KEGG   ENZYME: 3.6.3.3Help
Entry
EC 3.6.3.3                  Enzyme                                 
Name Cd2+-exporting ATPase
Class Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of
substances
BRITE hierarchy
Sysname ATP phosphohydrolase (Cd2+-exporting)
Reaction(IUBMB) ATP + H2O + Cd2+in = ADP + phosphate + Cd2+out [RN:R00086]
Reaction(KEGG) R00086
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Substrate ATP [CPD:C00002];
H2O [CPD:C00001];
Cd2+ [CPD:C01413]
Product ADP [CPD:C00008];
phosphate [CPD:C00009];
Cd2+ [CPD:C01413]
Comment A P-type ATPase that undergoes covalent phosphorylation during the
transport cycle. This enzyme occurs in protozoa, fungi and plants.
Orthology KO: K01532  Cd2+-exporting ATPase
Genes HMG: 100209559
ATH: AT2G19110(HMA4) AT4G30110(HMA2)
ECO: b3469(zntA)
ECJ: JW3434(zntA)
ECE: Z4843(zntA)
ECS: ECs4318(zntA)
ECF: ECH74115_4789(zntA)
ETW: ECSP_4425(zntA)
ECG: E2348C_3709(zntA)
ECC: c4262(zntA)
ECI: UTI89_C3984(zntA)
ECP: ECP_3562(zntA)
ECV: APECO1_2985(zntA)
ECW: EcE24377A_3951(zntA)
ECX: EcHS_A3668(zntA)
ECM: EcSMS35_3752(zntA)
ECY: ECSE_3737(zntA)
ECK: EC55989_3877(zntA)
ECQ: ECED1_4142(zntA)
ECR: ECIAI1_3616(zntA)
ECT: ECIAI39_3950(zntA)
ECZ: ECS88_3872(zntA)
EUM: ECUMN_3931(zntA)
ELF: LF82_3723(zntA)
EBR: ECB_03318(zntA)
STY: STY4235(zntA)
STT: t3946(zntA)
SPT: SPA3427(zntA)
SEK: SSPA3198(zntA)
SPQ: SPAB_04441(zntA)
SEI: SPC_3645(zntA)
SEC: SC3505(zntA)
SEW: SeSA_A3768(zntA)
SED: SeD_A3948(zntA)
SET: SEN3399(zntA)
STM: STM3576(zntA)
YPE: YPO3820(zntA)
YPK: y0410(zntA)
YPM: YP_3228(zntA)
YPA: YPA_0202(zntA)
YPN: YPN_0144(zntA)
YPG: YpAngola_A0571(zntA)
YPP: YPDSF_3437(zntA)
YPS: YPTB0215(zntA)
YPI: YpsIP31758_0233(zntA)
YPY: YPK_3985(zntA)
YPB: YPTS_0230(zntA)
YEN: YE0218(zntA)
SFL: SF3487(zntA)
SFX: S4276(zntA)
SFV: SFV_3472(zntA)
SSN: SSON_3707(zntA)
SBO: SBO_3466(zntA)
SBC: SbBS512_E3853(zntA)
SDY: SDY_3620(zntA)
ECA: ECA4352(zntA)
ETA: ETA_32820(zntA)
PLU: plu4108(zntA)
PAY: PAU_03733(zntA)
SGL: SG1853
ENT: Ent638_3873(zntA)
ESA: ESA_04268(zntA)
CTU: Ctu_39780(zntA)
KPN: KPN_03835(zntA)
KPE: KPK_0278(zntA)
KPU: KP1_5172(zntA)
CKO: CKO_04898(zntA)
SPE: Spro_0209(zntA)
PMR: PMI3600(zntA)
EIC: NT01EI_0127
ETR: ETAE_0137(zntA)
DDA: Dd703_3445
DZE: Dd1591_3564
VCH: VC1033(zntA)
VCO: VC0395_A0551(zntA)
VVU: VV1_2063(zntA)
VVY: VV2378(zntA)
VPA: VP0959(zntA)
VFI: VF_1522(zntA)
PPR: PBPRA1220(zntA)
PAE: PA3690
PAU: PA14_16660(cadA)
PAP: PSPA7_1448(cadA2)
PAG: PLES_12941 PLES_26261 PLES_26991
PPU: PP_5139(cadA-2)
PPF: Pput_5012
PPG: PputGB1_5192
PPW: PputW619_0326
PST: PSPTO_5279(cadA-1)
PSB: Psyr_4837
PSP: PSPPH_4869
PFL: PFL_5892
PFO: Pfl01_5371
PFS: PFLU5813
PEN: PSEEN5232(cadA)
PMY: Pmen_4225
PSA: PST_0664(cadA-2)
AVN: Avin_18520
PCR: Pcryo_1347
SFR: Sfri_3462
SHW: Sputw3181_1126
LPN: lpg1009(cadA-1) lpg1010
LPF: lpl1049(cadA2)
LPP: lpp2370(cadA2)
LPC: LPC_1843 LPC_2268
TGR: Tgr7_2810
MMW: Mmwyl1_1611(zntA)
AHA: AHA_0629(zntA)
ASA: ASA_0629(zntA)
TAU: Tola_1749
AFE: Lferr_0209
CVI: CV_1154(zntA)
LHK: LHK_00449(cadA-1)
RSO: RS05448(RSp0319)
RPI: Rpic_1643
RPF: Rpic12D_5284
REU: Reut_B3972
REH: H16_B1644(cadA)
RME: Rmet_2303 Rmet_5947
CTI: RALTA_B1454
BMA: BMA2976(cadA)
BMV: BMASAVP1_A3333(cadA)
BML: BMA10229_A1563(cadA)
BMN: BMA10247_3038(cadA)
BPS: BPSL3378
BPM: BURPS1710b_0150(cadA)
BPL: BURPS1106A_4019(cadA)
BPD: BURPS668_3946
BPR: GBP346_A4119
BTE: BTH_I3290
BVI: Bcep1808_0131
BUR: Bcep18194_A3304 Bcep18194_C7188
BCN: Bcen_2931
BCH: Bcen2424_0124
BCM: Bcenmc03_0138
BCJ: BCAL0055
BAM: Bamb_0114
BAC: BamMC406_0124
BMU: Bmul_0123
BMJ: BMULJ_03143(zntA)
BXE: Bxe_A4439
BPY: Bphyt_0026
BGL: bglu_1g00910
PNU: Pnuc_1677
BPE: BP2722
BPA: BPP1430
BBR: BB2504
BPT: Bpet2873
BAV: BAV1632(cadA)
RFR: Rfer_0854
PNA: Pnap_4001
AAV: Aave_1815
AJS: Ajs_1242 Ajs_1335
DAC: Daci_0479
DIA: Dtpsy_1151 Dtpsy_2148
VAP: Vapar_3562
HAR: HEAR0519 HEAR1542 HEAR1592 HEAR1616
MMS: mma_1796(zntA1)
NET: Neut_0084
DAR: Daro_2257 Daro_2631
TMZ: Tmz1t_2103
MFA: Mfla_2550
APP: CAP2UW1_4507 CAP2UW1_4544
HPY: HP0791
HPJ: jhp0727(hmcT)
HPA: HPAG1_0776
HHE: HH0586
HAC: Hac_0913(yvgW)
GSU: GSU2147
PPD: Ppro_3683
DMA: DMR_12750
SFU: Sfum_3773
MLO: mll2475
MES: Meso_2849 Meso_4129 Meso_4212
PLA: Plav_3390 Plav_3467
SME: SMc04128
SMD: Smed_3336
ATU: Atu0843
ATC: AGR_C_1540
ARA: Arad_2044
AVI: Avi_5561
RET: RHE_CH03719(ypch01333)
REC: RHECIAT_CH0003992
RLT: Rleg2_3501
RLG: Rleg_3796
RHI: NGR_c34490
BME: BMEI0053
BMF: BAB1_2019(cadA-1)
BMB: BruAb1_1993(cadA-1)
BMC: BAbS19_I18920
BMS: BR2018(cadA-1)
BMT: BSUIS_A1859
BOV: BOV_1942(cadA-2)
BCS: BCAN_A2064
OAN: Oant_0921 Oant_3208
BBT: BBta_7259(zntA) BBta_7421
RPA: RPA3260
RPD: RPD_1505 RPD_3643
RPT: Rpal_3679
NWI: Nwi_3134
NHA: Nham_3727 Nham_4535
OCA: OCAR_4019(cadA3) OCAR_4884(cadA)
XAU: Xaut_3338 Xaut_3978
AZC: AZC_1456
MEA: Mex_1p2601(zntA) Mex_2p0089
MPO: Mpop_4071 Mpop_4117
MCH: Mchl_1000 Mchl_1096
BID: Bind_0269
RSP: RSP_1791
RSQ: Rsph17025_3411
RSK: RSKD131_0094
PDE: Pden_0212 Pden_3295
DSH: Dshi_3609
RRU: Rru_A1027
BHA: BH4036
BWE: BcerKBAB4_2204
BCL: ABC0269
OIH: OB0276
GKA: GK0352 GK0585 GK0750
GTN: GTNG_0637
GWC: GWCH70_0549 GWCH70_1718
SAR: SAR0723(cadA)
SEP: SE0075
SSP: SSP1603 SSPP217
LMO: lmo1100(cadA)
LIN: pli0061
LSP: Bsph_4333
MCL: MCCL_0284
BBE: BBR47_03360
LLA: L63697(yuiA)
LLC: LACR_1042
LLM: llmg_0690 llmg_1561
SPZ: M5005_Spy_1167
SPB: M28_Spy1161
SAG: SAG1257
SUB: SUB1181
LPL: lp_3435(cadA)
LJO: LJ1696
LAC: LBA0541(cadA)
LSA: LSA0425 LSA1784
LSL: LSL_1786(zntA)
LBU: LBUL_0427
LBR: LVIS_0691
LCA: LSEI_0070
LCB: LCABL_00670(cadA)
LGA: LGAS_0981
LFE: LAF_1702
PPE: PEPE_0411
OOE: OEOE_0348
LME: LEUM_A03
LCI: LCK_p200034(cadA)
AMT: Amet_3997
AOE: Clos_2048
SWO: Swol_2086
DRM: Dred_1527
PTH: PTH_0233(zntA)
ACL: ACL_0428
CGL: NCgl1129(cgl1176) NCgl2871(cgl2974)
CGB: cg1329(ctpC) cg3295
CGT: cgR_0129
CEF: CE0077
KRH: KRH_07320
MLU: Mlut_09580
NCA: Noca_1662
RXY: Rxyl_0593 Rxyl_1801
GFO: GFO_0024 GFO_0269 GFO_1200
FNU: FN1190
OTE: Oter_4451
RBA: RB4891
ANA: alr7622
AVA: Ava_1125 Ava_3859
RRS: RoseRS_0463 RoseRS_2450
RCA: Rcas_2242
CAU: Caur_0868
CAG: Cagg_2698
CHL: Chy400_0942
TRO: trd_1776
DRA: DR_A0073
DGE: Dgeo_2581 Dgeo_2752
DDR: Deide_02560(cadA)
MAC: MA3632(cadA)
MEM: Memar_1349
MPL: Mpal_2322
MST: Msp_0121
HAL: VNG0149G(zntA)
HSL: OE1245F(cadA)
HMA: pNG6019(cadA) pNG6081(zntA1)
HWA: HQ2252A(cadA)
NPH: NP0258A(tpa02)
HLA: Hlac_2084
RCI: RCIX1787 RCIX2335(cadA)
Taxonomy
Structures PDB: 1MWY  1MWZ  2AJ0  2AJ1  
Reference
  Authors
  Title
  Journal
  Organism
 1  [PMID:7843081]
Silver S, Ji G.
Newer systems for bacterial resistances to toxic heavy metals.
Environ. Health. Perspect. 102 Suppl 3 (1994) 107-13.
Staphylococcus aureus, Bacillus firmus
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:8373163]
Tsai KJ, Linet AL.
Formation of a phosphorylated enzyme intermediate by the cadA
Cd(2+)-ATPase.
Arch. Biochem. Biophys. 305 (1993) 267-70.
Bacillus subtilis [GN:bsu]
Other DBs ExplorEnz - The Enzyme Database: 3.6.3.3
IUBMB Enzyme Nomenclature: 3.6.3.3
ExPASy - ENZYME nomenclature database: 3.6.3.3
BRENDA, the Enzyme Database: 3.6.3.3
DBGET integrated database retrieval system