KEGG   ENZYME: 2.7.1.52Help
Entry
EC 2.7.1.52                 Enzyme                                 
Name
fucokinase;
fucokinase (phosphorylating);
fucose kinase;
L-fucose kinase;
L-fucokinase;
ATP:6-deoxy-L-galactose 1-phosphotransferase;
ATP:L-fucose 1-phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:beta-L-fucose 1-phosphotransferase
Reaction(IUBMB)
ATP + L-fucose = ADP + beta-L-fucose 1-phosphate [RN:R03161]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
L-fucose [CPD:C01019]
Product
ADP [CPD:C00008];
beta-L-fucose 1-phosphate [CPD:C02985]
Comment
Requires a divalent cation for activity, with Mg2+ and Fe2+ giving rise to the highest enzyme activity. Forms part of a salvage pathway for reutilization of L-fucose. Can also phosphorylate D-arabinose, but more slowly.
Pathway
Fructose and mannose metabolism
Amino sugar and nucleotide sugar metabolism
Metabolic pathways
Orthology
K05305  
fucokinase
Genes
HSA: 
197258(FUK)
PTR: 
468015(FUK)
PPS: 
GGO: 
PON: 
MCC: 
709226(FUK)
MMU: 
234730(Fuk)
RNO: 
307848(Fuk)
CFA: 
489715(FUK)
AML: 
FCA: 
101094896(FUK)
BTA: 
519181(FUK)
SSC: 
100625448(FUK)
ECB: 
100054844(FUK)
SHR: 
100917218 100931802
OAA: 
100075033
GGA: 
770049(FUK)
TGU: 
100228545(FUK)
ACS: 
100558701
XLA: 
100137687(fuk)
XTR: 
100497304(fuk)
DRE: 
100150934
TRU: 
101074270
OLA: 
101172159
BFO: 
BRAFLDRAFT_92868
CIN: 
100182438
SPU: 
100892878(fuk)
NVE: 
NEMVE_v1g168454
TAD: 
TRIADDRAFT_55543 TRIADDRAFT_55544
ATH: 
AT1G01220(FKGP)
ALY: 
ARALYDRAFT_470155
GMX: 
100776147 100803620
MTR: 
MTR_7g117870
CSV: 
101204338
RCU: 
RCOM_0716030
POP: 
POPTR_664148
VVI: 
100258719
OSA: 
4331392
DOSA: 
Os03t0115100-01(Os03g0115100)
BDI: 
100826076
SBI: 
SORBI_01g049620(SORBIDRAFT_01g049620)
ZMA: 
100381824
PPP: 
PHYPADRAFT_171137
OTA: 
Ot07g01120
MBR: 
MONBRDRAFT_15021
DDI: 
DDB_G0269678
DPP: 
DICPUDRAFT_49164
TCR: 
508379.10
LMA: 
LMJF_16_0440 LMJF_16_0480
LIF: 
LINJ_16_0450 LINJ_16_0490
LDO: 
LDBPK_160450
LMI: 
LMXM_16_0480
LBZ: 
LBRM_16_0500
PTI: 
PHATRDRAFT_bd1431
TPS: 
THAPSDRAFT_11189
SGY: 
Sgly_1597
ROB: 
CK5_28240
RTO: 
RTO_22660
SUS: 
Acid_0569(fkp)
 » show all
Taxonomy
Reference
1  [PMID:5646161]
  Authors
Ishihara H, Massaro DJ, Heath EC.
  Title
The metabolism of L-fucose. 3. The enzymatic synthesis of beta-L-fucose 1-phosphate.
  Journal
J. Biol. Chem. 243 (1968) 1103-9.
  Organism
Sus scofa [GN:ssc]
Reference
2  [PMID:2986701]
  Authors
Butler W, Serif GS.
  Title
Fucokinase, its anomeric specificity and mechanism of phosphate group transfer.
  Journal
Biochim. Biophys. Acta. 829 (1985) 238-43.
Reference
3  [PMID:9488699]
  Authors
Park SH, Pastuszak I, Drake R, Elbein AD.
  Title
Purification to apparent homogeneity and properties of pig kidney L-fucose kinase.
  Journal
J. Biol. Chem. 273 (1998) 5685-91.
  Organism
Sus scofa [GN:ssc]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37278-00-5
DBGET integrated database retrieval system