KEGG   ENZYME: 1.4.3.2Help
Entry
EC 1.4.3.2                  Enzyme                                 

Name
L-amino-acid oxidase;
ophio-amino-acid oxidase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
L-amino-acid:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
an L-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2 [RN:R01259]
Reaction(KEGG)
Substrate
L-amino acid [CPD:C00151];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
2-oxo carboxylate;
NH3 [CPD:C00014];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD).
History
EC 1.4.3.2 created 1961
Pathway
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine degradation
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Isoquinoline alkaloid biosynthesis
Metabolic pathways
Orthology
K03334  
L-amino-acid oxidase
Genes
HSA: 
259307(IL4I1)
PTR: 
456223(IL4I1)
PPS: 
100980850(IL4I1)
GGO: 
101153847(IL4I1)
PON: 
MCC: 
719114(IL4I1)
MCF: 
102115096(IL4I1)
MMU: 
100328588(Nup62-il4i1) 100470(Lao1) 14204(Il4i1) 73988(4930438A08Rik)
RNO: 
100360621 287305(RGD1308564) 298483(Lao1)
CGE: 
HGL: 
101710424(Il4i1)
TUP: 
CFA: 
482436 484371(IL4I1)
AML: 
FCA: 
BTA: 
BOM: 
PHD: 
CHX: 
SSC: 
CFR: 
ECB: 
MYB: 
MDO: 
SHR: 
GGA: 
417039(IL4I1)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FCH: 
CLV: 
ASN: 
ACS: 
XTR: 
DRE: 
337166(fa99f01)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
 » show all
Taxonomy
Reference
1
  Authors
Meister, A. and Wellner, D.
  Title
Flavoprotein amino acid oxidase.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 609-648.
Reference
2  [PMID:13843884]
  Authors
WELLNER D, MEISTER A.
  Title
Crystalline L-amino acid oxidase of Crotalus adamanteus.
  Journal
J. Biol. Chem. 235 (1960) 2013-8.
  Organism
Crotalus adamanteus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9000-89-9

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