KEGG   ENZYME: 2.3.1.76Help
Entry
EC 2.3.1.76                 Enzyme                                 

Name
retinol O-fatty-acyltransferase;
retinol acyltransferase;
retinol fatty-acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:retinol O-acyltransferase
Reaction(IUBMB)
acyl-CoA + retinol = CoA + retinyl ester [RN:R02366]
Reaction(KEGG)
R02366 > R02367;
(other) R08381
Show
Substrate
acyl-CoA [CPD:C00040];
retinol [CPD:C00473]
Product
CoA [CPD:C00010];
retinyl ester [CPD:C02075]
Comment
Acts on palmitoyl-CoA and other long-chain fatty-acyl derivatives of CoA.
History
EC 2.3.1.76 created 1984
Pathway
Retinol metabolism
Orthology
K11155  
diacylglycerol O-acyltransferase 1
K11156  
diacylglycerol O-acyltransferase 2-like protein 4
Genes
HSA: 
158835(AWAT2) 8694(DGAT1)
PTR: 
464460(DGAT1) 473654(AWAT2)
PPS: 
100969745(AWAT2) 100994391(DGAT1)
GGO: 
101142898(DGAT1) 101153985(AWAT2)
PON: 
100444717(AWAT2) 100453587(DGAT1)
MCC: 
696451(AWAT2) 701489(DGAT1)
MCF: 
102121566(DGAT1) 102128700(AWAT2)
MMU: 
13350(Dgat1) 245532(Awat2)
RNO: 
302425(Awat2) 84497(Dgat1)
CGE: 
100755985(Dgat1) 100768365(Awat2)
HGL: 
101701856(Awat2) 101723650(Dgat1)
TUP: 
102474487(DGAT1) 102502982(AWAT2)
CFA: 
482093(DGAT1) 491936(AWAT2)
AML: 
FCA: 
101086879(AWAT2) 101101615(DGAT1)
PTG: 
102952284(DGAT1) 102972443(AWAT2)
BTA: 
282609(DGAT1) 521298(AWAT2)
BOM: 
102275983(AWAT2) 102277779(DGAT1)
PHD: 
102331938(AWAT2) 102333981(DGAT1)
CHX: 
100861225(DGAT1) 102177144(AWAT2)
SSC: 
100151799(AWAT2) 397118(DGAT)
CFR: 
102514200(AWAT2) 102515256(DGAT1)
BACU: 
103001320(DGAT1) 103009724(AWAT2)
LVE: 
103073062(DGAT1) 103074572(AWAT2)
ECB: 
100066473(AWAT2) 100147359(DGAT1)
MYB: 
102242085(AWAT2) 102263903(DGAT1)
MYD: 
102760049(AWAT2) 102769363(DGAT1)
PALE: 
102889573(DGAT1) 102895732(AWAT2)
MDO: 
100014456(AWAT2) 100018271(DGAT1)
SHR: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
103065772(DGAT1)
XTR: 
101730812(dgat1)
DRE: 
325875(dgat1a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
552377(mdy)
NVI: 
TCA: 
BMOR: 
PHU: 
ISC: 
CEL: 
CBR: 
BMY: 
LOA: 
TSP: 
SMM: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
AT2G19450(TAG1)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
547982(DGAT) 548005(DAGAT1) 732606(DGAT1b)
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os05t0196800-00(Os05g0196800) Os06t0563900-01(Os06g0563900)
OBR: 
BDI: 
SBI: 
SORBI_09g006110(SORBIDRAFT_09g006110) SORBI_10g022270(SORBIDRAFT_10g022270)
ZMA: 
SITA: 
ATR: 
s00036p00158260(AMTR_s00036p00158260)
SMO: 
PPP: 
VCN: 
CSL: 
CVR: 
CME: 
GSL: 
CCP: 
YLI: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1456054(AO090011000863)
ANG: 
ANI_1_1688104(An12g03600)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
ZTR: 
PFJ: 
BCOM: 
TML: 
ECU: 
EIN: 
EHE: 
NCE: 
MBR: 
DDI: 
DPP: 
DFA: 
ACAN: 
TET: 
PTI: 
TPS: 
EHX: 
GTT: 
NGR: 
 » show all
Taxonomy
Reference
1  [PMID:6826734]
  Authors
Helgerud P, Petersen LB, Norum KR.
  Title
Retinol esterification by microsomes from the mucosa of human small intestine. Evidence for acyl-Coenzyme A retinol acyltransferase activity.
  Journal
J. Clin. Invest. 71 (1983) 747-53.
  Organism
Homo sapiens
Reference
2  [PMID:7061433]
  Authors
Ross AC.
  Title
Retinol esterification by rat liver microsomes. Evidence for a fatty acyl coenzyme A: retinol acyltransferase.
  Journal
J. Biol. Chem. 257 (1982) 2453-9.
  Organism
Rattus norvegicus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
81295-48-9

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