KEGG   ENZYME: 3.1.1.17Help
Entry
EC 3.1.1.17                 Enzyme                                 

Name
gluconolactonase;
lactonase;
aldonolactonase;
glucono-delta-lactonase;
gulonolactonase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
D-glucono-1,5-lactone lactonohydrolase
Reaction(IUBMB)
D-glucono-1,5-lactone + H2O = D-gluconate [RN:R01519]
Reaction(KEGG)
Substrate
D-glucono-1,5-lactone [CPD:C00198];
H2O [CPD:C00001]
Product
D-gluconate [CPD:C00257]
Comment
Acts on a wide range of hexose-1,5-lactones. The hydrolysis of L-gulono-1,5-lactone was previously listed separately.
History
EC 3.1.1.17 created 1961 (EC 3.1.1.18 created 1961, incorporated 1982)
Pathway
Pentose phosphate pathway
Ascorbate and aldarate metabolism
Caprolactam degradation
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Biosynthesis of antibiotics
Orthology
K01053  
gluconolactonase
Genes
HSA: 
9104(RGN)
PTR: 
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
705733(RGN)
MCF: 
CSAB: 
RRO: 
RBB: 
108522718(RGN)
CJC: 
100414860(RGN)
SBQ: 
101038710(RGN)
MMU: 
19733(Rgn)
RNO: 
25106(Rgn)
CGE: 
100752401(Rgn) 100755933
NGI: 
103726495(Rgn) 103750122
HGL: 
101714522(Rgn)
CCAN: 
109675701 109685603 109692107
OCU: 
100008619(RGN)
TUP: 
102474325(RGN)
CFA: 
480893(RGN)
AML: 
100467773(RGN)
UMR: 
103664924(RGN)
FCA: 
101096640(RGN)
PTG: 
102953980(RGN)
AJU: 
106972634(RGN)
BTA: 
280910(RGN)
BOM: 
102281821(RGN)
PHD: 
102324091(RGN)
CHX: 
102188205(RGN)
OAS: 
100171395(RGN)
SSC: 
768107(RGN)
CFR: 
102507973(RGN)
CDK: 
105101951(RGN)
BACU: 
103001487(RGN)
LVE: 
103086517(RGN)
ECB: 
100060684(RGN)
EPZ: 
103541294(RGN)
EAI: 
106847998(RGN)
MYB: 
102260518(RGN)
MYD: 
102752882(RGN)
HAI: 
109386423(RGN)
PALE: 
102896759(RGN)
LAV: 
100666857(RGN)
MDO: 
100010821
SHR: 
100934869(RGN)
OAA: 
100073972(RGN)
GGA: 
395480(RGN)
MGP: 
100549196(RGN)
CJO: 
107307715
APLA: 
101796441
ACYG: 
106035684(RGN)
TGU: 
100230441(RGN)
GFR: 
102035514
FAB: 
101812933
PHI: 
102113972
CCW: 
104686024(RGN)
FPG: 
101920914
FCH: 
102058317
CLV: 
102096126
AAM: 
106490874
ASN: 
102383173
AMJ: 
102564013(RGN)
PSS: 
102453303
CMY: 
102930029(Regucalcin) 102936132
CPIC: 
101941613
ACS: 
100568168(rgn)
PBI: 
103064686(RGN)
GJA: 
107110216
XLA: 
373659(rgn.L)
XTR: 
448549(rgn)
NPR: 
108801214(RGN)
DRE: 
403070(rgn)
SRX: 
107705518 107706673
SANH: 
107660123 107677606
SGH: 
107581344 107584804
IPU: 
100528098(rgn)
TRU: 
101075010(rgn)
TNG: 
GSTEN00020069G001
LCO: 
104934010(rgn)
NCC: 
104961844(rgn)
MZE: 
101464605(rgn)
OLA: 
101159881(rgn)
XMA: 
102217207(rgn)
CSEM: 
103391885(rgn)
LCF: 
108881118(rgn)
SASA: 
100196365(rgn) 106574967
ELS: 
105005821(rgn)
SFM: 
108933135(rgn)
LCM: 
102359731(RGN)
CMK: 
103177110(rgn)
BFO: 
BRAFLDRAFT_117110(Hip1) BRAFLDRAFT_216765 BRAFLDRAFT_63669 BRAFLDRAFT_63671 BRAFLDRAFT_63672
CIN: 
100184729
SPU: 
575038
SKO: 
100373805 100374112 100374265 102801234 102809260
AME: 
413627(GB18633)
BIM: 
100747180
BTER: 
100644382
NVI: 
100113493
TCA: 
656019
NVL: 
108568659
BMOR: 
101743375 101745880
DPL: 
KGM_204686
PXY: 
105389006 105396482
API: 
100165771
DNX: 
107168062 107168063
PHU: 
Phum_PHUM479620 Phum_PHUM584070
ISC: 
IscW_ISCW005090 IscW_ISCW010163 IscW_ISCW015725 IscW_ISCW022358 IscW_ISCW022359
TUT: 
107362627 107370621
LGI: 
LOTGIDRAFT_198219 LOTGIDRAFT_207903 LOTGIDRAFT_223508
CRG: 
105330682 105336643 105336644 105336648 105340850 105347299
OBI: 
106880375 106880392 106880394 106880395
LAK: 
106165631 106181504
NVE: 
NEMVE_v1g97576
ADF: 
107344854
TAD: 
TRIADDRAFT_54463
AQU: 
100631921 100640199 109580772
PPP: 
PHYPADRAFT_52282 PHYPADRAFT_63780 PHYPADRAFT_64195 PHYPADRAFT_94545
CSL: 
COCSUDRAFT_39799 COCSUDRAFT_8290
CVR: 
CHLNCDRAFT_136730
GSL: 
Gasu_37460
NCR: 
NCU01866
NTE: 
NEUTE1DRAFT53848(NEUTE1DRAFT_53848)
SMP: 
SMAC_06848
PAN: 
PODANSg3564
TTT: 
THITE_2046186 THITE_70175
CTHR: 
CTHT_0011110
MGR: 
MGG_05984 MGG_09681
TMN: 
UCRPA7_2620 UCRPA7_3427 UCRPA7_4389
FGR: 
FGSG_03393 FGSG_03816 FGSG_10339 FGSG_10675
FPU: 
FPSE_04558 FPSE_05702 FPSE_09024 FPSE_10628
FVR: 
FVEG_03063 FVEG_10940 FVEG_12910
FOX: 
FOXG_04675 FOXG_05070 FOXG_12377 FOXG_16906
NHE: 
NECHADRAFT_45251 NECHADRAFT_51180 NECHADRAFT_78471 NECHADRAFT_97553
TRE: 
TRIREDRAFT_62581
MAW: 
MAC_02947 MAC_09343
MAJ: 
MAA_04963 MAA_07730
CMT: 
CCM_06360
VAL: 
VDBG_08613
VDA: 
VDAG_08282
CFJ: 
CFIO01_04090 CFIO01_04106 CFIO01_07919 CFIO01_08322 CFIO01_09202 CFIO01_10442 CFIO01_12614 CFIO01_13063
ELA: 
UCREL1_1344
PFY: 
PFICI_06514 PFICI_10354
SSL: 
SS1G_04903 SS1G_13841
BFU: 
BC1G_08757 BC1G_15612
MBE: 
MBM_02070 MBM_05171
PSCO: 
LY89DRAFT_647253 LY89DRAFT_685065 LY89DRAFT_706484 LY89DRAFT_722871
GLZ: 
GLAREA_09440
ANI: 
AN8977.2
AOR: 
AOR_1_2104(AO090124000002) AOR_1_88174(AO090005000049) AOR_1_890114(AO090701000487)
ANG: 
ANI_1_106174(An10g00900) ANI_1_254044(An05g02030)
AFV: 
AFLA_059570 AFLA_072910 AFLA_090000
NFI: 
NFIA_095940
PCS: 
Pc16g12050
PDP: 
PDIP_15110 PDIP_67450
CIM: 
CIMG_06231
CPW: 
CPC735_027670
PBL: 
PAAG_07354
PBN: 
PADG_05855
ABE: 
ARB_07013
TVE: 
TRV_06456
AJE: 
HCAG_03025
PNO: 
SNOG_09892 SNOG_12135 SNOG_12409
PTE: 
PTT_07298 PTT_09334 PTT_18952
BZE: 
COCCADRAFT_109740 COCCADRAFT_1851 COCCADRAFT_39274
BSC: 
COCSADRAFT_36639 COCSADRAFT_36796 COCSADRAFT_37253
BOR: 
COCMIDRAFT_104527 COCMIDRAFT_36883 COCMIDRAFT_7750
ZTR: 
MYCGRDRAFT_17006 MYCGRDRAFT_43806 MYCGRDRAFT_66984
PFJ: 
MYCFIDRAFT_119346 MYCFIDRAFT_131699 MYCFIDRAFT_58890
BCOM: 
BAUCODRAFT_155122
NPA: 
UCRNP2_707 UCRNP2_7267 UCRNP2_7325
CNE: 
CNJ01840
CNB: 
CNBJ1630
CGI: 
CGB_I2490W
TMS: 
TREMEDRAFT_73199
PPL: 
POSPLDRAFT_107554
TVS: 
TRAVEDRAFT_50621
DSQ: 
DICSQDRAFT_60009
PCO: 
PHACADRAFT_246592
SHS: 
STEHIDRAFT_138260 STEHIDRAFT_45584
HIR: 
HETIRDRAFT_430154
PSQ: 
PUNSTDRAFT_46818
ADL: 
AURDEDRAFT_136790 AURDEDRAFT_83599
FME: 
FOMMEDRAFT_164641 FOMMEDRAFT_25046
GTR: 
GLOTRDRAFT_81248
LBC: 
LACBIDRAFT_248522
MPR: 
MPER_03344
MRR: 
Moror_10434
SCM: 
SCHCODRAFT_61623 SCHCODRAFT_61940
ABP: 
AGABI1DRAFT115575(AGABI1DRAFT_115575) AGABI1DRAFT130338(AGABI1DRAFT_130338) AGABI1DRAFT77188(AGABI1DRAFT_77188)
ABV: 
AGABI2DRAFT188135(AGABI2DRAFT_188135) AGABI2DRAFT194493(AGABI2DRAFT_194493) AGABI2DRAFT195324(AGABI2DRAFT_195324)
CPUT: 
CONPUDRAFT_159165 CONPUDRAFT_159166
SLA: 
SERLADRAFT_478326
WSE: 
WALSEDRAFT_31518
WIC: 
J056_003839
UMA: 
UMAG_05603
PFP: 
PFL1_01012
FCY: 
FRACYDRAFT_235169
PIF: 
PITG_02129 PITG_04624 PITG_21468
PSOJ: 
PHYSODRAFT_251626 PHYSODRAFT_251645 PHYSODRAFT_319344
EHX: 
EMIHUDRAFT_211448 EMIHUDRAFT_240728 EMIHUDRAFT_254182 EMIHUDRAFT_435448 EMIHUDRAFT_446776 EMIHUDRAFT_461722
ESC: 
Entcl_0164
KLE: 
AO703_20615
ENR: 
H650_14545
ENF: 
AKI40_0109
KPN: 
KPN_03982
KPU: 
KP1_5335
KPP: 
A79E_0132
KPK: 
A593_10130
KPZ: 
KPNIH27_24555
KPV: 
KPNIH29_25465
KPT: 
VK055_3487
KPE: 
KPK_0112
KPO: 
KPN2242_22980
KPR: 
KPR_4931
KPX: 
PMK1_01487(gnl)
KVA: 
Kvar_0118
KVD: 
KR75_07525
KVQ: 
SP68_14100
ROR: 
RORB6_19625
RON: 
TE10_01340
KSA: 
C813_16035
KCO: 
BWI95_08365
KIN: 
AB182_26305
PSTS: 
E05_05270(gnl)
YIN: 
CH53_4237
SPE: 
Spro_3932
SRR: 
SerAS9_4138
SRL: 
SOD_c38920(gnl)
SRY: 
M621_20895
SPLY: 
Q5A_020875(gnl)
SRS: 
SerAS12_4139
SRA: 
SerAS13_4139
SMAF: 
D781_1530
SMAC: 
SMDB11_3330
SLQ: 
M495_20530
SFW: 
WN53_21575
SFG: 
AV650_17365
SRZ: 
AXX16_3565
SFO: 
Z042_06780
PCT: 
PC1_3691
PWA: 
Pecwa_3888
PPAR: 
A8F97_22065
PEC: 
W5S_4034
PWS: 
A7983_04495
ETA: 
ETA_33580
EPY: 
EpC_35620(gnl)
EPR: 
EPYR_03831(gnl)
EAM: 
EAMY_3566(gnl)
ERJ: 
EJP617_10490(gnl)
PAM: 
PANA_0366(gnl) PANA_2953(gnl)
PLF: 
PANA5342_1092 PANA5342_4048(gnl)
PAJ: 
PAJ_2225(gnl) PAJ_3521(gnl)
PAQ: 
PAGR_g1085 PAGR_g3912
PVA: 
Pvag_pPag30408
PAO: 
Pat9b_1876
PAGG: 
AL522_12120
TCI: 
A7K98_02605
XBV: 
XBW1_2079
EHO: 
A9798_02095
HSO: 
HS_0766
HSM: 
HSM_1233
PMU: 
PM1248
PMV: 
PMCN06_1912(gnl)
PUL: 
NT08PM_2218
PMP: 
Pmu_19080(gnl)
PMUL: 
DR93_491
MSU: 
MS0684
MHT: 
D648_290
MHQ: 
D650_460
MHAT: 
B824_1230
MHX: 
MHH_c05630(gnl)
MHAE: 
F382_07995
MHAM: 
J450_07100
MHAO: 
J451_07975
MHAL: 
N220_00070
MHAQ: 
WC39_00225
MHAY: 
VK67_00230
APL: 
APL_1565
APJ: 
APJL_1595
APA: 
APP7_1627
ASU: 
Asuc_1854
ASI: 
ASU2_09995
ASS: 
ASU1_10040
XFA: 
XF_1297
XFT: 
PD_0548
XFM: 
Xfasm12_0622
XFN: 
XfasM23_0573
XFF: 
XFLM_08220
XFL: 
P303_02300
XFS: 
D934_03965
XFH: 
XFHB_09230
XCC: 
XCC3591(GNL) XCC4113(gnl)
XCB: 
XC_0553 XC_4205
XCA: 
xcc-b100_0569(gnl1) xcc-b100_4320(gnl3)
XCP: 
XCR_3966 XCR_4434
XCV: 
XCV0577(gnl) XCV4353(gnl1)
XAC: 
XAC0548(GNL) XAC4248(gnl)
XCI: 
XCAW_00049(gnl) XCAW_00961(gnl)
XCT: 
J151_00670 J151_04429
XCU: 
J159_00667 J159_04378
XCN: 
J169_00666 J169_04426
XCW: 
J162_00666 J162_04384
XCR: 
J163_00666 J163_04379
XCM: 
J164_00666 J164_04379
XCF: 
J172_00661 J172_04419
XCJ: 
J158_00667 J158_04382
XFU: 
XFF4834R_chr05430 XFF4834R_chr41210
XAX: 
XACM_0537(gnl) XACM_4121(gnl)
XAO: 
XAC29_02790 XAC29_21430
XOO: 
XOO4276(gnl)
XOM: 
XOO4033(XOO4033)
XOP: 
PXO_03689
XOY: 
AZ54_02590
XOR: 
XOC_0624
XTN: 
FD63_19390
XFR: 
BER92_17465
XGA: 
BI317_01510
XVE: 
BJD12_11895 BJD12_15365
XPE: 
BJD13_14140 BJD13_17710
PSU: 
Psesu_2945
PSUW: 
WQ53_08845
LAB: 
LA76x_4476
LAQ: 
GLA29479_2521
LGU: 
LG3211_0619
FAU: 
Fraau_2492
VTU: 
IX91_17635
VGA: 
BSQ33_11670
AWD: 
AWOD_II_0053
PMK: 
MDS_3449
PPT: 
PPS_1791
PPUH: 
B479_13050
PPUD: 
DW66_2038
PFV: 
Psefu_1766
PMON: 
X969_06790
PMOT: 
X970_06765
POR: 
APT59_01065 APT59_05610 APT59_07775 APT59_12360 APT59_14450
PST: 
PSPTO_1345(gnl) PSPTO_2470
PSB: 
Psyr_0764 Psyr_2235
PSYR: 
N018_10360 N018_19870 N018_21850
PSP: 
PSPPH_2952
PCI: 
PCH70_25810
PFO: 
Pfl01_2803
PFS: 
PFLU_3458
PFE: 
PSF113_2201
PFW: 
PF1751_v1c28910
PFF: 
PFLUOLIPICF721730
PTV: 
AA957_27760
PCG: 
AXG94_02725 AXG94_05250
PSA: 
PST_1621(gnl)
PSZ: 
PSTAB_1531
PSR: 
PSTAA_1650(gnl)
PSH: 
Psest_2755
PSTT: 
CH92_09490 CH92_09800
PBA: 
PSEBR_a3540
PBC: 
CD58_11315
PPUU: 
PputUW4_03011
PSK: 
U771_18480
PFZ: 
AV641_10090
PRH: 
LT40_15355
PPSY: 
AOC04_06955
ACC: 
BDGL_001218(drp35)
ACI: 
ACIAD2819
ACV: 
AMD27_07920
ALA: 
BFG52_08580
COLW: 
A3Q33_17425 A3Q33_18080
PAT: 
Patl_2641
PBW: 
D172_007480 D172_009475
GAG: 
Glaag_1633
GPS: 
C427_4806
CJA: 
CJA_2000(gnl)
CEB: 
B0D95_04640
CELL: 
CBR65_02265
TTU: 
TERTU_0525
SAGA: 
M5M_17015
MDN: 
JT25_022515
MDH: 
AYM39_07815
NWA: 
Nwat_2638
GAI: 
IMCC3135_00795(gnl_1) IMCC3135_09610(gnl_2) IMCC3135_20930(gnl_3)
CSA: 
Csal_2779
HEL: 
HELO_1553(gnl)
HAK: 
KO116_00077 KO116_01615
HAM: 
HALO1682
HHU: 
AR456_03970 AR456_05305
HAA: 
A5892_00950
KUS: 
B9G99_09070 B9G99_13530
KMA: 
B9H00_01460 B9H00_05785 B9H00_12330
ADI: 
B5T_01627
AXE: 
P40_07665
MME: 
Marme_3898
MARS: 
A8C75_12565
PSPI: 
PS2015_134
RSO: 
RSp0824
RSN: 
RSPO_m01142
RSE: 
F504_4395
RPI: 
Rpic_3985 Rpic_4042
RPF: 
Rpic12D_4098 Rpic12D_4154
RPJ: 
N234_26310
RMN: 
TK49_18950
RIN: 
ACS15_1399 ACS15_5729 ACS15_5807
REU: 
Reut_B4613
REH: 
H16_A3012(gnl1) H16_B0345(gnl2) H16_B1441(gnl3)
CNC: 
CNE_1c29660(gnl) CNE_2c03890(gnl)
CTI: 
RALTA_B1942
CBW: 
RR42_m2004 RR42_s0543 RR42_s1186 RR42_s1289
CGD: 
CR3_4201
CCUP: 
BKK81_24895
BMA: 
BMAA0036
BMV: 
BMASAVP1_1190
BML: 
BMA10229_1470 BMA10229_1473
BMN: 
BMA10247_A0046
BMAL: 
DM55_3660 DM55_3663
BMAE: 
DM78_4535
BMAQ: 
DM76_4356 DM76_4359
BMAI: 
DM57_05190
BMAF: 
DM51_3814
BMAZ: 
BM44_3619 BM44_3623
BMAB: 
BM45_4397 BM45_4400
BPS: 
BPSS0035
BPM: 
BURPS1710b_A1542
BPL: 
BURPS1106A_A0044
BPD: 
BURPS668_A0058
BPSE: 
BDL_5867
BPSM: 
BBQ_3709
BPSU: 
BBN_5891
BPSD: 
BBX_5036
BPZ: 
BP1026B_II0036
BPQ: 
BPC006_II0044
BPK: 
BBK_5174
BPSH: 
DR55_5336
BPSA: 
BBU_3597
BPSO: 
X996_5106
BUT: 
X994_4656
BTD: 
BTI_4717
BOK: 
DM82_3919
BOC: 
BG90_4109
BCN: 
Bcen_5466
BCH: 
Bcen2424_5396
BCM: 
Bcenmc03_4874
BCJ: 
BCAM2586
BCEN: 
DM39_4197
BCEW: 
DM40_4970
BCEO: 
I35_6484
BMU: 
Bmul_4704
BMK: 
DM80_3903
BMUL: 
NP80_4828
BCED: 
DM42_5386
BCEP: 
APZ15_23485
BCON: 
NL30_16770
BLAT: 
WK25_27330
BSEM: 
WJ12_31235
BPSL: 
WS57_12875
BMEC: 
WJ16_18610
BGP: 
BGL_2c15030
BUG: 
BC1001_0567 BC1001_4344 BC1001_4435
BGE: 
BC1002_4601 BC1002_5581
BGF: 
BC1003_3554 BC1003_5058 BC1003_5936
BGD: 
bgla_1g13960 bgla_2g26700
BGO: 
BM43_2735 BM43_6422
BYI: 
BYI23_B002640 BYI23_C003800 BYI23_C005760 BYI23_C005950 BYI23_C012410 BYI23_D003050
BUO: 
BRPE64_BCDS10790 BRPE64_CCDS02980 BRPE64_CCDS03350 BRPE64_CCDS03860
BUE: 
BRPE67_BCDS05070 BRPE67_CCDS05510 BRPE67_CCDS05700 BRPE67_CCDS08400 BRPE67_CCDS14180 BRPE67_DCDS04850
BUL: 
BW21_4246
BUQ: 
AC233_27550 AC233_27785
BPLA: 
bpln_2g15750
BUD: 
AQ610_19680
BXE: 
Bxe_B0611 Bxe_B2153 Bxe_C0969
BXB: 
DR64_4482 DR64_5942 DR64_7483
BPH: 
Bphy_4442 Bphy_5161 Bphy_6029
BPX: 
BUPH_00923 BUPH_01006 BUPH_04451
BPY: 
Bphyt_4278
BFN: 
OI25_5028 OI25_6061 OI25_6303 OI25_7920
BCAI: 
K788_0001706 K788_0007678
PSPW: 
BJG93_23185 BJG93_30060
BPAR: 
BN117_0680 BN117_3740
BBR: 
BB1048
BBM: 
BN115_0696 BN115_0998
BBH: 
BN112_2399 BN112_2713
BBX: 
BBS798_0700 BBS798_1018
BPT: 
Bpet0732 Bpet2682 Bpet4150
BHO: 
D560_1644
BHM: 
D558_1632
BHZ: 
ACR54_01178(gnl)
BBRO: 
BAU06_00330 BAU06_03510 BAU06_05795 BAU06_06645 BAU06_09730 BAU06_12995 BAU06_17530
BFZ: 
BAU07_00205 BAU07_08700 BAU07_10785 BAU07_13530 BAU07_19600 BAU07_20700 BAU07_22260 BAU07_22900
BPDZ: 
BBN53_13470
AXY: 
AXYL_04712
AXO: 
NH44784_048191 NH44784_057311 NH44784_058721
AXN: 
AX27061_2973 AX27061_3989
AXS: 
LH59_13995 LH59_18350
AXX: 
ERS451415_02950(gnl_1) ERS451415_04009
ADT: 
APT56_18650
AIS: 
BUW96_01830 BUW96_16155
AKA: 
TKWG_03875 TKWG_17280
AMIM: 
MIM_c00330 MIM_c02510 MIM_c06000 MIM_c12250(gnl1) MIM_c19970(gnl2) MIM_c20340 MIM_c34540(gnl3)
RHY: 
RD110_01595 RD110_07710 RD110_13800 RD110_22610
POL: 
Bpro_4512
PNA: 
Pnap_0570
AAV: 
Aave_2596
AJS: 
Ajs_1999
DIA: 
Dtpsy_1798
AAA: 
Acav_1615 Acav_2152 Acav_2607 Acav_4662
ACK: 
C380_13035
ACRA: 
BSY15_135
ACID: 
CBP33_05890
VEI: 
Veis_1531 Veis_3148
DAC: 
Daci_0257 Daci_2283 Daci_4272
DEL: 
DelCs14_2577 DelCs14_4364
DTS: 
BI380_07125 BI380_12830
DHK: 
BO996_19060
VAP: 
Vapar_0705 Vapar_3342 Vapar_5446
VPE: 
Varpa_0801 Varpa_1476 Varpa_1904 Varpa_2275 Varpa_4397
VPD: 
VAPA_1c05360 VAPA_1c07610 VAPA_1c39240 VAPA_2c03050
VAA: 
AX767_02315 AX767_04485
ADN: 
Alide_0353
ADK: 
Alide2_0298
RTA: 
Rta_17730
LIM: 
L103DPR2_01028(gnl)
DPY: 
BA022_05095
HSE: 
Hsero_4020 Hsero_4455
HSZ: 
ACP92_20070 ACP92_22245
HHT: 
F506_22205
HRB: 
Hrubri_3221 Hrubri_4460
CPRA: 
CPter91_0445
LCH: 
Lcho_0714 Lcho_1111
RGU: 
A4W93_05235
PBH: 
AAW51_3073
AZO: 
azo2341(gnl)
BPRC: 
D521_0582
BEB: 
AEM42_02525
BEBA: 
BWI17_00190 BWI17_07350 BWI17_21115
HBI: 
HBZC1_16860
HHM: 
BN341_18400
SCL: 
sce8236(gnl2)
SCU: 
SCE1572_35875 SCE1572_47095
CCRO: 
CMC5_059530
SAMY: 
DB32_008325
LLU: 
AKJ09_05910 AKJ09_05914 AKJ09_08483
MRM: 
A7982_04183
HOH: 
Hoch_5570
MLO: 
mll4328
MLN: 
A9174_04955 A9174_30155 A9174_30485
MCI: 
Mesci_0975 Mesci_1066
MOP: 
Mesop_1010 Mesop_2881
MAM: 
Mesau_01043
MAMO: 
A6B35_02690 A6B35_02935 A6B35_03365 A6B35_30855
MESO: 
BSQ44_07880
MESW: 
A9K65_005040 A9K65_005515
MES: 
Meso_3770
PLA: 
Plav_2454
SME: 
SM_b20453 SMa0196
SMK: 
Sinme_3731 Sinme_5391
SMQ: 
SinmeB_4227 SinmeB_5508
SMX: 
SM11_pC1637 SM11_pD1173
SMI: 
BN406_04976 BN406_06225
SMEG: 
C770_GR4pC1330 C770_GR4pD1162
SMEL: 
SM2011_a0196 SM2011_b20453
SMER: 
DU99_24895 DU99_31065
SMD: 
Smed_5316
RHI: 
NGR_b22240(gnl)
SFH: 
SFHH103_05008(gnl)
SFD: 
USDA257_c24740(gnl1) USDA257_c25090(gnl2)
SIX: 
BSY16_4632 BSY16_5303
SAME: 
SAMCFNEI73_pC0284(gnl)
EAD: 
OV14_b0830(gnl)
EAH: 
FA04_29120
ATU: 
Atu4029
ARA: 
Arad_0839 Arad_8419 Arad_9676
ATF: 
Ach5_38100
ATA: 
AWN88_05690
AVI: 
Avi_5723
AGR: 
AGROH133_12758
AGC: 
BSY240_2225 BSY240_2808
ARO: 
B0909_17615
RET: 
RHE_CH03704 RHE_PC00140 RHE_PF00485
REC: 
RHECIAT_CH0003978
REL: 
REMIM1_CH03782 REMIM1_PB00155 REMIM1_PF00390
REI: 
IE4771_CH04032 IE4771_PE00556 IE4771_PE00592
REP: 
IE4803_CH04091 IE4803_PD00541 IE4803_PD00577
RLE: 
RL4240 pRL100387 pRL120288
RLT: 
Rleg2_3486 Rleg2_4507 Rleg2_5734
RLG: 
Rleg_3774 Rleg_4647 Rleg_6418
RLB: 
RLEG3_02150 RLEG3_06935 RLEG3_29905
RLU: 
RLEG12_02425 RLEG12_05485 RLEG12_28745
RTR: 
RTCIAT899_CH03145 RTCIAT899_PC05420 RTCIAT899_PC05735
RIR: 
BN877_II1156
RHL: 
LPU83_3729
RGA: 
RGR602_CH03614 RGR602_PC00533 RGR602_PC00688
RHN: 
AMJ98_CH03940 AMJ98_PB00197 AMJ98_PE00562
RPHA: 
AMC79_CH03908 AMC79_PA00151 AMC79_PA00239
RHT: 
NT26_3230
RHX: 
AMK02_CH03826 AMK02_PB00211 AMK02_PD00429
NGL: 
RG1141_PA09080 RG1141_PA12980
NGG: 
RG540_PA08060 RG540_PA13970
SHZ: 
shn_26155 shn_32750
OAN: 
Oant_3913
OAH: 
DR92_4348
OPS: 
A8A54_14980
BJA: 
bll2172 bll2817 bll2956 bll3369 bll6697 blr2277 blr6437
BJU: 
BJ6T_03340 BJ6T_27230 BJ6T_30140 BJ6T_63770 BJ6T_68090 BJ6T_69450 BJ6T_69530 BJ6T_76800
BJP: 
RN69_01605 RN69_13285 RN69_14715 RN69_30900 RN69_33030 RN69_33700 RN69_33740 RN69_37280
BRA: 
BRADO2487 BRADO2582 BRADO3863 BRADO4769 BRADO5762 BRADO6760
BBT: 
BBta_2832 BBta_2929 BBta_4803 BBta_6274 BBta_6492
BRS: 
S23_16070 S23_18910 S23_45340 S23_50560 S23_51800 S23_51880
AOL: 
S58_17890 S58_18530 S58_29060 S58_39140 S58_50310 S58_51280
BRC: 
BCCGELA001_09525 BCCGELA001_10690 BCCGELA001_12620 BCCGELA001_12660 BCCGELA001_13255 BCCGELA001_15025
BRAD: 
BF49_1312 BF49_1373 BF49_1736 BF49_1865 BF49_1866 BF49_1874 BF49_4948 BF49_5226
BIC: 
LMTR13_06220 LMTR13_06850 LMTR13_28510 LMTR13_29050 LMTR13_31930
BRO: 
BRAD285_1543 BRAD285_2486 BRAD285_3508 BRAD285_4754 BRAD285_4864 BRAD285_5841
RPA: 
RPA3624
RPB: 
RPB_1903
RPC: 
RPC_2719
RPD: 
RPD_3465
RPE: 
RPE_2028
RPT: 
Rpal_4144
RPX: 
Rpdx1_1725
BOP: 
AXW83_02255 AXW83_04750 AXW83_12470 AXW83_12575
BOS: 
BSY19_1723 BSY19_1889 BSY19_2408
BVV: 
BHK69_03455 BHK69_13705 BHK69_27350
XAU: 
Xaut_4321
AZC: 
AZC_1557
SNO: 
Snov_3672
MEX: 
Mext_0612
MEA: 
Mex_1p0437(gnl)
MDI: 
METDI0591(gnl)
MCH: 
Mchl_0623
MRD: 
Mrad2831_0597 Mrad2831_4136 Mrad2831_5415 Mrad2831_5439 Mrad2831_6221
MET: 
M446_0609 M446_5618
MPO: 
Mpop_0588 Mpop_1059
MNO: 
Mnod_2253
MOR: 
MOC_0760 MOC_2521 MOC_5990 MOC_6015
META: 
Y590_02100
MAQU: 
Maq22A_2p40390 Maq22A_2p40765 Maq22A_2p41870 Maq22A_c16555 Maq22A_c26495 Maq22A_c26690
BID: 
Bind_3069
CHEL: 
AL346_18240 AL346_18545
CDQ: 
BOQ54_10020
DEQ: 
XM25_14920
RHZ: 
RHPLAN_06690 RHPLAN_06700 RHPLAN_25030
MEY: 
TM49_22120
MAAD: 
AZF01_21170
MMED: 
Mame_01363(gnl)
AUA: 
M673_08940 M673_17745 M673_20615
MCG: 
GL4_1419
PSIN: 
CAK95_00840
RBM: 
TEF_17940 TEF_18810
CCR: 
CC_1224 CC_2128
CCS: 
CCNA_01282 CCNA_02212
CAK: 
Caul_0625 Caul_3389
CSE: 
Cseg_1291 Cseg_2660
CHQ: 
AQ619_10205 AQ619_11955
PZU: 
PHZ_c0815
BRD: 
JL11_13080
BRL: 
BZG35_09830
AEX: 
Astex_1928
CBOT: 
ATE48_15690
SIL: 
SPO2559(gnl) SPOA0241
RDE: 
RD1_0868(gnl) RD1_3716(gnl)
RLI: 
RLO149_c007140 RLO149_c037910
PYE: 
A6J80_00945
PTP: 
RCA23_c24630
CID: 
P73_2059
MALG: 
MALG_04496
PPHR: 
APZ00_12335 APZ00_20560
LAGG: 
B0E33_29140
YAN: 
AYJ57_19965
SUAM: 
BOO69_11015
TPRO: 
Ga0080559_TMP4109
TOM: 
BWR18_19910
PABY: 
Ga0080574_TMP463
LVS: 
LOKVESSMR4R_01072(gnl)
MMR: 
Mmar10_2728
HNE: 
HNE_0464
HBA: 
Hbal_3079
HBC: 
AEM38_11290
ZMO: 
ZMO1649
ZMN: 
Za10_1568
ZMB: 
ZZ6_1466
ZMI: 
ZCP4_1511
ZMC: 
A265_01511(gnl)
ZMR: 
A254_01510(gnl)
ZMP: 
Zymop_1466
NPP: 
PP1Y_AT20032
NPN: 
JI59_08660 JI59_17395
NRE: 
BES08_20505 BES08_27050
SAL: 
Sala_2118
SPHK: 
SKP52_06135 SKP52_17310
SPHP: 
LH20_07310 LH20_13275 LH20_13605
SMAG: 
AN936_01810 AN936_08120 AN936_12125
SMAZ: 
LH19_01925 LH19_08265 LH19_13370 LH19_26520 LH19_26650
STER: 
AOA14_05215 AOA14_11130
SGI: 
SGRAN_3348(gnl) SGRAN_3512(gnl2)
SPHL: 
LPB140_02625 LPB140_03445
SPHQ: 
BWQ93_07075 BWQ93_12405
STAX: 
MC45_02165
SPHI: 
TS85_00395 TS85_14090
SMY: 
BJP26_05195
SPAN: 
AWL63_01795 AWL63_22830
SPLM: 
BXU08_10835
SPLK: 
AV944_06325
SJP: 
SJA_C2-01000
SCH: 
Sphch_3563 Sphch_4060
SSY: 
SLG_04800
SYB: 
TZ53_07570 TZ53_09745 TZ53_17070 TZ53_18020
SBD: 
ATN00_09950
SPHB: 
EP837_00327 EP837_03538 EP837_03856
SINB: 
SIDU_17630
SPHG: 
AZE99_13135
SFLA: 
SPHFLASMR4Y_03063(gnl)
BLAS: 
BSY18_1270
CMAN: 
A9D14_07935
GOX: 
GOX1375 GOX1381
GOH: 
B932_1525 B932_1550
GOY: 
GLS_c15060 GLS_c15110
ACR: 
Acry_2591 Acry_2596
AMV: 
ACMV_29160 ACMV_29210
GXY: 
GLX_16340
GXL: 
H845_172
KNA: 
B0W47_10430
KEU: 
S101446_02159
APT: 
APA01_06170
APW: 
APA42C_06170
APF: 
APA03_06170
APU: 
APA07_06170
APG: 
APA12_06170
APQ: 
APA22_06170
APX: 
APA26_06170
APZ: 
APA32_06170
APK: 
APA386B_2110
ASZ: 
ASN_2801
ASV: 
WG31_03605
AACE: 
A0U92_16485
APER: 
A0U91_05290
ABG: 
Asbog_00140 Asbog_01831
KBA: 
A0U89_03990 A0U89_08655 A0U89_13560
RGI: 
RGI145_02370 RGI145_06035
NCH: 
A0U93_07365 A0U93_13935
RCE: 
RC1_3591(gnl)
AZL: 
AZL_a09340
TMO: 
TMO_2465
ELM: 
ELI_2936
MSM: 
MSMEG_1274
MSG: 
MSMEI_1237
MSB: 
LJ00_06345
MSN: 
LI99_06345
MSH: 
LI98_06345
MSA: 
Mycsm_01793
MRH: 
MycrhN_0105
MYV: 
G155_15445
MYE: 
AB431_25670
NBR: 
O3I_029330
ROP: 
ROP_31330
ROA: 
Pd630_LPD07055
RPY: 
Y013_23805
GOR: 
KTR9_4361
SCO: 
SCO0524(SCF11.04)
SBH: 
SBI_08977
SVE: 
SVEN_1977
SDV: 
BN159_0814
SLV: 
SLIV_35325
SVT: 
SVTN_35080
SCW: 
TU94_11935
STRM: 
M444_03510
SAMB: 
SAM23877_7015
SPRI: 
SPRI_6246
SCX: 
AS200_17275
SLE: 
sle_45020(sle_45020)
STSI: 
A4E84_17380
SLS: 
SLINC_5802
MTS: 
MTES_3137
MIH: 
BJP65_15630
RTX: 
TI83_01120
RTC: 
APU90_05360
RTN: 
A6122_2724
CUM: 
NI26_01290
CUB: 
BJK06_06810
FRP: 
AX769_20225
ARR: 
ARUE_c05350(gnl)
ARZ: 
AUT26_02580
AAU: 
AAur_0566(gnl)
APN: 
Asphe3_17430
PSUL: 
AU252_01010
BCV: 
Bcav_0231
BRX: 
BH708_04865
DVA: 
DAD186_07530
LMOI: 
VV02_03525
MPH: 
MLP_33370(gnl)
KFL: 
Kfla_1402
SRO: 
Sros_9336
NOA: 
BKM31_46250
FRI: 
FraEuI1c_1591
KRA: 
Krad_1491
SEN: 
SACE_3449 SACE_3789(gnl)
AMD: 
AMED_1802 AMED_3911
AMN: 
RAM_09145 RAM_19920
AMM: 
AMES_1789 AMES_3865
AMZ: 
B737_1790 B737_3865
AOI: 
AORI_5675
AJA: 
AJAP_11105
ALU: 
BB31_32420
PDX: 
Psed_2683 Psed_2686
PSEA: 
WY02_11340
PSEE: 
FRP1_02910
PSEQ: 
AD006_10520 AD006_19385
PECQ: 
AD017_18350 AD017_27225
PHH: 
AFB00_08735 AFB00_24645
KPHY: 
AOZ06_30795
LED: 
BBK82_06640
STP: 
Strop_0658
SAQ: 
Sare_0633
ACTN: 
L083_3178
SNA: 
Snas_4631
CWO: 
Cwoe_2741
AYM: 
YM304_16460
ABAI: 
IMCC26256_11738
SYG: 
sync_0856 sync_1920
SYR: 
SynRCC307_1922
SYX: 
SynWH7803_0722
CYI: 
CBM981_1651
LBO: 
LBWT_22190
GLP: 
Glo7428_0088
CYJ: 
Cyan7822_6104
MIC: 
Mic7113_0062
ONI: 
Osc7112_1292 Osc7112_1491
MPRO: 
BJP34_11355
CEP: 
Cri9333_4873
NPU: 
Npun_F1780 Npun_R3108 Npun_R6059
CALH: 
IJ00_03280
RIV: 
Riv7116_3288
NCN: 
BZZ01_06710
CTHE: 
Chro_1269 Chro_2173
SCS: 
Sta7437_1489
RRS: 
RoseRS_2498
RCA: 
Rcas_2848
CAP: 
CLDAP_05480
DRA: 
DR_0277
DDR: 
Deide_21410
DPT: 
Deipr_1757
DGO: 
DGo_CA0198
DCH: 
SY84_10460
DAB: 
AUC44_14435
CCZ: 
CCALI_00358
FGI: 
OP10G_0808
TTR: 
Tter_2396
PUV: 
PUV_21480
OTE: 
Oter_4181
OBG: 
Verru16b_01578(gnl)
RBA: 
RB1022 RB12740(gnl) RB3234 RB5577(gnl)
PSL: 
Psta_1780 Psta_4311
PIR: 
VN12_03780(gnl_1) VN12_17095(gnl_2) VN12_22385(gnl_4)
PLM: 
Plim_3928
PBS: 
Plabr_0073 Plabr_0477 Plabr_2378
PLS: 
VT03_04095(gnl_1) VT03_12020(gnl_2) VT03_27270(gnl_3)
PLH: 
VT85_14620(gnl_1) VT85_19970(gnl_2) VT85_23330(gnl_3)
FMR: 
Fuma_00039(gnl_1) Fuma_05445(gnl_3) Fuma_06428(gnl_4)
GES: 
VT84_16115(gnl_2) VT84_28840(gnl_4)
IPA: 
Isop_0676
SACI: 
Sinac_4853 Sinac_5868 Sinac_7120 Sinac_7488
PBOR: 
BSF38_01626(gnl_1) BSF38_03622(gnl_2) BSF38_04912(gnl_3)
PHM: 
PSMK_09330 PSMK_30810
PBU: 
L21SP3_01782(bsaA)
ABA: 
Acid345_0646
ACA: 
ACP_0195(gnl)
TRS: 
Terro_1768
SUS: 
Acid_2801 Acid_4513 Acid_7716
ABAC: 
LuPra_01782(gnl)
GBA: 
J421_1876 J421_4303 J421_5396
PBT: 
ING2E5B_1862
PMUC: 
ING2E5A_0045(gnl)
PSAC: 
PSM36_3199
ASX: 
CDL62_13230
RBAR: 
AWN76_008440 AWN76_009770
CPI: 
Cpin_6025
NKO: 
Niako_0685 Niako_3781
NSO: 
NIASO_04255 NIASO_06245
NIA: 
A8C56_15040
FLA: 
SY85_09215
ARB: 
A9P82_12860
HHY: 
Halhy_0725 Halhy_0726 Halhy_1292
PHE: 
Phep_3570
PEP: 
AQ505_15275
PCM: 
AY601_1232
PSTY: 
BFS30_17965
PSN: 
Pedsa_3386
SHG: 
Sph21_1253 Sph21_4037
SHT: 
KO02_18625
SPHN: 
BV902_10610 BV902_16770
MUP: 
A0256_19130
CMR: 
Cycma_1154 Cycma_2443 Cycma_3932 Cycma_4038
CAMU: 
CA2015_1062 CA2015_2388 CA2015_3883 CA2015_3990
BBD: 
Belba_2682
EVI: 
Echvi_0323 Echvi_3767
ALM: 
AO498_10905 AO498_15110
CHU: 
CHU_3561(pgl)
DFE: 
Dfer_2426 Dfer_4750
SLI: 
Slin_0076 Slin_2519 Slin_3203
SRD: 
SD10_17225 SD10_20445
SMON: 
AWR27_00570 AWR27_21810
LBY: 
Lbys_1448
RSI: 
Runsl_3279 Runsl_3865 Runsl_5683
EOL: 
Emtol_2040 Emtol_3340
FAE: 
FAES_0278 FAES_3063
FIB: 
A6C57_17815 A6C57_25615
HSW: 
Hsw_0148 Hsw_1313
HYP: 
A0257_10420
RTI: 
DC20_11865
MTT: 
Ftrac_2514
FBT: 
D770_08515
GFL: 
GRFL_2925
FJG: 
BB050_03191(gnl)
RBI: 
RB2501_11522 RB2501_12567
ZPR: 
ZPR_2466
FBC: 
FB2170_00750 FB2170_02055
MARM: 
YQ22_13570
MART: 
BTR34_13510
CAO: 
Celal_0292 Celal_2505
CBAL: 
M667_09820
CBAT: 
M666_09810
ZGA: 
ZOBELLIA_2920(gnlA) ZOBELLIA_587
MRS: 
Murru_3161
PTQ: 
P700755_000276
MYR: 
MYRA21_0191(gnl)
MPW: 
MPR_2731
MOD: 
AS202_00270
MYZ: 
BK054_00500
CHZ: 
CHSO_1625(gnl)
CGN: 
OK18_14350
CIH: 
ATE47_04510
CHH: 
A0O34_02110
CIO: 
CEQ15_01855
CHRY: 
CEY12_21440
LUL: 
LPB138_02570
SALT: 
AO058_07060
MRO: 
MROS_2083
CABY: 
Cabys_4176
NMV: 
NITMOv2_4019 NITMOv2_4020
HGI: 
ABY42_15860
 » show all
Taxonomy
Reference
1  [PMID:14353869]
  Authors
BRODIE AF, LIPMANN F.
  Title
Identification of a gluconolactonase.
  Journal
J. Biol. Chem. 212 (1955) 677-85.
Reference
2
  Authors
Bublitz, C. and Lehninger, A.L.
  Title
The role of aldonolactonase in the conversion of L-gulonate to L-ascorbate.
  Journal
Biochim. Biophys. Acta 47 (1961) 288-297.
Reference
3
  Authors
Suzuki, K., Kawada, M. and Shimazono, N.
  Title
Soluble lactonase. Identity of lactonase I and aldonolactonase with gluconolactonase.
  Journal
J. Biochem. (Tokyo) 49 (1961) 448-449.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9012-73-1
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