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Entry
EC 2.7.11.25                Enzyme                                 

Name
mitogen-activated protein kinase kinase kinase;
cMos;
cRaf;
MAPKKK;
MAP3K;
MAP kinase kinase kinase;
MEKK;
MEKK1;
MEKK2;
MEKK3;
MEK kinase;
Mil/Raf;
MLK-like mitogen-activated protein triple kinase;
MLTK;
MLTKa;
MLTKb;
REKS;
STK28
Class
Transferases;
Transferring phosphorus-containing groups;
Protein-serine/threonine kinases
BRITE hierarchy
Sysname
ATP:protein phosphotransferase (MAPKKKK-activated)
Reaction(IUBMB)
ATP + a protein = ADP + a phosphoprotein [RN:R00162]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
protein [CPD:C00017]
Product
ADP [CPD:C00008];
phosphoprotein [CPD:C00562]
Comment
This enzyme phosphorylates and activates its downstream protein kinase, EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) but requires MAPKKKK for activation. Some members of this family can be activated by p21-activated kinases (PAK/STE20) or Ras. While c-Raf and c-Mos activate the classical MAPK/ERK pathway, MEKK1 and MEKK2 preferentially activate the c-Jun N-terminal protein kinase(JNK)/stress-activated protein kinase (SAPK) pathway [2]. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth factor and platelet-derived growth factor), vasoactive peptides (e.g. angiotensin-II and endothelin), inflammatory cytokines of the tumour necrosis factor (TNF) family and environmental stresses such as osmotic shock, ionizing radiation and ischaemic injury.
History
EC 2.7.11.25 created 2005 (EC 2.7.1.37 part-incorporated 2005)
Orthology
K04415  
mitogen-activated protein kinase kinase kinase 8
K04416  
mitogen-activated protein kinase kinase kinase 1
K04417  
mitogen-activated protein kinase kinase kinase 9
K04418  
mitogen-activated protein kinase kinase kinase 10
K04419  
mitogen-activated protein kinase kinase kinase 11
K04420  
mitogen-activated protein kinase kinase kinase 2
K04421  
mitogen-activated protein kinase kinase kinase 3
K04422  
mitogen-activated protein kinase kinase kinase 13
K04423  
mitogen-activated protein kinase kinase kinase 12
K04424  
sterile alpha motif and leucine zipper containing kinase AZK
K04425  
mitogen-activated protein kinase kinase kinase 6
K04426  
mitogen-activated protein kinase kinase kinase 5
K04427  
mitogen-activated protein kinase kinase kinase 7
K04428  
mitogen-activated protein kinase kinase kinase 4
K04466  
mitogen-activated protein kinase kinase kinase 14
K11228  
mitogen-activated protein kinase kinase kinase
K11229  
mitogen-activated protein kinase kinase kinase
K11230  
mitogen-activated protein kinase kinase kinase
K13414  
mitogen-activated protein kinase kinase kinase 1
K13986  
mitogen-activated protein kinase kinase kinase 15
K17533  
mitogen-activated protein kinase kinase kinase 19
K17534  
mitogen-activated protein kinase kinase kinase MLK4
K20605  
mitogen-activated protein kinase kinase kinase 2
K20606  
mitogen-activated protein kinase kinase kinase ANP1
K20717  
mitogen-activated protein kinase kinase kinase YODA
Genes
HSA: 
10746(MAP3K2) 1326(MAP3K8) 389840(MAP3K15) 4214(MAP3K1) 4215(MAP3K3) 4216(MAP3K4) 4217(MAP3K5) 4293(MAP3K9) 4294(MAP3K10) 4296(MAP3K11) 51776(MAP3K20) 6885(MAP3K7) 7786(MAP3K12) 80122(MAP3K19) 84451(MAP3K21) 9020(MAP3K14) 9064(MAP3K6) 9175(MAP3K13)
PTR: 
450384(MAP3K8) 451326(MAP3K11) 451940(MAP3K12) 454750(MAP3K14) 456674(MAP3K6) 459745(MAP3K20) 462888(MAP3K7) 463023(MAP3K5) 463119(MAP3K4) 465526(MAP3K15) 467498(MAP3K9) 468286(MAP3K3) 468880(MAP3K10) 469711(MAP3K21) 470547(MAP3K19) 471543(MAP3K1) 736244(MAP3K2) 737524(MAP3K13)
PPS: 
100969705(MAP3K3) 100971946(MAP3K21) 100973371(MAP3K2) 100974026(MAP3K7) 100975785(MAP3K15) 100977883(MAP3K10) 100978161(MAP3K8) 100981441(MAP3K4) 100983287(MAP3K12) 100984930(MAP3K14) 100985472(MAP3K13) 100985853(MAP3K11) 100990426(MAP3K9) 100991014(MAP3K5) 100992106(MAP3K19) 100992712(MAP3K6) 100994192(MAP3K20) 100994796(MAP3K1)
GGO: 
101128207(MAP3K13) 101129821(MAP3K15) 101130070(MAP3K21) 101132363(MAP3K19) 101133328(MAP3K8) 101135149(MAP3K9) 101136722(MAP3K1) 101137766(MAP3K6) 101144707(MAP3K7) 101147354(MAP3K5) 101147819(MAP3K14) 101148044(MAP3K3) 101148067(MAP3K10) 101148964(MAP3K11) 101149805(MAP3K2) 101151387(MAP3K12) 101152649(MAP3K4) 101154523(MAP3K20) 109025231
PON: 
100171454(MAP3K7) 100172208(MAP3K12) 100172983(MAP3K13) 100433831(MAP3K9) 100434157(MAP3K8) 100436201(MAP3K14) 100440278(MAP3K20) 100442172(MAP3K4) 100444678(MAP3K3) 100445147(MAP3K6) 100448142(MAP3K19) 100450054(MAP3K2) 100450400(MAP3K21) 100450681(MAP3K10) 100452447(MAP3K15) 100453309(MAP3K1) 100456749(MAP3K11) 100458776(MAP3K5)
NLE: 
100579516(MAP3K8) 100583302(MAP3K6) 100587332(MAP3K5) 100587341(MAP3K13) 100588106(MAP3K11) 100588522(MAP3K10) 100589608(MAP3K9) 100590602(MAP3K15) 100595740(MAP3K21) 100596471(MAP3K7) 100596886(MAP3K12) 100599140(MAP3K19) 100600394(MAP3K14) 100601763(MAP3K3) 100601802(MAP3K2) 100602313(MAP3K4) 100603568(MAP3K20) 100606554(MAP3K1)
MCC: 
100424131(MAP3K2) 693835(MAP3K9) 695958(MAP3K15) 696936(MAP3K8) 698274(MAP3K20) 700477(MAP3K10) 701085(MAP3K13) 703059(MAP3K12) 703101(MAP3K7) 710360(MAP3K4) 710979(MAP3K1) 711382(MAP3K5) 712728(MAP3K19) 712755(MAP3K21) 715911(MAP3K6) 716038(MAP3K11) 716258(MAP3K14) 717866(MAP3K3)
MCF: 
101865276(MAP3K4) 101925622(MAP3K12) 101925657(MAP3K5) 101926191(MAP3K11) 102116023 102119428(MAP3K13) 102123041(MAP3K1) 102123979(MAP3K9) 102124252(MAP3K6) 102124587(MAP3K15) 102129200(MAP3K19) 102129741(MAP3K21) 102132095(MAP3K3) 102132262(MAP3K10) 102132599(MAP3K8) 102138136(MAP3K2) 102139881(MAP3K20) 102140498(MAP3K7) 102145584(MAP3K14)
CSAB: 
103216879(MAP3K2) 103216980(MAP3K19) 103217331(MAP3K20) 103221113(MAP3K13) 103221701(MAP3K1) 103225290(MAP3K6) 103227627(MAP3K11) 103229274(MAP3K9) 103230770(MAP3K21) 103231683(MAP3K15) 103234697(MAP3K10) 103238400(MAP3K12) 103240115(MAP3K7) 103240310(MAP3K5) 103240840(MAP3K4) 103243225(MAP3K3) 103243289(MAP3K14) 103247459(MAP3K8)
RRO: 
104657086(MAP3K1) 104657273(MAP3K8) 104657888(MAP3K7) 104660313(MAP3K9) 104662431(MAP3K2) 104664818(MAP3K11) 104665553(MAP3K19) 104669999(MAP3K4) 104670592(MAP3K12) 104672741(MAP3K13) 104673509(MAP3K20) 104675014(MAP3K5) 104675466(MAP3K3) 104675763(MAP3K6) 104676124(MAP3K10) 104678324(MAP3K21) 104678377(MAP3K14) 104682410(MAP3K15)
CJC: 
100385107(MAP3K8) 100385131(MAP3K9) 100387775(MAP3K11) 100389500(MAP3K1) 100393421(MAP3K19) 100395753(MAP3K13) 100395802(MAP3K10) 100396743(MAP3K21) 100401112(MAP3K14) 100401384(MAP3K20) 100403175(MAP3K7) 100404784(MAP3K6) 100406322(MAP3K5) 100406711(MAP3K2) 100408788(MAP3K12) 100409244(MAP3K15) 100409608(MAP3K3) 100413660(MAP3K4)
SBQ: 
101031938(MAP3K12) 101034123(MAP3K5) 101034729(MAP3K19) 101035755(MAP3K3) 101035799(MAP3K2) 101038273(MAP3K6) 101038631(MAP3K10) 101039966(MAP3K11) 101042401(MAP3K4) 101043045 101043439 101044826(MAP3K14) 101045636(MAP3K7) 101046566(MAP3K8) 101049991(MAP3K13) 101050832(MAP3K15) 101051154(MAP3K9) 101052309 101054366(MAP3K1)
MMU: 
22625(Map3k19) 234878(Map3k21) 26401(Map3k1) 26403(Map3k11) 26404(Map3k12) 26405(Map3k2) 26406(Map3k3) 26407(Map3k4) 26408(Map3k5) 26409(Map3k7) 26410(Map3k8) 269881(Map3k10) 270672(Map3k15) 338372(Map3k9) 53608(Map3k6) 53859(Map3k14) 65964(Map3k20) 71751(Map3k13)
RNO: 
100910771 100912399 116596(Map3k8) 116667(Map3k1) 171492(Map3k2) 25579(Map3k12) 289001(Map3k19) 303604(Map3k3) 303823(Map3k13) 307950(Map3k21) 308106(Map3k4) 308463(Map3k10) 309168(Map3k11) 311743(Map3k20) 313022(Map3k6) 313121(Map3k7) 360640(Map3k14) 365057(Map3k5) 500690(Map3k9) 501558(Map3k15)
CGE: 
100751831(Map3k15) 100752376(Map3k5) 100753508(Map3k3) 100754991(Map3k13) 100759538(Map3k8) 100760135(Map3k6) 100762677(Map3k11) 100762934(Map3k9) 100764060(Map3k4) 100764739(Map3k19) 100765738(Map3k12) 100766459(Map3k14) 100768062(Map3k10) 100769818(Map3k20) 100770540(Map3k1) 100771548(Map3k21) 100772559(Map3k2) 100774341(Map3k7) 107977146
NGI: 
103724902(Map3k5) 103724991(Map3k11) 103725874(Map3k9) 103732132(Map3k2) 103732670(Map3k13) 103733589(Map3k19) 103736239(Map3k15) 103737023(Map3k4) 103737078(Map3k6) 103738320(Map3k14) 103738660(Map3k12) 103739547(Map3k7) 103739909(Map3k1) 103743128(Map3k21) 103744757(Map3k3) 103747991(Map3k8) 103750755(Map3k10) 103751744(Map3k20)
HGL: 
101696673(Map3k9) 101697616(Map3k6) 101700680(Map3k13) 101701961(Map3k4) 101702332(Map3k12) 101702514(Map3k15) 101703313(Map3k14) 101704125(Map3k21) 101704335(Map3k3) 101707762(Map3k20) 101710286(Map3k8) 101712051(Map3k5) 101718269(Map3k7) 101718471(Map3k10) 101718575(Map3k11) 101720769(Map3k1) 101725578(Map3k19) 101726195(Map3k2)
OCU: 
100340498(MAP3K5) 100341731(MAP3K9) 100343069(MAP3K6) 100343571(MAP3K7) 100343621(MAP3K10) 100345602(MAP3K13) 100345607(MAP3K21) 100348484(MAP3K1) 100350329(MAP3K19) 100351032(MAP3K14) 100351826(MAP3K20) 100355324(MAP3K3) 100355566(MAP3K8) 100355693(MAP3K2) 100356691(MAP3K11) 100357608(MAP3K15) 100358104(MAP3K4) 100358158(MAP3K12)
TUP: 
102470721(MAP3K9) 102471323(MAP3K10) 102474694(MAP3K12) 102477331(MAP3K7) 102477673(MAP3K3) 102478254(MAP3K13) 102479529(MAP3K21) 102479582(MAP3K4) 102483890(MAP3K1) 102485186(MAP3K2) 102490022(MAP3K11) 102493021(MAP3K8) 102495244(MAP3K5) 102500729(MAP3K14) 102500878(MAP3K19) 102501118(MAP3K20) 102503019(MAP3K15) 102503262(MAP3K6)
CFA: 
100685499(MAP3K13) 100688368(MAP3K21) 102156745(MAP3K7) 476215(MAP3K5) 476262(MAP3K4) 478061(MAP3K1) 478802(MAP3K20) 480481(MAP3K3) 483732(MAP3K11) 483897(MAP3K19) 484504(MAP3K10) 487085(MAP3K8) 487345(MAP3K6) 490765(MAP3K9) 490926(MAP3K14) 491765(MAP3K15) 607170(MAP3K12) 612902(MAP3K2)
AML: 
100465667(MAP3K4) 100466442(MAP3K1) 100466506(MAP3K7) 100467807(MAP3K13) 100469942(MAP3K12) 100472044(MAP3K9) 100472260(MAP3K14) 100473197(MAP3K10) 100475304(MAP3K5) 100475390(MAP3K21) 100475426(MAP3K2) 100475740(MAP3K3) 100479214(MAP3K6) 100479844(MAP3K20) 100480593(MAP3K8) 100480913(MAP3K11) 100483854(MAP3K19) 105241834(MAP3K15)
UMR: 
103656496(MAP3K8) 103658571(MAP3K2) 103659570(MAP3K20) 103659895 103660092(MAP3K7) 103660898(MAP3K4) 103661092(MAP3K10) 103661981(MAP3K21) 103663496(MAP3K5) 103663891(MAP3K1) 103665628(MAP3K3) 103665883(MAP3K14) 103666761(MAP3K6) 103667667(MAP3K19) 103668259(MAP3K15) 103671518(MAP3K9) 103675534(MAP3K12) 103676070(MAP3K13) 103679581(MAP3K11)
FCA: 
101081315(MAP3K6) 101082912(MAP3K5) 101083468(MAP3K14) 101083633(MAP3K3) 101084717(MAP3K9) 101087164(MAP3K12) 101087784(MAP3K21) 101089731(MAP3K10) 101089836(MAP3K15) 101090328(MAP3K1) 101090454(MAP3K19) 101090624(MAP3K8) 101093205(MAP3K13) 101094038(MAP3K20) 101095899(MAP3K7) 101096406(MAP3K2) 101097977(MAP3K4) 101098654(MAP3K11)
PTG: 
102948678(MAP3K9) 102952700(MAP3K4) 102957300(MAP3K12) 102957925(MAP3K2) 102959520(MAP3K20) 102960317(MAP3K5) 102960849(MAP3K15) 102961042(MAP3K8) 102961509(MAP3K10) 102963341(MAP3K7) 102963818(MAP3K6) 102964388(MAP3K14) 102965107(MAP3K13) 102966576(MAP3K3) 102969655(MAP3K19) 102970826(MAP3K21) 102971191(MAP3K1)
AJU: 
106966378(MAP3K2) 106967988(MAP3K13) 106971139(MAP3K11) 106974370(MAP3K9) 106975243(MAP3K1) 106975683(MAP3K19) 106977317(MAP3K8) 106977571(MAP3K6) 106978686(MAP3K3) 106979597(MAP3K10) 106981653(MAP3K21) 106981924(MAP3K15) 106983077(MAP3K7) 106983084(MAP3K12) 106983673(MAP3K5) 106985032(MAP3K4) 106987964(MAP3K20) 106988147(MAP3K14)
BTA: 
504592(MAP3K2) 505369(MAP3K13) 505427(MAP3K12) 508367(MAP3K14) 508943(MAP3K3) 511779(MAP3K4) 514210(MAP3K11) 519251(MAP3K20) 523962(MAP3K1) 529146(MAP3K7) 529335(MAP3K15) 535622(MAP3K8) 537380(MAP3K5) 538340(MAP3K9) 538897(MAP3K19) 614598(MAP3K6) 616014(MAP3K21) 781037(MAP3K10)
BOM: 
102264669(MAP3K6) 102264816(MAP3K7) 102267592(MAP3K1) 102268339(MAP3K14) 102271481(MAP3K9) 102273125(MAP3K2) 102274075(MAP3K21) 102274152(MAP3K10) 102275307(MAP3K3) 102276849(MAP3K5) 102276927(MAP3K19) 102278856(MAP3K8) 102279268(MAP3K11) 102281279(MAP3K12) 102282362(MAP3K15) 102283969(MAP3K4) 102285655(MAP3K13) 102288137(MAP3K20)
PHD: 
102316264(MAP3K7) 102319571(MAP3K5) 102321628(MAP3K12) 102323190(MAP3K11) 102324731(MAP3K10) 102324733(MAP3K21) 102326524(MAP3K14) 102328534(MAP3K4) 102329106(MAP3K1) 102329226(MAP3K6) 102329999(MAP3K8) 102332756(MAP3K2) 102332784(MAP3K3) 102333533(MAP3K9) 102334682(MAP3K19) 102338925(MAP3K15) 102341085(MAP3K20) 102341362(MAP3K13)
CHX: 
102168436(MAP3K15) 102172156(MAP3K5) 102172543(MAP3K4) 102172719(MAP3K7) 102172769(MAP3K19) 102173036(MAP3K3) 102173267(MAP3K11) 102174723(MAP3K12) 102175623(MAP3K2) 102178859(MAP3K13) 102180599(MAP3K9) 102183919(MAP3K20) 102186147(MAP3K10) 102186443(MAP3K6) 102187530(MAP3K1) 102188512(MAP3K8) 102189617(MAP3K14) 102191110(MAP3K21) 108634540
OAS: 
101102889(MAP3K12) 101103160(MAP3K9) 101104888(MAP3K15) 101106493(MAP3K19) 101108056(MAP3K7) 101108969(MAP3K11) 101109858(MAP3K2) 101111776(MAP3K20) 101112260(MAP3K1) 101113246(MAP3K4) 101113737(MAP3K6) 101115427(MAP3K21) 101117036(MAP3K13) 101117094(MAP3K8) 101118723(MAP3K10) 101118799(MAP3K14) 101121018(MAP3K5) 101122537(MAP3K3)
SSC: 
100135663(MAP3K7) 100152572(MAP3K20) 100154002(MAP3K21) 100154202 100155753(MAP3K9) 100511286(MAP3K19) 100512235(MAP3K6) 100513491(MAP3K3) 100515448(MAP3K13) 100517714(MAP3K12) 100518455(MAP3K4) 100520402(MAP3K14) 100521453(MAP3K10) 100621234(MAP3K2) 100622217(MAP3K8) 100622769(MAP3K5) 100624078 100627235 100739216(MAP3K15) 396617(MAP3K1)
CFR: 
102504523(MAP3K14) 102505073(MAP3K2) 102505358(MAP3K1) 102505759(MAP3K3) 102506410(MAP3K13) 102506717(MAP3K11) 102509143(MAP3K10) 102509815(MAP3K4) 102513589(MAP3K9) 102518335(MAP3K8) 102518433(MAP3K12) 102518953(MAP3K6) 102519538(MAP3K7) 102519731(MAP3K19) 102520465(MAP3K20) 102522243(MAP3K5) 102523391(MAP3K21) 106730942
BACU: 
102999255(MAP3K3) 102999328(MAP3K5) 103001072(MAP3K19) 103001803(MAP3K21) 103002185(MAP3K1) 103004845(MAP3K11) 103005548(MAP3K10) 103006512(MAP3K4) 103010611(MAP3K8) 103011832(MAP3K12) 103015628(MAP3K6) 103015859(MAP3K14) 103016499(MAP3K15) 103017845(MAP3K2) 103018600(MAP3K20) 103019037(MAP3K9) 103019299(MAP3K7) 103020592(MAP3K13)
LVE: 
103070441(MAP3K8) 103073201(MAP3K13) 103075340(MAP3K7) 103075844(MAP3K4) 103076636(MAP3K3) 103079692(MAP3K20) 103081325(MAP3K6) 103082490(MAP3K14) 103083140(MAP3K2) 103083385(MAP3K1) 103083922(MAP3K9) 103085713(MAP3K10) 103088930(MAP3K19) 103089110(MAP3K11) 103089504(MAP3K15) 103089656(MAP3K21)
ECB: 
100050140(MAP3K14) 100050587(MAP3K19) 100050628(MAP3K2) 100053153(MAP3K20) 100054289(MAP3K9) 100057319(MAP3K11) 100058153(MAP3K4) 100058434(MAP3K15) 100059237(MAP3K13) 100059834(MAP3K21) 100061688(MAP3K1) 100063602(MAP3K8) 100064002(MAP3K12) 100064751(MAP3K3) 100065841(MAP3K7) 100070933(MAP3K6) 100073186(MAP3K5)
MYB: 
102239254(MAP3K13) 102240442(MAP3K10) 102242281(MAP3K6) 102242308(MAP3K3) 102243445(MAP3K9) 102245865(MAP3K2) 102248363(MAP3K8) 102250231(MAP3K19) 102252114(MAP3K12) 102253871(MAP3K11) 102254118(MAP3K7) 102255496(MAP3K15) 102256847(MAP3K5) 102258632(MAP3K1) 102259842(MAP3K21) 102262247(MAP3K14) 102262729(MAP3K4) 102263045(MAP3K20)
MYD: 
102751509(MAP3K10) 102753581(MAP3K2) 102753720(MAP3K13) 102753749(MAP3K21) 102756379(MAP3K9) 102757393(MAP3K4) 102759312(MAP3K19) 102762787(MAP3K3) 102762988(MAP3K14) 102763786(MAP3K1) 102763957(MAP3K7) 102770852(MAP3K20) 102770934(MAP3K6) 102771069(MAP3K15) 102771311(MAP3K5) 102771577(MAP3K11) 102772527 102773021(MAP3K12) 102774051 102775461(MAP3K8)
HAI: 
109371277(MAP3K13) 109371823(MAP3K2) 109374683(MAP3K19) 109374860(MAP3K10) 109376677(MAP3K9) 109380266(MAP3K3) 109384179(MAP3K11) 109385622(MAP3K5) 109385705(MAP3K1) 109386678(MAP3K6) 109387711(MAP3K21) 109388733 109388741 109389111(MAP3K8) 109389465(MAP3K7) 109391825(MAP3K12) 109394013(MAP3K4) 109395015(MAP3K14) 109395649(MAP3K15)
PALE: 
102878894(MAP3K11) 102880315(MAP3K13) 102880422(MAP3K2) 102880725(MAP3K9) 102882452(MAP3K7) 102882855(MAP3K6) 102884946(MAP3K19) 102885138(MAP3K10) 102885530(MAP3K20) 102886741(MAP3K1) 102888506(MAP3K4) 102888994(MAP3K5) 102889570(MAP3K3) 102893121(MAP3K12) 102895694(MAP3K21) 102896654(MAP3K8) 102897183(MAP3K15) 102897751(MAP3K14)
LAV: 
100655149(MAP3K1) 100655585(MAP3K11) 100658813(MAP3K5) 100660454(MAP3K20) 100660700(MAP3K15) 100661927(MAP3K14) 100662122(MAP3K3) 100662383(MAP3K8) 100664871(MAP3K4) 100665139(MAP3K2) 100665212(MAP3K9) 100667170(MAP3K7) 100672580(MAP3K12) 100673821(MAP3K10) 100673872(MAP3K21) 100674925(MAP3K6) 100675161(MAP3K19) 100677466(MAP3K13)
MDO: 
100014185(MAP3K15) 100014282(MAP3K13) 100015818(MAP3K19) 100017378(MAP3K6) 100017495(MAP3K10) 100018494(MAP3K20) 100018684(MAP3K8) 100019975(MAP3K7) 100020082(MAP3K9) 100020668(MAP3K14) 100025970(MAP3K3) 100026735(MAP3K2) 100028987(MAP3K21) 100030111(MAP3K11) 100031527(MAP3K5) 100032065(MAP3K1) 100032495(MAP3K4)
SHR: 
100913571(MAP3K1) 100913706(MAP3K12) 100913796(MAP3K13) 100916246(MAP3K9) 100916713(MAP3K2) 100917439(MAP3K5) 100918124(MAP3K14) 100920997(MAP3K7) 100924042(MAP3K21) 100925633(MAP3K8) 100927077(MAP3K6) 100928208(MAP3K4) 100932009(MAP3K10) 100932862(MAP3K15) 100932989(MAP3K11) 100933129(MAP3K19) 100933813(MAP3K20) 100933837(MAP3K3)
OAA: 
GGA: 
100858193(MAP3K6) 101750513 107049111(MAP3K6) 418609(MAP3K15) 419954(MAP3K3) 419964(MAP3K14) 420419 420479(MAP3K8) 421579(MAP3K4) 421688(MAP3K5) 421808(MAP3K7) 424149(MAP3K20) 424225(MAP3K2) 424876(MAP3K13) 425792 427144(MAP3K1) 428586(MAP3K21) 429048(MAP3K19)
MGP: 
100538760(MAP3K14) 100539648(MAP3K21) 100539749(MAP3K7) 100540233(MAP3K19) 100541097(MAP3K8) 100542691 100542719(MAP3K3) 100543830(MAP3K2) 100547994(MAP3K13) 100548383(MAP3K4) 100550623(MAP3K1) 100550901(MAP3K9) 100551250(MAP3K5) 104911778 104914275(MAP3K6)
CJO: 
107306009(MAP3K1) 107306938(MAP3K12) 107308787 107308936(MAP3K8) 107311414(MAP3K21) 107311515(MAP3K4) 107311662(MAP3K5) 107311964(MAP3K7) 107314878(MAP3K9) 107316691(MAP3K20) 107316800(MAP3K2) 107316869(MAP3K19) 107317933(MAP3K13) 107324060(MAP3K6) 107325016(MAP3K14) 107325133(MAP3K3) 107325422(MAP3K15)
APLA: 
101791236(MAP3K14) 101791519(MAP3K15) 101791769(MAP3K8) 101792050(MAP3K13) 101793656 101795869 101795899(MAP3K4) 101796310(MAP3K9) 101798043(MAP3K2) 101798142(MAP3K19) 101799109(MAP3K5) 101800996(MAP3K7) 101801284(MAP3K3) 101801810(MAP3K21) 101803181 101803306(MAP3K20) 101803838
TGU: 
100217837(MAP3K14) 100219311(MAP3K15) 100219827(MAP3K2) 100221443(MAP3K7) 100223633(MAP3K3) 100224192(MAP3K5) 100225400(MAP3K13) 100225825(MAP3K1) 100226503 100228461(MAP3K20) 100228874(MAP3K21) 100229586(MAP3K9) 100229845(MAP3K4) 100230596(MAP3K8) 100232008(MAP3K19)
GFR: 
102032306(MAP3K3) 102033648(MAP3K2) 102033703(MAP3K20) 102034507(MAP3K5) 102034934(MAP3K9) 102035976(MAP3K8) 102038763(MAP3K14) 102038921(MAP3K15) 102039929(MAP3K7) 102040792(MAP3K13) 102041684(MAP3K21) 102041779(MAP3K19) 102043718(MAP3K4) 102044243 102044899(MAP3K1)
FAB: 
101807474(MAP3K12) 101807669(MAP3K1) 101810116(MAP3K20) 101810453(MAP3K15) 101811653(MAP3K2) 101812702(MAP3K9) 101812912(MAP3K13) 101813386(MAP3K14) 101813633(MAP3K19) 101813811(MAP3K5) 101813992(MAP3K3) 101814532(MAP3K7) 101814940(MAP3K4) 101816945(MAP3K21) 101817004 101819414(MAP3K8)
PHI: 
102101107(MAP3K4) 102102554(MAP3K20) 102102657(MAP3K11) 102103765(MAP3K1) 102104081(MAP3K5) 102106417(MAP3K21) 102107403(MAP3K7) 102108460 102111999(MAP3K9) 102112025(MAP3K13) 102112033(MAP3K3) 102112668(MAP3K19) 102113050(MAP3K2) 102113463(MAP3K14) 102113468(MAP3K12) 102113721(MAP3K15) 102114163(MAP3K8)
CCW: 
104683461(MAP3K9) 104684293(MAP3K21) 104684463(MAP3K4) 104686340(MAP3K15) 104686414 104686470(MAP3K8) 104686679(MAP3K1) 104689448(MAP3K5) 104692210(MAP3K7) 104693868(MAP3K20) 104693990(MAP3K2) 104694069(MAP3K19) 104696697(MAP3K13) 104698524(MAP3K14) 104698629(MAP3K3)
FPG: 
101910755(MAP3K20) 101911178(MAP3K1) 101911552(MAP3K5) 101911986(MAP3K6) 101912446(MAP3K3) 101914815(MAP3K21) 101915193(MAP3K15) 101916440(MAP3K13) 101917746(MAP3K7) 101918017(MAP3K4) 101918542(MAP3K9) 101919762(MAP3K14) 101921040(MAP3K8) 101921462(MAP3K2) 101921723(MAP3K12) 101922210(MAP3K19) 101923251 106112587
FCH: 
102045898(MAP3K1) 102046644(MAP3K12) 102047801(MAP3K3) 102048037(MAP3K4) 102048630(MAP3K14) 102050351 102050412(MAP3K13) 102051326(MAP3K20) 102052421(MAP3K21) 102052615(MAP3K15) 102052668(MAP3K2) 102055830(MAP3K8) 102057038(MAP3K5) 102057922(MAP3K9) 102058816(MAP3K7) 102059438(MAP3K19) 102060113(MAP3K6)
CLV: 
102085051(MAP3K5) 102085060(MAP3K3) 102085165(MAP3K20) 102086335(MAP3K9) 102086486(MAP3K4) 102087091(MAP3K8) 102087971(MAP3K15) 102088147 102088332(MAP3K14) 102088715(MAP3K12) 102089200(MAP3K21) 102089203(MAP3K19) 102091011(MAP3K13) 102092494(MAP3K2) 102097744(MAP3K1)
AAM: 
106486799(MAP3K4) 106487372(MAP3K21) 106489299 106489690(MAP3K7) 106489958(MAP3K8) 106490809(MAP3K15) 106493178(MAP3K13) 106493720(MAP3K10) 106494548 106494844 106495649(MAP3K14) 106496933 106497426(MAP3K3) 106497979(MAP3K5) 106498093(MAP3K9) 106498458(MAP3K19) 106498914(MAP3K1) 106499249(MAP3K20) 106499278(MAP3K2)
ASN: 
102368682(MAP3K15) 102368863 102369362(MAP3K19) 102371337(MAP3K11) 102374958(MAP3K3) 102375647(MAP3K20) 102375722(MAP3K5) 102376392(MAP3K12) 102376941(MAP3K1) 102379177(MAP3K6) 102379289(MAP3K2) 102380826(MAP3K21) 102381053(MAP3K13) 102381161 102382136(MAP3K4) 102382735(MAP3K9) 102386999(MAP3K7) 102387437(MAP3K8) 102388858(MAP3K14)
AMJ: 
102558220(MAP3K10) 102559099(MAP3K21) 102560853(MAP3K6) 102561424(MAP3K12) 102562794(MAP3K1) 102564788(MAP3K19) 102566049(MAP3K13) 102566471(MAP3K8) 102568383(MAP3K20) 102569201(MAP3K7) 102570911(MAP3K11) 102572648 102573024(MAP3K5) 102573918(MAP3K4) 102574412(MAP3K2) 102575720(MAP3K14) 106736664(MAP3K9) 106736858(MAP3K15) 106736961(MAP3K3)
PSS: 
102443925(MAP3K11) 102444358(MAP3K20) 102446659(MAP3K4) 102448094(MAP3K2) 102449623(MAP3K8) 102451227(MAP3K5) 102453748(MAP3K13) 102454634(MAP3K3) 102454787(MAP3K19) 102454880 102455384(MAP3K21) 102456989(MAP3K6) 102459971(MAP3K9) 102462962(MAP3K15) 102463619(MAP3K1) 102464024(MAP3K14)
CMY: 
102930570(MAP3K3) 102931859 102933894(MAP3K6) 102935713(MAP3K15) 102936034(MAP3K5) 102936052(MAP3K7) 102936228(MAP3K4) 102936511(MAP3K8) 102936755(MAP3K21) 102938448(MAP3K1) 102939329(MAP3K13) 102939834(MAP3K14) 102940369(MAP3K9) 102941356(MAP3K2) 102941563(MAP3K20) 102943511(MAP3K12) 102944746(MAP3K19) 102946051(MAP3K11)
CPIC: 
101931315(MAP3K7) 101932285(MAP3K14) 101932636(MAP3K9) 101933464(MAP3K1) 101934711(MAP3K2) 101939688(MAP3K11) 101939982(MAP3K13) 101940564(MAP3K20) 101940960(MAP3K15) 101941097(MAP3K8) 101942169(MAP3K19) 101942215(MAP3K6) 101943963(MAP3K5) 101946795(MAP3K4) 101948589 101948914(MAP3K12) 101950530(MAP3K10) 101951773(MAP3K21) 101953672(MAP3K3)
ACS: 
100551616(map3k5) 100552553(map3k6) 100553164(map3k12) 100554725(map3k7) 100556486(map3k9) 100557698(map3k3) 100558170(map3k2) 100558270(map3k13) 100558842(map3k21) 100560027(map3k4) 100560190(map3k14) 100561745(map3k1) 100562159 100562883(map3k8) 100565973(map3k10) 100566960(map3k20) 100568169(map3k15) 103279123(map3k19) 103280338
PBI: 
103048285(MAP3K1) 103049938(MAP3K2) 103051131(MAP3K11) 103052010(MAP3K5) 103053098(MAP3K13) 103053351(MAP3K12) 103054161(MAP3K20) 103059578(MAP3K4) 103060188 103061668(MAP3K21) 103061999(MAP3K15) 103064348(MAP3K8) 103064885 103065661(MAP3K6) 103066049(MAP3K14) 103066986(MAP3K3) 103067160(MAP3K9) 103067633(MAP3K7) 107326131
GJA: 
107107052(MAP3K20) 107107352(MAP3K21) 107107364(MAP3K10) 107107910(MAP3K8) 107113333(MAP3K4) 107114874(MAP3K7) 107115849(MAP3K15) 107116392 107116647(MAP3K6) 107117647 107117807(MAP3K2) 107119674(MAP3K12) 107121069(MAP3K11) 107122639(MAP3K9) 107122655(MAP3K19) 107123377(MAP3K1) 107123584(MAP3K13) 107125527(MAP3K14)
XLA: 
100113430(map3k12.S) 100126613(map3k4.S) 100337576(map3k12.L) 100337577(map3k13.S) 100337578(map3k13.L) 100381159(map3k9.L) 101027300 101027301 108699730(map3k9.S) 108700848(map3k14.L) 108701261(map3k2.L) 108701280(map3k19.L) 108701764 108702551(map3k14.S) 108702560 108702901(map3k2.S) 108702997 108704427(map3k1.S) 108708008 108708885 108717885 108718321(map3k1.L) 108718772(map3k8.L) 108719812 108719849(map3k8.S) 379399(map3k7.S) 398612(map3k10.L) 399459(map3k7.L) 734336(map3k3.L)
XTR: 
100101764(map3k7) 100488058(map3k10) 100488307(map3k12) 100488360 100488738(map3k19) 100488949(map3k9) 100489201(map3k14) 100490021(map3k3) 100490504(map3k1) 100493069(map3k8) 100493570(map3k2) 100493878(map3k13) 100495797(map3k20) 100497217(map3k4) 100497692(map3k5)
DRE: 
100004261(map3k14a) 100005496(si:ch211-1i11.3) 100334289(map3k15) 100334486(map3k1) 101886393 325488(map3k4) 404626(map3k12) 553788(map3k7) 555703(map3k5) 558321(map3k2) 559247(zak) 560211(map3k3) 560639(map3k9) 560932(map3k10) 561518(si:ch211-120p12.3) 563727(map3k8) 568412(si:ch211-45c16.2) 572217(map3k19) 795766(map3k14)
IPU: 
108256020(map3k3) 108256315(map3k15) 108256334 108256841(map3k7) 108257027(map3k5) 108259239 108260840(map3k4) 108260854 108263591 108263809 108264755(map3k10) 108265230(map3k12) 108266528(map3k19) 108266646(map3k20) 108266772(map3k13) 108268173 108271733 108272715(map3k2) 108274187(map3k8) 108277254(map3k1)
TRU: 
101061432(map3k5) 101061953 101062891(map3k9) 101063413(map3k13) 101063524(map3k7) 101064896(map3k20) 101067596(map3k14) 101068242(map3k10) 101068369 101069247(map3k8) 101069629 101069746(map3k2) 101070474 101071039 101072543(map3k3) 101074328(map3k19) 101075070(map3k21) 101076353(map3k15) 101076799(map3k4) 101078679 101079141(map3k11)
TNG: 
LCO: 
MZE: 
101463743(map3k13) 101463885(map3k11) 101464541(map3k2) 101468082(map3k3) 101468753(map3k14) 101468797 101472093 101472971(map3k9) 101473117(map3k5) 101475626 101475992 101477145(map3k10) 101478940(map3k12) 101481641 101482122 101484222(map3k8) 101484425(map3k20) 101484784(map3k15) 101484924(map3k7) 101485830(map3k4) 101485860(map3k19) 101486282
OLA: 
101156127 101156777(map3k15) 101159779(map3k8) 101160297(map3k2) 101160549(map3k12) 101160858(map3k20) 101161665(map3k10) 101162759 101164271(map3k7) 101166009(map3k11) 101166283 101166422 101167985 101168074 101168084(map3k19) 101169290(map3k3) 101169326(map3k9) 101170310(map3k13) 101172131 101174595 101174856(map3k4) 101175702(map3k5)
XMA: 
SASA: 
LCM: 
102346861(MAP3K5) 102347264 102350357 102350566(MAP3K2) 102351315(MAP3K14) 102352283(MAP3K6) 102353974(MAP3K3) 102355070(MAP3K1) 102356869(MAP3K9) 102356974(MAP3K19) 102358159(MAP3K7) 102358237(MAP3K15) 102362205(MAP3K12) 102364487(MAP3K11) 102364913(MAP3K20) 102366133(MAP3K4) 102367402(MAP3K13) 102367513(MAP3K8)
CMK: 
103175928(map3k4) 103176455(map3k20) 103177506(map3k15) 103177870(map3k1) 103178276(map3k7) 103178324(map3k5) 103178584(map3k9) 103179260(map3k21) 103180414(map3k19) 103186428(map3k8) 103187330 103187711(map3k3) 103189809(map3k2) 103189852 103190572(map3k13) 103190676(map3k12)
BFO: 
CIN: 
100174992 100177364 100179035 778675(mapkkk9/10/11) 778771(tak1/mapkkk7) 778975(mapkkk4) 778976(mltk)
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD12264(Dsim_GD12264) Dsimw501_GD18431(Dsim_GD18431) Dsimw501_GD19320(Dsim_GD19320) Dsimw501_GD20035(Dsim_GD20035) Dsimw501_GD20154(Dsim_GD20154) Dsimw501_GD27793(Dsim_GD27793)
DWI: 
DYA: 
Dyak_GE15342(Dyak_Tak1) Dyak_GE17470(dyak_GLEANR_18797) Dyak_GE22480(dyak_GLEANR_6151) Dyak_GE22767(dyak_GLEANR_6518) Dyak_GE25175(dyak_GLEANR_8804) Dyak_GE25632(dyak_GLEANR_9246)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
408533 409125(Mekk1) 410119 411566(MAPKKK9) 413809(Tak1)
BIM: 
BTER: 
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
BMOR: 
DPL: 
PXY: 
API: 
PHU: 
DPX: 
ISC: 
CEL: 
CELE_B0414.7(mtk-1) CELE_F33E2.2(dlk-1) CELE_F59A6.1(nsy-1) CELE_K11D12.10(mlk-1) CELE_R13F6.6(zak-1) CELE_Y105C5A.24(Y105C5A.24)
CBR: 
CBG02299(Cbr-nsy-1) CBG04061(Cbr-mtk-1) CBG08663(Cbr-mlk-1) CBG08707(Cbr-dlk-1) CBG16544(Cbr-zak-1)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
SMM: 
NVE: 
ADF: 
HMG: 
TAD: 
AQU: 
ATH: 
AT1G09000(NP1) AT1G63700(YDA) AT4G08480(MAPKKK9) AT4G08500(MEKK1) AT5G11850
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
VAR: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj0g3v0038859.1(Lj0g3v0038859.1) Lj0g3v0190659.1(Lj0g3v0190659.1) Lj0g3v0190659.2(Lj0g3v0190659.2) Lj0g3v0328679.1(Lj0g3v0328679.1) Lj1g3v4931570.1(Lj1g3v4931570.1) Lj2g3v0343910.1(Lj2g3v0343910.1) Lj4g3v0320510.1(Lj4g3v0320510.1) Lj4g3v0320510.2(Lj4g3v0320510.2) Lj4g3v0335750.1(Lj4g3v0335750.1) Lj5g3v0401650.1(Lj5g3v0401650.1) Lj5g3v1999000.1(Lj5g3v1999000.1) Lj6g3v1089020.2(Lj6g3v1089020.2) Lj6g3v2256790.1(Lj6g3v2256790.1)
LANG: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0001s09520g(POPTRDRAFT_709331) POPTR_0002s08950g(POPTRDRAFT_1071643) POPTR_0003s12910g(POPTRDRAFT_799954) POPTR_0005s16210g(POPTRDRAFT_1078383) POPTR_0006s24580g(POPTRDRAFT_717923) POPTR_0012s129501 POPTR_0012s129502 POPTR_0013s02360g(POPTRDRAFT_895121) POPTR_0015s12870g(POPTRDRAFT_902625) POPTR_0018s05140g(POPTRDRAFT_778792)
VVI: 
SLY: 
SPEN: 
SOT: 
INI: 
SIND: 
BVG: 
NNU: 
OSA: 
DOSA: 
Os02t0220700-01(Os02g0220700) Os02t0666300-01(Os02g0666300) Os03t0262200-00(Os03g0262200) Os03t0703400-01(Os03g0703400) Os04t0559800-01(Os04g0559800) Os08t0421800-01(Os08g0421800)
OBR: 
BDI: 
ATS: 
SBI: 
SORBI_01g010800(SORBIDRAFT_01g010800) SORBI_01g040360(SORBIDRAFT_01g040360) SORBI_04g007770(SORBIDRAFT_04g007770) SORBI_04g032420(SORBIDRAFT_04g032420) SORBI_06g025160(SORBIDRAFT_06g025160)
ZMA: 
100272734(cl17799_1) 100275358(GRMZM2G158860) 100279294(GRMZM2G044557) 100381765 100383481(GRMZM2G180555) 103625964(GRMZM2G130927) 103646082(GRMZM2G175504) 103654795
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
OLU: 
OTA: 
CVR: 
APRO: 
GSL: 
SCE: 
YCR073C(SSK22) YJL095W(BCK1) YLR362W(STE11) YNR031C(SSK2)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A05370(NCAS0A05370) NCAS_0A09470(NCAS0A09470) NCAS_0D04600(NCAS0D04600) NCAS_0J00960(NCAS0J00960)
NDI: 
NDAI_0G05470(NDAI0G05470) NDAI_0I00340(NDAI0I00340) NDAI_0J01990(NDAI0J01990)
TPF: 
TPHA_0B01010(TPHA0B01010) TPHA_0I00920(TPHA0I00920) TPHA_0M01840(TPHA0M01840)
TBL: 
TBLA_0A08290(TBLA0A08290) TBLA_0C02940(TBLA0C02940) TBLA_0I02400(TBLA0I02400)
TDL: 
TDEL_0A07560(TDEL0A07560) TDEL_0D01400(TDEL0D01400) TDEL_0E01710(TDEL0E01710)
KAF: 
KAFR_0A01420(KAFR0A01420) KAFR_0A06190(KAFR0A06190) KAFR_0C04590(KAFR0C04590) KAFR_0F04340(KAFR0F04340)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
NCU02234(mik-1) NCU03071(os-4) NCU06182(nrc-1)
NTE: 
NEUTE1DRAFT121976(NEUTE1DRAFT_121976) NEUTE1DRAFT86337(NEUTE1DRAFT_86337) NEUTE1DRAFT91407(NEUTE1DRAFT_91407)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1022184(AO090009000610) AOR_1_1162154(AO090003000662) AOR_1_520074(AO090038000313)
ANG: 
ANI_1_450074(An08g03240) ANI_1_456154(An17g01280) ANI_1_938024(An02g06830)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PAAG_00450 PAAG_03029 PAAG_12359(PAAG_07206) PAAG_12360(PAAG_07206)
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
PPL: 
DSQ: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT103706(AGABI1DRAFT_103706) AGABI1DRAFT117102(AGABI1DRAFT_117102) AGABI1DRAFT32645(AGABI1DRAFT_32645) AGABI1DRAFT68456(AGABI1DRAFT_68456)
ABV: 
AGABI2DRAFT140569(AGABI2DRAFT_140569) AGABI2DRAFT214884(AGABI2DRAFT_214884) AGABI2DRAFT62685(AGABI2DRAFT_62685) AGABI2DRAFT64355(AGABI2DRAFT_64355)
CPUT: 
SLA: 
WSE: 
WIC: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
MBR: 
SRE: 
DDI: 
DPP: 
DFA: 
DFA_02737(drkD)
EIV: 
TET: 
PTM: 
SMIN: 
v1.2.003218.t1(symbB.v1.2.003218.t1) v1.2.003218.t2(symbB.v1.2.003218.t2) v1.2.005256.t1(symbB.v1.2.005256.t1) v1.2.010154.t1(symbB.v1.2.010154.t1) v1.2.022894.t1(symbB.v1.2.022894.t1)
PIF: 
PSOJ: 
SPAR: 
EHX: 
GTT: 
NGR: 
 » show all
Taxonomy
Reference
1  [PMID:8940179]
  Authors
Wang XS, Diener K, Jannuzzi D, Trollinger D, Tan TH, Lichenstein H, Zukowski M, Yao Z.
  Title
Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase.
  Journal
J. Biol. Chem. 271 (1996) 31607-11.
  Sequence
[hsa:4217]
Reference
2  [PMID:11042189]
  Authors
Gotoh I, Adachi M, Nishida E.
  Title
Identification and characterization of a novel MAP kinase kinase kinase, MLTK.
  Journal
J. Biol. Chem. 276 (2001) 4276-86.
  Sequence
[hsa:51776] [mmu:65964]
Reference
3  [PMID:8334704]
  Authors
Vojtek AB, Hollenberg SM, Cooper JA.
  Title
Mammalian Ras interacts directly with the serine/threonine kinase Raf.
  Journal
Cell. 74 (1993) 205-14.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
146702-84-3

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