quinaldate 4-oxidoreductase;
quinaldic acid 4-oxidoreductase

Oxidoreductases;
Acting on the CH-CH group of donors;
With other acceptors

quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating)

quinaldate + acceptor + H2O = kynurenate + reduced acceptor [RN:R03687]

R03687

quinaldate [CPD:C06325];
acceptor [CPD:C00028];
H2O [CPD:C00001]

The enzyme from Pseudomonas sp. AK2 also acts on quinoline-8-carboxylate, whereas that from Serratia marcescens 2CC-1 will oxidize nicotinate; quinaldate is a substrate for both of these enzymes. 2,4,6-Trinitrobenzene sulfonate, 1,4-benzoquinone, 1,2-naphthoquinone, nitroblue tetrazolium, thionine and menadione will serve as an electron acceptor for the former enzyme and ferricyanide for the latter; Meldola blue, iodonitrotetrazolium chloride, phenazine methosulfate, 2,6-dichlorophenolindophenol and cytochrome c will act as electron acceptors for both.

1  [PMID:8292263]

Sauter M, Tshisuaka B, Fetzner S, Lingens F.

Microbial metabolism of quinoline and related compounds. XX. Quinaldic acid 4-oxidoreductase from Pseudomonas sp. AK-2 compared to other procaryotic molybdenum-containing hydroxylases.

Biol. Chem. Hoppe. Seyler. 374 (1993) 1037-46.

Pseudomonas sp.

2  [PMID:8357532]

Fetzner S, Lingens F.

Microbial metabolism of quinoline and related compounds. XVIII. Purification and some properties of the molybdenum- and iron-containing quinaldic acid 4-oxidoreductase from Serratia marcescens 2CC-1.

Biol. Chem. Hoppe. Seyler. 374 (1993) 363-76.

Serratia marcecens