KEGG   ENZYME: 3.2.1.132Help
Entry
EC 3.2.1.132                Enzyme                                 

Name
chitosanase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
chitosan N-acetylglucosaminohydrolase
Reaction(IUBMB)
Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan
Reaction(KEGG)
(other) R02833 R06175(G)
Show
Comment
A whole spectrum of chitosanases are now known (for more details, see {http://rbrzezinski.recherche.usherbrooke.ca/::http://rbrzezinski.recherche.usherbrooke.ca/}). They can hydrolyse various types of links in chitosan. The only constant property is the endohydrolysis of GlcN-GlcN links, which is common to all known chitosanases. One known chitosanase is limited to this link recognition [4], while the majority can also recognize GlcN-GlcNAc links or GlcNAc-GlcN links but not both. They also do not recognize GlcNAc-GlcNAc links in partly acetylated chitosan.
History
EC 3.2.1.132 created 1990, modified 2004
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec01100  Metabolic pathways
Orthology
K01233  chitosanase
Genes
AFM: AFUA_3G14980 AFUA_4G01290 AFUA_6G00500 AFUA_8G00930
AFV: AFLA_089380
ACT: ACLA_016840
NFI: NFIA_062130
PCS: Pc12g07820
PDP: PDIP_35480
KMI: VW41_11695
CNT: JT31_00610
CEM: LH23_16605
CEN: LH86_15590
CJA: CJA_3747
CVI: CV_3931
BGO: BM43_4589(csn)
JAG: GJA_1109(csn) GJA_1110(csn) GJA_1111(csn) GJA_1112(csn) GJA_1802(csn) GJA_1803(csn)
CARE: LT85_2580
CPRA: CPter91_3397(csn)
DAR: Daro_2852
PLA: Plav_0939
BSU: BSU26890(csn)
BSR: I33_2730
BSL: A7A1_0329
BSH: BSU6051_26890(csn)
BSUT: BSUB_02870(csn)
BSUL: BSUA_02870(csn)
BSUS: Q433_14455
BST: GYO_2921
BSO: BSNT_09076(csn)
BSQ: B657_26890(csn)
BSX: C663_2522(csn)
BAY: RBAM_029740(csn)
BAQ: BACAU_3000(csn)
BYA: BANAU_3164(csn)
BAMP: B938_15235
BAML: BAM5036_2888(csn)
BAMA: RBAU_3106(csn)
BAMN: BASU_2894(csn)
BAMB: BAPNAU_3155(csn)
BAMT: AJ82_16845
BAMY: V529_32340(csn)
BMP: NG74_03126(csn)
BAO: BAMF_3066(csn)
BAZ: BAMTA208_16520(csn)
BQL: LL3_03344(csn)
BXH: BAXH7_03372(csn)
BQY: MUS_3567(csn)
BAMI: KSO_004285
BAMC: U471_30820
BAMF: U722_16000
BATR: TD68_06185
BJS: MY9_2670
BACP: SB24_13865
BACB: OY17_18210
BACY: QF06_11630
BACL: BS34A_29350(csn)
BALM: BsLM_2641
SCAP: AYP1020_2099(csn)
SSCH: LH95_00710
SSCZ: RN70_00920
PPM: PPSC2_18125(csn)
PPO: PPM_3647(csn)
PPOL: X809_34215
PPOY: RE92_19075
PCE: PECL_1823(csn)
CBE: Cbei_0949
CBZ: Cbs_0949
CBEI: LF65_01008
SCO: SCO0677(csn) SCO2024(SC3A3.02)
SMA: SAVERM_6191(csn2)
SCT: SCAT_5429(csn)
SBH: SBI_02563
SHY: SHJG_1996
SDV: BN159_0394 BN159_0876(csn1) BN159_6425(csn3)
SFI: SFUL_6175
SALU: DC74_6404
SALL: SAZ_32170
SLV: SLIV_27590(csn1) SLIV_34555(csn2)
SGU: SGLAU_09170(csn)
SLD: T261_1844
STRM: M444_06945
SRW: TUE45_00747(csn)
SLE: sle_51160(sle_51160)
SMAL: SMALA_6368
SALJ: SMD11_1083(csn)
SLX: SLAV_07155(csn)
KSK: KSE_15150(csn1) KSE_40860(csn2) KSE_40930(csn3)
LMOI: VV02_22645
SRO: Sros_2053
AMD: AMED_6991
AMN: RAM_35860
AMM: AMES_6884
AMZ: B737_6884
AOI: AORI_1736
AJA: AJAP_30805(csn)
AMI: Amir_4331
ASE: ACPL_2150(csn) ACPL_7579(csn2)
ACTN: L083_7237(csn2) L083_7833
 » show all
Taxonomy
Reference
1
  Authors
Fenton, D.M. and Eveleigh, D.E.
  Title
Purification and mode of action of a chitosanase from Penicillium islandicum.
  Journal
J. Gen. Microbiol. 126 (1981) 151-165.
Reference
2  [PMID:10521473]
  Authors
Saito J, Kita A, Higuchi Y, Nagata Y, Ando A, Miki K.
  Title
Crystal structure of chitosanase from Bacillus circulans MH-K1 at 1.6-A resolution and its substrate recognition mechanism.
  Journal
J. Biol. Chem. 274 (1999) 30818-25.
  Sequence
Reference
3  [PMID:1368330]
  Authors
Izume M, Nagae S, Kawagishi H, Mitsutomi M, Ohtakara A.
  Title
Action pattern of Bacillus sp. no. 7-M chitosanase on partially N-acetylated chitosan.
  Journal
Biosci. Biotechnol. Biochem. 56 (1992) 448-53.
Reference
4  [PMID:8564542]
  Authors
Marcotte EM, Monzingo AF, Ernst SR, Brzezinski R, Robertus JD.
  Title
X-ray structure of an anti-fungal chitosanase from streptomyces N174.
  Journal
Nat. Struct. Biol. 3 (1996) 155-62.
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.132
IUBMB Enzyme Nomenclature: 3.2.1.132
ExPASy - ENZYME nomenclature database: 3.2.1.132
BRENDA, the Enzyme Database: 3.2.1.132
CAS: 51570-20-8

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