,4-dichlorobenzoyl-CoA [CPD:C06671];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
Acts in the reverse direction to form part of the
2,4-dichlorobenzoate degradation pathway in bacteria. |
|---|
| Pathway |
PATH: ec00623 2,4-Dichlorobenzoate degradation
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:8626335]
Romanov V, Hausinger RP.
NADPH-dependent reductive ortho dehalogenation of
2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and
Coryneform bacterium strainNTB-1 via 2,4-dichlorobenzoyl coenzyme A.
J. Bacteriol. 178 (1996) 2656-61.
Corynebacterium sepedonicum, Coryneform bacterium |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.1.63
IUBMB Enzyme Nomenclature: 1.3.1.63
ExPASy - ENZYME nomenclature database: 1.3.1.63
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.63
BRENDA, the Enzyme Database: 1.3.1.63 |
|---|
