KEGG   ENZYME: 1.3.99.17Help
Entry
EC 1.3.99.17                Enzyme                                 

Name
quinoline 2-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With other acceptors
BRITE hierarchy
Sysname
quinoline:acceptor 2-oxidoreductase (hydroxylating)
Reaction(IUBMB)
quinoline + acceptor + H2O = quinolin-2(1H)-one + reduced acceptor [RN:R05152]
Reaction(KEGG)
Substrate
quinoline [CPD:C06413];
acceptor [CPD:C00028];
H2O [CPD:C00001]
Product
quinolin-2(1H)-one [CPD:C06415];
reduced acceptor [CPD:C00030]
Comment
Quinolin-2-ol, quinolin-7-ol, quinolin-8-ol, 3-, 4- and 8-methylquinolines and 8-chloroquinoline are substrates. Iodonitrotetrazolium chloride can act as an electron acceptor.
History
EC 1.3.99.17 created 1999
Reference
1  [PMID:2090161]
  Authors
Bauder R, Tshisuaka B, Lingens F.
  Title
Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme.
  Journal
Biol. Chem. Hoppe. Seyler. 371 (1990) 1137-44.
  Organism
Pseudomonas putida
Reference
2  [PMID:8251516]
  Authors
Tshisuaka B, Kappl R, Huttermann J, Lingens F.
  Title
Quinoline oxidoreductase from Pseudomonas putida 86: an improved purification procedure and electron paramagnetic resonance spectroscopy.
  Journal
Biochemistry. 32 (1993) 12928-34.
  Organism
Pseudomonas putida
Reference
3  [PMID:1789933]
  Authors
Peschke B, Lingens F.
  Title
Microbial metabolism of quinoline and related compounds. XII. Isolation and characterization of the quinoline oxidoreductase from Rhodococcus spec. B1 compared with the quinoline oxidoreductase from Pseudomonas putida 86.
  Journal
Biol. Chem. Hoppe. Seyler. 372 (1991) 1081-8.
  Organism
Pseudomonas putida, Rhodococcus sp.
Reference
4  [PMID:7556204]
  Authors
Schach S, Tshisuaka B, Fetzner S, Lingens F.
  Title
Quinoline 2-oxidoreductase and 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase from Comamonas testosteroni 63. The first two enzymes in quinoline and 3-methylquinoline degradation.
  Journal
Eur. J. Biochem. 232 (1995) 536-44.
  Organism
Comamonas testosteroni
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
132264-32-5

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