KEGG   ENZYME: 3.1.2.1Help
Entry
EC 3.1.2.1                  Enzyme                                 
Name
acetyl-CoA hydrolase;
acetyl-CoA deacylase;
acetyl-CoA acylase;
acetyl coenzyme A hydrolase;
acetyl coenzyme A deacylase;
acetyl coenzyme A acylase;
acetyl-CoA thiol esterase
Class
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
BRITE hierarchy
Sysname
acetyl-CoA hydrolase
Reaction(IUBMB)
acetyl-CoA + H2O = CoA + acetate [RN:R00227]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
H2O [CPD:C00001]
Product
CoA [CPD:C00010];
acetate [CPD:C00033]
Pathway
Pyruvate metabolism
Orthology
K01067  
acetyl-CoA hydrolase
Genes
HSA: 
134526(ACOT12)
PTR: 
461769(ACOT12)
PPS: 
100970341(ACOT12)
GGO: 
101152146(ACOT12)
PON: 
100438971(ACOT12)
MCC: 
711665(ACOT12)
MMU: 
74156(Acot12)
RNO: 
170570(Acot12)
CFA: 
488925(ACOT12)
AML: 
FCA: 
101091423(ACOT12)
BTA: 
525155(ACOT12)
SSC: 
100738062(ACOT12)
ECB: 
100073251(ACOT12)
MDO: 
100015770(ACOT12)
SHR: 
100919572(ACOT12)
OAA: 
100081254(ACOT12)
GGA: 
431627(ACOT12)
TGU: 
100219385(ACOT12)
ACS: 
100554997
XLA: 
444535(acot12)
XTR: 
100170471(acot12)
DRE: 
100536873
SCE: 
YBL015W(ACH1)
AGO: 
AGOS_AFR020W
KLA: 
KLLA0E10561g
LTH: 
KLTH0H08338g
PPA: 
PAS_chr3_0253
VPO: 
Kpol_1002p112
ZRO: 
ZYRO0C13134g
CGR: 
CAGL0J04268g
DHA: 
DEHA2F18744g
PIC: 
PICST_78208(ACH1)
PGU: 
PGUG_02595
LEL: 
LELG_03976
CAL: 
CaO19.10681(ACH1) CaO19.3171(ACH1)
CTP: 
CTRG_05320
CDU: 
CD36_51850
YLI: 
YALI0E30965g
CLU: 
CLUG_02878
NCR: 
NCU09770
PAN: 
PODANSg552
MGR: 
MGG_06609
FGR: 
FG08266.1
SSL: 
SS1G_03975
BFU: 
BC1G_14217
ANI: 
AN1547.2
NFI: 
NFIA_098300
AFM: 
AFUA_8G05580
AOR: 
AOR_1_1028174(AO090005000588)
ANG: 
ANI_1_938144(An16g07110)
AFV: 
AFLA_078380
ACT: 
ACLA_058990
PCS: 
Pc12g03130
CIM: 
CIMG_08724
CPW: 
CPC735_063030
URE: 
UREG_02698
PNO: 
SNOG_05874
SPO: 
SPAC1952.09c
LBC: 
LACBIDRAFT_252427
CCI: 
CC1G_08888
SCM: 
SCHCODRAFT_69884
NGR: 
NAEGRDRAFT_38428
DDI: 
DDB_G0287519
TVA: 
TVAG_395550
XCA: 
xccb100_0566(ach)
SMT: 
Smal_0350
FAU: 
Fraau_1571
PAG: 
PLES_58401
PDK: 
PADK2_28970
PPF: 
Pput_0172
PPG: 
PputGB1_0170
PPW: 
PputW619_5073
PFL: 
PFL_0112
PFO: 
Pfl01_0111
PFS: 
PFLU0110
PEN: 
PSEEN0113
PBA: 
PSEBR_a151
PCR: 
Pcryo_1227
ABC: 
ACICU_03426
ABN: 
AB57_3679
ABB: 
ABBFA_000284
MCT: 
MCR_0670(ach1)
PHA: 
PSHAa2002(ygfH)
PAT: 
Patl_3791
LHK: 
LHK_02849
PSE: 
NH8B_3318(ach)
RPI: 
Rpic_1335
RPF: 
Rpic12D_1400
REU: 
Reut_A1290
REH: 
H16_A1358(h16_A1358) H16_B1368
RME: 
Rmet_4895(ygfH)
BVI: 
Bcep1808_4692
BUR: 
Bcep18194_A4202 Bcep18194_B1909 Bcep18194_C7279
BCN: 
Bcen_4240
BCH: 
Bcen2424_4126
BCM: 
Bcenmc03_3393
BCJ: 
BCAM1250
BAM: 
Bamb_3540
BAC: 
BamMC406_4021
BMU: 
Bmul_4466
BMJ: 
BMULJ_04044(ach1)
BXE: 
Bxe_B0292 Bxe_B0397 Bxe_B1860
BPH: 
Bphy_5077
BPY: 
Bphyt_4800 Bphyt_5109
BUG: 
BC1001_1331
BGE: 
BC1002_3634
BGF: 
BC1003_2060
BRH: 
RBRH_03454
BAV: 
BAV2501
AXY: 
AXYL_04838
TEQ: 
TEQUI_0450
RFR: 
Rfer_1216
PNA: 
Pnap_0073
AAV: 
Aave_0100
AJS: 
Ajs_0046 Ajs_0123
DIA: 
Dtpsy_0066
AAA: 
Acav_0130
DAC: 
Daci_0085
DEL: 
DelCs14_0084
CTT: 
CtCNB1_0090 CtCNB1_0236
ADN: 
Alide_0079
ADK: 
Alide2_0070
DAR: 
Daro_2807
DSU: 
Dsui_0799
GUR: 
Gura_1337 Gura_4029
GLO: 
Glov_0345 Glov_3013
GEO: 
Geob_0742 Geob_2594
GEM: 
GM21_0485 GM21_0842 GM21_3982
PPD: 
Ppro_0286
BBA: 
Bd1620
DAT: 
HRM2_15970(ach1)
ADE: 
Adeh_1288
ACP: 
A2cp1_2668
AFW: 
Anae109_2477
ANK: 
AnaeK_2572
MXA: 
MXAN_2285
SUR: 
STAUR_1722
SFU: 
Sfum_0388 Sfum_0389
ATU: 
Atu0396
AVI: 
Avi_0516
AGR: 
AGROH133_03637
RLE: 
pRL90030
BME: 
BMEI0928
BMI: 
BMEA_A1099
BMF: 
BAB1_1077
BMB: 
BruAb1_1062
BMC: 
BAbS19_I09990
BMT: 
BSUIS_A1102
BOV: 
BOV_1023
BCS: 
BCAN_A1073
BMR: 
BMI_I1063
OAN: 
Oant_2146
RPA: 
RPA0537
RPB: 
RPB_0503
RPC: 
RPC_0254
RPD: 
RPD_0322
RPE: 
RPE_0804
RPT: 
Rpal_0538
XAU: 
Xaut_1730
AZC: 
AZC_3728
SNO: 
Snov_1616
BID: 
Bind_0767
RVA: 
Rvan_0941
CAK: 
Caul_5056
AEX: 
Astex_0115
RSP: 
RSP_0029
RSH: 
Rsph17029_1658
RSQ: 
Rsph17025_2183
RSK: 
RSKD131_1337
PDE: 
Pden_4309
SJP: 
SJA_C1-05830
ACR: 
Acry_1436
RRU: 
Rru_A1927
RCE: 
RC1_0310
MAG: 
amb1383
AZL: 
AZL_d02810
DIN: 
Selin_0775
CKL: 
CKL_3016(cat1)
CKR: 
CKR_2664
CDL: 
CDR20291_2232(cat1)
AOE: 
Clos_0435
TOC: 
Toce_1836
TTM: 
Tthe_1655
SSG: 
Selsp_0501
RHA: 
RHA1_ro03558 RHA1_ro10175
FAL: 
FRAAL3473
LBI: 
LEPBI_I0851
LBF: 
LBF_0820
ABA: 
Acid345_0950
SUS: 
Acid_6953
PSN: 
Pedsa_1394
SHG: 
Sph21_1710
DFE: 
Dfer_2213
LBY: 
Lbys_1257
WVI: 
Weevi_0491
IPO: 
Ilyop_2731
TAI: 
Taci_0301
TLI: 
Tlie_1893
CCH: 
Cag_0060
CLI: 
Clim_1025
PPH: 
Ppha_2304
RRS: 
RoseRS_0911
DAP: 
Dacet_1280
CNI: 
Calni_0213
FSI: 
Flexsi_1428
MSE: 
Msed_1217
 » show all
Taxonomy
Reference
1  [PMID:12999747]
  Authors
GERGELY J, HELE P, RAMAKRISHNAN CV.
  Title
Succinyl and acetyl coenzyme a deacylases.
  Journal
J. Biol. Chem. 198 (1952) 324-34.
  Organism
Sus scofa [GN:ssc]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9027-54-7
DBGET integrated database retrieval system