| Entry |
|
|---|
| Name |
protein-histidine N-methyltransferase;
protein methylase IV;
protein (histidine) methyltransferase;
actin-specific histidine methyltransferase;
S-adenosyl methionine:protein-histidine N-methyltransferase |
|---|
| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
 |
|---|
| Sysname |
S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase |
|---|
| Reaction(IUBMB) |
S-adenosyl-L-methionine + protein L-histidine =
S-adenosyl-L-homocysteine + protein Ntau-methyl-L-histidine
[RN:R02627] |
|---|
| Reaction(KEGG) |
R02627
 |
|---|
| Substrate |
S-adenosyl-L-methionine [CPD:C00019];
protein L-histidine [CPD:C00615] |
|---|
| Product |
S-adenosyl-L-homocysteine [CPD:C00021];
protein Ntau-methyl-L-histidine |
|---|
| Comment |
Highly specific for histidine residues, for example, in actin. |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3801515]
Vijayasarathy C, Rao BS.
Partial purification and characterisation of
S-adenosylmethionine:protein-histidine N-methyltransferase from
rabbit skeletal muscle.
Biochim. Biophys. Acta. 923 (1987) 156-65.
Oryctolagus cuniculus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 2.1.1.85
IUBMB Enzyme Nomenclature: 2.1.1.85
ExPASy - ENZYME nomenclature database: 2.1.1.85
BRENDA, the Enzyme Database: 2.1.1.85
CAS: 108022-17-9 |
|---|
