KEGG   ENZYME: 1.8.99.2Help
Entry
EC 1.8.99.2                 Enzyme                                 

Name
adenylyl-sulfate reductase;
adenosine phosphosulfate reductase;
adenosine 5'-phosphosulfate reductase;
APS-reductase;
APS reductase;
AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With other, unknown, acceptors
BRITE hierarchy
Sysname
AMP,sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)
Reaction(IUBMB)
AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor [RN:R00860]
Reaction(KEGG)
R00860 > R08553;
(other) R04927
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Substrate
AMP [CPD:C00020];
sulfite [CPD:C00094];
acceptor [CPD:C00028]
Product
adenylyl sulfate [CPD:C00224];
reduced acceptor [CPD:C00030]
Comment
An iron flavoprotein (FAD). Methyl viologen can act as acceptor.
History
EC 1.8.99.2 created 1972
Pathway
Sulfur metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K00394  
adenylylsulfate reductase, subunit A
K00395  
adenylylsulfate reductase, subunit B
Genes
ALV: 
TVI: 
TMB: 
TGR: 
TKM: 
TNI: 
RMA: 
VOK: 
COSY_0091(aprB) COSY_0092(aprA)
TBD: 
SDR: 
SLT: 
DVU: 
DVU0846(aprB) DVU0847(aprA)
DVL: 
DVM: 
DVG: 
DDE: 
DDS: 
DDN: 
DMA: 
DSA: 
DAS: 
DAF: 
DHY: 
DPI: 
BN4_11809(aprA) BN4_11810(aprB)
DGG: 
DGI_0457(aprA) DGI_0458(aprB)
DBA: 
DRT: 
DPS: 
DAK: 
DPR: 
DSF: 
DOL: 
DAL: 
DAT: 
DTO: 
DAO: 
DTI: 
SFU: 
DBR: 
PUB: 
APM: 
CAC: 
CAE: 
CAY: 
CBE: 
CBZ: 
CKL: 
CKR: 
CCB: 
CLS: 
CSR: 
CPAS: 
CSB: 
CLT: 
AMT: 
RBR: 
RUM: 
CLE: 
COO: 
ROB: 
CPY: 
CAD: 
DRM: 
DAE: 
DCA: 
DKU: 
DRU: 
DGI: 
PTH: 
DAU: 
TJR: 
DOR: 
DAI: 
DMI: 
EEL: 
ERE: 
ERT: 
ERA: 
BPRL: 
CHY: 
ADG: 
CSC: 
ATE: 
CHD: 
CKI: 
CKN: 
TNR: 
HOR: 
AAR: 
HHL: 
SRI: 
MED: 
PUF: 
FSU: 
FSC: 
IPO: 
LBA: 
CTE: 
CT0864(aspB) CT0865(apsA)
CCH: 
CPB: 
PPH: 
TYE: 
LFC: 
LFI: 
LFP: 
TID: 
TOP: 
TCM: 
AFU: 
AF1669(aprB) AF1670(aprA)
AFG: 
APO: 
AVE: 
AST: 
FPL: 
PAI: 
PCL: 
PAS: 
PYR: 
POG: 
CMA: 
TUZ: 
TTN: 
VDI: 
VMO: 
 » show all
Taxonomy
Reference
1  [PMID:5421934]
  Authors
Michaels GB, Davidson JT, Peck HD Jr.
  Title
A flavin-sulfite adduct as an intermediate in the reaction catalyzed by adenylyl sulfate reductase from Desulfovibrio vulgaris.
  Journal
Biochem. Biophys. Res. Commun. 39 (1970) 321-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9027-75-2

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