KEGG ENZYME: 2.6.1.18

ENZYME: 2.6.1.18

Entry

EC 2.6.1.18 Enzyme

Name

beta-alanine---pyruvate transaminase;
beta-alanine-pyruvate aminotransferase;
beta-alanine-alpha-alanine transaminase

Class

Transferases;
Transferring nitrogenous groups;
Transaminases

Sysname

L-alanine:3-oxopropanoate aminotransferase

Reaction(IUBMB)

L-alanine + 3-oxopropanoate = pyruvate + beta-alanine [RN:R00907]

Reaction(KEGG)

R00907;
(other) R04187

Substrate

L-alanine [CPD:C00041];
3-oxopropanoate [CPD:C00222]

Product

pyruvate [CPD:C00022];
beta-alanine [CPD:C00099]

Comment

A pyridoxal-phosphate protein.

Pathway

ec00280	Valine, leucine and isoleucine degradation
ec00410	beta-Alanine metabolism
ec00640	Propanoate metabolism
ec01100	Metabolic pathways

Orthology

K00822

beta-alanine--pyruvate transaminase

Genes

PWA:	Pecwa_3463
PEC:	W5S_3599
PLU:	plu2260
PAY:	PAU_02208
SPE:	Spro_0607
SRR:	SerAS9_0544
SRS:	SerAS12_0544
SRA:	SerAS13_0544
SMW:	SMWW4_v1c05550
XNE:	XNC1_2263
XCC:	XCC2357
XCB:	XC_1759
XCA:	xccb100_1815
XCV:	XCV2668
XCP:	XCR_2637
XAC:	XAC2489
XAX:	XACM_2468
XAO:	XAC29_12635
XOO:	XOO2793
XOM:	XOO_2635
XOP:	PXO_00471
XOR:	XOC_1989
XAL:	XALc_1971
XCI:	XCAW_02163(bioA)
SML:	Smlt1570(aptA)
SMT:	Smal_1329
BUJ:	BurJV3_1320
SMZ:	SMD_1401(aptA)
PSU:	Psesu_2112
PSD:	DSC_07475
VEJ:	VEJY3_23911
PAE:	PA0132 PA5313
PAU:	PA14_01620(aptA) PA14_70160(bioA)
PAP:	PSPA7_0208 PSPA7_6089
PAG:	PLES_01331 PLES_57081
PAF:	PAM18_0134 PAM18_5433
PNC:	NCGM2_0136(aptA) NCGM2_6078(bioA)
PDK:	PADK2_00675 PADK2_28300
PPU:	PP_0596
PPF:	Pput_0636
PPG:	PputGB1_0641
PPW:	PputW619_4567
PPT:	PPS_0595 PPS_2407
PPB:	PPUBIRD1_0646
PPI:	YSA_06218
PPX:	T1E_3767
PPUH:	B479_03495
PPUU:	PputUW4_00600
PST:	PSPTO_0774
PSB:	Psyr_0678
PSP:	PSPPH_4619
PFL:	PFL_0733
PFO:	Pfl01_0685
PFS:	PFLU0675
PFE:	PSF113_0704
PFC:	PflA506_0654
PPZ:	H045_24065
PEN:	PSEEN0681
PMY:	Pmen_3695
PMK:	MDS_4001
PSA:	PST_0045
PSZ:	PSTAB_0054
PSR:	PSTAA_0047
PSC:	A458_21215
PSJ:	PSJM300_18695
PSH:	Psest_4306
PBA:	PSEBR_a680
PFV:	Psefu_0759 Psefu_3751
PDR:	H681_00745
AVN:	Avin_22800
ACD:	AOLE_09080
ACB:	A1S_2233
ABY:	ABAYE1295
ABC:	ACICU_02439
ABN:	AB57_2594
ABB:	ABBFA_001206
ABX:	ABK1_1248
ABZ:	ABZJ_02567
ABR:	ABTJ_01283
ABD:	ABTW07_2631
ABH:	M3Q_2706
ABAD:	ABD1_22340
ACC:	BDGL_001265(aptA)
SON:	SO_3497(aptA)
SFR:	Sfri_3022
SAZ:	Sama_2649
SBL:	Sbal_1092
SBM:	Shew185_1152
SBN:	Sbal195_1186
SBP:	Sbal223_3203
SBT:	Sbal678_1214
SBS:	Sbal117_1195
SBB:	Sbal175_3179
SLO:	Shew_0966
SPC:	Sputcn32_1084
SHP:	Sput200_1085
SSE:	Ssed_1044
SPL:	Spea_0936
SHE:	Shewmr4_2927
SHM:	Shewmr7_3009
SHN:	Shewana3_3106
SHW:	Sputw3181_3080
SHL:	Shal_0986
SWD:	Swoo_1114
SWP:	swp_4178
CPS:	CPS_0099 CPS_4059
ALT:	ambt_18375
FBL:	Fbal_1148
HNA:	Hneap_2367
CSA:	Csal_1125
HEL:	HELO_1291
MMW:	Mmwyl1_1538
MME:	Marme_2927
MPC:	Mar181_2243
AHA:	AHA_0245
ASA:	ASA_4153
AVR:	B565_3829
OCE:	GU3_10110 GU3_12640
ACU:	Atc_m210
SAGA:	M5M_01995 M5M_03570
CVI:	CV_1436
PSE:	NH8B_0698
RSO:	RS02393(RSp1056)
RSL:	RPSI07_mp1089
RSN:	RSPO_m01363
RPI:	Rpic_4273
RPF:	Rpic12D_4383
REU:	Reut_A0248 Reut_C6274
REH:	H16_A0272(aptA)
RME:	Rmet_0205(aptA)
CTI:	RALTA_A0212
CNC:	CNE_1c02780
BMA:	BMA2175 BMAA1380
BMV:	BMASAVP1_0494 BMASAVP1_A0734(aptA)
BML:	BMA10229_0156 BMA10229_A2567(aptA)
BMN:	BMA10247_2046(aptA) BMA10247_A1454
BPS:	BPSL2650 BPSS0742
BPM:	BURPS1710b_3126(aptA) BURPS1710b_A2318
BPL:	BURPS1106A_3101(aptA) BURPS1106A_A1009
BPD:	BURPS668_3065(aptA) BURPS668_A1096
BPR:	GBP346_A3245
BPZ:	BP1026B_I0669 BP1026B_II0815
BPQ:	BPC006_I3144 BPC006_II1043
BTE:	BTH_I1505 BTH_II1658
BVI:	Bcep1808_4862
BUR:	Bcep18194_B1698
BCN:	Bcen_4053
BCH:	Bcen2424_4313
BCM:	Bcenmc03_3204
BCJ:	BCAM1441
BAM:	Bamb_3729
BAC:	BamMC406_4203
BMU:	Bmul_2481 Bmul_4294
BMJ:	BMULJ_00755(aptA) BMULJ_04212(aptA)
BCT:	GEM_4311
BXE:	Bxe_B0670
BPH:	Bphy_4468
BPY:	Bphyt_4248 Bphyt_4340
BGL:	bglu_2g13350
BUG:	BC1001_4276
BGE:	BC1002_4555
BGF:	BC1003_5131
BRH:	RBRH_02263
BGD:	bgla_2g13590
BYI:	BYI23_B008820
BUK:	MYA_4357
BPX:	BUPH_00860
BPE:	BP3157
BPC:	BPTD_3119
BPER:	BN118_2822
BPA:	BPP0784
BPAR:	BN117_0815
BBR:	BB0869
BBM:	BN115_0838
BBH:	BN112_2573
BPT:	Bpet4037
BAV:	BAV0504
AXY:	AXYL_01583 AXYL_05624
PUT:	PT7_2152
AKA:	TKWG_14370
RFR:	Rfer_0373
POL:	Bpro_4286
PNA:	Pnap_4039
AAV:	Aave_4744
AJS:	Ajs_4103
DIA:	Dtpsy_3455
AAA:	Acav_3442 Acav_4733
ACK:	C380_23635
VEI:	Veis_4437
DAC:	Daci_6020
DEL:	DelCs14_5897
VAP:	Vapar_1578 Vapar_4788
VPE:	Varpa_1742 Varpa_5449
CTT:	CtCNB1_4706
ADN:	Alide_4363
ADK:	Alide2_4693
RTA:	Rta_36600
MPT:	Mpe_A1898
HAR:	HEAR2429
MMS:	mma_2491
HSE:	Hsero_4647
CFU:	CFU_0091(aptA) CFU_3439
LCH:	Lcho_1742
TIN:	Tint_1874
THI:	THI_2310(aptA)
RGE:	RGE_25310 RGE_26220
AZO:	azo2100
AZA:	AZKH_0434 AZKH_2606
MEH:	M301_1030
BPRC:	D521_0670
PUB:	SAR11_0808(bioA)
PEL:	SAR11G3_00289
MLO:	mll1632
MCI:	Mesci_3099
MOP:	Mesop_3479
MAM:	Mesau_03365
MES:	Meso_2042
PLA:	Plav_0278
SME:	SMc01534 SMc04388
SMK:	Sinme_2452 Sinme_3285
SMQ:	SinmeB_2231 SinmeB_3060
SMX:	SM11_chr2554 SM11_chr3416
SMI:	BN406_02253 BN406_03089
SMEG:	C770_GR4Chr2507 C770_GR4Chr3385
SMEL:	SM2011_c01534 SM2011_c04388
SMD:	Smed_2317 Smed_3162
RHI:	NGR_b16510 NGR_c23690 NGR_c32980
SFH:	SFHH103_02240 SFHH103_03445
SFD:	USDA257_c47340 USDA257_c58070
ATU:	Atu3329(bioA)
ARA:	Arad_3278(bioA) Arad_8339
AVI:	Avi_3287(bioA)
AGR:	AGROH133_11225
RET:	RHE_CH03090 RHE_PF00434
REC:	RHECIAT_CH0003248 RHECIAT_PC0000657
RLE:	RL3538 pRL120419(aptA)
RLT:	Rleg2_2828 Rleg2_4833
RLG:	Rleg_3097 Rleg_4783
RTR:	RTCIAT899_CH13040
BME:	BMEII0371
BMI:	BMEA_B0909
BMZ:	BM28_B0893
BMG:	BM590_B0891
BMW:	BMNI_II0863
BMF:	BAB2_0309
BMB:	BruAb2_0307
BMC:	BAbS19_II02930
BAA:	BAA13334_II00716
BMS:	BRA0926
BSI:	BS1330_II0918
BMT:	BSUIS_B0918
BSV:	BSVBI22_B0917
BOV:	BOV_A0868
BCS:	BCAN_B0945
BSK:	BCA52141_II1708
BMR:	BMI_II920
BPP:	BPI_II982
OAN:	Oant_1442
BJA:	blr2221(bioA)
BJU:	BJ6T_76270
BRA:	BRADO2614 BRADO6061
BBT:	BBta_1722 BBta_7631
BRS:	S23_58000(bioA)
RPA:	RPA1179
RPB:	RPB_1184
RPC:	RPC_0894
RPD:	RPD_1288
RPE:	RPE_0915
RPT:	Rpal_1370
RPX:	Rpdx1_1349
NWI:	Nwi_2537
NHA:	Nham_3157
OCA:	OCAR_7226
OCG:	OCA5_c08870
OCO:	OCA4_c08860
AOL:	S58_62410
XAU:	Xaut_2299
AZC:	AZC_0729
SNO:	Snov_4452
MEX:	Mext_1294
MDI:	METDI1882(aptA)
MCH:	Mchl_1456
MRD:	Mrad2831_1078
MET:	M446_0765 M446_3237 M446_3868
MNO:	Mnod_3410 Mnod_4458
BID:	Bind_1242
HDN:	Hden_0971
HMC:	HYPMC_2758(aptA)
RVA:	Rvan_3098
PHL:	KKY_2264
CCR:	CC_3143
CCS:	CCNA_03245
CAK:	Caul_3957
CSE:	Cseg_0811
AEX:	Astex_1797
RCP:	RCAP_rcc02598
JAN:	Jann_2709 Jann_2848
DSH:	Dshi_1366
PSF:	PSE_0937 PSE_3264
OAT:	OAN307_c05480
OAR:	OA238_c01710
SAL:	Sala_1122
GOH:	B932_1613
ACR:	Acry_1964
AMV:	ACMV_22080
GDI:	GDI_2006
GDJ:	Gdia_0229
GXY:	GLX_03900
APT:	APA01_21580
APW:	APA42C_21580
APF:	APA03_21580
APU:	APA07_21580
APG:	APA12_21580
APQ:	APA22_21580
APX:	APA26_21580
APZ:	APA32_21580
RRU:	Rru_A1541
RRF:	F11_07950
RCE:	RC1_1469
RPM:	RSPPHO_00765
AZL:	AZL_a07230
ALI:	AZOLI_p10850
ABS:	AZOBR_p210064
TMO:	TMO_0945 TMO_a0345
THAL:	A1OE_295
APB:	SAR116_2023
PGV:	SL003B_2290
MAI:	MICA_441
MAN:	A11S_422
APC:	HIMB59_00001670
APM:	HIMB5_00003930
GAU:	GAU_3545
PBS:	Plabr_4276
CYA:	CYA_0689
CYB:	CYB_2128
SYNE:	Syn6312_2677
TEL:	tlr0408
CYN:	Cyan7425_3898
GLP:	Glo7428_0159
ONI:	Osc7112_4921
MIC:	Mic7113_4971
CTHE:	Chro_2778

» show all

Reference

1 [PMID:13712439]

Authors

HAYAISHI O, NISHIZUKA Y, TATIBANA M, TAKESHITA M, KUNO S.

Title

Enzymatic studies on the metabolism of beta-alanine.

Journal

J. Biol. Chem. 236 (1961) 781-90.

Organism

Pseudomonas fluorescens

Reference

2 [PMID:5762452]

Authors

Stinson RA, Spencer MS.

Title

Beta alanine aminotransferase (s) from a plant source.

Journal

Biochem. Biophys. Res. Commun. 34 (1969) 120-7.

Organism

Phaseolus vulgaris

Other DBs

ExplorEnz - The Enzyme Database:

2.6.1.18

IUBMB Enzyme Nomenclature:

2.6.1.18

ExPASy - ENZYME nomenclature database:

2.6.1.18

BRENDA, the Enzyme Database:

2.6.1.18

CAS:

61461-61-8

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (12)   
   KEGG REACTION (2)   
   KEGG RPAIR (7)   
   KEGG RCLASS (3)   
Gene (441)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (402)   
   KEGG DGENES (1)   
   KEGG EGENES (15)   
   KEGG MGENES (22)   
Protein sequence (1005)   
   UniProt (426)   
   PRF (29)   
   RefSeq(pep) (517)   
   PDBSTR (33)   
DNA sequence (903)   
   RefSeq(nuc) (496)   
   GenBank (201)   
   EMBL (206)   
3D Structure (10)   
   PDB (10)   
Protein domain (1)   
   PROSITE(DOC) (1)   
Literature (2)   
   PubMed (2)   
Enzyme (4)   
   BRENDA (1)   
   EXPASY-ENZYME (1)   
   EXPLORENZ (1)   
   IUBMB (1)   
All databases (2398)   

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