KEGG   ENZYME: 2.8.2.2Help
Entry
EC 2.8.2.2                  Enzyme                                 

Name
alcohol sulfotransferase;
hydroxysteroid sulfotransferase;
3beta-hydroxy steroid sulfotransferase;
Delta5-3beta-hydroxysteroid sulfokinase;
3-hydroxysteroid sulfotransferase;
HST;
5alpha-androstenol sulfotransferase;
cholesterol sulfotransferase;
dehydroepiandrosterone sulfotransferase;
estrogen sulfokinase;
estrogen sulfotransferase;
steroid alcohol sulfotransferase;
steroid sulfokinase;
steroid sulfotransferase;
sterol sulfokinase;
sterol sulfotransferase;
alcohol/hydroxysteroid sulfotransferase;
3beta-hydroxysteroid sulfotransferase
Class
Transferases;
Transferring sulfur-containing groups;
Sulfotransferases
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate:alcohol sulfotransferase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate [RN:R00629]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
alcohol [CPD:C00069]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
alkyl sulfate [CPD:C02000]
Comment
Primary and secondary alcohols, including aliphatic alcohols, ascorbic acid, chloramphenicol, ephedrine and hydroxysteroids, but not phenolic steroids, can act as acceptors (cf. EC 2.8.2.15 steroid sulfotransferase).
History
EC 2.8.2.2 created 1961, modified 1980
Pathway
ec00140  Steroid hormone biosynthesis
Orthology
K01015  alcohol sulfotransferase
Genes
HSA: 6820(SULT2B1)
PTR: 747360(SULT2B1)
PPS: 100993458(SULT2B1)
GGO: 101129679(SULT2B1)
PON: 100441770(SULT2B1)
NLE: 100587860(SULT2B1)
MCC: 718739(SULT2B1)
MCF: 102147126(SULT2B1)
CSAB: 103234980(SULT2B1)
RRO: 104666566(SULT2B1)
RBB: 108523626(SULT2B1)
CJC: 100402576(SULT2B1) 108591642
SBQ: 101043923(SULT2B1)
MMU: 54200(Sult2b1)
RNO: 292915(Sult2b1)
CGE: 100753375 100774216(Sult2b1)
NGI: 103739992 103743615(Sult2b1)
HGL: 101723933(Sult2b1)
CCAN: 109682673(Sult2b1) 109692772
OCU: 100008957(SULT2B1) 100342351
TUP: 102477821(SULT2B1)
CFA: 484403(SULT2B1)
AML: 100480162(SULT2B1)
UMR: 103657236(SULT2B1)
ORO: 101377746(SULT2B1)
FCA: 101086863(SULT2B1)
PTG: 107180097(SULT2B1)
AJU: 106988649(SULT2B1)
BTA: 531192(SULT2B1)
BOM: 102284976(SULT2B1)
PHD: 102323269(SULT2B1)
CHX: 102183905(SULT2B1)
OAS: 101122543(SULT2B1)
SSC: 100626471(SULT2B1)
CFR: 102503575(SULT2B1)
CDK: 105102909(SULT2B1)
BACU: 103009833(SULT2B1)
LVE: 103078205(SULT2B1)
OOR: 101269222(SULT2B1)
ECB: 100147584(SULT2B1)
EPZ: 103540017(SULT2B1)
EAI: 106838308(SULT2B1)
MYB: 102258569(SULT2B1)
MYD: 102766101(SULT2B1)
HAI: 109391113(SULT2B1)
RSS: 109452512(SULT2B1)
PALE: 102887796(SULT2B1)
LAV: 100677254(SULT2B1)
TMU: 101357729
MDO: 100015166 100032213(SULT2B1)
SHR: 100915994 100933402(SULT2B1)
GGA: 426825(SULT2B1) 769841
CJO: 107319528 107325884(SULT2A1)
APLA: 101803633
ACYG: 106046522 106049358(SULT2B1)
GFR: 102038069
FAB: 101809344
PMAJ: 107209799
CCW: 104691854
FPG: 101922772
FCH: 102053558(SULT2B1)
CLV: 102089553(SULT2B1)
AAM: 106482022(SULT2B1) 106493165
XLA: 100036899(sult2b1.L) 100037047 108695914 108695915 108697829 108715412 432283(sult2b1.S) 447414(LOC100497264.L) 496246(sult2a1.L) 779257(sult5a1.L)
DRE: 777792(sult2st3)
CSEM: 103382275 103388296(sult1a4)
SME: SM_b21249
 » show all
Taxonomy
Reference
1  [PMID:6935986]
  Authors
Lyon ES, Jakoby WB.
  Title
The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases.
  Journal
Arch. Biochem. Biophys. 202 (1980) 474-81.
Reference
2  [PMID:6173569]
  Authors
Lyon ES, Marcus CJ, Wang JL, Jakoby WB.
  Title
Hydroxysteroid sulfotransferase.
  Journal
Methods. Enzymol. 77 (1981) 206-13.
Other DBs
ExplorEnz - The Enzyme Database: 2.8.2.2
IUBMB Enzyme Nomenclature: 2.8.2.2
ExPASy - ENZYME nomenclature database: 2.8.2.2
BRENDA, the Enzyme Database: 2.8.2.2
CAS: 9032-76-2

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