KEGG   ENZYME: 3.2.1.68Help
Entry
EC 3.2.1.68                 Enzyme                                 

Name
isoamylase;
debranching enzyme;
glycogen alpha-1,6-glucanohydrolase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
glycogen 6-alpha-D-glucanohydrolase
Reaction(IUBMB)
Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limit dextrins
Reaction(KEGG)
(other) R11261
Show
Comment
Also readily hydrolyses amylopectin. Differs from EC 3.2.1.41 (pullulanase) and EC 3.2.1.142 (limit dextrinase) by its inability to hydrolyse pullulan, and by limited action on alpha-limit dextrins. Maltose is the smallest sugar it can release from an alpha-(1->6)-linkage.
History
EC 3.2.1.68 created 1972, modified 1976, modified 2000
Orthology
K01214  
isoamylase
Genes
TAD: 
ATH: 
AT2G39930(ISA1) AT4G09020(ISA3)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj1g3v1525840.1(Lj1g3v1525840.1) Lj4g3v3015110.2(Lj4g3v3015110.2) Lj4g3v3015110.3(Lj4g3v3015110.3)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0002s10110g(POPTRDRAFT_754756) POPTR_0006s07010g(POPTRDRAFT_560622) POPTR_0018s13240g(POPTRDRAFT_1107375)
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4346068(ISA) 4347328(OJ1595_D08.13-1)
DOSA: 
Os08t0520900-00(Os08g0520900) Os09t0469400-01(Os09g0469400)
OBR: 
BDI: 
SBI: 
SORBI_07g027200(SORBIDRAFT_07g027200)
ZMA: 
103649172 103654472 542095(iso3) 542318(isoamylase)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CVR: 
APRO: 
CME: 
GSL: 
CCP: 
SMIN: 
v1.2.031381.t1(symbB.v1.2.031381.t1)
PNL: 
 » show all
Taxonomy
Reference
1  [PMID:5456995]
  Authors
Yokobayashi K, Misaki A, Harada T.
  Title
Purification and properties of Pseudomonas isoamylase.
  Journal
Biochim. Biophys. Acta. 212 (1970) 458-69.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9067-73-6

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