KEGG   ENZYME: 4.1.1.64Help
Entry
EC 4.1.1.64                 Enzyme                                 
Name
2,2-dialkylglycine decarboxylase (pyruvate);
dialkyl amino acid (pyruvate) decarboxylase;
alpha-dialkyl amino acid transaminase;
2,2-dialkyl-2-amino acid-pyruvate aminotransferase;
L-alanine-alpha-ketobutyrate aminotransferase;
dialkylamino-acid decarboxylase (pyruvate);
2,2-dialkylglycine carboxy-lyase (amino-transferring)
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)
Reaction(IUBMB)
2,2-dialkylglycine + pyruvate = dialkyl ketone + CO2 + L-alanine [RN:R03854]
Reaction(KEGG)
Substrate
2,2-dialkylglycine [CPD:C02623];
pyruvate [CPD:C00022]
Product
dialkyl ketone [CPD:C02146];
CO2 [CPD:C00011];
L-alanine [CPD:C00041]
Comment
A pyridoxal-phosphate protein. Acts on 2-amino-2-methylpropanoate (i.e. 2-methylalanine), 2-amino-2-methylbutanoate and 1-aminocyclopentanecarboxylate.
Orthology
K00596  
2,2-dialkylglycine decarboxylase (pyruvate)
Genes
BVI: 
BUR: 
BCN: 
BCH: 
BCM: 
BCJ: 
BAM: 
BAC: 
BCT: 
BXE: 
BPY: 
Bphyt_2046
BGD: 
bgla_2g24020
BYI: 
BYI23_C012020
BUK: 
MYA_2984
AXY: 
AXYL_05358(dgdA)
VPE: 
Varpa_4653
ADN: 
Alide_3099
ADK: 
Alide2_1348
MPT: 
Mpe_A1466
RGE: 
RGE_11320
SMD: 
Smed_5089
ATU: 
Atu5302
MRD: 
Mrad2831_2878
TMO: 
TMO_1799(dgdA)
LME: 
LEUM_0839
LMM: 
MI1_03880
MSM: 
MSMEG_6842
MSG: 
MSMEI_6659
MVA: 
Mvan_5803
GPO: 
GPOL_c48070
TPR: 
Tpau_3251
SCO: 
SCO7537(SC8G12.13c)
SVL: 
Strvi_5938
SRO: 
Sros_5114
NML: 
Namu_5409
SEN: 
SACE_2647
AMD: 
AMED_0279
AMN: 
RAM_01410
AMM: 
AMES_0274
PDX: 
Psed_5588
AMI: 
Amir_4825
SNA: 
Snas_1896
BTP: 
D805_0368
 » show all
Taxonomy
Reference
1
  Authors
Bailey, G.B. and Dempsey, W.B.
  Title
Purification and properties of an alpha-dialkyl amino acid transaminase.
  Journal
Biochemistry 6 (1967) 1526-1533.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9032-17-1
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