KEGG   ENZYME: 1.4.3.2Help
Entry
EC 1.4.3.2                  Enzyme                                 
Name
L-amino-acid oxidase;
ophio-amino-acid oxidase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
L-amino-acid:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
an L-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2 [RN:R01259]
Reaction(KEGG)
Substrate
L-amino acid [CPD:C00151];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
2-oxo carboxylate;
NH3 [CPD:C00014];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD).
Pathway
Alanine, aspartate and glutamate metabolism
Cysteine and methionine metabolism
Valine, leucine and isoleucine degradation
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Isoquinoline alkaloid biosynthesis
Metabolic pathways
Orthology
K03334  
L-amino-acid oxidase
Genes
HSA: 
259307(IL4I1)
PTR: 
456223(IL4I1)
PPS: 
100980850(IL4I1)
GGO: 
101153847(IL4I1)
PON: 
MCC: 
719114(IL4I1)
MMU: 
100328588(Nup62-il4i1) 100470(Lao1) 14204(Il4i1) 73988(4930438A08Rik)
RNO: 
100360621 287305(RGD1308564) 298483(Lao1)
CFA: 
482436 484371(IL4I1)
AML: 
FCA: 
101100400 101100683(IL4I1)
BTA: 
520692 782545
SSC: 
100522257(IL4I1) 100525099
ECB: 
100055246 100147151 100147304
MDO: 
100010068 100032718
SHR: 
100917854 100923259 100932442
GGA: 
417039(IL4I1)
MGP: 
100540143
TGU: 
100222394
ACS: 
100563852 100566795
XTR: 
100493881 100496394
DRE: 
337166(fa99f01)
TRU: 
101072153
OLA: 
101161073 101163441
 » show all
Taxonomy
Reference
1
  Authors
Meister, A. and Wellner, D.
  Title
Flavoprotein amino acid oxidase.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 609-648.
Reference
2  [PMID:13843884]
  Authors
WELLNER D, MEISTER A.
  Title
Crystalline L-amino acid oxidase of Crotalus adamanteus.
  Journal
J. Biol. Chem. 235 (1960) 2013-8.
  Organism
Crotalus adamanteus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9000-89-9
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