KEGG   ENZYME: 2.3.1.54Help
Entry
EC 2.3.1.54                 Enzyme                                 
Name formate C-acetyltransferase;
pyruvate formate-lyase;
pyruvic formate-lyase;
formate acetyltransferase
Class Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname acetyl-CoA:formate C-acetyltransferase
Reaction(IUBMB) acetyl-CoA + formate = CoA + pyruvate [RN:R00212]
Reaction(KEGG) R00212;
(other) R06987
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Substrate acetyl-CoA [CPD:C00024];
formate [CPD:C00058]
Product CoA [CPD:C00010];
pyruvate [CPD:C00022]
Pathway ec00620  Pyruvate metabolism
ec00640  Propanoate metabolism
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
Orthology K00656  formate C-acetyltransferase
Genes OLU: OSTLU_36056
ECO: b0823(ybiW) b0903(pflB) b3114(tdcE) b3951(pflD)
ECJ: JW0807(ybiW) JW0886(pflB) JW3923(pflD) JW5522(tdcE)
ECD: ECDH10B_0892(ybiW) ECDH10B_0973(pflB) ECDH10B_3288(tdcE)
     ECDH10B_4139(pflD)
EBW: BWG_0676(ybiW) BWG_0755(pflB) BWG_2822(tdcE) BWG_3619(pflD)
ECE: Z1046m Z1248(pflB) Z4466(tdcE) Z5507(pflD)
ECS: ECs0986 ECs3994 ECs4880(pflD)
ECF: ECH74115_1064(pflB2) ECH74115_4427(pflB1) ECH74115_5411(pflD)
ETW: ECSP_1007(pflB) ECSP_4086(tdcE) ECSP_5020(pflD)
EOJ: ECO26_0950(ybiW) ECO26_1029(pflB) ECO26_4219(tdcE)
     ECO26_5068(pflD)
EOI: ECO111_0891(ybiW) ECO111_0971(pflB) ECO111_3938(tdcE)
     ECO111_4776(pflD)
EOH: ECO103_0867(ybiW) ECO103_0946(pflB) ECO103_3861(tdcE)
     ECO103_4707(pflD)
ECG: E2348C_0774(ybiW) E2348C_0896(pflB) E2348C_3404(tdcE)
     E2348C_4263(pflD)
EOK: G2583_1051(ybiW) G2583_1138 G2583_3836(tdcE) G2583_4763
ECC: c0908(ybiW) c3872(tdcE) c4537 c4910(pflD)
ECP: ECP_0836 ECP_0914 ECP_3207 ECP_4164(pflD) ECP_4600
ECI: UTI89_C0826(ybiW) UTI89_C0974(pflB) UTI89_C3549(tdcE)
     UTI89_C4542(pflD) UTI89_C4964
ECV: APECO1_1270(ybiW) APECO1_15(pflB) APECO1_2293 APECO1_2516(pflD)
     APECO1_3310(tdcE)
ECX: EcHS_A0881 EcHS_A1009(pflB2) EcHS_A3302(pflB1) EcHS_A4185(pflD)
ECW: EcE24377A_0894 EcE24377A_1000(pflB2) EcE24377A_3588(pflB1)
     EcE24377A_4490(pflD)
ECM: EcSMS35_0848 EcSMS35_2218(pflB2) EcSMS35_3410(pflB1)
     EcSMS35_4398(pflD)
ECY: ECSE_0881 ECSE_0962 ECSE_3398 ECSE_4244(pflD)
ECR: ECIAI1_0862(ybiW) ECIAI1_0943(pflB) ECIAI1_3263(tdcE)
     ECIAI1_4159(pflD)
ECQ: ECED1_0787(ybiW) ECED1_0930(pflB) ECED1_3461 ECED1_3779(tdcE)
     ECED1_4656(pflD)
ECK: EC55989_0868(ybiW) EC55989_0948(pflB) EC55989_3531(tdcE)
     EC55989_4433(pflD)
ECT: ECIAI39_0800(ybiW) ECIAI39_2245(pflB) ECIAI39_3038(pflD)
     ECIAI39_3615(tdcE) ECIAI39_4211
EUM: ECUMN_1011(ybiW) ECUMN_1096(pflB) ECUMN_3598(tdcE)
     ECUMN_4482(pflD)
ECZ: ECS88_0840(ybiW) ECS88_0931(pflB) ECS88_3507(tdcE)
     ECS88_4406(pflD) ECS88_4672
ECL: EcolC_0584 EcolC_2693 EcolC_2821 EcolC_4065(pflD)
EBR: ECB_00790(ybiW) ECB_00907(pflB) ECB_02981(tdcE) ECB_03836(pflD)
EBD: ECBD_0626 ECBD_2692 ECBD_2800 ECBD_4073(pflD)
EFE: EFER_0965(ybiW) EFER_1048(pflB) EFER_1995 EFER_3812(pflD)
STY: STY0882(ybiW) STY0973(pflB) STY3423(tdcE)
STT: t1961(pflB) t2046(ybiW) t3161(tdcE)
STM: STM0843(pflF) STM0973(pflB) STM3241(tdcE) STM4114(pflD)
SPT: SPA1825(pflB) SPA1912(ybiW) SPA3110(tdcE)
SEK: SSPA1697 SSPA1782 SSPA2904
SPQ: SPAB_02545 SPAB_02655 SPAB_04044 SPAB_05097(pflD)
SEI: SPC_0840(ybiW) SPC_0972(pflB) SPC_3317(tdcE) SPC_4223(pflD)
SEC: SC0838(pflF) SC0927(pflB) SC3187(tdcE)
SEH: SeHA_C0973 SeHA_C1071(pflB2) SeHA_C3536(pflB)
SEE: SNSL254_A0911 SNSL254_A1006(pflB2) SNSL254_A3503(pflB)
     SNSL254_A4445(pflD)
SEW: SeSA_A0994 SeSA_A1086(pflB2) SeSA_A3432(pflB)
SEA: SeAg_B0884 SeAg_B0978(pflB2) SeAg_B3429(pflB)
SED: SeD_A0944 SeD_A1037(pflB2) SeD_A3599(pflB) SeD_A4519(pflD)
SEG: SG0824(pflF) SG0915(pflB) SG3138(tdcE) SG3303(pflD)
SET: SEN0789(pflF) SEN0877(pflB) SEN3082(tdcE) SEN3908(pflD)
SES: SARI_01990 SARI_02080 SARI_04378
YPE: YPO1383(pfl)
YPK: y2790(pflB)
YPA: YPA_0674
YPN: YPN_2594
YPM: YP_1210(pflB)
YPP: YPDSF_2312
YPG: YpAngola_A1946(pflB)
YPZ: YPZ3_1263(pflB)
YPS: YPTB1408(pflB)
YPI: YpsIP31758_2589(pflB)
YPY: YPK_2677
YPB: YPTS_1509
YEN: YE0339(tdcE) YE0646 YE1532(pfl)
SFL: SF0773(ybiW) SF0898(pflB) SF3154(tdcE) SF4028(pflD)
SFX: S0816(ybiW) S0962(pflB) S3366(tdcE) S3718(pflD)
SFV: SFV_0806(ybiW) SFV_0903(pflB) SFV_3155(tdcE) SFV_4020(pflD)
SSN: SSON_0805(ybiW) SSON_0904(pflB) SSON_3271(tdcE)
SBO: SBO_0713(ybiW) SBO_2189(pflB) SBO_2979(tdcE) SBO_3970(pflD)
SBC: SbBS512_E2425(pflB2) SbBS512_E2525 SbBS512_E3243(pflB1)
     SbBS512_E4437(pflD)
SDY: SDY_0764(ybiW) SDY_2358(pflB) SDY_3306(tdcE) SDY_3786(pflD)
ECA: ECA2597(pflB) ECA3768
PCT: PC1_1729 PC1_3543
PWA: Pecwa_1997 Pecwa_3461 Pecwa_3714 Pecwa_4092
ETA: ETA_21480(pflB)
EBI: EbC_14970(pflB)
PLU: plu1613(pflB)
PAY: PAU_02837(pflB)
SGL: SG0988
ENT: Ent638_1317 Ent638_1423 Ent638_3561
ENC: ECL_02750 ECL_02896 ECL_04508
ESA: ESA_01583 ESA_02441
CTU: Ctu_15080(pflB) Ctu_23350(ybiW)
KPN: KPN_00857(ybiW) KPN_00931(pflB) KPN_02292(tdcE)
KPE: KPK_2017 KPK_3553(pflD) KPK_3628(pflB) KPK_3709 KPK_4883
KPU: KP1_1816(ybiW) KP1_1902(pflB) KP1_1989(pflD) KP1_3408(tdcE)
KVA: Kvar_1911 Kvar_3372 Kvar_3445 Kvar_3521 Kvar_4520
CKO: CKO_02168 CKO_02287 CKO_03043(pflD) CKO_04514
CRO: ROD_08271(pflF) ROD_09721(pflB) ROD_37941(pflD) ROD_47631(tdcE)
SPE: Spro_1702 Spro_2642
PMR: PMI0705(pflB) PMI2716
EIC: NT01EI_2463
ETR: ETAE_0450 ETAE_0897(tdcE) ETAE_0913(pflD) ETAE_2182(pflB)
DDA: Dd703_2243
DDC: Dd586_2285
DZE: Dd1591_2345
XBO: XBJ1_0821(pflB)
XNE: XNC1_1557(pflB)
PAM: PANA_1347(pflB)
HIN: HI0180
HIT: NTHI0269(pflB)
HIP: CGSHiEE_02440
HIQ: CGSHiGG_03495
HDU: HD0990(pflB)
HAP: HAPS_0155(pflB)
HSO: HS_1136(pflB)
HSM: HSM_1041
PMU: PM0075(pflB)
MSU: MS0401(pflD)
APL: APL_1036(pflB)
APJ: APJL_1054(pflB)
APA: APP7_1092
ASU: Asuc_0207
AAP: NT05HA_0113
AAT: D11S_1949
VCH: VC1866
VCO: VC0395_A1457(pflB)
VCM: VCM66_1789(pflB)
VCJ: VCD_002496
VVU: VV1_2098
VVY: VV2342
VPA: VP0994 VPA1567
VHA: VIBHAR_01546 VIBHAR_02963
VSP: VS_1052
VEX: VEA_001156 VEA_003976
VFI: VF_1590(pflB) VF_A0142
VFM: VFMJ11_1700(pflB_1) VFMJ11_A0177(pflB_2)
VSA: VSAL_I1955(pflB)
PPR: PBPRA2750
SON: SO_2912(pflB)
SDN: Sden_2406
SFR: Sfri_2473
SAZ: Sama_1498
SBL: Sbal_2671
SBM: Shew185_2690
SBN: Sbal195_2769
SBP: Sbal223_1694
SLO: Shew_2390
SPC: Sputcn32_0208 Sputcn32_2378
SSE: Ssed_1708
SPL: Spea_1672
SHE: Shewmr4_1494
SHM: Shewmr7_1561
SHN: Shewana3_1555
SHW: Sputw3181_0427 Sputw3181_1631
SHL: Shal_2592
SWD: Swoo_2883
SWP: swp_1952
SVO: SVI_1625(pflB)
PIN: Ping_3307
TTU: TERTU_0382(pflB)
AHA: AHA_1330 AHA_1941(pflB) AHA_2856
ASA: ASA_2352(pflB)
TAU: Tola_0881 Tola_1902(pflD) Tola_2307
DNO: DNO_1334(pflB)
CVI: CV_1412(pflB)
DAR: Daro_2096
GCA: Galf_0602 Galf_1644
GSU: GSU2101
GBM: Gbem_2499
PCA: Pcar_0937 Pcar_1397
DVU: DVU2272 DVU2824
DVL: Dvul_0491 Dvul_0979
DDE: Dde_1273 Dde_3039 Dde_3055 Dde_3282
DDS: Ddes_1357 Ddes_1436
DMA: DMR_14270
DSA: Desal_0468 Desal_2091 Desal_3528
DBA: Dbac_1587 Dbac_2366
DPS: DP0616(pflD) DP1823 DP3027
DOL: Dole_0906
DAL: Dalk_1477 Dalk_1731 Dalk_2579
DAT: HRM2_49330(pflD2)
DBR: Deba_2846
RPC: RPC_1080 RPC_1163 RPC_2980
RPE: RPE_3101
NHA: Nham_0889
RCP: RCAP_rcc02211(pflD) RCAP_rcc02866(pflB)
ZMO: ZMO1570
ZMN: Za10_1639
RRU: Rru_A0903 Rru_A3000
AZL: AZL_c04440(pflD)
BAN: BA_0509(pfl)
BAR: GBAA_0509(pfl)
BAT: BAS0481
BAH: BAMEG_4097(pfl)
BAI: BAA_0570(pfl)
BAL: BACI_c05030(pflB)
BCE: BC0491
BCA: BCE_0563(pfl)
BCZ: BCZK0420(pflB)
BCR: BCAH187_A0565(pfl)
BCB: BCB4264_A0512(pfl)
BCU: BCAH820_0490(pfl)
BCG: BCG9842_B4811(pfl)
BCQ: BCQ_0537(pflB)
BCX: BCA_0528(pfl)
BCY: Bcer98_0431
BTK: BT9727_0424(pflB)
BTL: BALH_0446(pflB)
BTB: BMB171_C0434(pfl)
BWE: BcerKBAB4_0426
BLI: BL01863
BLD: BLi02132
BSE: Bsel_1991
GWC: GWCH70_3390
GYM: GYMC10_2064
AFL: Aflv_2793
SAU: SA0218(pflB)
SAV: SAV0226(pflB)
SAW: SAHV_0225(pflB)
SAH: SaurJH1_0216
SAJ: SaurJH9_0210
SAM: MW0201(pflB)
SAS: SAS0201
SAR: SAR0217
SAC: SACOL0204(pflB)
SAX: USA300HOU_0233(pfl)
SAA: SAUSA300_0220(pflB)
SAO: SAOUHSC_00187
SAE: NWMN_0162(pflB)
SAD: SAAV_0191
SAB: SAB0164
SEP: SE0214
SER: SERP2366(pflB)
SCA: Sca_2017(pflB)
SLG: SLGD_00171
LMO: lmo1406(pflB) lmo1917(pflA)
LMF: LMOf2365_1425(pfl-1) LMOf2365_1946(pfl-2)
LMH: LMHCC_0639(pflB) LMHCC_1163(pflB)
LMC: Lm4b_01415(pflB) Lm4b_01934(pflA)
LMN: LM5578_1547(pflB) LM5578_2118(pflA)
LMY: LM5923_1499(pflB) LM5923_2069(pflA)
LIN: lin1443(pflB) lin2031
LWE: lwe1422(pflB) lwe1943
LSG: lse_1323(pflB1) lse_1903(pflB3)
ESI: Exig_0607
EAT: EAT1b_2350
MCL: MCCL_0434(pflB)
PJD: Pjdr2_5252
LLA: L57408(pfl)
LLK: LLKF_0640(pfl)
LLC: LACR_0691
LLM: llmg_0629(pfl)
SPY: SPy_1849(pfl) SPy_2049(pflD)
SPZ: M5005_Spy_1569(pfl) M5005_Spy_1743(pflD)
SPM: spyM18_1912(pfl) spyM18_2110(pflD)
SPG: SpyM3_1596(pfl) SpyM3_1749(pflD)
SPS: SPs0271 SPs1747
SPH: MGAS10270_Spy1636(pfl) MGAS10270_Spy1812(pflD)
SPI: MGAS10750_Spy1628(pfl) MGAS10750_Spy1837(pflD)
SPJ: MGAS2096_Spy1594(pfl) MGAS2096_Spy1777(pflD)
SPK: MGAS9429_Spy1574(pfl) MGAS9429_Spy1752 MGAS9429_Spy1753(pflD)
SPF: SpyM50281(pfl) SpyM51706(pflD)
SPA: M6_Spy1581 M6_Spy1743
SPB: M28_Spy1557(pfl) M28_Spy1730(pflD)
SOZ: Spy49_1442(pfl) Spy49_1697c(pflD)
SPN: SP_0251 SP_0459
SPD: SPD_0235(pfl) SPD_0420(pflB)
SPR: spr0232(pflF) spr0415(pfl)
SPW: SPCG_0262(pflF) SPCG_0456(pfl)
SPX: SPG_0238 SPG_0424
SNE: SPN23F_02410(pflD) SPN23F_04320(pfl)
SPV: SPH_0369 SPH_0569(pflB)
SNM: SP70585_0313 SP70585_0532(pflB)
SJJ: SPJ_0263 SPJ_0444(pflB)
SPP: SPP_0303 SPP_0493(pflB)
SNT: SPT_0299 SPT_0498(pflB)
SNC: HMPREF0837_10567(pfl) HMPREF0837_10754
SAG: SAG0331(pflD-1) SAG1727(pflD-2)
SAN: gbs0319 gbs1772
SAK: SAK_0401 SAK_1735(pflB)
SMU: SMU.402(pfl) SMU.493(pfl2)
SMC: SmuNN2025_1479(pfl2) SmuNN2025_1558(pf1)
STC: str1657(pfl)
STL: stu1657(pfl)
STE: STER_1622
SSA: SSA_0285 SSA_0342
SSU: SSU05_0200 SSU05_0714
SSV: SSU98_0201 SSU98_0713
SSB: SSUBM407_0184(pfl) SSUBM407_1164(pflD)
SSI: SSU0191(pfl) SSU0667(pflD)
SSS: SSUSC84_0182(pfl) SSUSC84_0633(pflD)
SGO: SGO_0247(pfl) SGO_1788
SEQ: SZO_16510 SZO_18170
SEZ: Sez_0326(pfl) Sez_1808
SEU: SEQ_0391 SEQ_2106
SUB: SUB0160(pflD) SUB1568(pfl)
SDS: SDEG_0175 SDEG_1897(pfl)
SGA: GALLO_1953(pflA)
SMB: smi_1815(pfl)
LPL: lp_2598(pflB1) lp_3313(pflB2)
LPJ: JDM1_2087(pflB1) JDM1_2659(pflB2)
LSA: LSA0974(pflB)
LSL: LSL_1873(pflD)
LCA: LSEI_1410
LCB: LCABL_16340(pflB)
LCZ: LCAZH_1396
LRH: LGG_01421(pflB)
LRL: LC705_01438(pflB)
EFA: EF1613(pflB)
CAC: CA_C0980(pflB)
CPE: CPE1153(pflA)
CPF: CPF_1356(pfl)
CPR: CPR_1169(pfl)
CTC: CTC00936 CTC01449
CNO: NT01CX_0015(pflB) NT01CX_0385 NT01CX_0498 NT01CX_1220
CTH: Cthe_0505
CDF: CD0759(plfB) CD1120(dhaB1) CD3282(pflD)
CDC: CD196_0706(plfB) CD196_0973(dhaB1) CD196_3097(pflD)
CDL: CDR20291_0687(plfB) CDR20291_0951(dhaB1) CDR20291_3143(pflD)
CBO: CBO2118 CBO3183 CBO3216(pflA)
CBA: CLB_2055 CLB_3219 CLB_3252(pfl)
CBH: CLC_2060 CLC_3093 CLC_3126(pfl)
CBY: CLM_2326 CLM_3595 CLM_3627(pfl)
CBL: CLK_0644 CLK_1571 CLK_2581 CLK_2613(pfl)
CBK: CLL_A1453 CLL_A1513 CLL_A1841 CLL_A2573(pflB)
CBB: CLD_1316(pfl) CLD_1348 CLD_2523
CBI: CLJ_B2322 CLJ_B3455 CLJ_B3488(pfl)
CBT: CLH_1376 CLH_1661 CLH_2339(pflB)
CBF: CLI_2161 CLI_3322 CLI_3354(pfl)
CBE: Cbei_0315 Cbei_0705 Cbei_1009 Cbei_1011 Cbei_4061
CKL: CKL_0323 CKL_1107(pfl) CKL_3002
CKR: CKR_0275 CKR_1008 CKR_2652
CPY: Cphy_1174 Cphy_1417 Cphy_2823
CCE: Ccel_2582
CLJ: CLJU_c11830(pflB1) CLJU_c25980(pflB2) CLJU_c39830(pflB3)
CCB: Clocel_1176 Clocel_1811
AMT: Amet_0506 Amet_0584 Amet_1986 Amet_2211 Amet_3836
AOE: Clos_2398 Clos_2688
STH: STH115
SWO: Swol_1048
VPR: Vpar_0255
AFN: Acfer_0789
DSY: DSY0416 DSY3016 DSY5006
DHD: Dhaf_0366 Dhaf_1246 Dhaf_4905
DRM: Dred_0039 Dred_2750 Dred_2753 Dred_2965 Dred_3278
PTH: PTH_2436(pflD)
FMA: FMG_1495
EEL: EUBELI_20055
ERE: EUBREC_0469
BPB: bpr_I0112(pflB)
CLO: HMPREF0868_0894(pflB)
CPO: COPRO5265_1565
NTH: Nther_2476
HOR: Hore_23170
ACL: ACL_0028(pfl)
CAR: cauri_2089(pflB)
CPU: cpfrc_00251(pflB)
SCB: SCAB_10721(plfB)
JDE: Jden_1398
XCE: Xcel_1895
SKE: Sked_16330
CFL: Cfla_1721
NML: Namu_3208
AMI: Amir_2418
MAU: Micau_2388
AHE: Arch_0430
MCU: HMPREF0573_10300(pflB)
BLO: BL0951(pfl)
BLJ: BLD_0693(pflD)
BLN: Blon_1715
BLL: BLJ_0779
BAD: BAD_0992(pfl)
BLA: BLA_0967(pflB)
BLC: Balac_1083
BLT: Balat_1083
BDE: BDP_1376(pfl)
GVA: HMPREF0424_0886
SHI: Shel_17440
APV: Apar_0656
OLS: Olsu_0124 Olsu_0297 Olsu_0306 Olsu_1202
SSM: Spirs_0222 Spirs_3518 Spirs_4170
BTH: BT_2955 BT_4738
BFR: BF1339 BF4383
BFS: BF1323(pflB) BF4181(pflD)
BVU: BVU_1421 BVU_2880
PDI: BDI_0786 BDI_3392
PRU: PRU_1243(pflB) PRU_1537
PMZ: HMPREF0659_A7109(pflB)
FSU: Fisuc_1044
FNU: FN0262
LBA: Lebu_1913 Lebu_1948
STR: Sterm_1074 Sterm_1937 Sterm_2718
SMF: Smon_1058
CAA: Caka_2091
AMU: Amuc_1543
TAI: Taci_1437
CYA: CYA_0477(pflB)
CYB: CYB_0245(pflB)
TEL: tll0990
CYC: PCC7424_2838
GVI: glr3745
AMR: AM1_0439(pflB)
TLE: Tlet_1141
DDF: DEFDS_2103
DAP: Dacet_1516
MRU: mru_1519(pfl)
AFU: AF1449(pflD)
TKO: TK0289
TSI: TSIB_0631
ABI: Aboo_0169
KCR: Kcr_0517
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:4615902]
Knappe J, Blaschkowski HP, Grobner P, Schmitt T.
Pyruvate formate-lyase of Escherichia coli: the acetyl-enzyme
intermediate.
Eur. J. Biochem. 50 (1974) 253-63.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 2.3.1.54
IUBMB Enzyme Nomenclature: 2.3.1.54
ExPASy - ENZYME nomenclature database: 2.3.1.54
BRENDA, the Enzyme Database: 2.3.1.54
CAS: 9068-08-0
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