| Entry |
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| Name |
citrate (Re)-synthase;
(R)-citrate synthase;
Re-citrate-synthase;
citrate oxaloacetate-lyase [(pro-3R)-CH2COO-->acetyl-CoA]
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| Class |
Transferases;
Acyltransferases;
Acyl groups converted into alkyl groups on transfer
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| Sysname |
acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-R)-carboxymethyl-forming]
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| Reaction(IUBMB) |
acetyl-CoA + H2O + oxaloacetate = citrate + CoA [RN: R00351]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
This enzyme is inactivated by oxygen and is found in some anaerobes. Its stereospecificity is opposite to that of EC 2.3.3.1, citrate (Si)-synthase.
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| Reference |
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| Authors |
Dittbrenner S, Chowdhury AA, Gottschalk G. |
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| Title |
The stereospecificity of the (R)-citrates synthase in the presence of p-chloromercuribenzoate. |
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| Journal |
Biochem. Biophys. Res. Commun. 36 (1969) 802-8. |
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| Organism |
Clostridium kluyveri, Clostridium acidi-urici |
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| Reference |
|
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| Authors |
Gottschalk G. |
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| Title |
Partial purification and some properties of the (R)-citrate synthase from Clostridium acidi-urici. |
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| Journal |
Eur. J. Biochem. 7 (1969) 301-6. |
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| Organism |
Clostridium acidi-urici |
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| Reference |
|
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| Authors |
Gottschalk G, Barker HA. |
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| Title |
Synthesis of glutamate and citrate by Clostridium kluyveri. A new type of citrate synthase. |
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| Journal |
Biochemistry. 5 (1966) 1125-33. |
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| Organism |
Clostridium kluyveri |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 9077-70-7 |
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