KEGG   ENZYME: 2.1.1.85Help
Entry
EC 2.1.1.85                 Enzyme                                 

Name
protein-histidine N-methyltransferase;
protein methylase IV;
protein (histidine) methyltransferase;
actin-specific histidine methyltransferase;
S-adenosyl methionine:protein-histidine N-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein Ntau-methyl-L-histidine [RN:R02627]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
protein L-histidine [CPD:C00615]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
protein Ntau-methyl-L-histidine
Comment
Highly specific for histidine residues, for example, in actin.
History
EC 2.1.1.85 created 1989
Orthology
K18803  
protein-histidine N-methyltransferase
Genes
SCE: 
YIL110W(HPM1)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0B06390(NCAS0B06390)
NDI: 
NDAI_0B03680(NDAI0B03680)
TPF: 
TPHA_0F01200(TPHA0F01200)
TBL: 
TBLA_0G02490(TBLA0G02490)
TDL: 
TDEL_0C04020(TDEL0C04020)
KAF: 
KAFR_0J01520(KAFR0J01520)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
NTE: 
NEUTE1DRAFT90219(NEUTE1DRAFT_90219)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_104034(AO090103000050)
ANG: 
ANI_1_1174144(An16g08730)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
SHS: 
HIR: 
ADL: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT123080(AGABI1DRAFT_123080)
ABV: 
AGABI2DRAFT225922(AGABI2DRAFT_225922)
CPUT: 
SLA: 
UMA: 
PFP: 
MGL: 
PGR: 
WSE: 
WIC: 
 » show all
Taxonomy
Reference
1  [PMID:3801515]
  Authors
Vijayasarathy C, Rao BS.
  Title
Partial purification and characterisation of S-adenosylmethionine:protein-histidine N-methyltransferase from rabbit skeletal muscle.
  Journal
Biochim. Biophys. Acta. 923 (1987) 156-65.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
108022-17-9

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