Entry |
|
Name |
gluconolactonase;
lactonase;
aldonolactonase;
glucono-delta-lactonase;
gulonolactonase
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Class |
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
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Sysname |
D-glucono-1,5-lactone lactonohydrolase
|
Reaction(IUBMB) |
D-glucono-1,5-lactone + H2O = D-gluconate [RN: R01519]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Acts on a wide range of hexose-1,5-lactones. The hydrolysis of L-gulono-1,5-lactone was previously listed separately.
|
History |
EC 3.1.1.17 created 1961 (EC 3.1.1.18 created 1961, incorporated 1982)
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Pathway |
ec00053 | Ascorbate and aldarate metabolism |
ec01110 | Biosynthesis of secondary metabolites |
ec01120 | Microbial metabolism in diverse environments |
ec01130 | Biosynthesis of antibiotics |
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Orthology |
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Genes |
» show all
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Reference |
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Authors |
BRODIE AF, LIPMANN F. |
Title |
Identification of a gluconolactonase. |
Journal |
J. Biol. Chem. 212 (1955) 677-85. |
Reference |
2 |
Authors |
Bublitz, C. and Lehninger, A.L. |
Title |
The role of aldonolactonase in the conversion of L-gulonate to L-ascorbate. |
Journal |
Biochim. Biophys. Acta 47 (1961) 288-297. |
Reference |
3 |
Authors |
Suzuki, K., Kawada, M. and Shimazono, N. |
Title |
Soluble lactonase. Identity of lactonase I and aldonolactonase with gluconolactonase. |
Journal |
J. Biochem. (Tokyo) 49 (1961) 448-449. |
Other DBs |
ExplorEnz - The Enzyme Database: | 3.1.1.17 |
ExPASy - ENZYME nomenclature database: | 3.1.1.17 |
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