KEGG   ENZYME: 4.1.1.19Help
Entry
EC 4.1.1.19                 Enzyme                                 
Name arginine decarboxylase;
SpeA;
L-arginine carboxy-lyase
Class Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname L-arginine carboxy-lyase (agmatine-forming)
Reaction(IUBMB) L-arginine = agmatine + CO2 [RN:R00566]
Reaction(KEGG) R00566
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Substrate L-arginine [CPD:C00062]
Product agmatine [CPD:C00179];
CO2 [CPD:C00011]
Cofactor Pyridoxal phosphate [CPD:C00018]
Comment A pyridoxal-phosphate protein.
Pathway ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology K01583  arginine decarboxylase
K01584  arginine decarboxylase
K01585  arginine decarboxylase
K02626  arginine decarboxylase
Genes HSA: 113451(ADC)
PTR: 469170(ADC)
MMU: 242669(Adc)
RNO: 366473(RGD1564776)
CFA: 478144(ADC)
BTA: 506961(ADC)
SSC: 100144439(SADC)
ECB: 100070043
ATH: AT2G16500(ADC1) AT4G34710(ADC2)
OSA: 4334917(Os04g0107600) 4340008(Os06g0131300)
ECO: b2938(speA) b4117(adiA)
ECJ: JW2905(speA) JW5731(adiA)
ECD: ECDH10B_3113(speA)
EBW: BWG_2660(speA) BWG_3830(adiA)
ECE: Z4283(speA) Z5719(adiA)
ECS: ECs3814 ECs5099
ECF: ECH74115_4241(speA) ECH74115_5631(adiA)
ETW: ECSP_3909(speA) ECSP_5216(adiA)
EOJ: ECO26_4037(speA) ECO26_5229(adiA)
EOI: ECO111_3686(speA) ECO111_4987(adiA)
EOH: ECO103_3518(speA) ECO103_4869(adiA)
ECG: E2348C_3191(speA) E2348C_4445(adiA)
EOK: G2583_3597(speA) G2583_4943(adiA)
ECC: c3524(speA) c4501 c5122(adiA)
ECP: ECP_2933 ECP_4360
ECI: UTI89_C3327(speA) UTI89_C4711(adiA)
ECV: APECO1_2264 APECO1_2334(adiA) APECO1_3590(speA)
ECX: EcHS_A3096(speA) EcHS_A4358(adiA)
ECW: EcE24377A_3281(speA) EcE24377A_4671(adiA)
ECM: EcSMS35_3081(speA) EcSMS35_4583(adiA)
ECY: ECSE_3207 ECSE_4415
ECR: ECIAI1_3071(speA) ECIAI1_4347(adiA)
ECQ: ECED1_3401(speA) ECED1_3435 ECED1_4851(adiA)
ECK: EC55989_3231(speA) EC55989_4608(adiA)
ECT: ECIAI39_3358(speA) ECIAI39_4541(adiA)
EUM: ECUMN_3290(speA) ECUMN_4649(adiA)
ECZ: ECS88_3221(speA) ECS88_4619(adiA) ECS88_4709
ECL: EcolC_0773 EcolC_3910
EBR: ECB_02768(speA) ECB_03988(adiA)
EBD: ECBD_0800 ECBD_3914
EFE: EFER_2878(speA)
STY: STY3240(speA) STY4495(adi)
STT: t2999(speA) t4203(adi)
STM: STM3086(speA) STM4296(adi)
SPT: SPA2950(speA) SPA4114(adi)
SEK: SSPA2749 SSPA3821
SPQ: SPAB_03850 SPAB_05298
SEI: SPC_3150(speA)
SEC: SC3026(speA) SC4175(adi)
SEH: SeHA_C3325(speA) SeHA_C4642(adiA)
SEE: SNSL254_A3333(speA) SNSL254_A4642(adiA)
SEW: SeSA_A3260(speA) SeSA_A4551(adiA)
SEA: SeAg_B3249(speA) SeAg_B4560(adiA)
SED: SeD_A3430(speA) SeD_A4691(adiA)
SEG: SG2981(speA) SG4141(adi)
SET: SEN2930(speA) SEN4067(adi)
SES: SARI_03361 SARI_04559
YPE: YPO0929(speA) YPO1201
YPK: y2987(adiA) y3313(speA)
YPA: YPA_0336 YPA_0913
YPN: YPN_2775 YPN_3126
YPM: YP_0936(adiA) YP_3513(speA)
YPP: YPDSF_0586 YPDSF_2494
YPG: YpAngola_A1325(adiA) YpAngola_A3349(speA)
YPZ: YPZ3_0797(speA) YPZ3_1108
YPS: YPTB1241 YPTB3202(speA)
YPI: YpsIP31758_0843(speA) YpsIP31758_2781(adiA)
YPY: YPK_0845 YPK_2860
YPB: YPTS_1329 YPTS_3333
YEN: YE3419(speA)
SFL: SF2931(speA) SF4106(adiA)
SFX: S3133(speA) S3624(adiA)
SFV: SFV_2993(speA) SFV_4113(adiA)
SSN: SSON_3092(speA) SSON_4292(adiA)
SBO: SBO_3051(speA) SBO_4144(adiA)
SBC: SbBS512_E3371(speA) SbBS512_E4614(adiA)
SDY: SDY_3134(speA) SDY_4094(adiA)
ECA: ECA3918(speA)
PCT: PC1_3706
PWA: Pecwa_3903
ETA: ETA_28250(speA)
EPY: EpC_29740(speA)
EAM: EAMY_0605(speA)
EAY: EAM_2825(speA)
EBI: EbC_36620(speA)
PLU: plu3319(adiA) plu3681(speA)
PAY: PAU_01088(speA) PAU_01321(adiA)
SGL: SG2018
ENT: Ent638_3344
ENC: ECL_04269
ESA: ESA_00402
CTU: Ctu_34750(speA)
KPN: KPN_03374(speA)
KPE: KPK_0737(speA)
KPU: KP1_4649(speA)
KVA: Kvar_0707
CKO: CKO_04316
CRO: ROD_50481(speA)
SPE: Spro_3973
PMR: PMI2094(speA)
EIC: NT01EI_0311 NT01EI_3374
ETR: ETAE_2963(speA)
HDE: HDEF_1524(speA)
DDA: Dd703_0550
DDC: Dd586_3627
DZE: Dd1591_0508
XBO: XBJ1_2247(adiA) XBJ1_3641(speA)
XNE: XNC1_1025(speA) XNC1_2066(adiA)
PAM: PANA_3209(speA)
PMU: PM1382(speA)
XFA: XF0144
XFT: PD0113(speA)
XFM: Xfasm12_0121
XFN: XfasM23_0106
XCC: XCC3868(speA)
XCB: XC_3953
XCA: xccb100_4055
XCV: XCV4038(speA)
XAC: XAC3923(speA)
XOO: XOO0220(speA)
XOM: XOO_0195
XOP: PXO_03648
XAL: XALc_0363(speA)
SML: Smlt2942 Smlt4364(speA)
SMT: Smal_2393 Smal_3768
VCH: VCA0815
VCO: VC0395_0419(speA)
VCM: VCM66_A0774(speA)
VCJ: VCD_000509
VVU: VV1_2356 VV1_2357
VVY: VV1986
VPA: VPA0170
VHA: VIBHAR_06737
VSP: VS_1238(speA)
VEX: VEA_000828
VFI: VF_A0840(speA)
VFM: VFMJ11_A0971(speA)
VSA: VSAL_II0254(speA)
PAE: PA1818 PA4839(speA)
PAU: PA14_41020(adi) PA14_63990(speA)
PAP: PSPA7_3478 PSPA7_5559(speA)
PAG: PLES_35091 PLES_52241(speA)
PPU: PP_0567(speA)
PPF: Pput_0606
PPG: PputGB1_0612 PputGB1_3712
PPW: PputW619_3465 PputW619_4598
PST: PSPTO_4842(speA)
PSB: Psyr_4381
PSP: PSPPH_4424(speA)
PFL: PFL_0679(speA) PFL_3293
PFO: Pfl01_0627 Pfl01_2188
PFS: PFLU0626(speA) PFLU2647
PEN: PSEEN4847(speA)
PMY: Pmen_0727
PSA: PST_0978(speA) PST_2250
CJA: CJA_1511(speA) CJA_3641
AVN: Avin_07050(speA) Avin_29580
ACI: ACIAD3341
SON: SO_1870(speA)
SDN: Sden_2280
SFR: Sfri_1698
SAZ: Sama_1963
SBL: Sbal_1768
SBM: Shew185_1761
SBN: Sbal195_1805
SBP: Sbal223_2517
SLO: Shew_1619
SPC: Sputcn32_1647
SSE: Ssed_2609
SPL: Spea_2480
SHE: Shewmr4_1557
SHM: Shewmr7_1632
SHN: Shewana3_1624
SHW: Sputw3181_2379
SHL: Shal_1803
SWD: Swoo_2057
SWP: swp_3024
SVO: SVI_2525(speA)
ILO: IL1213(speA)
PHA: PSHAa1075(speA) PSHAa2846(speA)
PAT: Patl_3873
SDE: Sde_1598
MAQ: Maqu_0520
AMC: MADE_03894
PIN: Ping_0861
TTU: TERTU_1610(speA)
LPN: lpg0006(speA)
LPF: lpl0006(speA)
LPP: lpp0006(speA)
LPC: LPC_0006(speA)
LPA: lpa_00006(speA)
LLO: LLO_0013(speA)
MCA: MCA2047(speA)
FTU: FTT_0432(speA)
FTF: FTF0432(speA)
FTL: FTL_0501
FTM: FTM_0587
NOC: Noc_0557
NHL: Nhal_3394
NWA: Nwat_0590
ALV: Alvin_2061
AEH: Mlg_0072
HHA: Hhal_2412
TGR: Tgr7_3124
TKM: TK90_0202
HNA: Hneap_1088
HCH: HCH_06406(speA)
CSA: Csal_0544
ABO: ABO_2398(speA)
MMW: Mmwyl1_2840
AHA: AHA_1613(speA)
ASA: ASA_2740(speA)
TAU: Tola_0379
AFE: Lferr_1186
AFR: AFE_1471(speA)
KKO: Kkor_1128
GPB: HDN1F_28030
NMA: NMA2017(speA)
NME: NMB0468(speA)
NMC: NMC1682(speA)
NMN: NMCC_1674(speA)
NMI: NMO_1574(speA)
NGO: NGO1487
NGK: NGK_1759
CVI: CV_2876(speA) CV_4040(adi)
LHK: LHK_01034(adi) LHK_01446(speA)
RSO: RSc2365(adi)
RSC: RCFBP_11056(adi)
RSL: RPSI07_1103(adi)
RPI: Rpic_2578
RPF: Rpic12D_2174
REH: H16_A2930(ldcC)
CTI: RALTA_A2412(adi)
BMA: BMA0715
BMV: BMASAVP1_A2298
BML: BMA10229_A2988
BMN: BMA10247_1611
BPS: BPSL1003
BPM: BURPS1710b_1216(adi)
BPL: BURPS1106A_1064
BPD: BURPS668_1058
BPR: GBP346_A1056
BTE: BTH_I0861
BUR: Bcep18194_B0779
BCM: Bcenmc03_2437 Bcenmc03_3514
BCJ: BCAL2641 BCAM1112(adiA)
BAC: BamMC406_2345 BamMC406_4861
BMU: Bmul_0862 Bmul_3701
BMJ: BMULJ_02396(ldcC) BMULJ_04816(ldcC)
BXE: Bxe_A3477
BPH: Bphy_2186 Bphy_6447
BPY: Bphyt_1020
BGL: bglu_1g08650 bglu_1g27980
BGE: BC1002_0737
PNE: Pnec_1204
BPE: BP0190
BPA: BPP0765
BBR: BB0850
BPT: Bpet4087(adi)
BAV: BAV0480(adiA) BAV2687(adiA)
DIA: Dtpsy_2252
DAC: Daci_2964
CTT: CtCNB1_1777
MMS: mma_1191(adi)
HSE: Hsero_3451(adiA)
LCH: Lcho_1886
TIN: Tint_1483
NET: Neut_2188
NMU: Nmul_A1040
EBA: ebA4413
DAR: Daro_0578
TMZ: Tmz1t_1590
TBD: Tbd_2106
MMB: Mmol_1529
MEH: M301_1109
MEI: Msip34_0887
APP: CAP2UW1_4030
SLT: Slit_2541
GCA: Galf_0413
HPY: HP0422
HPJ: jhp0962(speA)
HPA: HPAG1_0972
HPS: HPSH_05300
HPG: HPG27_951
HPP: HPP12_1002(speA)
HPB: HELPY_1006(speA)
HPL: HPB8_472(speA)
HHE: HH1233(speA)
HAC: Hac_0610(speA)
HMS: HMU02120(speA)
WSU: WS0554
TDN: Suden_1132
CJE: Cj0764c(speA)
CJR: CJE0855(speA)
CJJ: CJJ81176_0785(speA)
CJU: C8J_0715(speA)
CJD: JJD26997_1248(speA)
CFF: CFF8240_0895(speA)
CHA: CHAB381_0926(speA)
CCO: CCC13826_1273(speA)
CLA: Cla_0746(speA)
ABU: Abu_0964(speA)
ANT: Arnit_1968
SDL: Sdel_1289
NIS: NIS_0817(speA)
SUN: SUN_1360(speA)
NAM: NAMH_0363(speA)
GSU: GSU2537(speA)
GME: Gmet_0904
GUR: Gura_0983
GLO: Glov_1675
GBM: Gbem_2916
GEO: Geob_1678
GEM: GM21_1309
PCA: Pcar_2097(speA)
PPD: Ppro_2606
DVU: DVU0417(speA)
DVL: Dvul_2517
DVM: DvMF_1536
DDE: Dde_0571
DDS: Ddes_0901
DMA: DMR_23320(pdaD)
DBA: Dbac_2321
DRT: Dret_1314
BBA: Bd0364(speA)
DAK: DaAHT2_1220
DAL: Dalk_3766
DAT: HRM2_01420(speA)
ADE: Adeh_1896
ACP: A2cp1_2068
AFW: Anae109_1964
ANK: AnaeK_1983
MXA: MXAN_2742(speA)
SCL: sce2453(speA)
HOH: Hoch_0026
SAT: SYN_01184 SYN_01365 SYN_01577
SFU: Sfum_1025
DBR: Deba_0143
SME: SMa0680 SMa0682
SMD: Smed_5196
REC: RHECIAT_CH0000122
BJA: bll3177 blr3474
RPA: RPA2051
AZC: AZC_0983
MET: M446_1585
SIL: SPO0602(speA)
GBE: GbCGDNIH1_0522
MGM: Mmc1_0721
BSU: BSU14630(speA)
BCE: BC0035 BC3962
BLI: BL01634(speA)
BLD: BLi01681(speA)
BCL: ABC2407(speA)
BAY: RBAM_014490(speA)
SPV: SPH_1026
CTH: Cthe_1918 Cthe_2108
CDF: CD0888(speA) CD3551(speA)
CBO: CBO3116(speA)
CKL: CKL_3181(speA1)
CCE: Ccel_1119
SWO: Swol_0667
DRM: Dred_0487
DAE: Dtox_3568
PTH: PTH_0944
DAU: Daud_1980
TJR: TherJR_0604 TherJR_1055
HMO: HM1_1757(pdaD)
CHY: CHY_1622
MTA: Moth_0041
ADG: Adeg_0205
NTH: Nther_0886
MTU: Rv2531c
MTC: MT2607
MRA: MRA_2559
MTF: TBFG_12551
MTB: TBMG_01442(TBMG_01442.1)
MBO: Mb2560c
MBB: BCG_2553c
MBT: JTY_2547
MLE: ML0524(adi)
MLB: MLBr_00524(adi)
MPA: MAP1100(adi)
MAV: MAV_3408
MSM: MSMEG_0266
MMI: MMAR_2184
SCB: SCAB_0871
BCV: Bcav_0858
NML: Namu_5308
AMD: AMED_7450(ldcC)
SSM: Spirs_3255
LBI: LEPBI_I0693
LBF: LBF_0670(ldcC)
ABA: Acid345_1944
ACA: ACP_1744
SUS: Acid_7696
BTH: BT_3394
BFR: BF0239
BFS: BF0196
BVU: BVU_1337
PGN: PGN_1038
PDI: BDI_1202
APS: CFPG_110
PRU: PRU_2625(speA)
PMZ: HMPREF0659_A5136(speA)
RMR: Rmar_1413
CHU: CHU_1576(speA)
DFE: Dfer_3427
SLI: Slin_5527
CPI: Cpin_6223
PHE: Phep_2320
GFO: GFO_3625(speA)
FJO: Fjoh_2811
FPS: FP1708(speA)
FBA: FIC_02265
COC: Coch_1868
RBI: RB2501_05265
ZPR: ZPR_4206
CAT: CA2559_00525
BBL: BLBBGE_060(speA)
BPI: BPLAN_573(speA)
FSU: Fisuc_0501
OTE: Oter_3466
CAA: Caka_1533
MIN: Minf_2107(speA)
AMU: Amuc_1658
GAU: GAU_2051(speA)
RBA: RB3708(speA)
PSL: Psta_1856
PLM: Plim_3789
EMI: Emin_1537
SYN: slr0662(speA) slr1312(speA)
SYW: SYNW2359
SYC: syc0510_c
SYF: Synpcc7942_1037
SYD: Syncc9605_1621 Syncc9605_2513
SYE: Syncc9902_1380 Syncc9902_2172
SYG: sync_2742(speA)
SYR: SynRCC307_2378(speA)
SYX: SynWH7803_2389(speA)
SYP: SYNPCC7002_A1808(speA)
CYA: CYA_0128(speA)
CYB: CYB_2779(speA)
TEL: tll1807
MAR: MAE_46810
CYP: PCC8801_1650
CYC: PCC7424_4038
CYN: Cyan7425_3934
CYH: Cyan8802_1677
CYU: UCYN_05650
GVI: gll4070
ANA: all3401
NPU: Npun_F6279
AVA: Ava_2157 Ava_3423
NAZ: Aazo_1846
PMA: Pro0049(speA)
PMM: PMM0045
PMT: PMT2150
PMN: PMN2A_1378
PMI: PMT9312_0046 PMT9312_1095
PMB: A9601_00461(speA)
PMC: P9515_00521(speA)
PMF: P9303_28311(speA)
PMG: P9301_00481(speA)
PMH: P9215_00551(speA)
PMJ: P9211_00521(speA)
PME: NATL1_00591(speA)
TER: Tery_1142
AMR: AM1_1658(speA)
CTE: CT0562
CPC: Cpar_0586
CCH: Cag_0433 Cag_1160
CPH: Cpha266_0813 Cpha266_1029
CPB: Cphamn1_1809
CLI: Clim_0527
PVI: Cvib_1209
PLT: Plut_0567
PPH: Ppha_0860
PAA: Paes_0705
CTS: Ctha_2304
RRS: RoseRS_2839
RCA: Rcas_2474
CAU: Caur_1102
CAG: Cagg_1778
CHL: Chy400_1207
HAU: Haur_4514
DRA: DR_0243
DGE: Dgeo_1771
DDR: Deide_04410(speA)
TRA: Trad_0080
TTH: TTC1277
TTJ: TTHA1640
MRB: Mrub_2839
MSV: Mesil_3114
NDE: NIDE3973(pdaD)
DDF: DEFDS_1288
DAP: Dacet_2595
MJA: MJ_0316
MFE: Mefer_1277
MVU: Metvu_0499
MFS: MFS40622_1088
MMP: MMP1582(pdaD)
MMQ: MmarC5_1827
MMX: MmarC6_1088
MMZ: MmarC7_0829
MAE: Maeo_0604
MVN: Mevan_0894
MVO: Mvol_1150
MAC: MA3012 MA3496
MBA: Mbar_A2039 Mbar_A2492
MMA: MM_0286 MM_2595
MBU: Mbur_1870
MMH: Mmah_1890
MEV: Metev_1937
MTP: Mthe_1536
MHU: Mhun_0113
MLA: Mlab_0203
MEM: Memar_2150
MBN: Mboo_0144 Mboo_1176
MPL: Mpal_1878
MPD: MCP_0518(pdaD-1) MCP_1356(pdaD-2)
MTH: MTH870
MMG: MTBMA_c12650(pdaD)
MST: Msp_1327(pdaD)
MSI: Msm_0878
MRU: mru_1743(pdaD)
MKA: MK0740
AFU: AF2301 AF2431
APO: Arcpr_0349
FPL: Ferp_0861 Ferp_1436
HAL: VNG1999H
HSL: OE3803R(pdaD)
HMA: rrnAC3199(argDC)
HWA: HQ3114A(pdaD)
NPH: NP4484A
HLA: Hlac_2010
HUT: Huta_2601
HMU: Hmuk_1309
HTU: Htur_3361
NMG: Nmag_1363
HVO: HVO_1958
HJE: HacjB3_04565
TAC: Ta0778
TVO: TVN0762
PTO: PTO1192
PHO: PH1609
PAB: PAB0382
PFU: PF1623
TKO: TK0149
TON: TON_1323
TGA: TGAM_0581(pdaD)
TSI: TSIB_0849
ABI: Aboo_0500
RCI: RRC25(speA)
SMR: Smar_0204
SHC: Shell_0616
DKA: DKAM_0651
TAG: Tagg_0502
TPE: Tpen_0872
NMR: Nmar_1180
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:4870599]
Blethen SL, Boeker EA, Snell EE.
Argenine decarboxylase from Escherichia coli. I. Purification and
specificity for substrates and coenzyme.
J. Biol. Chem. 243 (1968) 1671-7.
Escherichia coli [GN:eco]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:1252]
Ramakrishna S, Adiga PR.
Arginine decarboxylase from Lathyrus sativus seedlings. Purification
and properites.
Eur. J. Biochem. 59 (1975) 377-86.
Lathyrus sativus
Reference
  Authors
  Title

  Journal
  Organism
 3  [PMID:16747854]
Taylor ES, Gale EF.
Studies on bacterial amino-acid decarboxylases: 6. Codecarboxylase
content and action of inhibitors.
Biochem. J. 39 (1945) 52-8.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 4.1.1.19
IUBMB Enzyme Nomenclature: 4.1.1.19
ExPASy - ENZYME nomenclature database: 4.1.1.19
BRENDA, the Enzyme Database: 4.1.1.19
CAS: 9024-77-5
DBGET integrated database retrieval system