| Entry |
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| Name |
nicotinamide N-methyltransferase;
nicotinamide methyltransferase
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:nicotinamide N-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-methylnicotinamide [RN: R01269]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
nicotinamide [CPD: C00153]
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
1-methylnicotinamide [CPD: C02918]
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| Pathway |
| Nicotinate and nicotinamide metabolism | | Metabolic pathways |
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| Orthology |
| nicotinamide N-methyltransferase |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | ACS: | | XLA: | | XTR: | | DRE: | | BFO: | | ISC: | | BMY: | | TSP: | | NVE: | |
» show all
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| Reference |
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| Authors |
CANTONI GL. |
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| Title |
Methylation of nicotinamide with soluble enzyme system from rat liver. |
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| Journal |
J. Biol. Chem. 189 (1951) 203-16. |
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| Organism |
Rattus norvegicus [GN: rno] |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 9029-74-7 |
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