KEGG   ENZYME: 2.1.3.1Help
Entry
EC 2.1.3.1                  Enzyme                                 

Name
methylmalonyl-CoA carboxytransferase;
transcarboxylase;
methylmalonyl coenzyme A carboxyltransferase;
methylmalonyl-CoA transcarboxylase;
oxalacetic transcarboxylase;
methylmalonyl-CoA carboxyltransferase;
methylmalonyl-CoA carboxyltransferase;
(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase;
(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxytransferase carboxytransferase [incorrect]
Class
Transferases;
Transferring one-carbon groups;
Carboxy- and carbamoyltransferases
BRITE hierarchy
Sysname
(S)-methylmalonyl-CoA:pyruvate carboxytransferase
Reaction(IUBMB)
(S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate [RN:R00930]
Reaction(KEGG)
R00930;
(other) R00353
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Substrate
(S)-methylmalonyl-CoA [CPD:C00683];
pyruvate [CPD:C00022]
Product
propanoyl-CoA [CPD:C00100];
oxaloacetate [CPD:C00036]
Comment
A biotinyl-protein, containing cobalt and zinc.
History
EC 2.1.3.1 created 1961
Pathway
Propanoate metabolism
Orthology
K03416  
methylmalonyl-CoA carboxyltransferase 5S subunit
K17489  
methylmalonyl-CoA carboxyltransferase 12S subunit
K17490  
methylmalonyl-CoA carboxyltransferase 1.3S subunit
Genes
GBM: 
GEM: 
PPD: 
DTO: 
SRI: 
MHG: 
CEF: 
CDI: 
CDP: 
CDH: 
CDT: 
CDE: 
CDR: 
CDA: 
CDZ: 
CDB: 
CDS: 
CDD: 
CDW: 
CDV: 
CKP: 
CPU: 
CPL: 
CPG: 
CPP: 
CPK: 
CPQ: 
CPX: 
CPZ: 
COR: 
COP: 
COD: 
COS: 
COI: 
COE: 
COU: 
CUL: 
CUC: 
CUE: 
CUN: 
CUS: 
CUQ: 
CUZ: 
CAZ: 
CVT: 
COA: 
PAC: 
PAK: 
PAV: 
PAX: 
PAZ: 
PAW: 
PAD: 
PCN: 
PACC: 
PACH: 
PFR: 
PPC: 
PBO: 
PRA: 
NCA: 
ABA: 
SUS: 
CPH: 
AVE: 
 » show all
Taxonomy
Reference
1  [PMID:2920730]
  Authors
Hoffmann A, Hilpert W, Dimroth P.
  Title
The carboxyltransferase activity of the sodium-ion-translocating methylmalonyl-CoA decarboxylase of Veillonella alcalescens.
  Journal
Eur. J. Biochem. 179 (1989) 645-50.
Reference
2  [PMID:16590594]
  Authors
Swick RW, Wood HG.
  Title
THE ROLE OF TRANSCARBOXYLATION IN PROPIONIC ACID FERMENTATION.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 46 (1960) 28-41.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
9029-86-1

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