KEGG   ENZYME: 2.1.1.154Help
Entry
EC 2.1.1.154                Enzyme                                 

Name
isoliquiritigenin 2'-O-methyltransferase;
chalcone OMT;
CHMT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + isoliquiritigenin = S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin [RN:R07242]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
isoliquiritigenin [CPD:C08650]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
2'-O-methylisoliquiritigenin [CPD:C15531]
Comment
Not identical to EC 2.1.1.65, licodione 2'-O-methyltransferase [2]. While EC 2.1.1.154, isoliquiritigenin 2'-O-methyltransferase can use licodione as a substrate, EC 2.1.1.65 cannot use isoliquiritigenin as a substrate.
History
EC 2.1.1.154 created 2004
Reference
1  [PMID:1731632]
  Authors
Maxwell CA, Edwards R, Dixon RA.
  Title
Identification, purification, and characterization of S-adenosyl-L-methionine: isoliquiritigenin 2'-O-methyltransferase from alfalfa (Medicago sativa L.).
  Journal
Arch. Biochem. Biophys. 293 (1992) 158-66.
  Organism
Medicago sativa
  Sequence
[up:P93324]
Reference
2  [PMID:9055445]
  Authors
Ichimura M, Furuno T, Takahashi T, Dixon RA, Ayabe S.
  Title
Enzymic O-methylation of isoliquiritigenin and licodione in alfalfa and licorice cultures.
  Journal
Phytochemistry. 44 (1997) 991-5.
  Organism
Medicago sativa
  Sequence
[up:P93324]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
139317-14-9

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