| Entry |
|
|---|
| Name |
vesicle-fusing ATPase
|
|---|
| Class |
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to facilitate cellular and subcellular movement
 |
|---|
| Sysname |
ATP phosphohydrolase (vesicle-fusing)
|
|---|
| Reaction(IUBMB) |
ATP + H2O = ADP + phosphate [RN: R00086]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
|
|---|
| Comment |
A large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (_A_TPase _a_ssociated with a variety of cell _a_ctivities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger's syndrome.
|
|---|
| Orthology |
|
|---|
| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AGA: | | AAG: | | CQU: | | AME: | | NVI: | | TCA: | | API: | | PHU: | | ISC: | | CEL: | | CBR: | | BMY: | | TSP: | | SMM: | | NVE: | | HMG: | | TAD: | | AQU: | | ATH: | | ALY: | | GMX: | | MTR: | | CSV: | | RCU: | | POP: | | VVI: | | OSA: | | DOSA: | | BDI: | | SBI: | | ZMA: | | SMO: | | PPP: | | CRE: | | VCN: | | OLU: | | OTA: | | CME: | | SCE: | | AGO: | | ERC: | | KLA: | | LTH: | | PPA: | | VPO: | | ZRO: | | CGR: | | NCS: | | NDI: | | TPF: | | TBL: | | TDL: | | KAF: | | DHA: | | PIC: | | PGU: | | LEL: | | CAL: | | CTP: | | CDU: | | COT: | | YLI: | | CLU: | | NCR: | | SMP: | | PAN: | | TTT: | | MTM: | | MGR: | | FGR: | | NHE: | | VAL: | | SSL: | | BFU: | | ANI: | | NFI: | | AFM: | | AOR: | | ANG: | | AFV: | | ACT: | | PCS: | | CIM: | | CPW: | | PBL: | | URE: | | ABE: | | TVE: | | AJE: | | PNO: | | PTE: | | ZTR: | | TML: | | SPO: | | CNE: | | CNB: | | CGI: | | LBC: | | MPR: | | CCI: | | SCM: | | UMA: | | MGL: | | PGR: | | ECU: | | EIN: | | EHE: | | NCE: | | MBR: | | NGR: | | DDI: | | DPP: | | EHI: | | EDI: | | PFA: | | PFD: | | PFH: | | PYO: | | PCB: | | PBE: | | PKN: | | PVX: | | PCY: | | TAN: | | TPV: | | BBO: | | CPV: | | CHO: | | TGO: | | TET: | | PTM: | | TBR: | | TCR: | | LMA: | | LIF: | | LDO: | | LMI: | | LBZ: | | GLA: | | TVA: | | PTI: | | TPS: | | PIF: | | PCA: | | BRA: | | SWO: | | DRM: | | MTA: | | FAL: | |
» show all
 |
|---|
| Reference |
|
|---|
| Authors |
Confalonieri F, Duguet M. |
|---|
| Title |
A 200-amino acid ATPase module in search of a basic function. |
|---|
| Journal |
Bioessays. 17 (1995) 639-50. |
|---|
| Organism |
Homo sapiens [GN: hsa], Saccharomyces cerevisiae [GN: sce], Escherichia coli [GN: eco] |
|---|
| Reference |
|
|---|
| Authors |
Imamura A, Tamura S, Shimozawa N, Suzuki Y, Zhang Z, Tsukamoto T, Orii T, Kondo N, Osumi T, Fujiki Y. |
|---|
| Title |
Temperature-sensitive mutation in PEX1 moderates the phenotypes of peroxisome deficiency disorders. |
|---|
| Journal |
Hum. Mol. Genet. 7 (1998) 2089-94. |
|---|
| Organism |
|
|---|
| Reference |
|
|---|
| Authors |
Babst M, Wendland B, Estepa EJ, Emr SD. |
|---|
| Title |
The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. |
|---|
| Journal |
EMBO. J. 17 (1998) 2982-93. |
|---|
| Organism |
Saccharomyces cerevisiae [GN: sce] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |
|---|
