KEGG   ENZYME: 3.2.1.17Help
Entry
EC 3.2.1.17                 Enzyme                                 
Name lysozyme;
muramidase;
globulin G;
mucopeptide glucohydrolase;
globulin G1;
N,O-diacetylmuramidase;
lysozyme g;
L-7001;
1,4-N-acetylmuramidase;
mucopeptide N-acetylmuramoylhydrolase;
PR1-lysozyme
Class Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl
compounds
BRITE hierarchy
Sysname peptidoglycan N-acetylmuramoylhydrolase
Reaction(IUBMB) Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and
N-acetyl-D-glucosamine residues in a peptidoglycan and between
N-acetyl-D-glucosamine residues in chitodextrins
Comment cf. also EC 3.2.1.14 chitinase.
Orthology K01185  lysozyme
K11331  cation efflux system protein involved in nickel and cobalt
        tolerance
K13381  bifunctional chitinase/lysozyme
K13915  lysozyme C
Genes HSA: 119180(LYZL2) 389852(SPACA5) 4069(LYZ) 57151(LYZL6)
     729201(SPACA5B) 84569(LYZL1)
PTR: 450190(LYZ) 465613(SPACA5B) 468388(LYZL6) 736064(LYZL2)
MCC: 693706 708435(SPACA5) 716662 718361(LYZ)
MMU: 17105(Lyz2) 17110(Lyz1) 278203(Spaca5) 67328(Lyzl1)
     69444(Lyzl6)
RNO: 25211(Lyz2) 287751(Lyzl6) 314431(Spaca5) 364745(Lyzl1)
     688047(Lyc2)
CFA: 474442(LYZ) 480492(LYZL6) 480901(SPACA5) 487083(LYZL1)
BTA: 280849(LYZ2) 281287(LYZ1) 281289(LYZ3) 493637(LYSB)
     512087(LYZL1) 517880(SPACA5) 540048(LYZL6) 777776(LYZ) 781146
     781349(LYZ1)
SSC: 100157211(LYZ) 100415934(SPACA5)
ECB: 100052143 100055156 100061578 100063794
MDO: 100011114 100013718 100015220
OAA: 100076093 100079369
GGA: 396218(LYZ)
XTR: 448362 496769(spaca5)
DRE: 677744(lyz)
BFO: BRAFLDRAFT_67146
DME: Dmel_CG11159 Dmel_CG1165(LysS) Dmel_CG1179(LysB)
     Dmel_CG1180(LysE) Dmel_CG16756 Dmel_CG16799 Dmel_CG30062
     Dmel_CG7798 Dmel_CG8492 Dmel_CG9111(LysC) Dmel_CG9116(LysP)
     Dmel_CG9118(LysD) Dmel_CG9120(LysX)
DPO: Dpse_GA11118 Dpse_GA20595
DAN: Dana_GF10076 Dana_GF12660
DER: Dere_GG14615 Dere_GG22291
DPE: Dper_GL16156
DSE: Dsec_GM20080
DSI: Dsim_GD25558
DWI: Dwil_GK12043 Dwil_GK12154
DYA: Dyak_GE14087
DGR: Dgri_GH21060
DMO: Dmoj_GI18662
DVI: Dvir_GJ21678
AGA: AgaP_AGAP007344 AgaP_AGAP007347
AAG: AaeL_AAEL003723 AaeL_AAEL005988
CQU: CpipJ_CPIJ005450
TCA: 658610(Lyz)
PHU: Phum_PHUM563940
ISC: IscW_ISCW001645
MGR: MGG_10631(MG10631.4)
TET: TTHERM_00024350 TTHERM_00024410 TTHERM_00083410 TTHERM_00083420
     TTHERM_00666790 TTHERM_01243480 TTHERM_01250150
ECO: b0555(arrD) b1554(arrQ) b3338(chiA)
ECJ: JW0544(ybcS) JW1546(ydfQ) JW3300(chiA)
ECD: ECDH10B_0512(ybcS) ECDH10B_1339(R) ECDH10B_1686(ydfQ)
EBW: BWG_0427(arrD) BWG_3029(chiA)
ECE: Z0960
ECS: ECs0819 ECs2741
ECF: ECH74115_0892 ECH74115_2785 ECH74115_2900
EOJ: ECO26_0595
EOI: ECO111_2964
EOH: ECO103_0530
ECG: E2348C_0690 E2348C_1250 E2348C_1412
EOK: G2583_0688(ybcS) G2583_0970(ybcS)
ECC: c0957 c1436 c1562(ybcS) c3180 c4109(chiA)
ECP: ECP_1160 ECP_3428
ECI: UTI89_C1303(ybcS1) UTI89_C1490 UTI89_C2660 UTI89_C3793(yheB)
     UTI89_C5112(ybcS2)
ECV: APECO1_1029 APECO1_2033(ydfQ) APECO1_242(ybcS2)
     APECO1_3115(yheB) APECO1_392 APECO1_4196 APECO1_514
ECX: EcHS_A0931 EcHS_A1644 EcHS_A3533(chiA)
ECW: EcE24377A_0827
ECM: EcSMS35_1183
ECY: ECSE_0589
ECR: ECIAI1_0777(ybcS) ECIAI1_1597(ydfQ)
ECQ: ECED1_3082(R) ECED1_3998(chiA)
ECK: EC55989_0784(ybcS) EC55989_1384(ydfQ) EC55989_2620(ybcS)
ECT: ECIAI39_1503(ydfQ) ECIAI39_1808(R) ECIAI39_4875(ybcS)
EUM: ECUMN_1335(ydfQ) ECUMN_1411(ybcS) ECUMN_1841(ydfQ)
ECZ: ECS88_1185(ybcS) ECS88_2828(R) ECS88_3726(chiA)
     ECS88_5020(ydfQ)
ECL: EcolC_0375 EcolC_2083
EBR: ECB_00507(ybcS) ECB_03189(chiA)
EBD: ECBD_3100
EFE: EFER_2052(ybcS) EFER_4440(ydfQ)
STY: STY2044 STY3682(nucD) STY4620(nucD2)
STT: t3424(nucD) t4314(nucD)
STM: STM1028 STM2715.S
SPT: SPA2397(gp19) SPA2575(nucD)
SEI: SPC_1031 SPC_2723
SEC: SC0986(lycV) SC2614(lycV)
SEH: SeHA_C0394 SeHA_C1136
SEE: SNSL254_A1065 SNSL254_A1150
SEW: SeSA_A0629
SEA: SeAg_B2861
SED: SeD_A1402 SeD_A3043
SEG: SG1208
SET: SEN1145
SES: SARI_01479 SARI_02656
YPE: YPO2098
YPN: YPN_1570
YPP: YPDSF_1029
YPG: YpAngola_A2180
YPS: YPTB1755 YPTB1805
YEN: YE1840 YE2334
SFL: SF0691
SFX: S0733 S0944
SFV: SFV_0212 SFV_0279 SFV_0726(ybcS) SFV_2706
SSN: SSON_0733 SSON_2437 SSON_2783(ybcS)
SBO: SBO_0765 SBO_1924
SBC: SbBS512_E0944 SbBS512_E1270 SbBS512_E1450
SDY: SDY_1394
PCT: PC1_0580 PC1_2648
ETA: ETA_05770
PLU: plu3414
PAY: PAU_03122(gene0068) PAU_03330
SGL: SG0728 SG0939 SG1161 SG1387 SG1559 SG1671 SG1681
ENT: Ent638_0795 Ent638_2248 Ent638_2609 Ent638_3494
ESA: ESA_01625 ESA_02747
CTU: Ctu_05120 Ctu_34260(arrD)
KPE: KPK_3373 KPK_4149
KVA: Kvar_1790
CKO: CKO_01876
SPE: Spro_0871 Spro_2036
PMR: PMI0491
HDE: HDEF_0409 HDEF_1459 HDEF_1675(F)
XBO: XBJ1_1202 XBJ1_1387(ydfQ)
XNE: XNC1_2340
PAM: PANA_3151(nucD2)
HIT: NTHI1880
HSO: HS_1388
APL: APL_0505
AAP: NT05HA_0490
XFA: XF0513 XF1564 XF2314
XFT: PD0996(lycV) PD1113
XFM: Xfasm12_0912
XFN: XfasM23_1053
VCO: VC0395_1046
VHA: VIBHAR_01975
PAP: PSPA7_0693
PPG: PputGB1_3388
PAR: Psyc_1032
ABM: ABSDF0706 ABSDF1811
ABN: AB57_2671
SON: SO_0659
SDN: Sden_3256
SBL: Sbal_1293 Sbal_3605
SDE: Sde_2761
CBU: CBU_1031
CBG: CbuG_0979
MCA: MCA2680
CSA: Csal_1392
AHA: AHA_2050
CVI: CV_0727 CV_2611(slt)
LHK: LHK_01558 LHK_01752
RSO: RSc0883 RSc3192
RPI: Rpic_2043
RPF: Rpic12D_1735
REH: H16_B1313
BPM: BURPS1710b_1695
BPL: BURPS1106A_1421
BPD: BURPS668_A2335
BTE: BTH_I1920
BAM: Bamb_4258
BAC: BamMC406_4784
BMJ: BMULJ_00931 BMULJ_01441
AAV: Aave_1729
DAC: Daci_4670
VAP: Vapar_2493
CTT: CtCNB1_2654 CtCNB1_3552
HAR: HEAR2266
MMS: mma_2728 mma_2788
NEU: NE2534
APP: CAP2UW1_0591
HPY: HP0339
DDE: Dde_3421
RCO: RC1298
RFE: RF_0924
RBE: RBE_0409
RBO: A1I_05700
SMD: Smed_6523
RET: RHE_CH01113(ypch00360)
REC: RHECIAT_CH0001188
RLE: RL3920
LAS: CLIBASIA_04790
OCA: OCAR_6584
BHE: BH13940
BQU: BQ11590
BBK: BARBAKC583_0240 BARBAKC583_1057
BTR: Btr_0306 Btr_0315 Btr_0482 Btr_1119 Btr_2229 Btr_2265
AZC: AZC_2137
MEX: Mext_1416
SIT: TM1040_1305
HNE: HNE_1271
ACR: Acry_0875
MAG: amb3986
AZL: AZL_b05450
SPH: MGAS10270_Spy0722(mur1-1) MGAS10270_Spy0723(mur1-2)
SPI: MGAS10750_Spy0754(mur1-1) MGAS10750_Spy0755(mur1-2)
SPJ: MGAS2096_Spy0734(mur1-1) MGAS2096_Spy0735(mur1-2)
SPK: MGAS9429_Spy0718(mur1-1) MGAS9429_Spy0719(mur1-2)
     MGAS9429_Spy0849
SPR: spr1431(lytC)
LPL: lp_1138(acm1) lp_2645(acm2) lp_3093
LSA: LSA1788
LSL: LSL_0296 LSL_0304 LSL_0797 LSL_0805 LSL_1310
LFE: LAF_1820
OOE: OEOE_1199
CAC: CA_C0554(lyc)
CNO: NT01CX_2099
SEN: SACE_3764 SACE_7138
CPI: Cpin_5913
SYN: slr0795
SYG: sync_1433 sync_1864
SYX: SynWH7803_0779
CYT: cce_0006
ANA: alr1167
AVA: Ava_4421
PMF: P9303_18641
TER: Tery_4178 Tery_4180
CCH: Cag_0702
PPH: Ppha_0875
Taxonomy
Reference
  Authors
  Title
  Journal
  Organism
 1  [PMID:4382801]
Blake CC, Johnson LN, Mair GA, North AC, Phillips DC, Sarma VR.
Crystallographic studies of the activity of hen egg-white lysozyme.
Proc. R. Soc. Lond. B. Biol. Sci. 167 (1967) 378-88.
Gallus gallus [GN:gga]
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:4382800]
Blake CC, Mair GA, North AC, Phillips DC, Sarma VR.
On the conformation of the hen egg-white lysozyme molecule.
Proc. R. Soc. Lond. B. Biol. Sci. 167 (1967) 365-77.
Gallus gallus [GN:gga]
Reference
  Authors
  Title
  Journal

 3
Jolles, P.
Lysozyme.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 4, Academic Press, New York, 1960, p. 431-445.
Other DBs ExplorEnz - The Enzyme Database: 3.2.1.17
IUBMB Enzyme Nomenclature: 3.2.1.17
ExPASy - ENZYME nomenclature database: 3.2.1.17
BRENDA, the Enzyme Database: 3.2.1.17
CAS: 9001-63-2
DBGET integrated database retrieval system