KEGG   ENZYME: 4.1.1.45Help
Entry
EC 4.1.1.45                 Enzyme                                 
Name aminocarboxymuconate-semialdehyde decarboxylase;
picolinic acid carboxylase;
picolinic acid decarboxylase;
alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase;
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde
beta-decarboxylase;
2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase;
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase
Class Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase
(2-aminomuconate-semialdehyde-forming)
Reaction(IUBMB) 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate = 2-aminomuconate
semialdehyde + CO2 [RN:R04323]
Reaction(KEGG) R04323
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Substrate 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate [CPD:C04409]
Product 2-aminomuconate semialdehyde [CPD:C03824];
CO2 [CPD:C00011]
Comment Product rearranges non-enzymically to picolinate.
Pathway ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology K03392  aminocarboxymuconate-semialdehyde decarboxylase
Genes HSA: 130013(ACMSD)
PTR: 459627(ACMSD)
MCC: 708917(ACMSD)
MMU: 266645(Acmsd)
RNO: 171385(Acmsd)
CFA: 476125(ACMSD)
BTA: 515030(ACMSD)
ECB: 100050432
MDO: 100015778
GGA: 424288(ACMSD)
TGU: 100226130
DRE: 557166(acmsd)
CIN: 100178473
SPU: 583197
CEL: Y71D11A.3
CBR: CBG11728
NVE: NEMVE_v1g126268
PAN: PODANSg09797
AFM: AFUA_2G17440
AOR: AO090102000067
AFV: AFLA_001970 AFLA_079300
ACT: ACLA_076340
PCS: Pc20g02360
NFI: NFIA_092840
MBR: MONBRDRAFT_13314
NGR: NAEGRDRAFT_81621
DDI: DDB_G0286525(acmsd)
SWD: Swoo_1407
PAT: Patl_0847
KKO: Kkor_0379
REU: Reut_B5503
REH: H16_B0330(acmD)
RME: Rmet_5212
BVI: Bcep1808_6383
BUR: Bcep18194_B2954 Bcep18194_C7640
BCH: Bcen2424_0158
BCJ: BCAM2129(nbaD)
BAM: Bamb_4307
BXE: Bxe_C0621 Bxe_C0650
BPY: Bphyt_1472
POL: Bpro_5140
VAP: Vapar_0614
AZO: azo2542(fldW)
MXA: MXAN_0918
SNO: Snov_0217
CAK: Caul_1931
SWI: Swit_1753 Swit_3524
BCA: BCE_2152
BCX: BCA_2150
BTL: BALH_1839
BPF: BpOF4_12585
BMQ: BMQ_3592
BMD: BMD_3577
GTN: GTNG_3156(nbaD)
GYC: GYMC61_2293
GCT: GC56T3_2060
BBE: BBR47_29730
AAC: Aaci_1616
SDS: SDEG_2047
MVA: Mvan_0424
MJL: Mjls_4213
NFA: nfa32640
RER: RER_04740 RER_59370
ROP: ROP_46400(cmtD)
SCO: SCO6305(SCIF3.07c)
SCB: SCAB_15151 SCAB_90581
ACH: Achl_3548
KFL: Kfla_3148 Kfla_5490
SRO: Sros_4717 Sros_9109
NML: Namu_4102
STP: Strop_3521
SAQ: Sare_3896
CAI: Caci_7137
RXY: Rxyl_2240
CWO: Cwoe_3899
ABA: Acid345_0682
SUS: Acid_7161
CAT: CA2559_07440
TRO: trd_1095 trd_1402
STI: Sthe_0108
Taxonomy
Reference
  Authors

  Title


  Journal
  Organism
 1  [PMID:14275130]
ICHIYAMA A, NAKAMURA S, KAWAI H, HONJO T, NISHIZUKA Y, HAYAISHI O,
SENOH S.
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN
MAMMALIAN TISSUES. II. ENZYMIC FORMATION OF ALPHA-AMINOMUCONIC ACID
FROM 3-HYDROXYANTHRANILIC ACID.
J. Biol. Chem. 240 (1965) 740-9.
Felis catus
Other DBs ExplorEnz - The Enzyme Database: 4.1.1.45
IUBMB Enzyme Nomenclature: 4.1.1.45
ExPASy - ENZYME nomenclature database: 4.1.1.45
BRENDA, the Enzyme Database: 4.1.1.45
CAS: 37289-47-7
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