| Entry |
|
|---|
| Name |
dodecenoyl-CoA isomerase;
dodecenoyl-CoA Delta-isomerase;
Delta3-cis-Delta2-trans-enoyl-CoA isomerase;
acetylene-allene isomerase;
dodecenoyl-CoA Delta-isomerase;
dodecenoyl-CoA Delta3-cis-Delta2-trans-isomerase |
|---|
| Class |
Isomerases;
Intramolecular oxidoreductases;
Transposing C=C bonds
 |
|---|
| Sysname |
dodecenoyl-CoA (3Z)-(2E)-isomerase |
|---|
| Reaction(IUBMB) |
(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA [RN:R04100] |
|---|
| Reaction(KEGG) |
R04100;
(other) R04756
 |
|---|
| Substrate |
(3Z)-dodec-3-enoyl-CoA [CPD:C02944] |
|---|
| Product |
(2E)-dodec-2-enoyl-CoA [CPD:C03221] |
|---|
| Comment |
Also catalyses the interconversion of 3-acetylenic fatty acyl
thioesters and (+)-2,3-dienoyl fatty acyl thioesters, with fatty
acid chain lengths C6 to C12. |
|---|
| Pathway |
ec00071 Fatty acid metabolism |
|---|
| Orthology |
K01825 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase /
3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
K07514 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /
3,2-trans-enoyl-CoA isomerase
K13238 3,2-trans-enoyl-CoA isomerase, mitochondrial
K13239 peroxisomal 3,2-trans-enoyl-CoA isomerase |
|---|
| Genes |
HSA: 10455(PECI) 1632(DCI) 1962(EHHADH)
PTR: 460996(EHHADH) 471843(PECI) 750080(DCI)
MCC: 696243(DCI) 701193(EHHADH) 709579(PECI)
MMU: 13177(Dci) 23986(Peci) 74147(Ehhadh)
RNO: 171142(Ehhadh) 291075(Peci) 29740(Dci)
CFA: 478706(PECI) 488110(EHHADH) 490059(DCI)
BTA: 505355(PECI) 518852(EHHADH) 535174(DCI)
SSC: 100134957(PECI)
ECB: 100059161 100067714(EHHADH) 100068292
MDO: 100013071 100020890
OAA: 100079137 100082172
GGA: 416657(DCI) 420878(PECI) 424877(EHHADH)
TGU: 100218671 100223799 100229287
XLA: 432103(dci) 734873
XTR: 100216270(peci) 496654(dci)
DRE: 100000859(ehhadh) 436918(wu:fd61c12)
BFO: BRAFLDRAFT_220780 BRAFLDRAFT_57395 BRAFLDRAFT_57495
CIN: 100180101 100182323 100182913
SPU: 574788 592077
DME: Dmel_CG13890 Dmel_CG4598
DPO: Dpse_GA18288 Dpse_GA23791
DAN: Dana_GF15725 Dana_GF15726 Dana_GF24414
DER: Dere_GG10064 Dere_GG14742
DPE: Dper_GL16867 Dper_GL18943
DSE: Dsec_GM14360 Dsec_GM17765
DSI: Dsim_GD13579 Dsim_GD23637
DWI: Dwil_GK17361 Dwil_GK18281
DYA: Dyak_GE18878 Dyak_GE21104
DGR: Dgri_GH11302 Dgri_GH16867
DMO: Dmoj_GI11426 Dmoj_GI17722
DVI: Dvir_GJ13621 Dvir_GJ17550
AGA: AgaP_AGAP006651 AgaP_AGAP010130
AAG: AaeL_AAEL003709 AaeL_AAEL004755
CQU: CpipJ_CPIJ005435 CpipJ_CPIJ013796
AME: 552000(GB11035)
NVI: 100117797(NV14539) 100123009(NV12018)
TCA: 662039
API: 100162806(ACYPI003931) 100166810(ACYPI007651)
PHU: Phum_PHUM182320 Phum_PHUM470740
ISC: IscW_ISCW017077
CEL: R06F6.9(ech-4)
CBR: CBG03009(Cbr-ech-4)
BMY: Bm1_17680
NVE: NEMVE_v1g194333 NEMVE_v1g202353
HMG: 100212010 100214797
TAD: TRIADDRAFT_31655 TRIADDRAFT_60851
CRE: CHLREDRAFT_183312(ECH1)
OLU: OSTLU_28941
MBR: MONBRDRAFT_13701
NGR: NAEGRDRAFT_33361 NAEGRDRAFT_70586
PTM: GSPATT00015150001 GSPATT00037185001
TBR: Tb927.4.4910
TCR: 507107.40
LMA: LmjF31.2250
LIF: LinJ31.2690 LinJ31.3010
LBZ: LbrM31_V2.2520
PTI: PHATRDRAFT_18064
TPS: THAPSDRAFT_268835(ECI1)
ECO: b3846(fadB)
ECJ: JW3822(fadB)
ECD: ECDH10B_4035(fadB)
EBW: BWG_3522(fadB)
ECE: Z5367(fadB)
ECS: ECs4774(fadB)
ECF: ECH74115_5285(fadB)
ETW: ECSP_4899(fadB)
EOJ: ECO26_4741(fadB)
EOI: ECO111_4672(fadB)
EOH: ECO103_4319(fadB)
ECG: E2348C_4158(fadB)
EOK: G2583_4644(fadB)
ECC: c4793(fadB)
ECP: ECP_4059(fadB)
ECI: UTI89_C4431(fadB)
ECV: APECO1_2611(fadB)
ECX: EcHS_A4069(fadB)
ECW: EcE24377A_4365(fadB)
ECM: EcSMS35_4227(fadB)
ECY: ECSE_4132(fadB)
ECR: ECIAI1_4039(fadB)
ECQ: ECED1_4548(fadB)
ECK: EC55989_4321(fadB)
ECT: ECIAI39_3149(fadB)
EUM: ECUMN_4370(fadB)
ECZ: ECS88_4294(fadB)
ECL: EcolC_4164(fadB)
EBR: ECB_03737(fadB)
EBD: ECBD_4179(fadB)
EFE: EFER_3635(fadB)
STY: STY3577(fadB)
STT: t3315(fadB)
STM: STM3983(fadB)
SPT: SPA3823(fadB)
SEK: SSPA3560(fadB)
SPQ: SPAB_04939(fadB)
SEI: SPC_4090(fadB)
SEC: SC3880(fadB)
SEH: SeHA_C4309(fadB)
SEE: SNSL254_A4262(fadB)
SEW: SeSA_A4190(fadB)
SEA: SeAg_B4213(fadB)
SED: SeD_A4369(fadB)
SEG: SG3469(fadB)
SET: SEN3777(fadB)
SES: SARI_03676(fadB)
YPE: YPO3766(fadB)
YPK: y0464(fadB)
YPA: YPA_3436(fadB)
YPN: YPN_0198(fadB)
YPM: YP_3282(fadB)
YPP: YPDSF_3386(fadB)
YPG: YpAngola_A1912(fadB)
YPZ: YPZ3_3324(fadB)
YPS: YPTB0267(fadB)
YPI: YpsIP31758_0283(fadB)
YPY: YPK_3933(fadB)
YPB: YPTS_0283(fadB)
YEN: YE0268(fadB)
SFL: SF3922(fadB)
SFX: S3830(fadB)
SFV: SFV_3654(fadB)
SSN: SSON_4019(fadB)
SBC: SbBS512_E4316(fadB)
SDY: SDY_3899(fadB)
ECA: ECA0208(fadB)
PCT: PC1_4044(fadB)
PWA: Pecwa_4234(fadB)
ETA: ETA_02460(fadB)
EPY: EpC_02330(fadB)
EAM: EAMY_0223(fadB)
EAY: EAM_0213(fadB)
EBI: EbC_02440(fadB)
PLU: plu4402(fadB)
PAY: PAU_03873(fadB)
ENT: Ent638_3949(fadB)
ENC: ECL_04951
ESA: ESA_03714(fadB)
CTU: Ctu_02770(fadB)
KPN: KPN_04340(fadB)
KPE: KPK_5333(fadB)
KPU: KP1_0203(fadB)
KVA: Kvar_4892
CKO: CKO_00188(fadB)
CRO: ROD_39091(fadB)
SPE: Spro_0261(fadB)
PMR: PMI3550(fadB)
DDA: Dd703_3747(fadB)
DDC: Dd586_0200
DZE: Dd1591_3901(fadB)
XBO: XBJ1_0517(fadB)
XNE: XNC1_3875(fadB)
PAM: PANA_0201(fadB)
VCH: VC2758(fadB)
VCO: VC0395_A2534(fadB)
VCM: VCM66_2678(fadB)
VCJ: VCD_001454(fadB)
VVU: VV1_0981(fadB)
VVY: VV0029(fadB)
VPA: VP0030(fadB)
VHA: VIBHAR_00460(fadB)
VSP: VS_0041(fadB)
VEX: VEA_001988
VFI: VF_0025(fadB)
VFM: VFMJ11_0024(fadB)
VSA: VSAL_I2974(fadB)
PPR: PBPRA0064(fadB)
PAE: PA3014(fadB)
PAU: PA14_25080(fadB)
PAP: PSPA7_2145(fadB)
PAG: PLES_20481(fadB)
PPU: PP_2136(fadB)
PPF: Pput_3606(fadB)
PPG: PputGB1_1676(fadB)
PPW: PputW619_1652(fadB)
PST: PSPTO_3517(fadB)
PSB: Psyr_3290(fadB)
PSP: PSPPH_3210(fadB)
PFL: PFL_1940(fadB)
PFO: Pfl01_3879(fadB)
PFS: PFLU1553(fadB)
PEN: PSEEN3728(fadB)
PMY: Pmen_1580(fadB)
PSA: PST_1726(fadB)
AVN: Avin_14440(fadB)
PAR: Psyc_1934(fadB)
PCR: Pcryo_2227(fadB)
PRW: PsycPRwf_2100(fadB)
ACI: ACIAD0335(fadB)
ACD: AOLE_17905(fadB)
ABM: ABSDF3220(fadB)
ABY: ABAYE3470(fadB)
ABC: ACICU_00322(fadB)
ABN: AB57_0387(fadB)
ABB: ABBFA_003230(fadB)
MCT: MCR_0091(fadB)
SON: SO_0021(fadB)
SDN: Sden_0015(fadB)
SFR: Sfri_0013(fadB)
SAZ: Sama_0032(fadB)
SBL: Sbal_0021(fadB)
SBM: Shew185_0016(fadB)
SBN: Sbal195_0020(fadB)
SBP: Sbal223_0020(fadB)
SLO: Shew_0019(fadB)
SPC: Sputcn32_0013(fadB)
SSE: Ssed_0023(fadB)
SPL: Spea_0018(fadB)
SHE: Shewmr4_0018(fadB)
SHM: Shewmr7_0016(fadB)
SHN: Shewana3_0024(fadB)
SHW: Sputw3181_0013(fadB)
SHL: Shal_0016(fadB)
SWD: Swoo_0021(fadB)
SWP: swp_0035(fadB)
SVO: SVI_0052(fadB-1)
ILO: IL0011(fadB)
CPS: CPS_0393(fadB)
PHA: PSHAa0011(fadB)
PAT: Patl_0201(fadB)
SDE: Sde_1605(fadB)
MAQ: Maqu_1144(fadB)
AMC: MADE_03736(fadB)
TTU: TERTU_1620(fadB)
HCH: HCH_04756(fadB)
CSA: Csal_2393(fadB)
ABO: ABO_1652(fadB)
MMW: Mmwyl1_1578(fadB)
AHA: AHA_0139(fadB)
ASA: ASA_4250(fadB)
KKO: Kkor_0013(fadB)
GPB: HDN1F_10070(fadB)
DAR: Daro_2350(fadB)
HOH: Hoch_1660
MSL: Msil_1395(fadB)
AZL: AZL_a11100(fadB)
RBA: RB1092(faoA)
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:376522]
Miesowicz FM, Bloch K.
Purification of hog liver isomerase. Mechanism of isomerization of
3-alkenyl and 3-alkynyl thioesters.
J. Biol. Chem. 254 (1979) 5868-77.
Sus scofa [GN:ssc] |
|---|
Reference
Authors
Title
Journal
|
2 [PMID:5830064]
Stoffel W, Ditzer R, Caesar H.
[The metabolism of unsaturated fatty acid. 3. On the beta-oxidation
of mono- and polyene-fatty acids. The mechanism of the enzymatic
reaction on delta-3-cis-enoyl-CoA compounds]
Hoppe. Seylers. Z. Physiol. Chem. 339 (1964) 167-81. |
|---|
Reference
Authors
Title
Journal
|
3
Stoffel, W. and Ecker, W.
Delta3-cis,-Delta2-trans-Enoyl-CoA isomerase from rat liver
mitochondria.
Methods Enzymol. 14 (1979) 99-105. |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:738702]
Stoffel W, Grol M.
Purification and properties of 3-cis-2-trans-enoyl-CoA isomerase
(dodecenoyl-CoA delta-isomerase) from rat liver mitochondria.
Hoppe. Seylers. Z. Physiol. Chem. 359 (1978) 1777-82.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 5.3.3.8
IUBMB Enzyme Nomenclature: 5.3.3.8
ExPASy - ENZYME nomenclature database: 5.3.3.8
BRENDA, the Enzyme Database: 5.3.3.8
CAS: 62213-29-0 |
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