KEGG   ENZYME: 3.2.1.132Help
Entry
EC 3.2.1.132                Enzyme                                 
Name
chitosanase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
chitosan N-acetylglucosaminohydrolase
Reaction(IUBMB)
Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan
Reaction(KEGG)
(other) R02833 R06175(G)
Show
Comment
A whole spectrum of chitosanases are now known (for more details, see http://pages.usherbrooke.ca/rbrzezinski/). They can hydrolyse various types of links in chitosan. The only constant property is the endohydrolysis of GlcN-GlcN links, which is common to all known chitosanases. One known chitosanase is limited to this link recognition [4], while the majority can also recognize GlcN-GlcNAc links or GlcNAc-GlcN links but not both. They also do not recognize GlcNAc-GlcNAc links in partly acetylated chitosan.
Pathway
Amino sugar and nucleotide sugar metabolism
Biosynthesis of secondary metabolites
Orthology
K01233  
chitosanase
Genes
NFI: 
AFM: 
ACT: 
PCS: 
CJA: 
CVI: 
BRH: 
BGD: 
NII: 
DAR: 
TMZ: 
Tmz1t_3574
MSD: 
MYSTI_01268
CCX: 
COCOR_06517
PLA: 
Plav_0939
BSU: 
BSU26890(csn)
BSR: 
I33_2730
BSL: 
A7A1_0329
BSH: 
BSU6051_26890(csn)
BSY: 
I653_12750
BST: 
GYO_2921
BSO: 
BSNT_03901(csn)
BSN: 
BSn5_04145
BSQ: 
B657_26890(csn)
BSUB: 
BEST7613_4188(csn)
BSX: 
C663_2522(csn)
BAO: 
BAMF_3066(csn)
BAY: 
RBAM_029740(csn)
BAQ: 
BACAU_3000(csn)
BYA: 
BANAU_3164(csn)
BAMP: 
B938_15235
BAML: 
BAM5036_2888(csn)
BAZ: 
BAMTA208_16520(csn)
BQL: 
LL3_03344(csn)
BXH: 
BAXH7_03372(csn)
BQY: 
MUS_3567(csn)
BAMI: 
KSO_004285
BAE: 
BATR1942_06760
BJS: 
MY9_2670
PPM: 
PPSC2_c3877
PCE: 
PECL_1823(csn)
CBE: 
Cbei_0949
CSH: 
Closa_0438
SCO: 
SCO0677(csn)
SMA: 
SAV_6191(csn2)
SSX: 
SACTE_5457 SACTE_5886
SVL: 
Strvi_2888
SCT: 
SCAT_5429(csn)
SCY: 
SCATT_54280
SFA: 
Sfla_1048
SBH: 
SBI_02563
SHY: 
SHJG_1996
SHO: 
SHJGH_1761
SDV: 
BN159_0876(csn1) BN159_6425(csn3)
SALB: 
XNR_0630 XNR_4855
STRP: 
F750_5797
KSK: 
KSE_15150(csn1) KSE_40860(csn2) KSE_40930(csn3)
RSA: 
RSal33209_3139
SRO: 
Sros_2053
AMD: 
AMED_6991
AMN: 
RAM_35860
AMM: 
AMES_6884
AMI: 
Amir_4331
AMS: 
AMIS_60150
ASE: 
ACPL_2150(csn)
 » show all
Taxonomy
Reference
1
  Authors
Fenton, D.M. and Eveleigh, D.E.
  Title
Purification and mode of action of a chitosanase from Penicillium islandicum.
  Journal
J. Gen. Microbiol. 126 (1981) 151-165.
Reference
2  [PMID:10521473]
  Authors
Saito J, Kita A, Higuchi Y, Nagata Y, Ando A, Miki K.
  Title
Crystal structure of chitosanase from Bacillus circulans MH-K1 at 1.6-A resolution and its substrate recognition mechanism.
  Journal
J. Biol. Chem. 274 (1999) 30818-25.
  Organism
Bacillus circulans
Reference
3  [PMID:1368330]
  Authors
Izume M, Nagae S, Kawagishi H, Mitsutomi M, Ohtakara A.
  Title
Action pattern of Bacillus sp. no. 7-M chitosanase on partially N-acetylated chitosan.
  Journal
Biosci. Biotechnol. Biochem. 56 (1992) 448-53.
  Organism
Bacillus sp.
Reference
4  [PMID:8564542]
  Authors
Marcotte EM, Monzingo AF, Ernst SR, Brzezinski R, Robertus JD.
  Title
X-ray structure of an anti-fungal chitosanase from streptomyces N174.
  Journal
Nat. Struct. Biol. 3 (1996) 155-62.
  Organism
Streptomyces sp.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
51570-20-8
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