| Entry |
|
|---|
| Name |
nicotinamide N-methyltransferase;
nicotinamide methyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:nicotinamide N-methyltransferase |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine +
1-methylnicotinamide [RN:R01269] |
|---|
| Reaction(KEGG) |
R01269
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
nicotinamide [CPD:C00153] |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
1-methylnicotinamide [CPD:C02918] |
|---|
| Pathway |
ec00760 Nicotinate and nicotinamide metabolism
ec01100 Metabolic pathways |
|---|
| Orthology |
K00541 nicotinamide N-methyltransferase |
|---|
| Genes |
HSA: 4837(NNMT)
PTR: 451558(NNMT)
MCC: 695185
MMU: 18113(Nnmt)
RNO: 300691(Nnmt)
CFA: 489396(NNMT)
ECB: 100070819
MDO: 100032114
OAA: 100080750
DRE: 393330(MGC174522)
NVE: NEMVE_v1g164399
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14832232]
CANTONI GL.
Methylation of nicotinamide with soluble enzyme system from rat
liver.
J. Biol. Chem. 189 (1951) 203-16.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.1
IUBMB Enzyme Nomenclature: 2.1.1.1
ExPASy - ENZYME nomenclature database: 2.1.1.1
BRENDA, the Enzyme Database: 2.1.1.1
CAS: 9029-74-7 |
|---|
