KEGG   ENZYME: 4.1.1.17Help
Entry
EC 4.1.1.17                 Enzyme                                 
Name ornithine decarboxylase;
SpeC;
L-ornithine carboxy-lyase
Class Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname L-ornithine carboxy-lyase (putrescine-forming)
Reaction(IUBMB) L-ornithine = putrescine + CO2 [RN:R00670]
Reaction(KEGG) R00670
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Substrate L-ornithine [CPD:C00077]
Product putrescine [CPD:C00134];
CO2 [CPD:C00011]
Cofactor Pyridoxal phosphate [CPD:C00018]
Comment A pyridoxal-phosphate protein.
Pathway ec00330  Arginine and proline metabolism
ec00480  Glutathione metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology K01581  ornithine decarboxylase
Genes HSA: 4953(ODC1)
PTR: 459027(ODC1)
MCC: 694559(ODC1) 695625(ODC1) 705256
MMU: 18263(Odc1)
RNO: 24609(Odc1)
CFA: 475666(ODC1)
BTA: 281365(ODC1)
SSC: 414408(ODC)
ECB: 100072405
MDO: 100027936
OAA: 100093130
GGA: 421937(ODC1)
TGU: 100229742
XLA: 379379(adc) 379859(odc1)
XTR: 448028(odc1)
DRE: 114426(odc1)
BFO: BRAFLDRAFT_87824
SPU: 589060
DME: Dmel_CG8719(Odc2) Dmel_CG8721(Odc1)
DPO: Dpse_GA21280
DAN: Dana_GF13654
DER: Dere_GG23323 Dere_GG23324
DPE: Dper_GL11482
DSE: Dsec_GM11484
DSI: Dsim_GD15360
DWI: Dwil_GK21743
DYA: Dyak_GE19168 Dyak_GE19169
DGR: Dgri_GH21896
DMO: Dmoj_GI20395
DVI: Dvir_GJ22122
AGA: AgaP_AGAP011805
AAG: AaeL_AAEL000044 AaeL_AAEL007880
CQU: CpipJ_CPIJ008556 CpipJ_CPIJ010688 CpipJ_CPIJ010690
AME: 410043(GB14750)
NVI: 100120787(NV11125)
TCA: 656985
API: 100167299(ACYPI008106)
PHU: Phum_PHUM228260
ISC: IscW_ISCW022761
CEL: K11C4.4(odc-1)
CBR: CBG19040(Cbr-odc-1)
BMY: Bm1_56455
NVE: NEMVE_v1g3350 NEMVE_v1g96024
HMG: 100202037
TAD: TRIADDRAFT_27475
POP: POPTR_1079795
RCU: RCOM_1599650 RCOM_1599660
VVI: 100249162
OSA: 4347746(Os09g0543400)
SBI: SORBI_02g031570
ZMA: 100274319
CRE: CHLREDRAFT_206067(ODC1)
OLU: OSTLU_31322(ODC1)
CME: CMA052C
SCE: YKL184W(SPE1)
AGO: AGOS_AER087C
KLA: KLLA0B02673g
LTH: KLTH0D15114g
PPA: PAS_chr3_0417
VPO: Kpol_1055p58
ZRO: ZYRO0B13112g
CGR: CAGL0D00484g
DHA: DEHA2D09614g
PIC: PICST_90612(SPE1)
PGU: PGUG_04702
LEL: LELG_01350
CTP: CTRG_04383
CDU: CD36_00660
YLI: YALI0B11330g
CLU: CLUG_00965
NCR: NCU01271
PAN: PODANSg8052
MGR: MGG_02441(MG02441.4)
FGR: FG05903.1
SSL: SS1G_12207
BFU: BC1G_01799
ANI: AN3846.2
AFM: AFUA_4G08010 AFUA_7G08450 AFUA_8G06540
NFI: NFIA_099170 NFIA_108190
AOR: AO090023000771
ANG: An04g02420
AFV: AFLA_111800 AFLA_138430
ACT: ACLA_047370 ACLA_053230
PCS: Pc13g07510 Pc21g18390
CIM: CIMG_08778 CIMG_09566
URE: UREG_02767 UREG_04756
PNO: SNOG_03643
TML: GSTUM_00011982001
SPO: SPAC144.04c(spe1)
CNE: CNC04890
CNB: CNBC2270
LBC: LACBIDRAFT_190490
CCI: CC1G_08100
UMA: UM01048.1
MGL: MGL_0475
MBR: MONBRDRAFT_28648 MONBRDRAFT_32398
NGR: NAEGRDRAFT_30077 NAEGRDRAFT_80669
DDI: DDB_G0281109(odc)
EHI: EHI_100430(36.t00008)
EDI: EDI_129800
PBE: PB300842.00.0
TET: TTHERM_00462900
PTM: GSPATT00007427001
TBR: Tb11.01.5300
LMA: LmjF12.0280
LIF: LinJ12.0100
LBZ: LbrM12_V2.0300
GLA: GL50803_94582
TVA: TVAG_257110 TVAG_258030 TVAG_351660
PTI: PHATRDRAFT_12642(ODC2)
TPS: THAPSDRAFT_32477(ODC1)
ECO: b0693(speF) b2965(speC)
ECJ: JW0680(speF) JW5482(speC)
ECD: ECDH10B_0759(speF) ECDH10B_3148(speC)
EBW: BWG_0552(speF) BWG_2687(speC)
ECE: Z0839(speF) Z4310(speC)
ECS: ECs0721 ECs3841
ECF: ECH74115_0785(speF) ECH74115_4269(speC)
ETW: ECSP_0738(speF) ECSP_3937(speC)
EOJ: ECO26_0755(speF) ECO26_4067(speC)
EOI: ECO111_0711(speF) ECO111_3716(speC)
EOH: ECO103_0687(speF) ECO103_3548(speC)
ECG: E2348C_0582(speF) E2348C_3218(speC)
EOK: G2583_0851(speF) G2583_3624(speC)
ECC: c0777(speF) c3553(speC)
ECP: ECP_0711 ECP_2959
ECI: UTI89_C0695(speF) UTI89_C3356(speC)
ECV: APECO1_1374(speF) APECO1_3536(speC)
ECX: EcHS_A3126(speC)
ECW: EcE24377A_0718(speF) EcE24377A_3311(speC)
ECM: EcSMS35_0715(speF) EcSMS35_3109(speC)
ECY: ECSE_0752 ECSE_3234
ECR: ECIAI1_0669(speF) ECIAI1_3098(speC)
ECQ: ECED1_0672(speF) ECED1_3428(speC)
ECK: EC55989_0677(speF) EC55989_3258(speC)
ECT: ECIAI39_0651(speF) ECIAI39_3389(speC)
EUM: ECUMN_3320(speC)
ECZ: ECS88_0727(speF) ECS88_3248(speC)
ECL: EcolC_0749 EcolC_2963
EBR: ECB_00649(speF) ECB_02795(speC)
EBD: ECBD_0772 ECBD_2968
EFE: EFER_2418(speF) EFER_2908(speC)
STY: STY0739(speF) STY3270(speC)
STM: STM0701(speF) STM3114(speC)
SPT: SPA2040(speF) SPA2977(speC)
SEK: SSPA1901 SSPA2776
SPQ: SPAB_02837 SPAB_03882
SEI: SPC_0710(speF) SPC_3181(speC)
SEC: SC0721(speF) SC3055(speC)
SEH: SeHA_C0822 SeHA_C3355(speC)
SEE: SNSL254_A0761 SNSL254_A3363(speC)
SEW: SeSA_A0858 SeSA_A3289(speC)
SEA: SeAg_B0748 SeAg_B3278(speC)
SED: SeD_A0809(speF) SeD_A3458
SEG: SG0698(speF)
SET: SEN0665(speF) SEN2958(speC)
SES: SARI_02240 SARI_04532
YPE: YPO0960(speC)
YPK: y3347(speC)
YPA: YPA_0304
YPN: YPN_3158
YPM: YP_3481(speC)
YPP: YPDSF_0554
YPG: YpAngola_A0159(speC)
YPZ: YPZ3_0768(speC)
YPS: YPTB3232(speC)
YPI: YpsIP31758_0811(speC)
YPY: YPK_0811
YPB: YPTS_3367
YEN: YE0455(speF) YE3447(speC) YE3527(speF2)
SFL: SF2962(speC)
SFX: S3165(speC)
SFV: SFV_3024(speC)
SSN: SSON_0644(speF) SSON_3230(speC)
SBO: SBO_0554(speF)
SDY: SDY_3107(speC)
ECA: ECA0967(speC)
PCT: PC1_0872
PWA: Pecwa_3418
ETA: ETA_28500(speC)
EPY: EpC_30030(speC)
EAM: EAMY_0578(speC)
EAY: EAM_2850(speC)
EBI: EbC_36860(speC)
ENT: Ent638_1205 Ent638_3380
ENC: ECL_03025 ECL_04303
ESA: ESA_00314 ESA_02646
CTU: Ctu_13080(speF) Ctu_35710(speC)
KPN: KPN_03397(speC)
KPE: KPK_0712(speC)
KPU: KP1_4678(speC)
KVA: Kvar_0684
CKO: CKO_02469 CKO_04340
CRO: ROD_06991(speF) ROD_50221(speC)
SPE: Spro_0509 Spro_4047
PMR: PMI0307(speF)
EIC: NT01EI_3411
ETR: ETAE_0260(speF)
DDA: Dd703_3033
DDC: Dd586_0882
DZE: Dd1591_3210
PAM: PANA_3238(speC)
HIN: HI0591(speF)
HIQ: CGSHiGG_06325
HSO: HS_1573(speF)
HSM: HSM_0438
PMU: PM0806(speF)
VCH: VCA1063
VCO: VC0395_0179(speF)
VCM: VCM66_A1021(speF)
VCJ: VCD_000277
VVU: VV2_1030 VV2_1235
VVY: VVA0063 VVA1524
VPA: VPA1635
VHA: VIBHAR_04833
VEX: VEA_001092
VFM: VFMJ11_A1103
VSA: VSAL_II1066(speF)
PAE: PA4519(speC)
PAU: PA14_58630(speC)
PAP: PSPA7_5135
PAG: PLES_48991(speC)
PPU: PP_0864
PPF: Pput_0894
PPG: PputGB1_0908
PPW: PputW619_4314
PST: PSPTO_4572
PSB: Psyr_2547 Psyr_4247
PSP: PSPPH_2704 PSPPH_4273
PFL: PFL_0867
PFO: Pfl01_0801
PFS: PFLU0811
PEN: PSEEN1035
PMY: Pmen_0801
PSA: PST_0994
AVN: Avin_12320(speC)
PAR: Psyc_0029
PCR: Pcryo_0037
PRW: PsycPRwf_1157
ACI: ACIAD2768
ACB: A1S_2571
MCT: MCR_0011
SON: SO_0314(speF) SO_4136
SAZ: Sama_0410 Sama_3334
SBL: Sbal_4084
SBM: Shew185_0465 Shew185_4053
SBN: Sbal195_0486 Sbal195_4171
SBP: Sbal223_0489 Sbal223_3975
SLO: Shew_3392
SPC: Sputcn32_3679
SHE: Shewmr4_3507 Shewmr4_3667
SHM: Shewmr7_0278
SHN: Shewana3_3871
SHW: Sputw3181_3821
MAQ: Maqu_0077
PIN: Ping_1416
CBU: CBU_0722
CBS: COXBURSA331_A0840
CBD: CBUD_0731
CBG: CbuG_1280
CBC: CbuK_1538
TCX: Tcr_0274
MMW: Mmwyl1_2175
AHA: AHA_1270
ASA: ASA_1256(odc)
TAU: Tola_0853
DNO: DNO_0014
REU: Reut_A0689
BUR: Bcep18194_B2075
BCN: Bcen_4358
BCH: Bcen2424_4008
BCM: Bcenmc03_3515
BCJ: BCAM1111(speF)
BXE: Bxe_C0745
BPH: Bphy_6445
AJS: Ajs_2762
MPT: Mpe_A1925
NEU: NE0909(speC)
NET: Neut_1387
NMU: Nmul_A1964
MFA: Mfla_1059
DAL: Dalk_1504
DAT: HRM2_10190
PUB: SAR11_0204(speC)
MLO: mll1584 mll2974
MES: Meso_2027 Meso_2715
PLA: Plav_2895 Plav_3234
SME: SMa0680 SMa0682 SMc02983
SMD: Smed_2772 Smed_5195
ATU: Atu3196(speF)
ARA: Arad_3911
AVI: Avi_3377 Avi_3806(speF)
RET: RHE_CH03629(ypch01283)
REC: RHECIAT_CH0000121 RHECIAT_CH0003899
RLE: RL4156
RLT: Rleg2_3390
RLG: Rleg_3689
RHI: NGR_c29260(speF)
BME: BMEII1133
BMI: BMEA_B0103
BMF: BAB2_0098
BMB: BruAb2_0099
BMC: BAbS19_II00910
BMS: BRA0100
BMT: BSUIS_B0106
BOV: BOV_A0092
BCS: BCAN_B0104(ldc)
BMR: BMI_II100
OAN: Oant_4245
BJA: bll3177 blr7759(speF)
BRA: BRADO4919(speF) BRADO6260
BBT: BBta_1349 BBta_3132(speF)
RPA: RPA0870 RPA2051
RPB: RPB_4547
RPC: RPC_4837
RPD: RPD_0856
RPE: RPE_3166 RPE_4802
RPT: Rpal_0938 Rpal_2341
NWI: Nwi_0924
NHA: Nham_3419
OCA: OCAR_4918
BHE: BH12730
BQU: BQ10050(odc)
BBK: BARBAKC583_1090
BTR: Btr_1749(ldc)
BGR: Bgr_15560
XAU: Xaut_0640 Xaut_2140 Xaut_2733
AZC: AZC_0333 AZC_3019
SNO: Snov_3939
MEX: Mext_0993 Mext_2045
MEA: Mex_1p0770 Mex_1p2027
MDI: METDI1141 METDI2810
MRD: Mrad2831_4404 Mrad2831_4655
MET: M446_0446
MPO: Mpop_0934 Mpop_2006
MCH: Mchl_0956 Mchl_2320
MNO: Mnod_0286 Mnod_1649
BID: Bind_0928 Bind_1080
MSL: Msil_0224 Msil_1157
CCR: CC_0360
CCS: CCNA_00365
CAK: Caul_0258
CSE: Cseg_3776
PZU: PHZ_c3319
BSB: Bresu_3251
SIL: SPO0364
SIT: TM1040_3110
RSP: RSP_1991
RSH: Rsph17029_0701
RSQ: Rsph17025_3089
RSK: RSKD131_0293
RCP: RCAP_rcc00493(ldc)
JAN: Jann_0801
PDE: Pden_2321
DSH: Dshi_1375
MMR: Mmar10_0377
HBA: Hbal_0825 Hbal_1471
ZMO: ZMO1020
ZMN: Za10_0285
NAR: Saro_1794
SAL: Sala_1197
SWI: Swit_4664
SJP: SJA_C1-17260(speF)
GOX: GOX0440
GBE: GbCGDNIH1_0522
ACR: Acry_2180
GDI: GDI_1352
GDJ: Gdia_2057
APT: APA01_25160
RRU: Rru_A1693
RCE: RC1_1357(ldc) RC1_1717 RC1_3009(ldc)
MAG: amb1108 amb1388
AZL: AZL_006200(speF) AZL_014440(speF) AZL_e00690(speF)
SLG: SLGD_00246
LJO: LJ1843
LJF: FI9785_1797(speF)
LAC: LBA0996
LSL: LSL_0138
LDB: Ldb0547 Ldb1775
LBU: LBUL_0489 LBUL_1645
LCA: LSEI_1654
LCB: LCABL_18700(speF)
LCZ: LCAZH_1644
LGA: LGAS_1881
LHE: lhv_1093 lhv_1785
LRH: LGG_01698(speF)
LRL: LC705_01682(speF)
LCR: LCRIS_01073(speC)
SLP: Slip_1552
AFN: Acfer_0135
NFA: nfa37850
SRT: Srot_2174
SCO: SCO6035(SC1C3.23)
NML: Namu_5043
SEN: SACE_1266 SACE_4334(odc)
SVI: Svir_24620
AMD: AMED_5152(speC)
AMI: Amir_5654
TDE: TDE1109
FNU: FN0501
OTE: Oter_0693
RBA: RB8469(odc)
PLM: Plim_3803
TAI: Taci_0576
ACO: Amico_0342
PPH: Ppha_0879
AAE: aq_728(speC)
HYA: HY04AAS1_1510
HTH: HTH_1160(speC)
TAL: Thal_0347
TMA: TM1873
TPT: Tpet_0924
TLE: Tlet_0147
TRQ: TRQ2_0946
TNA: CTN_0808
TNP: Tnap_0630
TME: Tmel_1333
TAF: THA_1674
FNO: Fnod_0684
PMO: Pmob_0531
KOL: Kole_1584
TYE: THEYE_A1762
MAC: MA2728
MBA: Mbar_A2177
MMA: MM_3185
MMH: Mmah_1889
MBN: Mboo_1046
MPL: Mpal_2447
HMA: rrnAC0198(odc)
KCR: Kcr_0504
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:5073764]
Ono M, Inoue H, Suzuki F, Takeda Y.
Studies on ornithine decarboxylase from the liver of
thioacetamide-treated rats. Purification and some properties.
Biochim. Biophys. Acta. 284 (1972) 285-97.
Rattus norvegicus [GN:rno]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:16747854]
Taylor ES, Gale EF.
Studies on bacterial amino-acid decarboxylases: 6. Codecarboxylase
content and action of inhibitors.
Biochem. J. 39 (1945) 52-8.
Clostridium septicum
Other DBs ExplorEnz - The Enzyme Database: 4.1.1.17
IUBMB Enzyme Nomenclature: 4.1.1.17
ExPASy - ENZYME nomenclature database: 4.1.1.17
BRENDA, the Enzyme Database: 4.1.1.17
CAS: 9024-60-6
DBGET integrated database retrieval system