KEGG   ENZYME: 2.6.1.33Help
Entry
EC 2.6.1.33                 Enzyme                                 

Name
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase;
thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase;
thymidine diphospho-4-amino-6-deoxyglucose aminotransferase;
thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase;
thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase;
TDP-4-keto-6-deoxy-D-glucose transaminase;
VioA;
dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
BRITE hierarchy
Sysname
dTDP-4-amino-4,6-dideoxy-alpha-D-glucose:2-oxoglutarate aminotransferase
Reaction(IUBMB)
dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate [RN:R02773]
Reaction(KEGG)
R02773;
(other) R02772
Show
Substrate
dTDP-4-amino-4,6-dideoxy-alpha-D-glucose [CPD:C04268];
2-oxoglutarate [CPD:C00026]
Product
dTDP-4-dehydro-6-deoxy-alpha-D-glucose [CPD:C11907];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.33 created 1972
Pathway
Polyketide sugar unit biosynthesis
Orthology
K13308  
dTDP-4-amino-4,6- dideoxyglucose
Reference
1  [PMID:5332731]
  Authors
Matsuhashi M, Strominger JL.
  Title
Thymidine diphosphate 4-acetamido-2,6-dideoxyhexoses. 3. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Escherichia coli strain B.
  Journal
J. Biol. Chem. 241 (1966) 4738-44.
Reference
2  [PMID:17905981]
  Authors
Wang Y, Xu Y, Perepelov AV, Qi Y, Knirel YA, Wang L, Feng L
  Title
Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7.
  Journal
J. Bacteriol. 189 (2007) 8626-35.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9023-19-2

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