| Entry |
|
|---|
| Name |
alpha-N-acetylgalactosaminidase;
alpha-acetylgalactosaminidase;
N-acetyl-alpha-D-galactosaminidase;
N-acetyl-alpha-galactosaminidase |
|---|
| Class |
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl
compounds
 |
|---|
| Sysname |
alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase |
|---|
| Reaction(IUBMB) |
Hydrolysis of terminal non-reducing N-acetyl-D-galactosamine
residues in N-acetyl-alpha-D-galactosaminides |
|---|
| Reaction(KEGG) |
(other) R04183 R05966(G)
 |
|---|
| Comment |
Splits N-acetylgalactosaminyl groups from O-3 of Ser and Thr. |
|---|
| Pathway |
ec00603 Glycosphingolipid biosynthesis - globo series |
|---|
| Orthology |
K01204 alpha-N-acetylgalactosaminidase |
|---|
| Genes |
HSA: 4668(NAGA)
PTR: 470279(NAGA)
MCC: 713068(NAGA)
MMU: 17939(Naga)
RNO: 315165(Naga)
CFA: 481226(NAGA)
BTA: 533357(NAGA)
SSC: 100142667(NAGA)
ECB: 100070793(NAGA)
MDO: 100018362
GGA: 396547(NAGA)
TGU: 100229129
XLA: 443592(nagab)
XTR: 779501(naga)
DRE: 560778(MGC123333)
CIN: 100182270
SPU: 587840
DME: Dmel_CG5731
AGA: AgaP_AGAP009621
AME: 725899(GB10294)
API: 100161679(ACYPI002881)
NVE: NEMVE_v1g170108
TET: TTHERM_00136050
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6006833]
Tuppy H, Staudenbauer WL.
The action on soluble blood group A substances of an
alpha-N-acetylgalactosaminidase from Helix pomatia.
Biochemistry. 5 (1966) 1742-7.
Helix pomatia |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:5785223]
Weissmann B, Hinrichsen DF.
Mammalian alpha-acetylgalactosaminidase. Occurrence, partial
purification, and action on linkages in submaxillary mucins.
Biochemistry. 8 (1969) 2034-43.
Bos taurus [GN:bta] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:5348072]
Werries E, Wollek E, Gottschalk A, Buddecke E.
Separation of N-acetyl-alpha-glucosaminidase and
N-acetyl-alpha-galactosaminidase from ox spleen. Cleavage of the
O-glycosidic linkage between carbohydrate and polypeptide in ovine
and bovine submaxillary glycoprotein by
N-acetyl-alpha-galactosaminidase.
Eur. J. Biochem. 10 (1969) 445-9.
Bos taurus [GN:bta] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.2.1.49
IUBMB Enzyme Nomenclature: 3.2.1.49
ExPASy - ENZYME nomenclature database: 3.2.1.49
BRENDA, the Enzyme Database: 3.2.1.49
CAS: 9075-63-2 |
|---|
