KEGG   ENZYME: 2.1.1.86Help
Entry
EC 2.1.1.86                 Enzyme                                 
Name
tetrahydromethanopterin S-methyltransferase;
tetrahydromethanopterin methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase
Reaction(IUBMB)
5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate [RN:R04347]
Reaction(KEGG)
Substrate
5-methyl-5,6,7,8-tetrahydromethanopterin [CPD:C04488];
2-mercaptoethanesulfonate [CPD:C03576]
Product
5,6,7,8-tetrahydromethanopterin [CPD:C01217];
2-(methylthio)ethanesulfonate [CPD:C03920]
Comment
Involved in the formation of methane from CO in Methanobacterium thermoautotrophicum. Methanopterin is a pterin analogue. The reaction involves the export of one or two sodium ions in Archaea.
Pathway
Methane metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K00577  
tetrahydromethanopterin S-methyltransferase subunit A
K00578  
tetrahydromethanopterin S-methyltransferase subunit B
K00579  
tetrahydromethanopterin S-methyltransferase subunit C
K00580  
tetrahydromethanopterin S-methyltransferase subunit D
K00581  
tetrahydromethanopterin S-methyltransferase subunit E
K00582  
tetrahydromethanopterin S-methyltransferase subunit F
K00583  
tetrahydromethanopterin S-methyltransferase subunit G
K00584  
tetrahydromethanopterin S-methyltransferase subunit H
Genes
DAR: 
DTI: 
MCH: 
HMC: 
MAG: 
DSY: 
DHD: 
DDH: 
DKU: 
TJR: 
DOR: 
Desor_0411
DMI: 
Desmer_0447
DED: 
DHBDCA_p634
DEC: 
DCF50_p692
AWO: 
Awo_c07520(mttA2)
TOC: 
Toce_1535
ACA: 
ACP_1207
LFC: 
LFE_1243
LFI: 
LFML04_0654
MJA: 
MJ_0847 MJ_0848 MJ_0849 MJ_0850 MJ_0851 MJ_0852(mtrF) MJ_0853 MJ_0854
MFE: 
Mefer_0939 Mefer_0940 Mefer_0941 Mefer_0942 Mefer_0943 Mefer_0944 Mefer_0945 Mefer_0946
MVU: 
Metvu_0150 Metvu_0151 Metvu_0152 Metvu_0153 Metvu_0154 Metvu_0155(mtrF) Metvu_0156 Metvu_0157
MFS: 
MFS40622_1307 MFS40622_1308 MFS40622_1309 MFS40622_1310 MFS40622_1311 MFS40622_1312 MFS40622_1313 MFS40622_1314
MIF: 
Metin_0273 Metin_0274 Metin_0275 Metin_0276 Metin_0277 Metin_0278 Metin_0279 Metin_0280
MIG: 
Metig_1238 Metig_1239 Metig_1240 Metig_1241 Metig_1242 Metig_1243 Metig_1244 Metig_1245
MMP: 
MMP1560(mtrE) MMP1561(mtrD) MMP1562(mtrC) MMP1563(mtrB) MMP1564(mtrA) MMP1565(or900) MMP1566(mtrG) MMP1567(mtrH)
MMQ: 
MmarC5_0009 MmarC5_0010 MmarC5_0011 MmarC5_0012 MmarC5_0013 MmarC5_0014 MmarC5_0015 MmarC5_0016
MMX: 
MmarC6_1103 MmarC6_1104 MmarC6_1105 MmarC6_1106 MmarC6_1107 MmarC6_1108 MmarC6_1109 MmarC6_1110
MMZ: 
MmarC7_0807 MmarC7_0808 MmarC7_0809 MmarC7_0810 MmarC7_0811 MmarC7_0812 MmarC7_0813 MmarC7_0814
MMD: 
GYY_08650 GYY_08655 GYY_08660 GYY_08665 GYY_08670 GYY_08680 GYY_08685 GYY_08690
MAE: 
Maeo_1269 Maeo_1270 Maeo_1271 Maeo_1272 Maeo_1273 Maeo_1274 Maeo_1275 Maeo_1276
MVN: 
Mevan_0873 Mevan_0874 Mevan_0875 Mevan_0876 Mevan_0877 Mevan_0878 Mevan_0879 Mevan_0880
MVO: 
Mvol_1129 Mvol_1130 Mvol_1131 Mvol_1132 Mvol_1133 Mvol_1134 Mvol_1135 Mvol_1136
MOK: 
Metok_0948 Metok_0949 Metok_0950 Metok_0951 Metok_0952 Metok_0953 Metok_0954 Metok_0955
MAC: 
MA0269(mtrH) MA0270(mtrG) MA0271(mtrF) MA0272(mtrA) MA0273(mtrB) MA0274(mtrC) MA0275(mtrD) MA0276(mtrE) MA1804(mtxH) MA1805(mtxA)
MBA: 
Mbar_A0410 Mbar_A1255 Mbar_A1256 Mbar_A1257 Mbar_A1258 Mbar_A1259 Mbar_A1260 Mbar_A1261 Mbar_A1262 Mbar_A1713 Mbar_A2072 Mbar_A2073
MMA: 
MM_0255 MM_0256 MM_1540 MM_1541 MM_1542(mtrF) MM_1543 MM_1544 MM_1545 MM_1546 MM_1547 MM_2251
MMAZ: 
MmTuc01_0261 MmTuc01_0262 MmTuc01_1605 MmTuc01_1606 MmTuc01_1607 MmTuc01_1608 MmTuc01_1609 MmTuc01_1610 MmTuc01_1611 MmTuc01_1612 MmTuc01_2304
MBU: 
Mbur_1518 Mbur_1519 Mbur_1520(mtrF) Mbur_1521 Mbur_1522 Mbur_1523 Mbur_1524 Mbur_1525 Mbur_2244
MMH: 
Mmah_0402 Mmah_0403 Mmah_1285 Mmah_1776 Mmah_1777 Mmah_1778 Mmah_1779 Mmah_1780 Mmah_1781 Mmah_1782 Mmah_1783
MEV: 
Metev_1386 Metev_1388 Metev_2016 Metev_2017 Metev_2018 Metev_2019 Metev_2020 Metev_2021 Metev_2022 Metev_2023
MZH: 
Mzhil_0753 Mzhil_0754 Mzhil_1717 Mzhil_1718 Mzhil_1719 Mzhil_1720 Mzhil_1721 Mzhil_1722 Mzhil_1723 Mzhil_1724
MPY: 
Mpsy_0233 Mpsy_2182 Mpsy_2183 Mpsy_2184 Mpsy_2185 Mpsy_2186 Mpsy_2187 Mpsy_2188 Mpsy_2189
MHZ: 
Metho_0912 Metho_2089 Metho_2090 Metho_2091 Metho_2092 Metho_2093 Metho_2094 Metho_2095 Metho_2096
MTP: 
Mthe_1378 Mthe_1379 Mthe_1380(mtrF) Mthe_1381 Mthe_1382 Mthe_1383 Mthe_1384 Mthe_1385 Mthe_1654
MCJ: 
MCON_1068(mtrH) MCON_1069(mtrG) MCON_1070(mtrF) MCON_1071(mtrA) MCON_1072(mtrB) MCON_1073(mtrC) MCON_1074(mtrD) MCON_1075(mtrE) MCON_2872 MCON_2873
MHI: 
Mhar_1269 Mhar_1473 Mhar_2090 Mhar_2091 Mhar_2092 Mhar_2093 Mhar_2094 Mhar_2095 Mhar_2096 Mhar_2097
MHU: 
Mhun_2168 Mhun_2169 Mhun_2170 Mhun_2171 Mhun_2172 Mhun_2173(mtrF) Mhun_2174 Mhun_2175
MLA: 
Mlab_1553 Mlab_1554 Mlab_1555(mtrF) Mlab_1556 Mlab_1557 Mlab_1558 Mlab_1559 Mlab_1560
MEM: 
Memar_0605 Memar_0606 Memar_0607(mtrF) Memar_0608 Memar_0609 Memar_0610 Memar_0611 Memar_0612
MBG: 
BN140_1739(mtrE) BN140_1740(mtrD) BN140_1741(mtrC) BN140_1742 BN140_1743(mtrA) BN140_1744(mtrF) BN140_1745 BN140_1746(mtrH)
MPI: 
Mpet_2407 Mpet_2408 Mpet_2409 Mpet_2410 Mpet_2411 Mpet_2412 Mpet_2413 Mpet_2414 Mpet_2555
MBN: 
Mboo_0566 Mboo_0567 Mboo_0568(mtrF) Mboo_0569 Mboo_0570 Mboo_0571 Mboo_0572 Mboo_0573 Mboo_1043
MFO: 
Metfor_2614 Metfor_2615 Metfor_2616 Metfor_2617 Metfor_2618 Metfor_2619 Metfor_2620 Metfor_2621
MPL: 
Mpal_2310 Mpal_2311 Mpal_2312 Mpal_2313 Mpal_2314 Mpal_2315(mtrF) Mpal_2316 Mpal_2317
MPD: 
MCP_0539(mtrE) MCP_0540(mtrD) MCP_0541(mtrC) MCP_0542(mtrB) MCP_0543(mtrA-1) MCP_0545(mtrG) MCP_0546(mtrH) MCP_0678(mtrA-2)
MEZ: 
Mtc_0936(mtrE) Mtc_0937(mtrD) Mtc_0938(mtrC) Mtc_0939(mtrB) Mtc_0940(mtrA-1) Mtc_0941(mtrF) Mtc_0942(mtrG) Mtc_0943(mtrH) Mtc_0962(mtrA-2)
RCI: 
RCIX2064(mtrE) RCIX2065(mtrD) RCIX2066(mtrC) RCIX2067(mtrB) RCIX2068(mtrA-1) RCIX2069(mtrA-2) RCIX2070(mtrG) RCIX2071(mtrH)
MTH: 
MTH1062 MTH1156 MTH1157 MTH1158(mtrF) MTH1159 MTH1160 MTH1161 MTH1162 MTH1163
MMG: 
MTBMA_c14500 MTBMA_c15400(mtrH) MTBMA_c15410(mtrG) MTBMA_c15420(mtrF) MTBMA_c15430(mtrA) MTBMA_c15440(mtrB) MTBMA_c15450(mtrC1) MTBMA_c15460(mtrD) MTBMA_c15470(mtrE)
MST: 
Msp_0300(mtrE) Msp_0301(mtrD) Msp_0302(mtrC) Msp_0303(mtrB) Msp_0304(mtrA) Msp_0305(mtrF) Msp_0306(mtrG) Msp_0307(mtrH)
MSI: 
Msm_0627 Msm_1007 Msm_1008 Msm_1009(mtrF) Msm_1010 Msm_1011 Msm_1012 Msm_1013 Msm_1014
MRU: 
mru_0441(mtrA2) mru_1916(mtrH) mru_1917(mtrG) mru_1918(mtrF) mru_1919(mtrA1) mru_1920(mtrB) mru_1921(mtrC) mru_1922(mtrD) mru_1923(mtrE)
MEL: 
Metbo_0354 Metbo_0355 Metbo_0356 Metbo_0357 Metbo_0358 Metbo_0359 Metbo_0360 Metbo_0361
MEW: 
MSWAN_2048 MSWAN_2049 MSWAN_2050 MSWAN_2051 MSWAN_2052 MSWAN_2053 MSWAN_2054 MSWAN_2055
MFV: 
Mfer_0072 Mfer_0776 Mfer_0777 Mfer_0778 Mfer_0779 Mfer_0780 Mfer_0781 Mfer_0782 Mfer_0783
MKA: 
MK0656(MtrE) MK0657(MtrD) MK0658(MtrC) MK0659(MtrB) MK0660(MtrA) MK0661(MtrG) MK0662(MtrH) MK1485(MtrF)
AFU: 
AF0009(mtr)
FPL: 
Ferp_0136 Ferp_1749
SMR: 
Smar_0413
SHC: 
Shell_0390
IAG: 
Igag_0398
THG: 
TCELL_0694
NMR: 
Nmar_1747
NIR: 
NSED_09300
NKR: 
NKOR_09280
CSY: 
CENSYa_1432
NGA: 
Ngar_c18160
KCR: 
Kcr_0196
 » show all
Taxonomy
Reference
1  [PMID:3085670]
  Authors
Sauer FD.
  Title
Tetrahydromethanopterin methyltransferase, a component of the methane synthesizing complex of Methanobacterium thermoautotrophicum.
  Journal
Biochem. Biophys. Res. Commun. 136 (1986) 542-7.
  Organism
Methanobacterium thermoautotrophicum [GN:mth]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
103406-60-6
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