KEGG   ENZYME: 2.4.1.13Help
Entry
EC 2.4.1.13                 Enzyme                                 
Name
sucrose synthase;
UDPglucose-fructose glucosyltransferase;
sucrose synthetase;
sucrose-UDP glucosyltransferase;
sucrose-uridine diphosphate glucosyltransferase;
uridine diphosphoglucose-fructose glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
Reaction(IUBMB)
NDP-glucose + D-fructose = NDP + sucrose [RN:R07256]
Reaction(KEGG)
Substrate
NDP-glucose [CPD:C15541];
D-fructose [CPD:C00095]
Product
NDP [CPD:C00454];
sucrose [CPD:C00089]
Comment
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) [10].
Pathway
Starch and sucrose metabolism
Metabolic pathways
Orthology
K00695  
sucrose synthase
Genes
ATH: 
AT1G73370(SUS6) AT3G43190(SUS4) AT4G02280(SUS3) AT5G20830(SUS1) AT5G37180(SUS5) AT5G49190(SUS2)
ALY: 
GMX: 
MTR: 
CSV: 
RCU: 
POP: 
VVI: 
OSA: 
DOSA: 
Os02t0831500-01(Os02g0831500) Os03t0340500-01(Os03g0340500) Os03t0401300-01(Os03g0401300) Os04t0249500-00(Os04g0249500) Os04t0309600-01(Os04g0309600) Os06t0194900-01(Os06g0194900) Os07t0616800-01(Os07g0616800)
BDI: 
100820943 100821418 100836007 100839938 100840503 100841916
SBI: 
SORBI_01g033060(SORBIDRAFT_01g033060) SORBI_01g035890(SORBIDRAFT_01g035890) SORBI_04g038410(SORBIDRAFT_04g038410)
ZMA: 
542091(sus2) 542247(sus1) 542365(SH-1)
SMO: 
SELMODRAFT_268237(SUS)
PPP: 
PHYPADRAFT_119166 PHYPADRAFT_186437 PHYPADRAFT_188513 PHYPADRAFT_197679
NOC: 
Noc_3068
NHL: 
Nhal_3940
NWA: 
Nwat_3123
TGR: 
Tgr7_0177
AFE: 
Lferr_1268
AFR: 
AFE_1552
ACU: 
Atc_1727
AFI: 
Acife_1678
NEU: 
NE1214(ss2)
NET: 
Neut_1079
NMU: 
Nmul_A2266
DAK: 
DaAHT2_1336
DIN: 
Selin_2399
TEL: 
tlr1047
CYC: 
PCC7424_3776
CYN: 
Cyan7425_1752 Cyan7425_3916
AMR: 
AM1_6048
DSL: 
Dacsa_2708
HAO: 
PCC7418_2272
GLP: 
Glo7428_0408 Glo7428_4260
GVI: 
gvip490(spsA)
ANA: 
all1059 all4985(susA)
NPU: 
Npun_F1876 Npun_F4951
NOS: 
Nos7107_1514 Nos7107_2802
NOP: 
Nos7524_2894 Nos7524_5556
AVA: 
Ava_2283 Ava_3753
ANB: 
ANA_C11946(susA)
ACY: 
Anacy_1886 Anacy_4232
NAZ: 
Aazo_0215
CSG: 
Cylst_0728 Cylst_1832
CALO: 
Cal7507_2215 Cal7507_5465
CALT: 
Cal6303_2136
RIV: 
Riv7116_3519
GEI: 
GEI7407_2715
OAC: 
Oscil6304_3602
ONI: 
Osc7112_4334
PSEU: 
Pse7367_0339
CEP: 
Cri9333_2952
MIC: 
Mic7113_2737 Mic7113_3751
ARP: 
NIES39_O01860
CTHE: 
Chro_5323
PLP: 
Ple7327_0671 Ple7327_2003
SCS: 
Sta7437_0897
DAP: 
Dacet_2944
 » show all
Taxonomy
Reference
1
  Authors
Avigad, G. and Milner, Y.
  Title
UDP-glucose:fructose transglucosylase from sugar beet roots.
  Journal
Methods Enzymol. 8 (1966) 341-345.
Reference
2  [PMID:14367373]
  Authors
CARDINI CE, LELOIR LF, CHIRIBOGA J.
  Title
The biosynthesis of sucrose.
  Journal
J. Biol. Chem. 214 (1955) 149-55.
  Organism
Pseudomonas saccharophila
Reference
3  [PMID:4624446]
  Authors
Delmer DP.
  Title
The purification and properties of sucrose synthetase from etiolated Phaseolus aureus seedlings.
  Journal
J. Biol. Chem. 247 (1972) 3822-8.
  Organism
Phaseolus aureus
Reference
4  [PMID:5941994]
  Authors
Murata T, Sugiyama T, Minamikawa T, Akazawa T.
  Title
Enzymic mechanism of starch synthesis in ripening rice grains. 3. Mechanism of the sucrose-starch conversion.
  Journal
Arch. Biochem. Biophys. 113 (1966) 34-44.
  Organism
Oryza sativa
Reference
5  [PMID:10050318]
  Authors
Nakai T, Konishi T, Zhang XQ, Chollet R, Tonouchi N, Tsuchida T, Yoshinaga F, Mori H, Sakai F, Hayashi T.
  Title
An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11.
  Journal
Plant. Cell. Physiol. 39 (1998) 1337-41.
  Organism
Vigna radiata
Reference
6  [PMID:10592030]
  Authors
Porchia AC, Curatti L, Salerno GL.
  Title
Sucrose metabolism in cyanobacteria: sucrose synthase from Anabaena sp. strain PCC 7119 is remarkably different from the plant enzymes with respect to substrate affinity and amino-terminal sequence.
  Journal
Planta. 210 (1999) 34-40.
  Organism
Anabaena sp.
Reference
7  [PMID:16653008]
  Authors
Ross HA, Davies HV.
  Title
Purification and Characterization of Sucrose Synthase from the Cotyledons of Vicia faba L.
  Journal
Plant. Physiol. 100 (1992) 1008-1013.
  Organism
Vicia fava
Reference
8  [PMID:16661094]
  Authors
Silvius JE, Snyder FW.
  Title
Comparative Enzymic Studies of Sucrose Metabolism in the Taproots and Fibrous Roots of Beta vulgaris L.
  Journal
Plant. Physiol. 64 (1979) 1070-1073.
  Organism
Beta vulgaris
Reference
9  [PMID:10845453]
  Authors
Tanase K, Yamaki S.
  Title
Purification and characterization of two sucrose synthase isoforms from Japanese pear fruit.
  Journal
Plant. Cell. Physiol. 41 (2000) 408-14.
  Organism
Pyrus serotina
Reference
10 [PMID:12773636]
  Authors
Baroja-Fernandez E, Munoz FJ, Saikusa T, Rodriguez-Lopez M, Akazawa T, Pozueta-Romero J.
  Title
Sucrose synthase catalyzes the de novo production of ADPglucose linked to starch biosynthesis in heterotrophic tissues of plants.
  Journal
Plant. Cell. Physiol. 44 (2003) 500-9.
  Organism
Hordeum vulgare
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9030-05-1
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