KEGG   ENZYME: 2.7.7.48Help
Entry
EC 2.7.7.48                 Enzyme                                 

Name
RNA-directed RNA polymerase;
RNA nucleotidyltransferase (RNA-directed);
RNA nucleotidyltransferase (RNA-directed);
RNA-dependent ribonucleate nucleotidyltransferase;
3D polymerase;
PB1 proteins;
PB2 proteins;
phage f2 replicase;
polymerase L;
Q-beta replicase;
phage f2 replicase;
ribonucleic acid replicase;
ribonucleic acid-dependent ribonucleate nucleotidyltransferase;
ribonucleic acid-dependent ribonucleic acid polymerase;
ribonucleic replicase;
ribonucleic synthetase;
RNA replicase;
RNA synthetase;
RNA transcriptase;
RNA-dependent ribonucleate nucleotidyltransferase;
RDRP;
RNA-dependent RNA polymerase;
RNA-dependent RNA replicase;
transcriptase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname
nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
Reaction(IUBMB)
nucleoside triphosphate + RNAn = diphosphate + RNAn+1 [RN:R00444]
Reaction(KEGG)
Substrate
nucleoside triphosphate [CPD:C00201];
RNAn [CPD:C00046]
Product
diphosphate [CPD:C00013];
RNAn+1 [CPD:C00046]
Comment
Catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. See also EC 2.7.7.6 DNA-directed RNA polymerase.
History
EC 2.7.7.48 created 1981, modified 1982
Orthology
K11699  
RNA-dependent RNA polymerase
Genes
BFO: 
ISC: 
TSP: 
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0006s17780g POPTR_0006s26980g(POPTRDRAFT_561891) POPTR_0007s06560g POPTR_0008s13520g(POPTRDRAFT_564678) POPTR_0008s13550g(POPTRDRAFT_820696) POPTR_0010s11560g(POPTRDRAFT_231683) POPTR_0015s08500g(POPTRDRAFT_575133) POPTR_0018s01670g(POPTRDRAFT_779035) POPTR_0303s002201 POPTR_0303s002202
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0197900-01(Os01g0197900) Os01t0198000-01(Os01g0198000) Os01t0527600-01(Os01g0527600) Os02t0736200-01(Os02g0736200) Os04t0465700-01(Os04g0465700)
OBR: 
BDI: 
SBI: 
SORBI_02g020722(SORBIDRAFT_02g020722) SORBI_03g002800(SORBIDRAFT_03g002800) SORBI_03g022060(SORBIDRAFT_03g022060) SORBI_03g022880(SORBIDRAFT_03g022880) SORBI_04g028630(SORBIDRAFT_04g028630) SORBI_06g001590(SORBIDRAFT_06g001590) SORBI_06g001600(SORBIDRAFT_06g001600) SORBI_06g019330(SORBIDRAFT_06g019330) SORBI_07g006150(SORBIDRAFT_07g006150) SORBI_10g025950(SORBIDRAFT_10g025950) SORBI_10g025970(SORBIDRAFT_10g025970)
ZMA: 
SITA: 
PDA: 
MUS: 
ATR: 
s00056p00110240(AMTR_s00056p00110240) s00078p00055040(AMTR_s00078p00055040) s00078p00056260(AMTR_s00078p00056260) s00088p00026960(AMTR_s00088p00026960) s00176p00039530(AMTR_s00176p00039530)
SMO: 
PPP: 
CSL: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_558084(AO090020000318)
ANG: 
ANI_1_2480094(An11g09540)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
PCO: 
SHS: 
ADL: 
LBC: 
CCI: 
SCM: 
SLA: 
DFA: 
DFA_00541(rrpB)
EHI: 
EHI_139420(171.t00022)
EDI: 
TET: 
PTM: 
PIF: 
EHX: 
NGR: 
GLA: 
 » show all
Taxonomy
Reference
1
  Authors
August, J.T., Cooper, S., Shapiro, L. and Zinder, N.D.
  Title
RNA phage induced RNA polymerase.
  Journal
Cold Spring Harbour Symp. Quant. Biol. 28 (1963) 95-97.
Reference
2  [PMID:14082356]
  Authors
HARUNA I, NOZU K, OHTAKA Y, SPIEGELMAN S
  Title
AN RNA "REPLICASE" INDUCED BY AND SELECTIVE FOR A VIRAL RNA: ISOLATION AND PROPERTIES.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 50 (1963) 905-11.
Reference
3  [PMID:13999778]
  Authors
WEISSMANN C, SIMON L, OCHOA S
  Title
Induction by an RNA phage of an enzyme catalyzing incorporation of ribonucleotides into ribonucleic acid.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 49 (1963) 407-14.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9026-28-2

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