KEGG   ENZYME: 2.1.1.43Help
Entry
EC 2.1.1.43                 Enzyme                                 

Name
histone-lysine N-methyltransferase;
protein methylase III;
protein methylase 3;
protein (lysine) methyltransferase;
protein methyltransferase II;
protein-lysine N-methyltransferase;
histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase;
S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine [RN:R03938]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
histone L-lysine
Product
S-adenosyl-L-homocysteine [CPD:C00021];
histone N6-methyl-L-lysine [CPD:C03702]
Comment
One of a group of enzymes methylating proteins; see also EC 2.1.1.59, [cytochrome-c]-lysine N-methyltransferase and EC 2.1.1.60, calmodulin-lysine N-methyltransferase.
History
EC 2.1.1.43 created 1976, modified 1982, modified 1983
Pathway
Lysine degradation
Orthology
K06101  
histone-lysine N-methyltransferase ASH1L
K09186  
histone-lysine N-methyltransferase MLL1
K09187  
histone-lysine N-methyltransferase MLL2
K09188  
histone-lysine N-methyltransferase MLL3
K09189  
histone-lysine N-methyltransferase MLL5
K11419  
histone-lysine N-methyltransferase SUV39H
K11420  
euchromatic histone-lysine N-methyltransferase
K11421  
histone-lysine N-methyltransferase SETDB
K11422  
histone-lysine N-methyltransferase SETD1
K11423  
histone-lysine N-methyltransferase SETD2
K11424  
histone-lysine N-methyltransferase NSD2
K11425  
histone-lysine N-methyltransferase NSD3
K11427  
histone-lysine N-methyltransferase, H3 lysine-79 specific
K11428  
histone-lysine N-methyltransferase SETD8
K11429  
histone-lysine N-methyltransferase SUV420H
K11430  
histone-lysine N-methyltransferase EZH2
K11431  
histone-lysine N-methyltransferase SETD7
K11433  
histone-lysine N-methyltransferase SETMAR
K14959  
histone-lysine N-methyltransferase MLL4
K15588  
histone-lysine N-methyltransferase NSD1
K17451  
histone-lysine N-methyltransferase EZH1
Genes
HSA: 
10919(EHMT2) 2145(EZH1) 2146(EZH2) 23067(SETD1B) 29072(SETD2) 387893(SETD8) 4297(KMT2A) 51111(SUV420H1) 54904(WHSC1L1) 55870(ASH1L) 55904(KMT2E) 58508(KMT2C) 6419(SETMAR) 64324(NSD1) 6839(SUV39H1) 7468(WHSC1) 79723(SUV39H2) 79813(EHMT1) 8085(KMT2D) 80854(SETD7) 83852(SETDB2) 84444(DOT1L) 84787(SUV420H2) 9739(SETD1A) 9757(KMT2B) 9869(SETDB1)
PTR: 
100610362 101058641(ASH1L) 451378(SUV420H1) 451587(MLL) 451873(MLL2) 452343(SETD8) 452719(SETDB2) 454697(EZH1) 455566(DOT1L) 455959 460331(SETD2) 461070(WHSC1) 462572(EHMT2) 463640(MLL5) 463875(MLL3) 464119(WHSC1L1) 464891(EHMT1) 465618 466014(SUV39H2) 468101(SETD1A) 469481(SETDB1) 470738(SETMAR) 471754(NSD1) 473295 735868(SUV420H2) 737682(SETD7) 745437(EZH2)
PPS: 
100967877(EZH1) 100968253(EHMT1) 100969530(DOT1L) 100971244(EZH2) 100972839(SETDB1) 100972983(SETD1A) 100977497(SUV39H1) 100978154 100979249 100979709(ASH1L) 100981554(SETD7) 100982469(SUV39H2) 100982828(MLL5) 100984020(SUV420H2) 100984332(MLL) 100986203(SETMAR) 100986737(SETD8) 100986951(SETDB2) 100989573(WHSC1L1) 100991724(EHMT2) 100991882(NSD1) 100992231(MLL3) 100993006(SETD2) 100993332(WHSC1) 100995372(SUV420H1) 100995808(MLL2)
GGO: 
101124677 101126338(SUV39H2) 101126515(EZH1) 101126745 101127408(WHSC1L1) 101129366(MLL) 101131467 101132140(SETD2) 101134264(ASH1L) 101134599(MLL3) 101134931(DOT1L) 101136477(SETD7) 101139439(SUV420H2) 101139808(EHMT2) 101139923 101140725(WHSC1) 101141713(SETDB2) 101143612 101144774(MLL2) 101145513(SETD8) 101146215(SETDB1) 101146540(SUV39H1) 101147968(EZH2) 101150409(SETMAR) 101151252(SUV420H1) 101151843(EHMT1)
PON: 
100171872(EZH1) 100172621(SUV39H1) 100173903(MLL5) 100432076(SETD1A) 100433116(SETD2) 100433878(WHSC1) 100436926(SUV39H2) 100437200 100441102(MLL) 100441715(MLL2) 100447447(EZH2) 100447656(SETMAR) 100449956(SETD7) 100450271(SUV420H1) 100450564(DOT1L) 100450936 100451228(MLL3) 100451760(SETD8) 100459660(WHSC1L1) 100460372(EHMT2) 100461473(NSD1) 100461671(SETDB1)
MCC: 
697233 697378(SUV39H2) 699963(SUV420H2) 700254(WHSC1L1) 700426(SETD7) 703717 703880(SETMAR) 705511(MLL) 706131(NSD1) 706277(SETDB2) 709075(EZH2) 709345(SETD8) 710033(DOT1L) 710481(SUV420H1) 710795(MLL2) 711040(SUV39H1) 711173(EZH1) 711825(SETD2) 712416 712618 715824(EHMT2) 716141(SETDB1) 716753(MLL3) 718835(MLL4) 721470
MCF: 
101866311 101867084 101867194 101926094 101926502 102115861(KMT2B) 102117388(SUV420H1) 102117410(SETDB1) 102120529(NSD1) 102121581(SETD2) 102123137(SETD1B) 102123773(KMT2D) 102124788(SETDB2) 102125769(EHMT1) 102128002(KMT2C) 102128021(SETD8) 102129054(SUV420H2) 102130547(EZH1) 102132914(WHSC1) 102134166(SETD1A) 102134179(SUV39H1) 102136014(SUV39H2) 102138188(WHSC1L1) 102139754(EHMT2) 102140141(SETD7) 102146280(EZH2)
MMU: 
107823(Whsc1) 110147(Ehmt2) 14055(Ezh1) 14056(Ezh2) 18193(Nsd1) 192195(Ash1l) 208043(Setd1b) 208266(Dot1l) 20937(Suv39h1) 214162(Kmt2a) 225888(Suv420h1) 231051(Kmt2c) 232811(Suv420h2) 233904(Setd1a) 234135(Whsc1l1) 235626(Setd2) 239122(Setdb2) 381022(Kmt2d) 64707(Suv39h2) 67956(Setd8) 69188(Kmt2e) 73251(Setd7) 74729(Setmar) 75410(Kmt2b) 77683(Ehmt1) 84505(Setdb1)
RNO: 
100359816 100361710(Setdb2) 100362634(Kmt2d) 100909949 288346(RGD1561853) 290831(Whsc1l1) 302553(Suv39h1) 303547(Ezh1) 306764(Nsd1) 308345(Suv420h2) 310638(Ash1l) 311968(Kmt2e) 312299(Ezh2) 315606(Kmt2a) 316013(Setd2) 361688(Suv420h1) 361798(Ehmt2) 362078(Ehmt1) 362831(Dot1l) 362996(Mll2l) 364785(Suv39h2) 500281(Setmar) 502710(Kmt2c) 680537(Whsc1) 689820(Setd8) 689883(Setdb1) 689954(Setd7)
CGE: 
HGL: 
101696702(Setdb2) 101697232(Ehmt2) 101698170(Kmt2c) 101698401(Nsd1) 101699104(Ehmt1) 101699273(Zbtb32) 101701917(Suv39h2) 101702710(Ezh2) 101702850(Setd1b) 101703406(Whsc1l1) 101704237(Setmar) 101706867(Suv39h1) 101707567(Suv420h2) 101709197(Setd1a) 101709487(Whsc1) 101712321(Kmt2e) 101712712(Dot1l) 101715248(Setdb1) 101715832(Setd7) 101716157 101716671(Kmt2a) 101718411(Kmt2d) 101719039(Suv420h1) 101719404(Setd2) 101723063(Ezh1) 101723836(Ash1l) 101726359(Setd8)
TUP: 
102468719 102469064(SETMAR) 102469443(ASH1L) 102470517(SETD7) 102471250(SETD8) 102473382(KMT2A) 102474223(SETD1B) 102476810(NSD1) 102477041 102477772(KMT2B) 102477917(SETD2) 102478405(SETD1A) 102479012(KMT2C) 102479735(EHMT2) 102480722(KMT2D) 102483069(KMT2E) 102485788(EZH1) 102487161(WHSC1L1) 102494943(DOT1L) 102495109(SUV39H2) 102495627(EZH2) 102497986(SUV420H1) 102498729(EHMT1) 102499452(SUV420H2) 102501548(WHSC1) 102502264(SETDB1) 102502765 102503290(SETDB2)
CFA: 
100688666(MLL4) 474851(EHMT2) 475511(EZH2) 475584(WHSC1L1) 475895(KMT2E) 476079(SETD7) 476549(SETMAR) 476643(SETD2) 477995(SUV39H2) 479077(WHSC1) 479417(KMT2A) 480128(ASH1L) 480516(EZH1) 483186(SETDB1) 483690(SUV420H1) 484295(SUV420H2) 485073(DOT1L) 485441(SETDB2) 486257(SETD1B) 486558(KMT2D) 489094(NSD1) 489916(SETD1A) 491224(EHMT1) 491868(SUV39H1) 610615(SETD8) 611094(MLL3)
AML: 
FCA: 
101083169(WHSC1) 101083571(SUV39H1) 101084095(KMT2C) 101084945(KMT2E) 101085029(SETD2) 101086008(SETD8) 101086114(ASH1L) 101086901(WHSC1L1) 101087111(EHMT1) 101087309(EZH2) 101088560(SETMAR) 101090288(KMT2A) 101091070(SETD1A) 101091191(SETD7) 101091322(SUV420H2) 101091940(EHMT2) 101094118(SETDB1) 101094702(SUV420H1) 101095268(KMT2D) 101096419(SETD1B) 101098760(KMT2B) 101099218(SUV39H2) 101099602(EZH1) 101100356(SETDB2) 101100618(NSD1) 101101194(DOT1L)
PTG: 
102949086(WHSC1L1) 102949117(KMT2E) 102950897(SUV39H1) 102953097(SUV420H2) 102953445(SETD7) 102954489(EHMT1) 102955436(SETD2) 102956220(EZH2) 102956940(KMT2A) 102959131(WHSC1) 102961028(EZH1) 102962714(SETD8) 102962859(KMT2D) 102962904(SETDB2) 102963329(SUV420H1) 102963752(SUV39H2) 102964154(KMT2C) 102964395(SETMAR) 102964982(KMT2B) 102965041 102966497(DOT1L) 102967043(NSD1) 102968259(EHMT2) 102968914 102969005(SETD1A) 102969379(ASH1L) 102970685(SETD1B) 102970727(SETDB1)
BTA: 
100138100(SETDB1) 101907695 506805(KMT2D) 508330(KMT2A) 509106(EZH2) 509382(SETDB2) 510442(DOT1L) 511299(SETMAR) 513054(WHSC1L1) 514062(EHMT2) 514102(SETD1B) 515928(SETD7) 519777(SUV420H2) 523047(SUV39H1) 528606(EHMT1) 532622(SETD8) 533087(EZH1) 534913 536936(SUV39H2) 539121(MLL5) 539860(SETD2) 540197(NSD1) 540563(ASH1L) 540769(WHSC1) 767828(SUV420H1) 782887(SETD1A) 785776(KMT2B) 789336(KMT2C)
BOM: 
102264389(WHSC1) 102264756(SUV39H2) 102264795(SETD8) 102265377 102266643(SETD2) 102267186(KMT2C) 102268256(SETMAR) 102268312(SUV420H1) 102268569(NSD1) 102268887(KMT2D) 102268973(WHSC1L1) 102269320(KMT2B) 102271111(EHMT1) 102271191(SUV39H1) 102275046(ASH1L) 102276653(EZH1) 102279495(SETD1A) 102279999(EHMT2) 102280025(KMT2A) 102280610(SETD1B) 102280735(DOT1L) 102281278(KMT2E) 102281809(SETD7) 102287560(SETDB2) 102288279(SETDB1) 102288327(SUV420H2)
PHD: 
102315799(NSD1) 102315964(EZH1) 102316666 102317218(KMT2E) 102317507(KMT2C) 102318631(SETD1B) 102318931(SUV420H2) 102319778(DOT1L) 102321056(KMT2B) 102321635(SUV39H2) 102324798(SETD2) 102325434(WHSC1) 102325445(SETMAR) 102325764(SUV39H1) 102327416(ASH1L) 102329173(SETDB1) 102329944(SETD1A) 102330271(EHMT1) 102331445(SUV420H1) 102332319(KMT2A) 102335328(EZH2) 102335400(SETD8) 102336661(KMT2D) 102337462(SETD7) 102339010(EHMT2) 102342787 102343350(SETDB2) 102344433(WHSC1L1)
CHX: 
102168698 102169033(KMT2A) 102169548(KMT2E) 102170478(SETD1A) 102172292(KMT2B) 102174919(SUV39H1) 102176621(SUV39H2) 102177756 102178316(EHMT2) 102179971(SETD1B) 102180119(DOT1L) 102180350 102180982(SETDB1) 102181925 102183113(SETD2) 102183718(SETD8) 102184804(NSD1) 102185214(SUV420H2) 102185413(ASH1L) 102185720(SUV420H1) 102186471(WHSC1) 102186776(SETDB2) 102188284(WHSC1L1) 102189343(EZH1) 102189411(EHMT1) 102189632(SETMAR) 102190101(EZH2) 102191824(SETD7)
SSC: 
100124382(EHMT2) 100155920(ASH1L) 100156137(SETD1B) 100157885(SETDB2) 100157920(SETDB1) 100511747(SETD1A) 100513150(KMT2D) 100514009(SETMAR) 100514805(KMT2C) 100515039(WHSC1) 100518394(EZH1) 100520742(KMT2B) 100520868(WHSC1L1) 100521358(SUV420H1) 100524976(NSD1) 100623006(KMT2A) 100623101(SETD2) 100625497(EZH2) 100626246 100626555(SETD8) 100626704(SETD7) 100628131(KMT2E) 100738592 100738665(DOT1L) 664651(SUV39H2)
CFR: 
102506865(SETD7) 102507730(KMT2C) 102509336(NSD1) 102509980(SETD1A) 102510601(ASH1L) 102512057(SETDB1) 102512396(SETD2) 102512972(SUV39H1) 102513372(WHSC1) 102514543(KMT2E) 102514903(SETDB2) 102515223(KMT2D) 102515779(WHSC1L1) 102515793(EZH2) 102516907(EZH1) 102517824(KMT2A) 102518579(EHMT2) 102520054(SUV420H1) 102520520(KMT2B) 102521199(SUV39H2) 102521372(SETD1B) 102521526(EHMT1) 102521782(SETD8) 102522071(DOT1L) 102523255(SETMAR)
ECB: 
100051090(WHSC1) 100051290(EZH2) 100052411(EZH1) 100053438(SUV420H1) 100055743(SUV420H2) 100056120(SETDB2) 100057386(ASH1L) 100057692(WHSC1L1) 100058570(NSD1) 100058869(EHMT1) 100058928(KMT2E) 100058932(KMT2D) 100059118(EHMT2) 100059254(SETDB1) 100059802(KMT2B) 100059905(SETMAR) 100060853(SETD8) 100062108(SUV39H1) 100063257(SETD7) 100063523(SETD1A) 100064812(KMT2C) 100064888(SETD2) 100068506(DOT1L) 100068891(SUV39H2) 100071238(KMT2A) 100146430(SETD1B)
MYB: 
102240787(DOT1L) 102240957 102242179 102243180(SUV39H1) 102244965(KMT2D) 102245485(EHMT1) 102246299(EZH2) 102246410(KMT2E) 102246482(SETD7) 102246704(KMT2C) 102246785(KMT2A) 102248401(SETDB2) 102252817(WHSC1L1) 102253255(SETD1A) 102253280(WHSC1) 102255512(SETD1B) 102256394(ASH1L) 102257499(NSD1) 102257692(SUV420H1) 102257713(SETDB1) 102259087(KMT2B) 102259730(EZH1) 102260054(SUV39H2) 102260404(SETD2) 102261854(SETMAR) 102263672(EHMT2) 102263856
MYD: 
102751347(SETD1B) 102755313(EZH1) 102756071(SETD1A) 102756540(EHMT1) 102757145(SUV39H2) 102758485(SETD2) 102758785(KMT2E) 102759674(KMT2C) 102759770(WHSC1L1) 102760166(SETD7) 102760242 102761630(SUV420H2) 102761804(SETMAR) 102762410(KMT2D) 102762755(SUV420H1) 102763954(SUV39H1) 102764253 102764796(ASH1L) 102764830(NSD1) 102765299(SETDB2) 102766910(KMT2A) 102768989(EZH2) 102770785(SETD8) 102771251(KMT2B) 102773641(DOT1L) 102773684(SETDB1) 102773857(EHMT2) 102775482(WHSC1)
PALE: 
102877851 102879153(SETD1B) 102879344(WHSC1L1) 102879374(EHMT2) 102879627(EZH1) 102879695(NSD1) 102881431(KMT2B) 102884085(SETD2) 102884674(SETD1A) 102886191(SETDB1) 102886689(EZH2) 102887326(SUV420H1) 102887846(SUV420H2) 102888124(ASH1L) 102888384(KMT2E) 102888593(KMT2D) 102890289(SETD7) 102891996(SETDB2) 102893102(EHMT1) 102893336(KMT2A) 102893368(DOT1L) 102894853(SUV39H1) 102895479(SETMAR) 102897218(WHSC1) 102897510(SETD8) 102897550(KMT2C) 102898400(SUV39H2)
MDO: 
100010281(SUV420H1) 100010738(EZH1) 100013387(SETD1A) 100013390(EZH2) 100014806(SUV39H2) 100017118(ASH1L) 100018670 100019161(KMT2C) 100022449(SETMAR) 100022914(WHSC1) 100023739(SETD8) 100023838(EHMT1) 100024848(SETD2) 100027436(SETD7) 100028710(SETDB2) 100029834(WHSC1L1) 100031440(KMT2A) 100031881(NSD1) 100618514(SETD1B) 100618580(SETDB1) 100619840(DOT1L)
SHR: 
100913201(NSD1) 100913447(WHSC1) 100913907(WHSC1L1) 100917457(SUV420H1) 100918271(SETMAR) 100918350(DOT1L) 100920575(MLL3) 100922144(MLL5) 100922258 100924557(MLL) 100925717 100926678(EZH2) 100926753 100927672 100928096 100928575(MLL2) 100928904(SETDB1) 100929066(SUV420H2) 100929261(SETD7) 100929291(SETD1A) 100930822 100931147(EHMT2) 100931585(ASH1L) 100931646(SETD2) 100932535(EZH1) 100932927(EHMT1) 100933547(SETD8) 100933751(SUV39H2) 100934863(SETDB2)
OAA: 
100073485(EZH2) 100074284(WHSC1L1) 100074286(KMT2C) 100074411 100075708 100075898(SETD8) 100077208(KMT2E) 100078328(EHMT1) 100079266(SETD1B) 100081674(SETD7) 100083315(SETDB2) 100085175(SUV39H2) 100086259(WHSC1) 100088070
GGA: 
100857640(SUV39H1) 101747682 101751150 395847(SETDB1) 414897(MLL) 416214(NSD1) 416825(SETD8) 416851(SETD1B) 417250(EHMT1) 417712(MLL5) 418866(SETDB2) 420023(EZH1) 420078(DOT1L) 420404(SETD2) 420437(MLL3) 420784(EZH2) 422443(SETD7) 422897(WHSC1) 425064(ASH1L) 425119(SUV420H1) 425846(MLL2) 426314(SUV39H2) 426778(WHSC1L1)
MGP: 
TGU: 
100217666(EHMT1) 100219478 100219515(NSD1) 100219994(SETD7) 100222310(DOT1L) 100222344 100222807(WHSC1) 100222904(SUV420H1) 100224170(WHSC1L1) 100224614(SETD2) 100225643(SETD8) 100225647(SETD1B) 100225827(SUV39H2) 100226399(MLL5) 100226728(EZH2) 100226907 100227122 100227193(MLL3) 100227472(EZH1) 100229714 100231049(MLL) 100231131(SETDB2) 100231651(SETDB1)
FAB: 
101805731(SUV420H1) 101806346(KMT2C) 101806838(EHMT1) 101807043(WHSC1L1) 101807375(SETD7) 101807609(DOT1L) 101809240(EZH2) 101811414(EZH1) 101812652(SETD1B) 101812878(KMT2E) 101812936(SETDB2) 101813052 101813917(KMT2A) 101814584 101814785(SETD2) 101814945(WHSC1) 101815424(NSD1) 101816158(SUV39H2) 101818086(KMT2D) 101819907(ASH1L) 101821143(SETD8)
PHI: 
102099277(KMT2C) 102099526(EHMT1) 102099930(EZH2) 102100454(KMT2D) 102101098(NSD1) 102101563(SETDB1) 102102011(SUV420H1) 102103515(KMT2A) 102103576(EZH1) 102104074(SETDB2) 102104727(WHSC1L1) 102105181(SETMAR) 102106085 102106186(SETD7) 102106397(SETD2) 102106962 102108338(KMT2E) 102108358(DOT1L) 102109183(SETD8) 102110616(SUV39H1) 102113028(ASH1L) 102113544(WHSC1) 102114300(SUV39H2) 102114734(SETD1B)
APLA: 
101789499(NSD1) 101790074(SETDB2) 101791765(EZH1) 101791981(SETD8) 101792888(WHSC1) 101793453(EZH2) 101794070 101794256(ASH1L) 101794756(SETDB1) 101796000(SUV39H2) 101796266(KMT2C) 101796335(WHSC1L1) 101797321 101800254(SETD7) 101802336(KMT2A) 101803072(SETD1B) 101803754(SUV420H1) 101804645(DOT1L) 101805084(KMT2E) 101805087(EHMT1) 101805218(SETD2)
FPG: 
101911291(DOT1L) 101911332(EZH2) 101911864(SETD1B) 101912073(SETDB1) 101912815(SUV39H2) 101913546(ASH1L) 101913589(WHSC1L1) 101913975(SETD2) 101914736(SETD8) 101914789(NSD1) 101915579(EZH1) 101916059(WHSC1) 101916063(EHMT1) 101916525(KMT2D) 101917176(KMT2C) 101917301(SETD7) 101917763(SETDB2) 101919912(KMT2E) 101920720 101921673(SUV420H1) 101922729(KMT2A)
FCH: 
102046441(SUV420H1) 102047191(KMT2C) 102047542(KMT2E) 102049111(KMT2D) 102051296(SETD1B) 102052374(EZH1) 102053153(SETD8) 102053248(SETD2) 102053275(DOT1L) 102053523(SETD7) 102055212(SETDB1) 102055251(NSD1) 102055395(SETDB2) 102055544(WHSC1L1) 102055584(EZH2) 102056334(SETMAR) 102056587(ASH1L) 102057247(EHMT1) 102059401(KMT2A) 102059458(SUV39H2) 102059826(WHSC1)
CLV: 
102083945(SETD1B) 102084453(KMT2A) 102084521(NSD1) 102085960(EHMT1) 102087865(SETD7) 102088543(SETDB2) 102088903(KMT2E) 102089973(SETD8) 102090497(WHSC1L1) 102090928(ASH1L) 102091143(SUV420H1) 102091442(KMT2D) 102093761(EZH2) 102094505(SETDB1) 102095738(WHSC1) 102096568(SETMAR) 102097006(EZH1) 102097756(DOT1L) 102097963(KMT2C) 102098192(SETD2) 102098917(SUV39H2)
ASN: 
102368409(DOT1L) 102368735(NSD1) 102372149(WHSC1) 102372569(EZH2) 102372997(ASH1L) 102373099(KMT2D) 102374512(SETD7) 102374916(EHMT1) 102375358(SUV39H2) 102375642(KMT2E) 102378063(SETD2) 102378568(SETD1B) 102378805(SUV39H1) 102378990(SUV420H2) 102379342(KMT2C) 102379587(SUV420H1) 102380189(SETDB2) 102381770(EHMT2) 102381990(SETMAR) 102382195 102382539(SETDB1) 102382842(SETD8) 102383438(EZH1) 102385195(WHSC1L1) 102385246(KMT2A) 102387237(SETD1A)
PSS: 
102445204 102446148(SETDB1) 102448089(SETD1B) 102448117(ASH1L) 102448836 102450225(EHMT1) 102450509(KMT2D) 102450951(SETDB2) 102453330(EZH2) 102454204(SUV39H2) 102454598(KMT2E) 102455080(DOT1L) 102455729 102455968 102456135(SUV420H1) 102457400(WHSC1L1) 102459016(KMT2C) 102460627 102460633(SETD1A) 102460966(SETD2) 102461475(NSD1) 102461649(SETD7) 102461914(SETMAR) 102462370(SUV39H1) 102463087(EZH1) 102463287(SETD8) 102463628(KMT2A) 102464028(WHSC1)
CMY: 
102929316(SETD8) 102930063(NSD1) 102931937(KMT2B) 102932650(EZH2) 102932781(SETDB2) 102933355(KMT2E) 102933671(EHMT1) 102934538(EZH1) 102934693(SETD1B) 102937004(SETD1A) 102937045(SUV39H2) 102937828(SETDB1) 102937831(SUV39H1) 102940729(WHSC1) 102941272(KMT2A) 102942170(SETMAR) 102943205(SETD7) 102943320(WHSC1L1) 102943662(ASH1L) 102943895(DOT1L) 102944171 102946000(SUV420H1) 102947543(SETD2) 102948345(KMT2C)
ACS: 
XLA: 
100037174(suv39h2) 100158384(setd8) 398318(mp36) 398711(setdb2) 399174(ezh2-a) 431943(suv39h1) 431996(whsc1) 432147(setdb1) 444204(suv420h1-a) 447454(setd1b) 495826(suv420h1-b) 779432(suv420h2)
XTR: 
100038141(suv420h1) 100124713(ehmt1) 100124743(setdb2) 100125213(whsc1) 100135006(kmt2a) 100135741(setmar) 100144721(kmt2b) 100145675(nsd1) 100145748 100216035(whsc1l1) 100484992(ehmt2) 100486829(kmt2c) 100487270(setd1a) 100490309(setdb1) 100492810 100493532(ezh1) 100494109(kmt2d) 100497594(dot1l) 549262(suv39h2) 550047(ezh2) 613102(setd7) 779539(kmt2e) 780106(setd1b) 780276(setd8)
DRE: 
100000709(whsc1) 100004770(setd8b) 100005761(ehmt1a) 100006350(whsc1l1) 325395(kmt2e) 326906(suv39h1b) 335153(setdb2) 402830(ehmt1b) 436729(setd7) 445198(suv39h1a) 556086(nsd1a) 556535(setd1a) 557048(kmt2a) 559945(dot1l) 560793(kmt2ca) 560856(kmt2ba) 563799(ash1l) 564575(setmar) 566825(kmt2bb) 567970(setd1ba) 569041(suv420h2) 569250(ehmt2) 571274(setd1bb) 572849(suv420h1) 664754(ezh1) 751629(setd8a) 768131(setdb1b) 768133(ezh2) 794199(setd2)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102346523(NSD1) 102347272(KMT2C) 102349988(KMT2E) 102350182(SETD7) 102351078(SETD1A) 102351844(DOT1L) 102351913 102354014(KMT2D) 102354331 102355801(SETD8) 102356699(SETDB1) 102357046(KMT2A) 102357247 102357304(SUV420H1) 102359121(SETD2) 102359445(EHMT2) 102359965(WHSC1L1) 102360554 102361297(EHMT1) 102361454(EZH2) 102363172(SETD1B) 102363237(WHSC1) 102363588(SETDB2) 102364190(EZH1) 102366478(SETMAR) 102367246(ASH1L)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
100577280 100577330 100578450 408716(trx) 409098(egg) 411070(GB18935) 411466(GB12881) 411985(GB15744) 412027(pr-set7) 413388(GB18236) 552235(E(z)) 685996(Su(var)3-9) 725514 727238(ash1)
NVI: 
100113526(E(z)) 100114564 100116149(Mes-4) 100116648(Dot1l) 100116736(SUV39H1) 100120014(Setdb1) 100120205(Trr) 100121025(Setd1a) 100121084(Ehmt1) 100123008 100123115(Set2) 100123305(ash1) 100679733
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG02629(Cbr-set-4) CBG03979 CBG03980 CBG04290 CBG10210 CBG10211 CBG10214 CBG10216 CBG10271 CBG11099(Cbr-mes-2) CBG12017(Cbr-lin-59) CBG13569(Cbr-set-23) CBG16281 CBG16282 CBG18157(Cbr-met-2) CBG18244(Cbr-set-16) CBG19678(Cbr-set-1)
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
AT1G02580(MEA) AT1G17770(SUVH7) AT1G73100(SUVH3) AT2G22740(SUVH6) AT2G23380(CLF) AT2G24740(SDG21) AT2G33290(SUVH2) AT2G35160(SUVH5) AT2G44150(ASHH3) AT3G59960(ASHH4) AT4G02020(SWN) AT4G13460(SUVH9) AT5G04940(SUVH1) AT5G13960(SUVH4)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
MTR: 
CAM: 
FVE: 
CSV: 
RCU: 
POP: 
POPTR_0001s07390g(POPTRDRAFT_708413) POPTR_0002s07930g(POPTRDRAFT_551416) POPTR_0002s19670g(POPTRDRAFT_552533) POPTR_0002s23890g POPTR_0002s23900g(POPTRDRAFT_409038) POPTR_0003s08130g POPTR_0003s16130g POPTR_0003s18740g(POPTRDRAFT_758229) POPTR_0005s18340g(POPTRDRAFT_818400) POPTR_0005s20470g POPTR_0006s02840g POPTR_0007s00210g(POPTRDRAFT_562064) POPTR_0007s10830g(POPTRDRAFT_719252) POPTR_0008s17320g(POPTRDRAFT_419224) POPTR_0010s07480g(POPTRDRAFT_229952) POPTR_0014s11520g(POPTRDRAFT_731686) POPTR_0014s14090g(POPTRDRAFT_246290) POPTR_0016s02600g(POPTRDRAFT_255095) POPTR_0017s00510g POPTR_0019s11770g(POPTRDRAFT_574323)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0811300-01(Os01g0811300) Os01t0927000-01(Os01g0927000) Os03t0307800-01(Os03g0307800) Os03t0320400-01(Os03g0320400) Os04t0544100-01(Os04g0544100) Os05t0490700-01(Os05g0490700) Os06t0275500-01(Os06g0275500) Os07t0435900-01(Os07g0435900) Os08t0400000-01(Os08g0400000) Os08t0400200-00(Os08g0400200) Os08t0565700-01(Os08g0565700) Os09t0307800-01(Os09g0307800) Os09t0362900-01(Os09g0362900) Os11t0131600-00(Os11g0131600) Os11t0602200-01(Os11g0602200) Os12t0128450-00(Os12g0128450)
OBR: 
BDI: 
SBI: 
SORBI_01g037450(SORBIDRAFT_01g037450) SORBI_02g006620(SORBIDRAFT_02g006620) SORBI_02g010210(SORBIDRAFT_02g010210) SORBI_02g020844(SORBIDRAFT_02g020844) SORBI_02g022936(SORBIDRAFT_02g022936) SORBI_03g037660(SORBIDRAFT_03g037660) SORBI_03g044580(SORBIDRAFT_03g044580) SORBI_04g025725(SORBIDRAFT_04g025725) SORBI_04g033260(SORBIDRAFT_04g033260) SORBI_06g001340(SORBIDRAFT_06g001340) SORBI_06g024160(SORBIDRAFT_06g024160) SORBI_07g019816(SORBIDRAFT_07g019816) SORBI_07g019830(SORBIDRAFT_07g019830) SORBI_07g019850(SORBIDRAFT_07g019850) SORBI_07g019860(SORBIDRAFT_07g019860) SORBI_07g019863(SORBIDRAFT_07g019863) SORBI_07g023560(SORBIDRAFT_07g023560) SORBI_08g001570(SORBIDRAFT_08g001570) SORBI_09g019060(SORBIDRAFT_09g019060) SORBI_09g024010(SORBIDRAFT_09g024010) SORBI_10g004560(SORBIDRAFT_10g004560)
ZMA: 
100194312 100273541 100280164(sdg101) 100282875 100382441 541954(mez1) 541955(mez3) 541980(sdg113) 542085(cl3507_2a) 542089(sdg118) 542090(SET104) 542102 542659(mez2) 542662(sdg110a)
SITA: 
ATR: 
s00002p00188950(AMTR_s00002p00188950) s00002p00271340(AMTR_s00002p00271340) s00008p00103090(AMTR_s00008p00103090) s00008p00104700(AMTR_s00008p00104700) s00008p00186080(AMTR_s00008p00186080) s00017p00244380(AMTR_s00017p00244380) s00019p00119370(AMTR_s00019p00119370) s00035p00184080(AMTR_s00035p00184080) s00039p00046970(AMTR_s00039p00046970) s00045p00168580(AMTR_s00045p00168580) s00045p00224440(AMTR_s00045p00224440) s00069p00076340(AMTR_s00069p00076340) s00081p00153110(AMTR_s00081p00153110) s00095p00147870(AMTR_s00095p00147870)
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OSTLU_18587(SDG3502)
OTA: 
MIS: 
MPP: 
CSL: 
CVR: 
CME: 
GSL: 
CCP: 
SCE: 
YDR440W(DOT1) YHR119W(SET1) YJL168C(SET2)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0B07030(NCAS0B07030) NCAS_0F01220(NCAS0F01220) NCAS_0I02880(NCAS0I02880)
NDI: 
NDAI_0B00260(NDAI0B00260) NDAI_0B04360(NDAI0B04360) NDAI_0H01750(NDAI0H01750)
TPF: 
TPHA_0A02720(TPHA0A02720) TPHA_0D02550(TPHA0D02550) TPHA_0I01480(TPHA0I01480)
TBL: 
TBLA_0C05500(TBLA0C05500) TBLA_0D01440(TBLA0D01440) TBLA_0E03030(TBLA0E03030) TBLA_0J01040(TBLA0J01040)
TDL: 
TDEL_0A04190(TDEL0A04190) TDEL_0B05100(TDEL0B05100) TDEL_0G02090(TDEL0G02090)
KAF: 
KAFR_0F00700(KAFR0F00700) KAFR_0F01770(KAFR0F01770) KAFR_0I00880(KAFR0I00880)
DHA: 
PIC: 
PGU: 
LEL: 
CAL: 
CaO19.13430(SET1) CaO19.1755(SET2) CaO19.6009(SET1) CaO19.7402(DOT1) CaO19.9324(SET2)
CTP: 
CDU: 
COT: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
MGR: 
FGR: 
NHE: 
TRE: 
VAL: 
SSL: 
BFU: 
ANI: 
AFM: 
AOR: 
AOR_1_1110184(AO090009000660) AOR_1_176084(AO090020000101) AOR_1_4154(AO090003000002) AOR_1_500074(AO090038000300) AOR_1_578094(AO090120000327)
ANG: 
ANI_1_1490164(An18g06840) ANI_1_1828074(An08g03380) ANI_1_2518094(An11g09860) ANI_1_296084(An09g02720) ANI_1_476104(An12g03880) ANI_1_490154(An17g01825)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
ZTR: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
PPL: 
LBC: 
MPR: 
CCI: 
SCM: 
UMA: 
MGL: 
PGR: 
EHE: 
NCE: 
MBR: 
DDI: 
DPP: 
DFA: 
ACAN: 
PFA: 
PFD: 
PFH: 
PYO: 
PCB: 
PBE: 
PKN: 
PVX: 
PCY: 
TAN: 
TPV: 
BBO: 
BBOV_IV004680(23.m06513)
BEQ: 
CPV: 
PTM: 
PTI: 
TPS: 
PIF: 
NGD: 
EHX: 
GTT: 
NGR: 
TVA: 
GLA: 
 » show all
Taxonomy
Reference
1  [PMID:5484460]
  Authors
Paik WK, Kim S.
  Title
Solubilization and partial purification of protein methylase 3 from calf thymus nuclei.
  Journal
J. Biol. Chem. 245 (1970) 6010-5.
  Organism
Bos taurus
Reference
2  [PMID:391266]
  Authors
Venkatesan M, McManus IR.
  Title
Partial purification and characterization of a protein lysine methyltransferase from plasmodia of Physarum polycephalum.
  Journal
Biochemistry. 18 (1979) 5365-71.
  Organism
Physarum polycephalum
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9055-08-7

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