KEGG   ENZYME: 2.3.1.80Help
Entry
EC 2.3.1.80                 Enzyme                                 

Name
cysteine-S-conjugate N-acetyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:S-substituted L-cysteine N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + an L-cysteine-S-conjugate = CoA + an N-acetyl-L-cysteine-S-conjugate [RN:R04950]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
L-cysteine-S-conjugate
Product
CoA [CPD:C00010];
N-acetyl-L-cysteine-S-conjugate
Comment
S-Benzyl-L-cysteine and, in decreasing order of activity, S-butyl-L-cysteine, S-propyl-L-cysteine, O-benzyl-L-serine and S-ethyl-L-cysteine, can act as acceptors.
History
EC 2.3.1.80 created 1984
Pathway
Glutathione metabolism
Reference
1  [PMID:6892478]
  Authors
Duffel MW, Jakoby WB.
  Title
Cysteine S-conjugate N-acetyltransferase from rat kidney microsomes.
  Journal
Mol. Pharmacol. 21 (1982) 444-8.
  Organism
Rattus norvegicus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
81725-80-6

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