| Entry |
|
|---|
| Name |
fructose-2,6-bisphosphate 2-phosphatase;
fructose-2,6-bisphosphatase;
D-fructose-2,6-bisphosphate 2-phosphohydrolase |
|---|
| Class |
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
 |
|---|
| Sysname |
beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase |
|---|
| Reaction(IUBMB) |
beta-D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate +
phosphate [RN:R00763] |
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| Reaction(KEGG) |
R00763 > R02731
 |
|---|
| Substrate |
beta-D-fructose 2,6-bisphosphate [CPD:C00665];
H2O [CPD:C00001] |
|---|
| Product |
D-fructose 6-phosphate [CPD:C00085];
phosphate [CPD:C00009] |
|---|
| Comment |
The enzyme copurifies with EC 2.7.1.105 6-phosphofructo-2-kinase.
(cf. EC 3.1.3.54 fructose-2,6-bisphosphate 6-phosphatase). |
|---|
| Pathway |
ec00051 Fructose and mannose metabolism |
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| Orthology |
K01103 fructose-2,6-bisphosphatase |
|---|
| Genes |
HSA: 5207(PFKFB1) 5208(PFKFB2) 5209(PFKFB3) 5210(PFKFB4)
PTR: 738397(PFKFB3)
MCC: 709854 713062(PFKFB3)
MMU: 170768(Pfkfb3) 18639(Pfkfb1) 18640(Pfkfb2) 270198(Pfkfb4)
RNO: 117276(Pfkfb3) 24638(Pfkfb1) 24640(Pfkfb2) 54283(Pfkfb4)
CFA: 480011(PFKFB2) 484777(PFKFB4) 487139(PFKFB3) 491903(PFKFB1)
BTA: 282304(PFKFB1) 287019(PFKFB2) 407183(PFKFB3) 534928(PFKFB4)
SSC: 100158056 100233197(PFKFB1)
ECB: 100051146 100053840(PFKFB4) 100062514(PFKFB1) 100070251
MDO: 100010280 100014887 100020159 100023544
OAA: 100078789 100085808
GGA: 415906(PFKFB4) 418247(PFKFB3) 419850(PFKFB2)
TGU: 100220196 100227828 100232575
XLA: 432000(pfkfb4) 495408(pfkfb1)
XTR: 100170160(pfkfb2) 407880(pfkfb4)
DRE: 386663(pfkfb4l) 393983(pfkfb2) 554477(pfkfb3) 555486
556190(pfkfb4) 564852
BFO: BRAFLDRAFT_277775
SPU: 579456 759612
DME: Dmel_CG3400(Pfrx)
DPO: Dpse_GA17426
DAN: Dana_GF20194
DER: Dere_GG19228
DSE: Dsec_GM22962
DWI: Dwil_GK25408
DYA: Dyak_GE15846
DGR: Dgri_GH17653
DMO: Dmoj_GI16091
DVI: Dvir_GJ15740
AGA: AgaP_AGAP012010
AAG: AaeL_AAEL013132
CQU: CpipJ_CPIJ004664
AME: 409574(Pfrx)
NVI: 100121543(NV15615)
TCA: 657985
API: 100162819(ACYPI003942)
PHU: Phum_PHUM258260
ISC: IscW_ISCW008488
CEL: K02B2.1(6-phosphofructo-2-kinase)
Y110A7A.6(phosphofructokinase)
CBR: CBG09461 CBG10830
SMM: Smp_015710
NVE: NEMVE_v1g234745
HMG: 100203886
TAD: TRIADDRAFT_24566 TRIADDRAFT_37504
ATH: AT1G07110(F2KP)
POP: POPTR_815458 POPTR_821351
RCU: RCOM_1668120
VVI: 100244966
OSA: 4332523(Os03g0294200) 4337906(Os05g0164100)
SBI: SORBI_09g004780
ZMA: 541911
PPP: PHYPADRAFT_146321 PHYPADRAFT_194396 PHYPADRAFT_61651
CRE: CHLREDRAFT_121054
OLU: OSTLU_40330
CME: CMN085C
SCE: YJL155C(FBP26)
AGO: AGOS_AEL106W
KLA: KLLA0B07513g
LTH: KLTH0F05126g
DHA: DEHA2A11374g
PIC: PICST_68318(FBP26)
PPA: PAS_chr2-1_0110
PGU: PGUG_01944
VPO: Kpol_2001p19
LEL: LELG_03110
ZRO: ZYRO0G18216g
CTP: CTRG_03101
CDU: CD36_34140
CGR: CAGL0I06094g
YLI: YALI0E17633g
CLU: CLUG_02842
SPO: SPAC144.17c SPAC732.02c SPAPB17E12.14c
NCR: NCU09347
PAN: PODANSg501
MGR: MGG_06524(MG06524.4)
FGR: FG04343.1
ANI: AN6720.2
AFM: AFUA_7G05800
AOR: AO090005000443 AO090005000444
ANG: An07g02100
AFV: AFLA_076770
ACT: ACLA_007490
PCS: Pc20g01550
NFI: NFIA_027040
CIM: CIMG_05445
URE: UREG_06273
SSL: SS1G_10745
BFU: BC1G_15078
PNO: SNOG_15665
CNE: CNI03630
CNB: CNBH3460
PPL: POSPLDRAFT_26627
LBC: LACBIDRAFT_254988
MPR: MPER_06685
UMA: UM02633.1
MGL: MGL_3954
MBR: MONBRDRAFT_27797
NGR: NAEGRDRAFT_79111
DDI: DDB_G0276253
PTM: GSPATT00007537001 GSPATT00020537001 GSPATT00032010001
TBR: Tb10.70.2700 Tb927.7.1610 Tb927.8.1020
LMA: LmjF26.0310
LIF: LinJ26.0300
LBZ: LbrM26_V2.0340
PTI: PHATRDRAFT_17495(PF2K1)
TPS: THAPSDRAFT_14563(PF2K1)
REH: H16_B0760
HAR: HEAR1955
DVU: DVU3147
DVL: Dvul_0238
DVM: DvMF_1696
DDE: Dde_0511
DDS: Ddes_0350
DMA: DMR_34760(pfkfb)
LIP: LI0094(pfk)
DRT: Dret_0204
SCL: sce0036(fbp1)
GBE: GbCGDNIH1_2335
DAP: Dacet_1617
 |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:6282585]
van Schaftingen E, Davies DR, Hers HG.
Fructose-2,6-bisphosphatase from rat liver.
Eur. J. Biochem. 124 (1982) 143-9.
Rattus norvegicus [GN:rno] |
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| Other DBs |
ExplorEnz - The Enzyme Database: 3.1.3.46
IUBMB Enzyme Nomenclature: 3.1.3.46
ExPASy - ENZYME nomenclature database: 3.1.3.46
BRENDA, the Enzyme Database: 3.1.3.46
CAS: 81611-75-8 |
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