KEGG   ENZYME: 2.7.1.150Help
Entry
EC 2.7.1.150                Enzyme                                 

Name
1-phosphatidylinositol-3-phosphate 5-kinase;
type III PIP kinase;
phosphatidylinositol 3-phosphate 5-kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase
Reaction(IUBMB)
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [RN:R05802]
Reaction(KEGG)
R05802;
(other) R10951
Show
Substrate
ATP [CPD:C00002];
1-phosphatidyl-1D-myo-inositol 3-phosphate [CPD:C04549]
Product
ADP [CPD:C00008];
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [CPD:C11556]
History
EC 2.7.1.150 created 2002
Pathway
ec00562  Inositol phosphate metabolism
Orthology
K00921  1-phosphatidylinositol-3-phosphate 5-kinase
Genes
HSA: 200576(PIKFYVE)
PTR: 459908(PIKFYVE)
PPS: 100981447(PIKFYVE)
GGO: 101152226(PIKFYVE)
PON: 100435223(PIKFYVE)
NLE: 100592353(PIKFYVE)
MCC: 710115(PIKFYVE)
MCF: 102116640(PIKFYVE)
CSAB: 103217737(PIKFYVE)
RRO: 104672971(PIKFYVE)
RBB: 108540354(PIKFYVE)
CJC: 100415724(PIKFYVE)
SBQ: 101028683(PIKFYVE)
MMU: 18711(Pikfyve)
RNO: 316457(Pikfyve)
CGE: 100758487(Pikfyve)
NGI: 103744454(Pikfyve)
HGL: 101705294(Pikfyve)
OCU: 100357384(PIKFYVE)
TUP: 102469769(PIKFYVE)
CFA: 478890(PIKFYVE)
AML: 100480413(PIKFYVE)
UMR: 103659810(PIKFYVE)
ORO: 101377889(PIKFYVE)
FCA: 101094121(PIKFYVE)
PTG: 102966673(PIKFYVE)
AJU: 106967092(PIKFYVE)
BTA: 790873(PIKFYVE)
BOM: 102287865(PIKFYVE)
BIU: 109570228 109570267(PIKFYVE)
PHD: 102321423(PIKFYVE)
CHX: 102190275(PIKFYVE)
OAS: 101120727(PIKFYVE)
SSC: 100521692(PIKFYVE)
CFR: 102506136(PIKFYVE)
CDK: 105093550(PIKFYVE)
BACU: 103019601(PIKFYVE)
LVE: 103085543(PIKFYVE)
OOR: 101283366(PIKFYVE)
ECB: 100066445(PIKFYVE)
EPZ: 103540345(PIKFYVE)
EAI: 106828171(PIKFYVE)
MYB: 102241986(PIKFYVE)
MYD: 102758354(PIKFYVE)
HAI: 109388303(PIKFYVE)
RSS: 109445042(PIKFYVE)
PALE: 102891645(PIKFYVE)
LAV: 100672120(PIKFYVE)
TMU: 101359894
MDO: 100013564(PIKFYVE)
SHR: 100933218(PIKFYVE)
OAA: 100076756(PIKFYVE)
GGA: 424114(PIKFYVE)
MGP: 100544400(PIKFYVE)
CJO: 107316589(PIKFYVE)
APLA: 101800759(PIKFYVE)
ACYG: 106030055(PIKFYVE)
TGU: 100229363(PIKFYVE)
GFR: 102039163(PIKFYVE)
FAB: 101821332(PIKFYVE)
PHI: 102112726(PIKFYVE)
PMAJ: 107207464(PIKFYVE)
CCW: 104693820(PIKFYVE)
FPG: 101923292(PIKFYVE)
FCH: 102057143(PIKFYVE)
CLV: 102089113(PIKFYVE)
EGZ: 104125088(PIKFYVE)
AAM: 106492453(PIKFYVE)
ASN: 102388365(PIKFYVE)
AMJ: 102568408(PIKFYVE)
PSS: 102459996(PIKFYVE)
CMY: 102942791(PIKFYVE)
CPIC: 101941143(PIKFYVE)
ACS: 100566486(pikfyve)
PVT: 110072395(PIKFYVE)
PBI: 103055422(PIKFYVE)
GJA: 107105889(PIKFYVE)
XLA: 108701477
XTR: 550069(pikfyve)
NPR: 108790184(PIKFYVE) 108802352
DRE: 337690(pikfyve)
SANH: 107681306 107682958 107690613(pikfyve)
IPU: 108266285(pikfyve)
AMEX: 103023917(pikfyve)
TRU: 101078741(pikfyve)
LCO: 104932524(pikfyve)
NCC: 104958889
MZE: 101469447(pikfyve)
OLA: 101160530(pikfyve)
XMA: 102220346(pikfyve)
PRET: 103482175(pikfyve)
NFU: 107389520(pikfyve)
CSEM: 103391640(pikfyve)
LCF: 108902449(pikfyve)
HCQ: 109520001(pikfyve)
BPEC: 110170588(pikfyve)
SASA: 100380630(fyv1) 106586374
ELS: 105016282(pikfyve)
SFM: 108926494(pikfyve)
LCM: 102366969(PIKFYVE)
CMK: 103182931(pikfyve)
CIN: 723796(ci-zf(fyve)-8)
APLC: 110983433
SKO: 102809692
DME: Dmel_CG6355(fab1)
DSI: Dsimw501_GD25438(Dsim_GD25438)
MDE: 101888475
AAG: 5574640
AME: 410183(fab1)
BIM: 100741836
BTER: 100643432
SOC: 105201430
AEC: 105152151
ACEP: 105621988
PBAR: 105429104
HST: 105192060
CFO: 105249010
LHU: 105679812
PGC: 109856183
NVI: 100122133
TCA: 658852
DPA: 109539339
NVL: 108562777
PMAC: 106716087
PRAP: 110992518
API: 100161846
DNX: 107161632
ZNE: 110829128
FCD: 110843460
TUT: 107363789
BMY: Bm1_33365
TSP: Tsp_05920
CRG: 105338263
MYI: 110449617
OBI: 106882632
SHX: MS3_08890
HMG: 101240098
AQU: 100642005
ATH: AT1G34260(FAB1D) AT1G71010(FAB1C) AT3G14270(FAB1B) AT4G33240(FAB1A)
LJA: Lj3g3v2575590.1(Lj3g3v2575590.1) Lj4g3v2215310.1(Lj4g3v2215310.1) Lj6g3v0072130.1(Lj6g3v0072130.1) Lj6g3v0072140.1(Lj6g3v0072140.1) Lj6g3v0072140.2(Lj6g3v0072140.2)
DOSA: Os03t0399532-00(Os03g0399532) Os04t0691900-01(Os04g0691900) Os06t0259000-01(Os06g0259000) Os08t0104700-01(Os08g0104700) Os08t0428900-01(Os08g0428900) Os08t0450700-01(Os08g0450700) Os08t0450800-01(Os08g0450800) Os09t0278300-00(Os09g0278300) Os09t0402300-01(Os09g0402300) Os12t0236700-01(Os12g0236700)
ATS: 109732723(LOC109732723) 109736337(LOC109736337) 109741036(LOC109741036) 109743211(LOC109743211) 109744854(LOC109744854) 109750550(LOC109750550) 109759052(LOC109759052) 109772042(LOC109772042)
APRO: F751_4351
SCE: YFR019W(FAB1)
KMX: KLMA_20473(FAB1)
NCS: NCAS_0D00550(NCAS0D00550)
NDI: NDAI_0H03600(NDAI0H03600)
TPF: TPHA_0A02260(TPHA0A02260)
TBL: TBLA_0A10150(TBLA0A10150)
TDL: TDEL_0D02300(TDEL0D02300)
KAF: KAFR_0C04440(KAFR0C04440)
PIC: PICST_59054(FAB1)
CAL: CAALFM_C201990CA(FAB1)
CDU: CD36_16790(FAB1)
CAUR: QG37_00471
SLB: AWJ20_3164(FAB1)
NCR: NCU02083
NTE: NEUTE1DRAFT89270(NEUTE1DRAFT_89270)
SMP: SMAC_04978(putative fab1)
MGR: MGG_14757
MAW: MAC_05526
MAJ: MAA_05182
CMT: CCM_07600
MBE: MBM_09238
ANG: ANI_1_1124064(An07g08980)
CIM: CIMG_13275(CIMG08037)
ABE: ARB_06188
TVE: TRV_01658
PTE: PTT_11698
SPO: SPBC3E7.01(fab1)
CNE: CND03330
CNB: CNBD3020
ABP: AGABI1DRAFT124322(AGABI1DRAFT_124322) AGABI1DRAFT80588(AGABI1DRAFT_80588)
ABV: AGABI2DRAFT113973(AGABI2DRAFT_113973) AGABI2DRAFT122330(AGABI2DRAFT_122330)
MGL: MGL_0467
DDI: DDB_G0279149(pip5k3)
DFA: DFA_10824(pip5k3)
SMIN: v1.2.039655.t1(symbB.v1.2.039655.t1)
EHX: EMIHUDRAFT_449069(FAB1)
GTT: GUITHDRAFT_143864(FAB1)
 » show all
Taxonomy
Reference
1  [PMID:9811604]
  Authors
Cooke FT, Dove SK, McEwen RK, Painter G, Holmes AB, Hall MN, Michell RH, Parker PJ.
  Title
The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae.
  Journal
Curr. Biol. 8 (1998) 1219-22.
  Sequence
[sce:YFR019W]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.150
IUBMB Enzyme Nomenclature: 2.7.1.150
ExPASy - ENZYME nomenclature database: 2.7.1.150
BRENDA, the Enzyme Database: 2.7.1.150

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