KEGG   ENZYME: 4.2.3.47Help
Entry
EC 4.2.3.47                 Enzyme                                 

Name
beta-farnesene synthase;
farnesene synthase;
terpene synthase 10;
terpene synthase 10-B73;
TPS10
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-beta-farnesene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (E)-beta-farnesene + diphosphate [RN:R08695]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(E)-beta-farnesene [CPD:C09666];
diphosphate [CPD:C00013]
History
EC 4.2.3.47 created 2010
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K12645  
epi-isozizaene 5-monooxygenase / beta-farnesene synthase
K14174  
beta-farnesene/exo-alpha-bergamotene synthase
K15793  
acyclic sesquiterpene synthase
K22064  
beta-farnesene synthase
Genes
CIT: 
BDI: 
SBI: 
ZMA: 
541974(tps1) 732751(tps10)
SITA: 
SCO: 
SCO5223(SC7E4.20)
SMA: 
SAV_3031(cyp14)
SHY: 
SHO: 
SDV: 
SALB: 
SALS: 
SCI: 
SLV: 
SGU: 
SCW: 
SAMB: 
SCX: 
SRW: 
STRF: 
SLE: 
sle_25170(sle_25170)
SPAV: 
STRT: 
SGS: 
STSI: 
SLS: 
SPLU: 
STRD: 
 » show all
Taxonomy
Reference
1  [PMID:19858213]
  Authors
Zhao B, Lei L, Vassylyev DG, Lin X, Cane DE, Kelly SL, Yuan H, Lamb DC, Waterman MR
  Title
Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site.
  Journal
J. Biol. Chem. 284 (2009) 36711-9.
  Sequence
[sco:SCO5223]
Reference
2  [PMID:15896363]
  Authors
Picaud S, Brodelius M, Brodelius PE
  Title
Expression, purification and characterization of recombinant (E)-beta-farnesene synthase from Artemisia annua.
  Journal
Phytochemistry. 66 (2005) 961-7.
Reference
3  [PMID:19646721]
  Authors
Kollner TG, Gershenzon J, Degenhardt J
  Title
Molecular and biochemical evolution of maize terpene synthase 10, an enzyme of indirect defense.
  Journal
Phytochemistry. 70 (2009) 1139-45.
Reference
4  [PMID:16418295]
  Authors
Schnee C, Kollner TG, Held M, Turlings TC, Gershenzon J, Degenhardt J
  Title
The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 1129-34.
  Sequence
[zma:732751]
Reference
5  [PMID:11642326]
  Authors
Maruyama T, Ito M, Honda G
  Title
Molecular cloning, functional expression and characterization of (E)-beta farnesene synthase from Citrus junos.
  Journal
Biol. Pharm. Bull. 24 (2001) 1171-5.
  Sequence
Reference
6  [PMID:9371761]
  Authors
Crock J, Wildung M, Croteau R.
  Title
Isolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint (Mentha x piperita, L.) that produces the aphid alarm pheromone (E)-beta-farnesene.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 12833-8.
Reference
7  [PMID:12481088]
  Authors
Schnee C, Kollner TG, Gershenzon J, Degenhardt J
  Title
The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage.
  Journal
Plant. Physiol. 130 (2002) 2049-60.
  Sequence
[zma:541974]
Reference
8  [PMID:15921711]
  Authors
Huber DP, Philippe RN, Godard KA, Sturrock RN, Bohlmann J
  Title
Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii.
  Journal
Phytochemistry. 66 (2005) 1427-39.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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